GB2245831B - Drug delivery system for administering growth factors - Google Patents

Drug delivery system for administering growth factors

Info

Publication number
GB2245831B
GB2245831B GB9114493A GB9114493A GB2245831B GB 2245831 B GB2245831 B GB 2245831B GB 9114493 A GB9114493 A GB 9114493A GB 9114493 A GB9114493 A GB 9114493A GB 2245831 B GB2245831 B GB 2245831B
Authority
GB
United Kingdom
Prior art keywords
delivery system
drug delivery
growth factors
administering growth
administering
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
GB9114493A
Other versions
GB9114493D0 (en
GB2245831A (en
Inventor
Ponti Roberto De
Clara Torricelli
Carlo Confalonieri
Marco Adami
Alessandro Martini
Ercole Lardini
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmitalia Carlo Erba SRL
Carlo Erba SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmitalia Carlo Erba SRL, Carlo Erba SpA filed Critical Farmitalia Carlo Erba SRL
Publication of GB9114493D0 publication Critical patent/GB9114493D0/en
Publication of GB2245831A publication Critical patent/GB2245831A/en
Application granted granted Critical
Publication of GB2245831B publication Critical patent/GB2245831B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0057—Ingredients of undetermined constitution or reaction products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0023—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0028—Polypeptides; Proteins; Degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/50—Fibroblast growth factor [FGF]
    • C07K14/503—Fibroblast growth factor [FGF] basic FGF [bFGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Materials Engineering (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Toxicology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
GB9114493A 1990-07-05 1991-07-04 Drug delivery system for administering growth factors Expired - Fee Related GB2245831B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909014871A GB9014871D0 (en) 1990-07-05 1990-07-05 Drug delivery system for administering growth factor

Publications (3)

Publication Number Publication Date
GB9114493D0 GB9114493D0 (en) 1991-08-21
GB2245831A GB2245831A (en) 1992-01-15
GB2245831B true GB2245831B (en) 1994-03-23

Family

ID=10678678

Family Applications (2)

Application Number Title Priority Date Filing Date
GB909014871A Pending GB9014871D0 (en) 1990-07-05 1990-07-05 Drug delivery system for administering growth factor
GB9114493A Expired - Fee Related GB2245831B (en) 1990-07-05 1991-07-04 Drug delivery system for administering growth factors

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GB909014871A Pending GB9014871D0 (en) 1990-07-05 1990-07-05 Drug delivery system for administering growth factor

Country Status (4)

Country Link
JP (1) JPH04279530A (en)
DE (1) DE4121891A1 (en)
GB (2) GB9014871D0 (en)
IT (1) IT1248543B (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5352589A (en) * 1988-09-16 1994-10-04 Farmitalia Carlo Erba S.R.L. Deletion mutant of basic fibroblast growth factor and production thereof
AU1052492A (en) * 1991-01-31 1992-08-06 Farmitalia Carlo Erba S.R.L. Synergistic composition comprising a fibroblast growth factor and a sulfated polylsaccharide, for use as antiviral agent
JP3639593B2 (en) 1993-05-31 2005-04-20 科研製薬株式会社 Cross-linked gelatin gel preparation containing basic fibroblast growth factor
AUPM572294A0 (en) * 1994-05-18 1994-06-09 Vaccine Technologies Pty. Ltd. Delivery vehicle for bioactive molecule
EP0914168A1 (en) * 1996-05-03 1999-05-12 Innogenetics N.V. New medicaments containing gelatin cross-linked with oxidized polysaccharides
ATE298562T1 (en) * 1999-02-03 2005-07-15 Powderject Res Ltd HYDROGEL PARTICLE FORMULATIONS
JP4565691B2 (en) * 2000-02-28 2010-10-20 株式会社Ｐｈｇ Sustained release substrate for heparin-binding growth factor and heparin-binding growth factor sustained-release agent
KR100720056B1 (en) * 2005-10-06 2007-05-18 (주) 차바이오텍 A Method for producing microsphere coated with nanoparticle containing growth factor and the using method for neuronal differentiation thereby
CN101143894A (en) * 2007-06-22 2008-03-19 中国药科大学 Highly effective polypeptide for inhibiting angiogenesis, physical chemistry modifying method and application thereof
ES2784192T3 (en) * 2011-03-04 2020-09-23 Inst Nat Sante Rech Med Particles that contain a growth factor and their uses
TW201932124A (en) * 2018-01-18 2019-08-16 近鎰生技股份有限公司 Hemostatic material, preparation method thereof and pharmaceutical composition containing the same

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0267015A2 (en) * 1986-11-05 1988-05-11 Ethicon, Inc. Stabilized compositions containing epidermal growth factor
EP0308238A1 (en) * 1987-09-18 1989-03-22 Ethicon, Inc. Stable lyophilized formulations containing growth factors
EP0312208A1 (en) * 1987-09-18 1989-04-19 Ethicon, Inc. Gel formulations containing growth factors

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0267015A2 (en) * 1986-11-05 1988-05-11 Ethicon, Inc. Stabilized compositions containing epidermal growth factor
EP0308238A1 (en) * 1987-09-18 1989-03-22 Ethicon, Inc. Stable lyophilized formulations containing growth factors
EP0312208A1 (en) * 1987-09-18 1989-04-19 Ethicon, Inc. Gel formulations containing growth factors

Also Published As

Publication number Publication date
JPH04279530A (en) 1992-10-05
IT1248543B (en) 1995-01-19
ITMI911741A0 (en) 1991-06-25
DE4121891A1 (en) 1992-01-09
GB9114493D0 (en) 1991-08-21
ITMI911741A1 (en) 1992-12-25
GB2245831A (en) 1992-01-15
GB9014871D0 (en) 1990-08-22

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 20000704