IT1112581B - ISOKINOLINE DERIVATIVES, THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM - Google Patents

ISOKINOLINE DERIVATIVES, THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Info

Publication number
IT1112581B
IT1112581B IT22150/79A IT2215079A IT1112581B IT 1112581 B IT1112581 B IT 1112581B IT 22150/79 A IT22150/79 A IT 22150/79A IT 2215079 A IT2215079 A IT 2215079A IT 1112581 B IT1112581 B IT 1112581B
Authority
IT
Italy
Prior art keywords
isokinoline
derivatives
preparation
pharmaceutical compositions
compositions containing
Prior art date
Application number
IT22150/79A
Other languages
Italian (it)
Other versions
IT7922150A0 (en
Original Assignee
Rhone Poulenc Ind
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR7812026A external-priority patent/FR2424270A1/en
Priority claimed from FR7904004A external-priority patent/FR2449087A2/en
Application filed by Rhone Poulenc Ind filed Critical Rhone Poulenc Ind
Publication of IT7922150A0 publication Critical patent/IT7922150A0/en
Application granted granted Critical
Publication of IT1112581B publication Critical patent/IT1112581B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • C07D217/16Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IT22150/79A 1978-04-24 1979-04-24 ISOKINOLINE DERIVATIVES, THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM IT1112581B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7812026A FR2424270A1 (en) 1978-04-24 1978-04-24 4,5-Di:hydro-2-imidazolyl-amino-isoquinoline derivs. - useful as antihypertensives having low toxicity and free from sedative side effects
FR7904004A FR2449087A2 (en) 1979-02-16 1979-02-16 4,5-Di:hydro-2-imidazolyl-amino-isoquinoline derivs. - useful as antihypertensives having low toxicity and free from sedative side effects

Publications (2)

Publication Number Publication Date
IT7922150A0 IT7922150A0 (en) 1979-04-24
IT1112581B true IT1112581B (en) 1986-01-20

Family

ID=26220560

Family Applications (1)

Application Number Title Priority Date Filing Date
IT22150/79A IT1112581B (en) 1978-04-24 1979-04-24 ISOKINOLINE DERIVATIVES, THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Country Status (10)

Country Link
AU (1) AU4621979A (en)
DE (1) DE2916577A1 (en)
DK (1) DK166979A (en)
ES (2) ES479878A1 (en)
GB (1) GB2020280B (en)
IT (1) IT1112581B (en)
LU (1) LU81182A1 (en)
NL (1) NL7902993A (en)
NZ (1) NZ190245A (en)
SE (1) SE7903554L (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW397812B (en) * 1995-02-11 2000-07-11 Astra Ab Bicyclic isothiourea derivatives useful in therapy
US7217722B2 (en) * 2000-02-01 2007-05-15 Kirin Beer Kabushiki Kaisha Nitrogen-containing compounds having kinase inhibitory activity and drugs containing the same
US7074805B2 (en) * 2002-02-20 2006-07-11 Abbott Laboratories Fused azabicyclic compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor
US6933311B2 (en) 2003-02-11 2005-08-23 Abbott Laboratories Fused azabicyclic compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor
US7767705B2 (en) 2006-08-25 2010-08-03 Abbott Laboratories Compounds that inhibit TRPV1 and uses thereof
EP2450346A1 (en) 2006-12-20 2012-05-09 Abbott Laboratories Antagonists of the TRPV1 receptor and uses thereof
JP2011515414A (en) 2008-03-20 2011-05-19 アボット・ラボラトリーズ Methods of making central nervous system drugs that are TRPV1 antagonists

Also Published As

Publication number Publication date
GB2020280A (en) 1979-11-14
DE2916577A1 (en) 1979-10-31
DK166979A (en) 1979-10-25
NL7902993A (en) 1979-10-26
AU4621979A (en) 1979-11-01
LU81182A1 (en) 1979-11-07
ES482070A1 (en) 1980-04-01
GB2020280B (en) 1982-07-28
NZ190245A (en) 1981-03-16
IT7922150A0 (en) 1979-04-24
ES479878A1 (en) 1980-08-16
SE7903554L (en) 1979-10-25

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