IT1307281B1 - Uso di ubichinone q10 per il trattamento locale e la prevenzione dipatalogie oftalmologiche secondarie alla terapia fotorefrattiva, - Google Patents

Uso di ubichinone q10 per il trattamento locale e la prevenzione dipatalogie oftalmologiche secondarie alla terapia fotorefrattiva,

Info

Publication number
IT1307281B1
IT1307281B1 IT1999RM000719A ITRM990719A IT1307281B1 IT 1307281 B1 IT1307281 B1 IT 1307281B1 IT 1999RM000719 A IT1999RM000719 A IT 1999RM000719A IT RM990719 A ITRM990719 A IT RM990719A IT 1307281 B1 IT1307281 B1 IT 1307281B1
Authority
IT
Italy
Prior art keywords
prevention
dypatalogies
ubichinone
ophthalmological
local treatment
Prior art date
Application number
IT1999RM000719A
Other languages
English (en)
Inventor
Rosario Brancato
Sergio Capaccioli
Marco Fabrizio Saettone
Nicola Schiavone
Original Assignee
Simonelli Giuseppe
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Simonelli Giuseppe filed Critical Simonelli Giuseppe
Publication of ITRM990719A0 publication Critical patent/ITRM990719A0/it
Priority to IT1999RM000719A priority Critical patent/IT1307281B1/it
Priority to ES00974804T priority patent/ES2208434T3/es
Priority to AU13010/01A priority patent/AU1301001A/en
Priority to AT00974804T priority patent/ATE251905T1/de
Priority to DE60005992T priority patent/DE60005992T2/de
Priority to EP00974804A priority patent/EP1231909B1/en
Priority to PCT/IT2000/000434 priority patent/WO2001037851A2/en
Publication of ITRM990719A1 publication Critical patent/ITRM990719A1/it
Priority to US09/901,320 priority patent/US6787572B2/en
Application granted granted Critical
Publication of IT1307281B1 publication Critical patent/IT1307281B1/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355—Tocopherols, e.g. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Materials For Medical Uses (AREA)
  • External Artificial Organs (AREA)
  • Radiation-Therapy Devices (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
IT1999RM000719A 1999-11-25 1999-11-25 Uso di ubichinone q10 per il trattamento locale e la prevenzione dipatalogie oftalmologiche secondarie alla terapia fotorefrattiva, IT1307281B1 (it)

Priority Applications (8)

Application Number Priority Date Filing Date Title
IT1999RM000719A IT1307281B1 (it) 1999-11-25 1999-11-25 Uso di ubichinone q10 per il trattamento locale e la prevenzione dipatalogie oftalmologiche secondarie alla terapia fotorefrattiva,
DE60005992T DE60005992T2 (de) 1999-11-25 2000-10-30 Verwendung von ubiquinon q 10 zur vorbeugung und behandlung von postoperativen okularen pathologien
AU13010/01A AU1301001A (en) 1999-11-25 2000-10-30 Use of ubiquinone q10 for a local treatment and prevention of ophthalmologic pathologies following photorefractive therapy, refractive surgery and exposure to ultraviolet radiation
AT00974804T ATE251905T1 (de) 1999-11-25 2000-10-30 Verwendung von ubiquinon q 10 zur vorbeugung und behandlung von postoperativen okularen pathologien
ES00974804T ES2208434T3 (es) 1999-11-25 2000-10-30 Uso de la ubiquinona q10 para un tratamiento local y para la prevencion de las patologias oftamologicas posquirurgicas.
EP00974804A EP1231909B1 (en) 1999-11-25 2000-10-30 Use of ubiquinone q10 for the local treatment and prevention of post-surgical ophthalmologic pathologies
PCT/IT2000/000434 WO2001037851A2 (en) 1999-11-25 2000-10-30 Use of ubiquinone q10 for the local treatment and prevention of post-surgical ophthalmologic pathologies
US09/901,320 US6787572B2 (en) 1999-11-25 2001-07-09 Use of ubiquinone Q10 for the local treatment and prevention of post-surgical ophthalmologic pathologies

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT1999RM000719A IT1307281B1 (it) 1999-11-25 1999-11-25 Uso di ubichinone q10 per il trattamento locale e la prevenzione dipatalogie oftalmologiche secondarie alla terapia fotorefrattiva,

Publications (3)

Publication Number Publication Date
ITRM990719A0 ITRM990719A0 (it) 1999-11-25
ITRM990719A1 ITRM990719A1 (it) 2001-05-25
IT1307281B1 true IT1307281B1 (it) 2001-10-30

Family

ID=11407065

Family Applications (1)

Application Number Title Priority Date Filing Date
IT1999RM000719A IT1307281B1 (it) 1999-11-25 1999-11-25 Uso di ubichinone q10 per il trattamento locale e la prevenzione dipatalogie oftalmologiche secondarie alla terapia fotorefrattiva,

Country Status (8)

Country Link
US (1) US6787572B2 (it)
EP (1) EP1231909B1 (it)
AT (1) ATE251905T1 (it)
AU (1) AU1301001A (it)
DE (1) DE60005992T2 (it)
ES (1) ES2208434T3 (it)
IT (1) IT1307281B1 (it)
WO (1) WO2001037851A2 (it)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITRM20010755A1 (it) 2001-12-20 2003-06-20 Simonelli Giuseppe Uso del chinone q10 per il trattamento delle malattie oculari.
ES2276906T3 (es) * 2002-06-10 2007-07-01 D.M.G. Italia Srl Solucion oftalmica que contiene carboxi metilo beta-1,3 glucano.
ITRM20030153A1 (it) 2003-04-03 2004-10-04 Exall S R L Formulazione idrosolubile contenente ubichinone per uso oftalmico.
PL1904044T3 (pl) * 2005-07-08 2013-08-30 Sigma Tau Ind Farmaceuti Zastosowanie kombinacji obejmującej L- karnitynę lub alkanoilo-L-karnitynę, rozpuszczalny w tłuszczach benzochinon oraz wielonienasycony kwas tłuszczowy omega-3 do wytwarzania suplementu diety lub leku do leczenia chorób rogówki
US10583098B2 (en) * 2006-05-02 2020-03-10 Sung Lan Hsia Topical co-enzyme Q10 formulations and treatment of pain, fatigue and wounds
KR101690817B1 (ko) * 2009-06-30 2016-12-28 라이온 가부시키가이샤 안과용 조성물
EP2459186B1 (en) * 2009-07-27 2013-10-09 Salvatore Troisi Ophthalmic solution for protecting internal structures of the eyeball against uv-a rays or for the treatment of keratoconus with a trans-epithelial cross-linking technique
ITVA20100044A1 (it) * 2010-05-20 2011-11-21 Ciro Caruso Soluzione oftalmica per proteggere strutture interne del globo oculare da raggi uv-a o per il trattamento del cheratocono con tecnica di cross-linking trans-epiteliale
US11419830B2 (en) 2017-05-17 2022-08-23 Berg Llc Use of coenzyme Q10 formulations in the treatment and prevention of epidermolysis bullosa

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5947202A (ja) * 1982-09-10 1984-03-16 Zeria Shinyaku Kogyo Kk 補酵素Ｑ↓１↓０のメチル化−β−シクロデキストリン包接体及びその製造方法
DE4410238A1 (de) * 1994-03-25 1995-09-28 Beiersdorf Ag Hautpflegemittel
AU719671B2 (en) * 1995-06-07 2000-05-18 Howard Foundation, The Pharmaceutically active carotenoids
EP1279401B1 (en) * 1997-09-05 2008-01-09 GlaxoSmithKline Biologicals S.A. Oil in water emulsions containing saponins
IT1304406B1 (it) * 1998-10-21 2001-03-19 Danital Italia S R L Preparazione per la veicolazione di principi attivi basata su acidigrassi polinsaturi del gruppo omega 3.
WO2000057871A2 (en) * 1999-03-30 2000-10-05 Purdue Research Foundation Methods for identifying agents that inhibit serum aging factors and uses and compositions thereof

Also Published As

Publication number Publication date
DE60005992D1 (de) 2003-11-20
EP1231909B1 (en) 2003-10-15
WO2001037851A2 (en) 2001-05-31
EP1231909A2 (en) 2002-08-21
DE60005992T2 (de) 2004-07-22
AU1301001A (en) 2001-06-04
ES2208434T3 (es) 2004-06-16
ITRM990719A1 (it) 2001-05-25
US20030236239A1 (en) 2003-12-25
WO2001037851A3 (en) 2002-03-21
US6787572B2 (en) 2004-09-07
ITRM990719A0 (it) 1999-11-25
ATE251905T1 (de) 2003-11-15

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