IT8221290A0 - Sintesi di corticoidi mediante acetilene alogenato metallato. - Google Patents
Sintesi di corticoidi mediante acetilene alogenato metallato.Info
- Publication number
- IT8221290A0 IT8221290A0 IT8221290A IT2129082A IT8221290A0 IT 8221290 A0 IT8221290 A0 IT 8221290A0 IT 8221290 A IT8221290 A IT 8221290A IT 2129082 A IT2129082 A IT 2129082A IT 8221290 A0 IT8221290 A0 IT 8221290A0
- Authority
- IT
- Italy
- Prior art keywords
- metallied
- corticoids
- synthesis
- acetylene
- halogenated
- Prior art date
Links
- HSFWRNGVRCDJHI-UHFFFAOYSA-N Acetylene Chemical class C#C HSFWRNGVRCDJHI-UHFFFAOYSA-N 0.000 title 1
- 230000015572 biosynthetic process Effects 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
- C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0033—Androstane derivatives substituted in position 17 alfa and 17 beta
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
- C07J5/0053—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
- C07J7/0085—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/264,759 US4342702A (en) | 1981-05-18 | 1981-05-18 | Metallated halogenated acetylene corticoid synthesis |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| IT8221290A0 true IT8221290A0 (it) | 1982-05-14 |
| IT8221290A1 IT8221290A1 (it) | 1983-11-14 |
| IT1152181B IT1152181B (it) | 1986-12-31 |
Family
ID=23007476
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT21290/82A IT1152181B (it) | 1981-05-18 | 1982-05-14 | Sintesi di corticoidi mediante acetilene alogenato metallato |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US4342702A (it) |
| JP (1) | JPS57193499A (it) |
| CH (1) | CH650517A5 (it) |
| DE (1) | DE3218289A1 (it) |
| FR (1) | FR2505847A1 (it) |
| GB (1) | GB2098614B (it) |
| HU (1) | HU186020B (it) |
| IT (1) | IT1152181B (it) |
| NL (1) | NL8201875A (it) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4357279A (en) * | 1981-05-18 | 1982-11-02 | The Upjohn Company | Preparation of corticoids from 17-keto steroids |
| US4404142A (en) * | 1981-05-18 | 1983-09-13 | The Upjohn Company | Preparation of corticoids from 17-keto steroids |
| US4401599A (en) * | 1981-05-18 | 1983-08-30 | The Upjohn Company | Preparation of 21-halo steroids |
| US4585590A (en) * | 1984-02-03 | 1986-04-29 | The Upjohn Company | Cyanohydrin process |
| US4500461A (en) * | 1984-02-03 | 1985-02-19 | The Upjohn Company | Cyanohydrin process |
| US4548748A (en) * | 1984-02-03 | 1985-10-22 | The Upjohn Company | Cyanohydrin process |
| US4831131A (en) * | 1984-02-03 | 1989-05-16 | The Upjohn Company | 11β,17α-Dihydroxy-17β-cyano-androstanes |
| US4600538A (en) * | 1984-08-02 | 1986-07-15 | The Upjohn Company | Corticosteroids from 17-keto steroids via 20-cyano-Δ17 (20)-pregnanes |
| DE3434448A1 (de) * | 1984-09-17 | 1986-03-27 | Schering AG, 1000 Berlin und 4709 Bergkamen | Verfahren zur herstellung von pregnan-derivaten |
| CA2425841C (en) * | 1991-11-22 | 2006-01-10 | Alcon Laboratories, Inc. | Angiostatic steroids |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3499013A (en) * | 1968-11-04 | 1970-03-03 | Searle & Co | 3-oxygenated 21beta-hydrocarbonsulfonyl-pregna-17(20),20-dienes,dehydro and 19-nor derivatives thereof and intermediates thereto |
| US4041055A (en) * | 1975-11-17 | 1977-08-09 | The Upjohn Company | Process for the preparation of 17α-hydroxyprogesterones and corticoids from androstenes |
| FR2374037A1 (fr) * | 1976-10-27 | 1978-07-13 | Roussel Uclaf | Nouveaux derives steroides 17-spirosultines les g-hydroxy acides correspondants, leur procede de preparation et leur application comme medicament |
| US4183924A (en) * | 1978-02-27 | 1980-01-15 | Schering Corporation | 17α-Chloro-17β-hydrocarbonsulfinyl-1,4-androstadienes and the corresponding 17β-hydrocarbonsulfonyl derivatives and their use as anti-acne agents |
-
1981
- 1981-05-18 US US06/264,759 patent/US4342702A/en not_active Expired - Fee Related
-
1982
- 1982-04-20 GB GB8211333A patent/GB2098614B/en not_active Expired
- 1982-05-07 NL NL8201875A patent/NL8201875A/nl not_active Application Discontinuation
- 1982-05-10 CH CH2895/82A patent/CH650517A5/de not_active IP Right Cessation
- 1982-05-14 DE DE19823218289 patent/DE3218289A1/de not_active Withdrawn
- 1982-05-14 IT IT21290/82A patent/IT1152181B/it active
- 1982-05-17 HU HU821546A patent/HU186020B/hu unknown
- 1982-05-17 FR FR8208551A patent/FR2505847A1/fr active Granted
- 1982-05-18 JP JP57083897A patent/JPS57193499A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| GB2098614B (en) | 1985-04-11 |
| IT1152181B (it) | 1986-12-31 |
| US4342702A (en) | 1982-08-03 |
| FR2505847A1 (fr) | 1982-11-19 |
| GB2098614A (en) | 1982-11-24 |
| DE3218289A1 (de) | 1982-12-02 |
| FR2505847B1 (it) | 1984-01-06 |
| IT8221290A1 (it) | 1983-11-14 |
| HU186020B (en) | 1985-05-28 |
| CH650517A5 (de) | 1985-07-31 |
| JPS57193499A (en) | 1982-11-27 |
| NL8201875A (nl) | 1982-12-16 |
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