IT1229569B - Derivati di acidi biliari, loro preparazione e composizioni farmaceutiche che li contengono. - Google Patents

Derivati di acidi biliari, loro preparazione e composizioni farmaceutiche che li contengono.

Info

Publication number
IT1229569B
IT1229569B IT8920169A IT2016989A IT1229569B IT 1229569 B IT1229569 B IT 1229569B IT 8920169 A IT8920169 A IT 8920169A IT 2016989 A IT2016989 A IT 2016989A IT 1229569 B IT1229569 B IT 1229569B
Authority
IT
Italy
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
acid derivatives
biliary acid
Prior art date
Application number
IT8920169A
Other languages
English (en)
Other versions
IT8920169A0 (it
Inventor
Roberto Pellicciari
Aldo Roda
Giuliano Frigerio
Original Assignee
Giuliani Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Giuliani Spa filed Critical Giuliani Spa
Publication of IT8920169A0 publication Critical patent/IT8920169A0/it
Priority to IT8920169A priority Critical patent/IT1229569B/it
Priority to US07/507,260 priority patent/US5057509A/en
Priority to ES90106972T priority patent/ES2074492T3/es
Priority to DE69020781T priority patent/DE69020781T2/de
Priority to AT90106972T priority patent/ATE124953T1/de
Priority to JP2096160A priority patent/JP2816589B2/ja
Priority to DK90106972.4T priority patent/DK0393494T3/da
Priority to EP90106972A priority patent/EP0393494B1/en
Priority to CA002014544A priority patent/CA2014544C/en
Application granted granted Critical
Publication of IT1229569B publication Critical patent/IT1229569B/it
Priority to US07/761,441 priority patent/US5166374A/en
Priority to GR950402753T priority patent/GR3017640T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
IT8920169A 1989-04-17 1989-04-17 Derivati di acidi biliari, loro preparazione e composizioni farmaceutiche che li contengono. IT1229569B (it)

Priority Applications (11)

Application Number Priority Date Filing Date Title
IT8920169A IT1229569B (it) 1989-04-17 1989-04-17 Derivati di acidi biliari, loro preparazione e composizioni farmaceutiche che li contengono.
US07/507,260 US5057509A (en) 1989-04-17 1990-04-09 Bile acid derivatives, processes for the preparation thereof and pharmaceutical compositions containing them
AT90106972T ATE124953T1 (de) 1989-04-17 1990-04-11 Gallensäure-derivate, verfahren zu deren herstellung und pharmazeutische zusammensetzungen daraus.
DE69020781T DE69020781T2 (de) 1989-04-17 1990-04-11 Gallensäure-Derivate, Verfahren zu deren Herstellung und pharmazeutische Zusammensetzungen daraus.
ES90106972T ES2074492T3 (es) 1989-04-17 1990-04-11 Derivados de acidos biliares, procedimiento para su preparacion y composiciones farmaceuticas que los contienen.
JP2096160A JP2816589B2 (ja) 1989-04-17 1990-04-11 胆汁酸誘導体、その製造方法ならびにそれらを含有する製薬組成物
DK90106972.4T DK0393494T3 (da) 1989-04-17 1990-04-11 Galdesyrederivater, fremgangsmåde til fremstilling deraf og farmaceutiske midler indeholdende disse
EP90106972A EP0393494B1 (en) 1989-04-17 1990-04-11 Bile acid derivatives, processes for the preparation thereof and pharmaceutical compositions containing them
CA002014544A CA2014544C (en) 1989-04-17 1990-04-12 Bile acid derivatives, processes for the preparation thereof and pharmaceutical compositions containing them
US07/761,441 US5166374A (en) 1989-04-17 1991-09-18 Bile acid derivatives, processes for the preparation thereof and pharmaceutical compositions containing them
GR950402753T GR3017640T3 (en) 1989-04-17 1995-10-04 Bile acid derivatives, processes for the preparation thereof and pharmaceutical compositions containing them.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8920169A IT1229569B (it) 1989-04-17 1989-04-17 Derivati di acidi biliari, loro preparazione e composizioni farmaceutiche che li contengono.

Publications (2)

Publication Number Publication Date
IT8920169A0 IT8920169A0 (it) 1989-04-17
IT1229569B true IT1229569B (it) 1991-09-04

Family

ID=11164375

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8920169A IT1229569B (it) 1989-04-17 1989-04-17 Derivati di acidi biliari, loro preparazione e composizioni farmaceutiche che li contengono.

Country Status (10)

Country Link
US (1) US5057509A (it)
EP (1) EP0393494B1 (it)
JP (1) JP2816589B2 (it)
AT (1) ATE124953T1 (it)
CA (1) CA2014544C (it)
DE (1) DE69020781T2 (it)
DK (1) DK0393494T3 (it)
ES (1) ES2074492T3 (it)
GR (1) GR3017640T3 (it)
IT (1) IT1229569B (it)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5166374A (en) * 1989-04-17 1992-11-24 Giuliani S.P.A. Bile acid derivatives, processes for the preparation thereof and pharmaceutical compositions containing them
JP3546886B2 (ja) * 1993-03-10 2004-07-28 ジェネーラ コーポレーション ステロイド誘導体、それらを含む薬剤組成物、及び抗生物質又は消毒薬としてのそれらの使用
US5856535A (en) * 1994-08-18 1999-01-05 Magainin Pharmaceuticals, Inc. Aminosterol ester compounds
US5840740A (en) * 1995-06-07 1998-11-24 Magainin Pharmaceuticals Inc. Aminosterol compounds and a method of treating infection using the aminosterol compounds
US5795885A (en) * 1995-06-07 1998-08-18 Magainin Pharmaceuticals Inc. Method of inhibiting profileration of cells by administering an aminosterol compound
US5840936A (en) * 1995-06-07 1998-11-24 Magainin Pharmaceuticals Inc. Aminosterol compounds useful as inhibitors of the sodium/proton exchanger (NHE)
US5847172A (en) * 1995-06-07 1998-12-08 Magainin Pharmaceuticals Inc. Certain aminosterol compounds and pharmaceutical compositions including these compounds
US5874597A (en) * 1995-06-07 1999-02-23 Magainin Pharmaceuticals, Inc. Certain aminosterol compounds and pharmaceutical compositions including these compounds
US5763430A (en) * 1995-06-07 1998-06-09 Magainin Pharmaceuticals Inc. Method of treating a viral infection by administering a steroid compound
US5994336A (en) * 1995-06-07 1999-11-30 Magainin Pharmaceuticals Inc. Method of inhibiting proliferation of cells by administering an aminosterol compound
US6143738A (en) * 1995-06-07 2000-11-07 Magainin Pharmaceuticals, Inc. Therapeutic uses for an aminosterol compound
US5792635A (en) * 1995-06-07 1998-08-11 Magainin Pharmaceuticals, Inc. Method of inhibiting the sodium/proton exchanger NHE3 and method of inhibiting growth by administering squalamine
JP2000510460A (ja) * 1996-04-26 2000-08-15 マゲイニン・ファーマシューティカルズ・インコーポレーテッド スクアラミンを他の抗癌剤と併用する上皮性悪性腫瘍の治療
US6596712B2 (en) 1996-04-26 2003-07-22 Genaera Corporation Treatment of carcinomas using squalamine in combination with other anti-cancer agents or modalities
US6262283B1 (en) 1996-12-06 2001-07-17 Magainin Pharmaceuticals Inc. Stereoselective synthesis of 24-hydroxylated compounds useful for the preparation of aminosterols, vitamin D analogs, and other compounds
AU5342701A (en) * 2000-04-12 2001-10-30 Genaera Corp A process for the preparation of 7.alpha.-hydroxy 3-aminosubstituted sterols using intermediates with an unprotected 7.alpha.-hydroxy group
HUE030010T2 (en) * 2005-05-12 2017-04-28 Medizinische Universität Graz 24-norUDCA for the treatment of autoimmune hepatitis
US20110268775A1 (en) 2009-01-06 2011-11-03 Pharmanova, Inc. Nanoparticle pharmaceutical formulations

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1152801B (it) * 1982-08-17 1987-01-14 Proter Spa Composti steroidei ad attivita' coleretica, processo per la loro preparazione e composizioni terapeutiche che li contengono come principio attivo
JPS5955844A (ja) * 1982-09-23 1984-03-31 ピ−ピ−ジ−　インダストリ−ズ　インコ−ポレ−テツド 高障害性フエノ−ル類またはそれらの塩と炭酸エステルとからエ−テルを製造する方法
FR2534735B1 (fr) * 1982-10-15 1985-07-05 Habia Sa Revetement isolant
US4560774A (en) * 1982-11-17 1985-12-24 Arizona State University Macrocyclic lactones
US4539908A (en) * 1982-12-27 1985-09-10 Electronova S.A. Printing unit with an electrostatic printing aid comprising electrodes contained in a lid structure
IT1223313B (it) * 1987-10-20 1990-09-19 Gipharmex Spa Derivati di acidi biliari loro preparazione e composizioni farmaceutiche che li contengono

Also Published As

Publication number Publication date
US5057509A (en) 1991-10-15
DK0393494T3 (da) 1995-11-20
JP2816589B2 (ja) 1998-10-27
CA2014544A1 (en) 1990-10-17
CA2014544C (en) 2001-06-12
EP0393494A2 (en) 1990-10-24
ATE124953T1 (de) 1995-07-15
EP0393494B1 (en) 1995-07-12
ES2074492T3 (es) 1995-09-16
EP0393494A3 (en) 1992-05-20
DE69020781D1 (de) 1995-08-17
JPH02292299A (ja) 1990-12-03
GR3017640T3 (en) 1996-01-31
DE69020781T2 (de) 1995-11-30
IT8920169A0 (it) 1989-04-17

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Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19960424