IT1274175B - Procedimento per la preparazione di una combinazione chimica farmacologicamente attiva - Google Patents
Procedimento per la preparazione di una combinazione chimica farmacologicamente attivaInfo
- Publication number
- IT1274175B IT1274175B ITMI942362A ITMI942362A IT1274175B IT 1274175 B IT1274175 B IT 1274175B IT MI942362 A ITMI942362 A IT MI942362A IT MI942362 A ITMI942362 A IT MI942362A IT 1274175 B IT1274175 B IT 1274175B
- Authority
- IT
- Italy
- Prior art keywords
- procedure
- preparation
- pharmacologically active
- chemical combination
- active chemical
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/18—Sulfonamides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/55—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound the modifying agent being also a pharmacologically or therapeutically active agent, i.e. the entire conjugate being a codrug, i.e. a dimer, oligomer or polymer of pharmacologically or therapeutically active compounds
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Procedimento per la preparazione di una combinazione chimica farmacologicamente attiva costituita dall'associazione, mediante legami chimici, di unità uguali tra loro, ciascuna unità risultando dotata di attività farmacologica propria, avente formula generale:M-A-X-B-M (I)dove M indica detta unità dotata di attività farmacologica propria, X indica una struttura "bidentata" atta ad interconnettere le unità M, A e B indicano gruppi funzionali uguali o diversi tra loro che consentono la interconnessione tra M ed X.
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI942362A IT1274175B (it) | 1994-11-22 | 1994-11-22 | Procedimento per la preparazione di una combinazione chimica farmacologicamente attiva |
PCT/EP1995/004556 WO1996015809A2 (en) | 1994-11-22 | 1995-11-20 | Process for the preparation of a pharmacologically active chemical combination |
EP95940211A EP0793507A2 (en) | 1994-11-22 | 1995-11-20 | Process for the preparation of a pharmacologically active chemical combination |
EP00105715A EP1038534A3 (en) | 1994-11-22 | 1995-11-20 | Process for the preparation of a conjugate of pharmacologically active substances |
US08/836,756 US6369260B1 (en) | 1994-11-22 | 1995-11-20 | Process for the preparation of a pharmacologically active chemical combination |
AU41741/96A AU4174196A (en) | 1994-11-22 | 1995-11-20 | Process for the preparation of a pharmacologically active chemical combination |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI942362A IT1274175B (it) | 1994-11-22 | 1994-11-22 | Procedimento per la preparazione di una combinazione chimica farmacologicamente attiva |
Publications (3)
Publication Number | Publication Date |
---|---|
ITMI942362A0 ITMI942362A0 (it) | 1994-11-22 |
ITMI942362A1 ITMI942362A1 (it) | 1996-05-22 |
IT1274175B true IT1274175B (it) | 1997-07-15 |
Family
ID=11369887
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ITMI942362A IT1274175B (it) | 1994-11-22 | 1994-11-22 | Procedimento per la preparazione di una combinazione chimica farmacologicamente attiva |
Country Status (5)
Country | Link |
---|---|
US (1) | US6369260B1 (it) |
EP (2) | EP1038534A3 (it) |
AU (1) | AU4174196A (it) |
IT (1) | IT1274175B (it) |
WO (1) | WO1996015809A2 (it) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1246621A4 (en) * | 1999-12-23 | 2004-11-24 | Nitromed Inc | NITROSED AND NITROSYLATED CYCLOOXYGENASE-2 INHIBITORS, COMPOSITIONS AND METHODS FOR THEIR USE |
AU2002360555A1 (en) * | 2001-12-10 | 2003-06-23 | Control Delivery Systems Inc. | Treatment of genitourinary tract disorders |
EP1539134A4 (en) | 2002-06-11 | 2007-04-11 | Nitromed Inc | SELECTIVE INHIBITORS OF CYCLOOXIGENASE-2 NITROSIS AND / OR NITROSYLES, COMPOSITIONS AND METHODS OF USE |
CA2493156A1 (en) * | 2002-07-29 | 2004-02-05 | Nitromed, Inc. | Cyclooxygenase-2 selective inhibitors, compositions and methods of use |
WO2005009480A2 (en) * | 2003-06-11 | 2005-02-03 | Control Delivery Systems, Inc. | Implants containing codrugs |
US20070112050A1 (en) * | 2005-04-12 | 2007-05-17 | Psivida Inc. | HMGCoA reductase inhibitor combinations and uses thereof |
JP2009503075A (ja) * | 2005-08-01 | 2009-01-29 | シヴィダ・インコーポレイテッド | HMGCoA還元酵素インヒビターコドラッグ及びその使用 |
JP2007275193A (ja) * | 2006-04-04 | 2007-10-25 | Fujifilm Corp | 光プローブおよび光断層画像化装置 |
GB2470187A (en) * | 2009-05-11 | 2010-11-17 | Pharmapatents Global Ltd | Captopril polymers |
CN110668947B (zh) * | 2019-10-14 | 2021-05-18 | 新乡海盈生物科技有限责任公司 | 一种邻羟基苯甲酸聚二醇酯类化合物及其合成制备方法和医药用途 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB872130A (en) | 1959-06-22 | 1961-07-05 | Christian Jean Marie Warolin | Improvements in and relating to a process for preparing acetylsalicyclic acid anhydride |
US3025215A (en) | 1959-07-29 | 1962-03-13 | Monsanto Chemicals | Bis (8-quinolyl carbonate) derivatives |
CH428766A (de) | 1963-01-17 | 1967-01-31 | Yoshitomi Pharmaceutical | Verfahren zur Herstellung eines Esters der Acetylsalicylsäure mit einem mehrwertigen Alkohol |
DE1768345B2 (de) | 1968-05-03 | 1976-12-02 | Hoechst Ag, 6000 Frankfurt | Dimere steroid-21-alkylcarbonate und verfahren zu ihrer herstellung |
CH583562A5 (it) | 1973-07-17 | 1977-01-14 | Bracco Ind Chimica Spa | |
LU78106A1 (de) * | 1977-05-11 | 1979-05-23 | Ciba Geigy Ag | Verfahren zur herstellung neuer substituierter phenylessigsaeureamidverbindungen |
IL67445A (en) * | 1982-12-09 | 1985-11-29 | Teva Pharma | Ethoxycarbonyloxy ethyl esters of non-steroidal anti-inflammatory carboxylic acids |
DK8502611A (it) * | 1985-08-08 | 1986-12-12 | ||
DK406686D0 (da) * | 1986-08-26 | 1986-08-26 | Hans Bundgaard | Carboxylsyrederivater |
AU655762B2 (en) * | 1989-12-26 | 1995-01-12 | Nova Pharmaceutical Corporation | Prodrug anhydrides of asprin, indomethacin and ibuprofen, their preparation, compositions, and anti-inflammatory method of use |
-
1994
- 1994-11-22 IT ITMI942362A patent/IT1274175B/it active IP Right Grant
-
1995
- 1995-11-20 AU AU41741/96A patent/AU4174196A/en not_active Abandoned
- 1995-11-20 EP EP00105715A patent/EP1038534A3/en not_active Withdrawn
- 1995-11-20 EP EP95940211A patent/EP0793507A2/en not_active Withdrawn
- 1995-11-20 US US08/836,756 patent/US6369260B1/en not_active Expired - Fee Related
- 1995-11-20 WO PCT/EP1995/004556 patent/WO1996015809A2/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO1996015809A2 (en) | 1996-05-30 |
WO1996015809A3 (en) | 1996-10-17 |
ITMI942362A0 (it) | 1994-11-22 |
EP1038534A3 (en) | 2001-04-04 |
US6369260B1 (en) | 2002-04-09 |
EP0793507A2 (en) | 1997-09-10 |
ITMI942362A1 (it) | 1996-05-22 |
AU4174196A (en) | 1996-06-17 |
EP1038534A2 (en) | 2000-09-27 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES2175066T3 (es) | Antagonistas triciclicos de la vasopresina. | |
SI0769967T1 (sl) | Konjugati vsebujoäśi protitumorna sredstva in njihova uporaba | |
RS50485B (sr) | Terapeutske kombinacije koje sadrže amplodipin i atorvastatin | |
NO903762D0 (no) | Fremgangsmaate for aa opprette diffusjonsbinding mellom korrosjonsbestandige materialer. | |
IT1274175B (it) | Procedimento per la preparazione di una combinazione chimica farmacologicamente attiva | |
NO903926D0 (no) | Aktive limsammensetninger. | |
TR200000272T2 (tr) | Antitümör ve antimetastaz maddeleri olarak o-ikameli hidrosikumaranon türevleri. | |
CA2320706A1 (en) | 20-hete antagonists and agonists | |
DE69625230D1 (de) | Thrombininhibitoren | |
IT1299616B1 (it) | Unita' modulare di manipolazione | |
DE68912252D1 (de) | Imidazolantiarrythmische Mittel. | |
USD444182S1 (en) | Set of heximoes | |
RU93049257A (ru) | Изобутилзамещенные метансульфонил-хинолилметоксифенилциклоалкилуксусной кислоты | |
KR900700481A (ko) | 1,4-치환된-2,3.5,6-테트라하이드로 [1,3,6]트리아조시노[1,2,-a] 벤즈이미다졸 및 이의 중간체 | |
FR2757360B1 (fr) | Dispositif modulaire d'agencement, notamment du type gondole | |
ITMI931806A0 (it) | Composti inibitpri di acil enzima-a-colesterolo-o-acil transferasi ad attivita' terapeutica , loro uso e composizioni farmaceutiche che li contengono | |
IT1229230B (it) | Piperidinilimidazopiridine farmacologicamente attive. | |
DE59206745D1 (de) | Aktive Frequenzweiche | |
IT1299865B1 (it) | Unita' per la formazione di pile di articoli. | |
ITRM930264A0 (it) | Principi attivi anti-infiammatori non steroidei senza effetti di perossidazione sulle membrane biologiche. | |
IT1274023B (it) | Derivati della purina ad attivita' farmacologica, loro uso e composizioni farmaceutiche che li contengono | |
IT222985Z2 (it) | Elemento modulare, componibile, particolarmente adatto per la realizzazione di pedane, di pavimenti sopraelevati, di scaffali e d'altre strutture d'arredamento. | |
ITBO940421A0 (it) | Unita' modulare per il contenimento di fiale, fialoidi e similari. | |
IT1280958B1 (it) | Zatterone di salvataggio marittimo in molteplice applicabilita'. | |
IT9047918A0 (it) | 2 bromo 6beta metilpregna 1,4 diene 3,20 dioni, procedimento per la loro preparazione e composizioni farmaceutiche ad attivita' anti infiammatoria che li contengono. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
0001 | Granted | ||
TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19971028 |