IT1235166B - Peptidi contenenti silicio, loro preparazione e loro impiego come medicamenti - Google Patents

Peptidi contenenti silicio, loro preparazione e loro impiego come medicamenti

Info

Publication number
IT1235166B
IT1235166B IT8848638A IT4863888A IT1235166B IT 1235166 B IT1235166 B IT 1235166B IT 8848638 A IT8848638 A IT 8848638A IT 4863888 A IT4863888 A IT 4863888A IT 1235166 B IT1235166 B IT 1235166B
Authority
IT
Italy
Prior art keywords
medications
preparation
containing silicon
peptides containing
peptides
Prior art date
Application number
IT8848638A
Other languages
English (en)
Italian (it)
Other versions
IT8848638A0 (it
Inventor
Weidmann Beat
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of IT8848638A0 publication Critical patent/IT8848638A0/it
Application granted granted Critical
Publication of IT1235166B publication Critical patent/IT1235166B/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0227Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the (partial) peptide sequence -Phe-His-NH-(X)2-C(=0)-, e.g. Renin-inhibitors with n = 2 - 6; for n > 6 see C07K5/06 - C07K5/10
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/0803Compounds with Si-C or Si-Si linkages
    • C07F7/081Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/0803Compounds with Si-C or Si-Si linkages
    • C07F7/081Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
    • C07F7/0812Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0205Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)3-C(=0)-, e.g. statine or derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IT8848638A 1987-12-15 1988-12-13 Peptidi contenenti silicio, loro preparazione e loro impiego come medicamenti IT1235166B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3742474 1987-12-15

Publications (2)

Publication Number Publication Date
IT8848638A0 IT8848638A0 (it) 1988-12-13
IT1235166B true IT1235166B (it) 1992-06-22

Family

ID=6342652

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8848638A IT1235166B (it) 1987-12-15 1988-12-13 Peptidi contenenti silicio, loro preparazione e loro impiego come medicamenti

Country Status (5)

Country Link
JP (1) JPH01199983A (de)
CH (1) CH677877A5 (de)
FR (1) FR2624513A1 (de)
GB (1) GB2212158A (de)
IT (1) IT1235166B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5220047A (en) * 1990-09-17 1993-06-15 Union Carbide Chemicals & Plastics Technology Corporation Carbamate silicon compounds as latent coupling agents and process for preparation and use
US5559140A (en) * 1991-01-02 1996-09-24 Merrell Pharmaceuticals Inc. Difluoro statone analogs
HU210647B (en) * 1991-01-02 1995-06-28 Merrell Dow Pharma Process for producing antiviral difluoro-statone derivatives and pharmaceutical compositions containing them
ES2152982T3 (es) * 1993-07-08 2001-02-16 Merrell Pharma Inc Analogos de la difluoroestatona.
EP0717731B1 (de) * 1993-09-09 1999-04-21 Merrell Pharmaceuticals Inc. Antivirale analoge von difluorostaton
US6114380A (en) * 1995-12-18 2000-09-05 Merrell Pharmaceuticals Inc. Difluoro statone analogs
EP2261662B1 (de) 2009-06-10 2014-01-22 Forschungszentrum Borstel Leibniz-Zentrum für Medizin und Biowissenschaften Neuartige synthetische Blockierlösungen

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0316965A3 (de) * 1983-02-07 1989-08-09 Aktiebolaget Hässle Enzym-Inhibitoren

Also Published As

Publication number Publication date
CH677877A5 (de) 1991-07-15
IT8848638A0 (it) 1988-12-13
JPH01199983A (ja) 1989-08-11
GB8828982D0 (en) 1989-01-25
FR2624513A1 (fr) 1989-06-16
GB2212158A (en) 1989-07-19

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