IT1248543B - DRUG DISPENSING SYSTEM TO ADMINISTER GROWTH FACTORS. - Google Patents

DRUG DISPENSING SYSTEM TO ADMINISTER GROWTH FACTORS.

Info

Publication number
IT1248543B
IT1248543B ITMI911741A ITMI911741A IT1248543B IT 1248543 B IT1248543 B IT 1248543B IT MI911741 A ITMI911741 A IT MI911741A IT MI911741 A ITMI911741 A IT MI911741A IT 1248543 B IT1248543 B IT 1248543B
Authority
IT
Italy
Prior art keywords
growth factors
dispensing system
drug dispensing
administer growth
administer
Prior art date
Application number
ITMI911741A
Other languages
Italian (it)
Inventor
Ponti Roberto De
Clara Torricelli
Carlo Confalonieri
Marco Adami
Alessandro Martini
Ercole Lardini
Original Assignee
Erba Carlo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Carlo Spa filed Critical Erba Carlo Spa
Publication of ITMI911741A0 publication Critical patent/ITMI911741A0/en
Publication of ITMI911741A1 publication Critical patent/ITMI911741A1/en
Application granted granted Critical
Publication of IT1248543B publication Critical patent/IT1248543B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0057—Ingredients of undetermined constitution or reaction products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0023—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0028—Polypeptides; Proteins; Degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/50—Fibroblast growth factor [FGF]
    • C07K14/503—Fibroblast growth factor [FGF] basic FGF [bFGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Materials Engineering (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Abstract

Una polvere comprendente microsfere di polisaccaridi insolubili in acqua e rigonfiabili con acqua, caricate con un fattore di crescita in grado di legarsi a eparina, come un fattore di crescita basico a base di fibroblasti, è utile per applicazioni a ferite e ustioni.A powder comprising water-insoluble and water-swellable polysaccharide microspheres, loaded with a growth factor capable of binding to heparin, as a basic growth factor based on fibroblasts, is useful for wound and burn applications.

ITMI911741A 1990-07-05 1991-06-25 DRUG DISPENSING SYSTEM TO ADMINISTER GROWTH FACTORS. IT1248543B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909014871A GB9014871D0 (en) 1990-07-05 1990-07-05 Drug delivery system for administering growth factor

Publications (3)

Publication Number Publication Date
ITMI911741A0 ITMI911741A0 (en) 1991-06-25
ITMI911741A1 ITMI911741A1 (en) 1992-12-25
IT1248543B true IT1248543B (en) 1995-01-19

Family

ID=10678678

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI911741A IT1248543B (en) 1990-07-05 1991-06-25 DRUG DISPENSING SYSTEM TO ADMINISTER GROWTH FACTORS.

Country Status (4)

Country Link
JP (1) JPH04279530A (en)
DE (1) DE4121891A1 (en)
GB (2) GB9014871D0 (en)
IT (1) IT1248543B (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5352589A (en) * 1988-09-16 1994-10-04 Farmitalia Carlo Erba S.R.L. Deletion mutant of basic fibroblast growth factor and production thereof
AU1052492A (en) * 1991-01-31 1992-08-06 Farmitalia Carlo Erba S.R.L. Synergistic composition comprising a fibroblast growth factor and a sulfated polylsaccharide, for use as antiviral agent
JP3639593B2 (en) 1993-05-31 2005-04-20 科研製薬株式会社 Cross-linked gelatin gel preparation containing basic fibroblast growth factor
AUPM572294A0 (en) * 1994-05-18 1994-06-09 Vaccine Technologies Pty. Ltd. Delivery vehicle for bioactive molecule
EP0914168A1 (en) * 1996-05-03 1999-05-12 Innogenetics N.V. New medicaments containing gelatin cross-linked with oxidized polysaccharides
ATE298562T1 (en) * 1999-02-03 2005-07-15 Powderject Res Ltd HYDROGEL PARTICLE FORMULATIONS
JP4565691B2 (en) * 2000-02-28 2010-10-20 株式会社Ｐｈｇ Sustained release substrate for heparin-binding growth factor and heparin-binding growth factor sustained-release agent
KR100720056B1 (en) * 2005-10-06 2007-05-18 (주) 차바이오텍 A Method for producing microsphere coated with nanoparticle containing growth factor and the using method for neuronal differentiation thereby
CN101143894A (en) * 2007-06-22 2008-03-19 中国药科大学 Highly effective polypeptide for inhibiting angiogenesis, physical chemistry modifying method and application thereof
ES2784192T3 (en) * 2011-03-04 2020-09-23 Inst Nat Sante Rech Med Particles that contain a growth factor and their uses
TW201932124A (en) * 2018-01-18 2019-08-16 近鎰生技股份有限公司 Hemostatic material, preparation method thereof and pharmaceutical composition containing the same

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ235556A (en) * 1986-11-05 1991-06-25 Ethicon Inc Breast milk substitute containing recombinant human egf
NZ226171A (en) * 1987-09-18 1990-06-26 Ethicon Inc Gel formulation containing polypeptide growth factor
NZ226170A (en) * 1987-09-18 1990-07-26 Ethicon Inc Stable freeze-dried pharmaceutical composition containing epidermal growth factor

Also Published As

Publication number Publication date
JPH04279530A (en) 1992-10-05
ITMI911741A0 (en) 1991-06-25
DE4121891A1 (en) 1992-01-09
GB9114493D0 (en) 1991-08-21
ITMI911741A1 (en) 1992-12-25
GB2245831A (en) 1992-01-15
GB2245831B (en) 1994-03-23
GB9014871D0 (en) 1990-08-22

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970619