IT8149476A0 - Procedimento per la produzione di alogenuri ammonici spiroquaternari e prodotti ottenuti - Google Patents

Procedimento per la produzione di alogenuri ammonici spiroquaternari e prodotti ottenuti

Info

Publication number: IT8149476A0
Authority: IT; Italy
Prior art keywords: spiroquaternary; procedure; production; products obtained; ammonium halides
Prior art date: 1980-10-16

Application number

IT8149476A

Other languages

English (en)

Other versions

IT1143244B (it

Inventor

Jack C Simms

Original Assignee

Bristol Myers Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1980-10-16

Filing date

1981-10-13

Publication date

1981-10-13

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22729338&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IT8149476(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1981-10-13 Application filed by Bristol Myers Co filed Critical Bristol Myers Co

1981-10-13 Publication of IT8149476A0 publication Critical patent/IT8149476A0/it

1986-10-22 Application granted granted Critical

1986-10-22 Publication of IT1143244B publication Critical patent/IT1143244B/it

Links

-1 AMMONIUM HALIDES Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/10—Spiro-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

IT49476/81A 1980-10-16 1981-10-13 Procedimento per la produzione di alogenuri ammonici spiroquaternari e prodotti ottenuti IT1143244B (it)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/197,416 US4351939A (en)	1980-10-16	1980-10-16	Spiro-quaternary ammonium halides and N-(2-pyrimidinyl)piperazinylalkylazaspiroalkanedione process

Publications (2)

Publication Number	Publication Date
IT8149476A0 true IT8149476A0 (it)	1981-10-13
IT1143244B IT1143244B (it)	1986-10-22

Family

ID=22729338

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IT49476/81A IT1143244B (it)	1980-10-16	1981-10-13	Procedimento per la produzione di alogenuri ammonici spiroquaternari e prodotti ottenuti

Country Status (33)

Country	Link
US (1)	US4351939A (it)
JP (2)	JPS5724384A (it)
KR (2)	KR890000465B1 (it)
AT (1)	AT382153B (it)
AU (1)	AU524822B2 (it)
BE (1)	BE890509A (it)
CA (1)	CA1175832A (it)
CH (1)	CH647778A5 (it)
CY (1)	CY1325A (it)
DE (1)	DE3141256C2 (it)
DK (1)	DK148481C (it)
ES (2)	ES501994A0 (it)
FI (1)	FI75159C (it)
FR (1)	FR2492383A1 (it)
GB (1)	GB2085436B (it)
GR (1)	GR74687B (it)
HK (1)	HK35386A (it)
HU (2)	HU187999B (it)
IE (1)	IE51646B1 (it)
IL (1)	IL64047A (it)
IT (1)	IT1143244B (it)
KE (1)	KE3596A (it)
LU (1)	LU83657A1 (it)
MY (1)	MY8600475A (it)
NL (2)	NL179055C (it)
NZ (1)	NZ196974A (it)
OA (1)	OA06920A (it)
PT (1)	PT73824B (it)
SE (2)	SE439167B (it)
SG (1)	SG97885G (it)
SU (1)	SU1342420A3 (it)
YU (2)	YU42565B (it)
ZA (1)	ZA812759B (it)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AT387221B (de) *	1980-09-08	1988-12-27	Bristol Myers Co	Verfahren zur herstellung des neuen
US4507303A (en) *	1981-12-22	1985-03-26	Sumitomo Chemical Company, Limited	Succinimide derivatives, compositions and method of use
US4452799A (en) *	1981-12-23	1984-06-05	Mead Johnson & Company	Benzisothiazole and benzisoxazole piperazine derivatives
JPS5945380U (ja) *	1982-09-20	1984-03-26	いすゞ自動車株式会社	車両用帯状体の固定装置
US5066783A (en) *	1986-05-20	1991-11-19	Cohen Eric A	Antiviral peptides and means for treating herpes infections
US5015646A (en) *	1987-08-28	1991-05-14	Bristol-Myers Squibb Co.	Pharmaceutically useful polymorphic modification of buspirone
US4810789A (en) *	1987-08-28	1989-03-07	Bristol-Myers Company	Process for buspirone hydrochloride polymorphic crystalline form conversion
US5631017A (en) *	1993-03-26	1997-05-20	Beth Israel Deaconess Medical Center, Inc.	Topical application of buspirone for treatment of pathological conditions associated with immune responses
US5484788A (en) *	1993-03-26	1996-01-16	Beth Israel Hospital Association	Buspirone as a systemic immunosuppressant
FR2705098B1 (fr) *	1993-05-10	1995-08-04	Esteve Labor Dr	Procédé de préparation de 2-{4-[4-(chloro-1-pyrazolyl)butyl]1-pipérazinyl}pyrimidine (Lesopitron) .
CA2146593A1 (en) *	1994-05-05	1995-11-06	Jack Melton	Large-scale process for azapirone synthesis
US5521313A (en) *	1994-05-05	1996-05-28	Bristol-Myers Squibb Company	Process for preparing certain azapirones
US5637314A (en) *	1995-06-07	1997-06-10	Beth Israel Deaconess Medical Center, Inc.	Topical and systemic application of buspirone or derivatives thereof for treating atopic dermatitis
AR038368A1 (es) *	2002-02-01	2005-01-12	Novartis Ag	Compuestos n-pirimidin-2-il-aminas sustituidas como inhibidores de ige, una composicion farmaceutica y el uso de dichos compuestos para la preparacion de un medicamento
ATE506366T1 (de) *	2005-08-30	2011-05-15	Honeywell Int Inc	Verfahren zur synthese von quaternären ammonium- spirosystemen
CN101089000B (zh) *	2006-06-16	2011-01-05	北京大学	螺环哌嗪季铵盐类化合物及其制备方法和应用
CN101362751B (zh) *	2007-08-10	2011-05-11	成都科瑞德医药投资有限责任公司	枸橼酸坦度螺酮及其制备方法、制剂和质量控制方法
WO2011136383A1 (en) *	2010-04-26	2011-11-03	Dainippon Sumitomo Pharma Co., Ltd.	A process of a quaternary ammonium salt
ES2527545T3 (es) *	2010-04-26	2015-01-26	Sumitomo Dainippon Pharma Co., Ltd.	Un procedimiento de preparación de una sal de amonio cuaternario utilizando fosfato
IT201900000657A1 (it)	2019-01-16	2020-07-16	Procos Spa	Processo per la sintesi di gepirone

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB948730A (en) *	1959-04-08	1964-02-05	Wellcome Found	Substituted cyclopropanes and related compounds
US3968216A (en) *	1969-10-29	1976-07-06	Smith Kline & French Laboratories Limited	Method of inhibiting histamine activity with guanidine compounds
BE759371A (fr) *	1969-11-24	1971-05-24	Bristol Myers Co	Azaspirodecanediones heterocycliques et procedes pour leur preparation

1980
- 1980-10-16 US US06/197,416 patent/US4351939A/en not_active Expired - Lifetime
1981
- 1981-04-27 ZA ZA00812759A patent/ZA812759B/xx unknown
- 1981-04-28 YU YU1103/81A patent/YU42565B/xx unknown
- 1981-04-30 NZ NZ196974A patent/NZ196974A/en unknown
- 1981-05-06 GR GR64860A patent/GR74687B/el unknown
- 1981-05-07 ES ES501994A patent/ES501994A0/es active Granted
- 1981-05-08 AU AU70292/81A patent/AU524822B2/en not_active Expired
- 1981-05-27 JP JP7944381A patent/JPS5724384A/ja active Granted
- 1981-07-01 GB GB8120338A patent/GB2085436B/en not_active Expired
- 1981-07-01 CY CY1325A patent/CY1325A/xx unknown
- 1981-08-11 CA CA000383588A patent/CA1175832A/en not_active Expired
- 1981-09-25 BE BE0/206077A patent/BE890509A/fr not_active IP Right Cessation
- 1981-09-28 LU LU83657A patent/LU83657A1/fr unknown
- 1981-09-30 DK DK433781A patent/DK148481C/da active
- 1981-10-12 FR FR8119153A patent/FR2492383A1/fr active Granted
- 1981-10-12 OA OA57515A patent/OA06920A/xx unknown
- 1981-10-13 FI FI813178A patent/FI75159C/fi not_active IP Right Cessation
- 1981-10-13 NL NLAANVRAGE8104660,A patent/NL179055C/xx not_active IP Right Cessation
- 1981-10-13 IT IT49476/81A patent/IT1143244B/it active
- 1981-10-13 SE SE8106060A patent/SE439167B/sv not_active IP Right Cessation
- 1981-10-14 CH CH6580/81A patent/CH647778A5/de not_active IP Right Cessation
- 1981-10-14 IL IL64047A patent/IL64047A/xx not_active IP Right Cessation
- 1981-10-15 IE IE2420/81A patent/IE51646B1/en not_active IP Right Cessation
- 1981-10-15 PT PT73824A patent/PT73824B/pt unknown
- 1981-10-15 HU HU843458A patent/HU187999B/hu unknown
- 1981-10-15 HU HU812982A patent/HU185967B/hu not_active IP Right Cessation
- 1981-10-16 DE DE3141256A patent/DE3141256C2/de not_active Expired
- 1981-10-16 AT AT0444681A patent/AT382153B/de not_active IP Right Cessation
- 1981-10-16 KR KR1019810003924D patent/KR890000465B1/ko active
- 1981-10-16 KR KR8103924A patent/KR870000321B1/ko not_active IP Right Cessation
1982
- 1982-04-01 ES ES511079A patent/ES511079A0/es active Granted
1983
- 1983-03-09 SU SU833562184A patent/SU1342420A3/ru active
- 1983-06-21 YU YU1360/83A patent/YU43316B/xx unknown
1985
- 1985-05-17 NL NL8501430A patent/NL8501430A/nl active Search and Examination
- 1985-12-17 JP JP60282152A patent/JPS61178983A/ja active Granted
- 1985-12-23 SG SG978/85A patent/SG97885G/en unknown
1986
- 1986-01-13 KE KE3596A patent/KE3596A/xx unknown
- 1986-01-15 SE SE8600174A patent/SE447257B/sv not_active IP Right Cessation
- 1986-05-22 HK HK353/86A patent/HK35386A/xx not_active IP Right Cessation
- 1986-12-30 MY MY475/86A patent/MY8600475A/xx unknown

Also Published As

Publication number	Publication date
HU187999B (en)	1986-03-28
IE51646B1 (en)	1987-01-21
AU524822B2 (en)	1982-10-07
NL179055B (nl)	1986-02-03
FI75159B (fi)	1988-01-29
JPS61178983A (ja)	1986-08-11
KR890000465B1 (ko)	1989-03-18
SE8600174D0 (sv)	1986-01-15
AT382153B (de)	1987-01-26
YU110381A (en)	1983-12-31
DK148481C (da)	1985-12-16
ATA444681A (de)	1986-06-15
IT1143244B (it)	1986-10-22
HK35386A (en)	1986-05-30
ES8304967A1 (es)	1983-03-16
LU83657A1 (fr)	1982-04-14
OA06920A (fr)	1983-05-31
CH647778A5 (de)	1985-02-15
MY8600475A (en)	1986-12-31
ES8206516A1 (es)	1982-08-16
ES511079A0 (es)	1983-03-16
SE447257B (sv)	1986-11-03
GB2085436B (en)	1984-01-18
NL179055C (nl)	1986-07-01
DE3141256A1 (de)	1982-08-19
FR2492383B1 (it)	1985-01-25
FI813178L (fi)	1982-04-17
DK433781A (da)	1982-04-17
GR74687B (it)	1984-07-03
NL8104660A (nl)	1982-05-17
ZA812759B (en)	1982-05-26
HU185967B (en)	1985-04-28
US4351939A (en)	1982-09-28
IL64047A (en)	1984-12-31
DE3141256C2 (de)	1986-06-05
SU1342420A3 (ru)	1987-09-30
YU43316B (en)	1989-06-30
NZ196974A (en)	1983-05-31
SG97885G (en)	1986-07-25
FI75159C (fi)	1988-05-09
AU7029281A (en)	1982-04-22
YU42565B (en)	1988-10-31
PT73824B (en)	1983-10-31
ES501994A0 (es)	1982-08-16
SE8106060L (sv)	1982-04-17
CY1325A (en)	1986-06-27
DK148481B (da)	1985-07-15
YU136083A (en)	1986-02-28
KR870000321B1 (en)	1987-02-27
JPS634828B2 (it)	1988-02-01
KE3596A (en)	1986-02-07
NL8501430A (nl)	1985-09-02
IE812420L (en)	1982-04-16
KR830007659A (ko)	1983-11-04
JPS6153353B2 (it)	1986-11-17
JPS5724384A (en)	1982-02-08
CA1175832A (en)	1984-10-09
GB2085436A (en)	1982-04-28
BE890509A (fr)	1982-03-25
FR2492383A1 (fr)	1982-04-23
PT73824A (en)	1981-11-01
SE439167B (sv)	1985-06-03
SE8600174L (sv)	1986-01-15
IL64047A0 (en)	1982-01-31

Legal Events

Date	Code	Title	Description
1999-10-27	TA	Fee payment date (situation as of event date), data collected since 19931001	Effective date: 19971030

Publication	Publication Date	Title
IT8149476A0 (it)	1981-10-13	Procedimento per la produzione di alogenuri ammonici spiroquaternari e prodotti ottenuti
IT1081128B (it)	1985-05-16	Procedimento per la produzione di prodotti zeolitici
IT8409482A0 (it)	1984-08-17	Procedimento per la produzione di oligonucleotidi
IT7927895A0 (it)	1979-12-07	Metodo e apparecchiatura per laproduzione di cuscini di sedile e prodotti con cio' ottenuti.
IT1139423B (it)	1986-09-24	Prodotti cementizi formati
IT1171331B (it)	1987-06-10	Procedimento continuo per la produzione di triclorosilano
IT1183879B (it)	1987-10-22	Procedimento per la produzione di prodotti alimentari con ripieno
IT1147322B (it)	1986-11-19	Procedimento per la fabbricazione di prodotti rivestiti con poliuretani
IT1138676B (it)	1986-09-17	Procedimento per la produzione di oggetti sagomati
IT1144744B (it)	1986-10-29	Procedimento per la produzione di solfobetaine
IT1209875B (it)	1989-08-30	Procedimento per la produzione di 2-metilenaldeidi
IT8440108A0 (it)	1984-11-28	Metodo per ottenere prodotti vernicianti eterocromatici e prodotti relativi
IT1190177B (it)	1988-02-16	Metodo per la produzione di materiali-fibrosi-non tessuti,elasticizzati e relativi prodotti
IT1180206B (it)	1987-09-23	Procedimento per la produzione di s-adenosil-l-omocisteina idrolasi
IT1195329B (it)	1988-10-12	Procedimento per la produzione di enzimi semisintetici e prodotto ottenuto
IT1141030B (it)	1986-10-01	Procedimento per la produzione di urea
IT1170845B (it)	1987-06-03	Procedimento per la produzione di derivati ciclopropanici tetra-sostiuiti e prodotti originali ottenuti
IT7947685A0 (it)	1979-01-17	Procedimento per la produzione di 2-pirrolidone e prodotto ottenuto
IT8147863A0 (it)	1981-02-20	Procedimento per la produzione di o-trimetil-sililcellulose
IT1166341B (it)	1987-04-29	Procedimento per la produzione di prodotti caseari
IT1157973B (it)	1987-02-18	Metodo per la preparazione di prodotti per spuntini
IT7948762A0 (it)	1979-04-18	Procedimento per la produzione di n-benzilamminoacidi contenuti zolfo e prodotto ottenuto
IT1155452B (it)	1987-01-28	Procedimento per la decorazione di un specchio e prodotti che ne risultano
IT1117196B (it)	1986-02-17	Procedimento per la produzione di amminoantrachinone e prodotto ottenuto
IT1134301B (it)	1986-08-13	Processo per la preparazione di 1-aza-2-idrossi benzantroni sostituiti e relativi prodotti ottenuti