IT8622877A0 - AZONIASPIRONORTROPANOL ESTERS, PROCEDURE FOR THEIR PREPARATION, PHARMACEUTICAL MEANS THAT CONTAIN THEM AND USE OF AZONIASPIRONORTROPANOL ESTERS AS SPASMOLYTIC, ASMATTHERAPEUTIC AND BRONCHOLYTIC. - Google Patents

AZONIASPIRONORTROPANOL ESTERS, PROCEDURE FOR THEIR PREPARATION, PHARMACEUTICAL MEANS THAT CONTAIN THEM AND USE OF AZONIASPIRONORTROPANOL ESTERS AS SPASMOLYTIC, ASMATTHERAPEUTIC AND BRONCHOLYTIC.

Info

Publication number: IT8622877A0
Authority: IT; Italy
Prior art keywords: azoniaspironortropanol; esters; asmattherapeutic; broncholytic; spasmolytic
Prior art date: 1985-12-27

Application number

IT8622877A

Other languages

Italian (it)

Other versions

IT8622877A1 (en

IT1198263B (en

Inventor

Wolf Grimminger

Klaus Gorler

Karl Peter Odenthal

Original Assignee

Madaus & Co Dr

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-12-27

Filing date

1986-12-24

Publication date

1986-12-24

1985-12-27 Priority claimed from DE19853546218 external-priority patent/DE3546218A1/en

1985-12-27 Priority claimed from DE19853546165 external-priority patent/DE3546165A1/en

1986-12-24 Application filed by Madaus & Co Dr filed Critical Madaus & Co Dr

1986-12-24 Publication of IT8622877A0 publication Critical patent/IT8622877A0/en

1988-06-24 Publication of IT8622877A1 publication Critical patent/IT8622877A1/en

1988-12-21 Application granted granted Critical

1988-12-21 Publication of IT1198263B publication Critical patent/IT1198263B/en

Links

MXMOCKPTNSGRFA-ZACCUICWSA-N (1r,5s)-spiro[8-azoniabicyclo[3.2.1]octane-8,1'-azolidin-1-ium]-3-ol Chemical class [N+]12([C@@H]3CC[C@H]2CC(C3)O)CCCC1 MXMOCKPTNSGRFA-ZACCUICWSA-N 0.000 title 2
229940124630 bronchodilator Drugs 0.000 title 1
230000001813 broncholytic effect Effects 0.000 title 1
239000000812 cholinergic antagonist Substances 0.000 title 1
230000002048 spasmolytic effect Effects 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/20—Spiro-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed systems contains four or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/20—Spiro-condensed systems

IT22877/86A 1985-12-27 1986-12-24 ESTERS OF AZONIASPIRONORTROPANOL, PROCEDURE FOR THEIR PREPARATION, PHARMACEUTICAL MEDIA CONTAINING THEM AND USE OF ESTERS OF AZONIASPIRONORTROPANOL AS SPASMOLYTIC, ASMATHERAPEUTIC AND BRONCOLITIC IT1198263B (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE19853546218 DE3546218A1 (en)	1985-12-27	1985-12-27	AZONIA SPIRONORTROPANOLESTER, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL AGENT
DE19853546165 DE3546165A1 (en)	1985-12-27	1985-12-27	USE OF AZONIA SPIRONORTROPANOLESTERS AS ASTHMATHERAPEUTIC AND AS BRONCHOLYTIC

Publications (3)

Publication Number	Publication Date
IT8622877A0 true IT8622877A0 (en)	1986-12-24
IT8622877A1 IT8622877A1 (en)	1988-06-24
IT1198263B IT1198263B (en)	1988-12-21

Family

ID=25839393

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IT22877/86A IT1198263B (en)	1985-12-27	1986-12-24	ESTERS OF AZONIASPIRONORTROPANOL, PROCEDURE FOR THEIR PREPARATION, PHARMACEUTICAL MEDIA CONTAINING THEM AND USE OF ESTERS OF AZONIASPIRONORTROPANOL AS SPASMOLYTIC, ASMATHERAPEUTIC AND BRONCOLITIC

Country Status (18)

Country	Link
KR (1)	KR930000113B1 (en)
AT (1)	AT397962B (en)
AU (1)	AU584266B2 (en)
BE (1)	BE906054A (en)
CA (1)	CA1304369C (en)
CH (1)	CH677793A5 (en)
ES (1)	ES2004177A6 (en)
FI (1)	FI865295A (en)
FR (1)	FR2598417B1 (en)
GB (1)	GB2184726B (en)
HU (1)	HU201930B (en)
IT (1)	IT1198263B (en)
NL (1)	NL193184C (en)
PL (1)	PL150843B1 (en)
PT (1)	PT84022B (en)
SE (1)	SE8605531L (en)
SU (1)	SU1711674A3 (en)
YU (1)	YU46038B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2536401C (en) *	2003-11-04	2011-08-30	Shire Laboratories Inc.	Compositions of quaternary ammonium compounds containing bioavailability enhancers
US20060210625A1 (en) *	2003-11-04	2006-09-21	Shire Laboratories, Inc.	Sustained release of positively charged pharmacologically active molecules from a matrix containing polymers with polarized oxygen atoms
CN101684117B (en) *	2008-09-27	2013-06-12	宁波市医药技术研究有限公司	Method for preparing nor-tropine

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1194422B (en) *	1963-03-05	1965-06-10	Robert Pfleger Chem Fab Dr	Process for the production of azonia spironortropane derivatives
US3480626A (en) *	1967-05-18	1969-11-25	Chem Fab Dr R Pfleger	Certain azoniaspironortropine derivatives
DE1670258C3 (en) *	1967-08-04	1976-01-02	C.H. Boehringer Sohn, 6507 Ingelheim	Process for the preparation of norscopolamine by dealkylation of tertiary, cyclic amines
IT1140998B (en) *	1980-06-18	1986-10-10	Valeas Ind Chimica E Farmaceut	ENDO-8-METHYL-8-SIN-ALCHIL-8-AZONIABICYCLE OPEN SALTS PAR. SQUARE 3.2.1. CLOSED PAR. QUADRATA-OTTAN-3-ALCHILCARBOSSILATI, PROCESS FOR THEIR PREPARATION AND THERAPEUTIC COMPOSITIONS THAT CONTAIN THEM AS AN ACTIVE INGREDIENT

1986
- 1986-12-19 AT AT0339286A patent/AT397962B/en not_active IP Right Cessation
- 1986-12-22 CH CH5198/86A patent/CH677793A5/de not_active IP Right Cessation
- 1986-12-22 SE SE8605531A patent/SE8605531L/en not_active Application Discontinuation
- 1986-12-23 FI FI865295A patent/FI865295A/en not_active Application Discontinuation
- 1986-12-23 GB GB8630809A patent/GB2184726B/en not_active Expired - Fee Related
- 1986-12-23 PL PL1986263216A patent/PL150843B1/en unknown
- 1986-12-24 ES ES8603662A patent/ES2004177A6/en not_active Expired
- 1986-12-24 IT IT22877/86A patent/IT1198263B/en active
- 1986-12-24 PT PT84022A patent/PT84022B/en not_active IP Right Cessation
- 1986-12-24 AU AU66985/86A patent/AU584266B2/en not_active Ceased
- 1986-12-24 NL NL8603303A patent/NL193184C/en not_active IP Right Cessation
- 1986-12-25 YU YU224986A patent/YU46038B/en unknown
- 1986-12-26 FR FR8618210A patent/FR2598417B1/en not_active Expired - Fee Related
- 1986-12-26 SU SU864028726A patent/SU1711674A3/en active
- 1986-12-27 HU HU865367A patent/HU201930B/en not_active IP Right Cessation
- 1986-12-27 KR KR1019860011482A patent/KR930000113B1/en not_active IP Right Cessation
- 1986-12-29 CA CA000526376A patent/CA1304369C/en not_active Expired - Fee Related
- 1986-12-29 BE BE2/61142A patent/BE906054A/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
FI865295A (en)	1987-06-28
BE906054A (en)	1987-06-29
FR2598417A1 (en)	1987-11-13
GB2184726B (en)	1990-10-03
GB8630809D0 (en)	1987-02-04
CA1304369C (en)	1992-06-30
ATA339286A (en)	1993-12-15
GB2184726A (en)	1987-07-01
PL150843B1 (en)	1990-07-31
YU46038B (en)	1992-12-21
PL263216A1 (en)	1988-04-14
IT8622877A1 (en)	1988-06-24
FR2598417B1 (en)	1993-10-29
PT84022B (en)	1989-07-31
FI865295A0 (en)	1986-12-23
HUT43060A (en)	1987-09-28
SU1711674A3 (en)	1992-02-07
CH677793A5 (en)	1991-06-28
AU584266B2 (en)	1989-05-18
AT397962B (en)	1994-08-25
ES2004177A6 (en)	1988-12-16
PT84022A (en)	1987-01-01
NL193184B (en)	1998-10-01
NL193184C (en)	1999-02-02
SE8605531L (en)	1987-06-28
AU6698586A (en)	1987-07-02
NL8603303A (en)	1987-07-16
KR930000113B1 (en)	1993-01-09
SE8605531D0 (en)	1986-12-22
HU201930B (en)	1991-01-28
IT1198263B (en)	1988-12-21
KR870005998A (en)	1987-07-08
YU224986A (en)	1988-04-30

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Legal Events

Date	Code	Title	Description
1999-10-27	TA	Fee payment date (situation as of event date), data collected since 19931001	Effective date: 19971030