IT1054620B - Poli(idrossimetilene)idroinsolubile biologicamente attivo procedimento per la sua preparazione e suo impiego nella cromatografia per affinita - Google Patents
Poli(idrossimetilene)idroinsolubile biologicamente attivo procedimento per la sua preparazione e suo impiego nella cromatografia per affinitaInfo
- Publication number
- IT1054620B IT1054620B IT22967/75A IT2296775A IT1054620B IT 1054620 B IT1054620 B IT 1054620B IT 22967/75 A IT22967/75 A IT 22967/75A IT 2296775 A IT2296775 A IT 2296775A IT 1054620 B IT1054620 B IT 1054620B
- Authority
- IT
- Italy
- Prior art keywords
- poli
- hydroxymethylene
- affinity
- chromatography
- procedure
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Clostridium (G)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/76—Albumins
- C07K14/765—Serum albumin, e.g. HSA
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F8/00—Chemical modification by after-treatment
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
- C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
- C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
- C12N11/082—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
- C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
- C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
- C12N11/089—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6429—Thrombin (3.4.21.5)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01018—Exo-alpha-sialidase (3.2.1.18), i.e. trans-sialidase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21005—Thrombin (3.4.21.5)
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Toxicology (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Analytical Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
- Polyesters Or Polycarbonates (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19742421789 DE2421789C3 (de) | 1974-05-06 | Biologisch aktive Produkte und Verfahren zu ihrer Herstellung |
Publications (1)
Publication Number | Publication Date |
---|---|
IT1054620B true IT1054620B (it) | 1981-11-30 |
Family
ID=5914739
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT22967/75A IT1054620B (it) | 1974-05-06 | 1975-05-02 | Poli(idrossimetilene)idroinsolubile biologicamente attivo procedimento per la sua preparazione e suo impiego nella cromatografia per affinita |
Country Status (16)
Country | Link |
---|---|
JP (1) | JPS599153B2 (nl) |
AT (1) | AT338417B (nl) |
BE (1) | BE828776A (nl) |
CA (1) | CA1063049A (nl) |
CH (1) | CH630410A5 (nl) |
DK (1) | DK196175A (nl) |
ES (1) | ES437153A1 (nl) |
FI (1) | FI60216C (nl) |
FR (1) | FR2270266B1 (nl) |
GB (1) | GB1512651A (nl) |
IE (1) | IE41040B1 (nl) |
IT (1) | IT1054620B (nl) |
LU (1) | LU72407A1 (nl) |
NL (1) | NL181782C (nl) |
NO (1) | NO144672C (nl) |
SE (2) | SE427086B (nl) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2552510C3 (de) * | 1975-11-22 | 1981-02-19 | Behringwerke Ag, 3550 Marburg | Biologisch aktive Verbindungen und Verfahren zu ihrer Herstellung |
AU2003219796A1 (en) * | 2002-02-20 | 2003-09-09 | Beth Israel Deaconess Medical Center | Conjugates comprising a biodegradable polymer and uses therefor |
JP6476934B2 (ja) * | 2015-02-02 | 2019-03-06 | 東ソー株式会社 | 新規重合体、およびそれを有する細胞培養基材 |
-
1975
- 1975-04-29 ES ES437153A patent/ES437153A1/es not_active Expired
- 1975-04-30 FI FI751299A patent/FI60216C/fi not_active IP Right Cessation
- 1975-05-01 NL NLAANVRAGE7505152,A patent/NL181782C/nl not_active IP Right Cessation
- 1975-05-02 CA CA226,193A patent/CA1063049A/en not_active Expired
- 1975-05-02 IT IT22967/75A patent/IT1054620B/it active
- 1975-05-05 DK DK196175A patent/DK196175A/da not_active Application Discontinuation
- 1975-05-05 AT AT342275A patent/AT338417B/de not_active IP Right Cessation
- 1975-05-05 CH CH575075A patent/CH630410A5/de not_active IP Right Cessation
- 1975-05-05 IE IE996/75A patent/IE41040B1/xx unknown
- 1975-05-05 LU LU72407A patent/LU72407A1/xx unknown
- 1975-05-05 NO NO751599A patent/NO144672C/no unknown
- 1975-05-05 GB GB18761/75A patent/GB1512651A/en not_active Expired
- 1975-05-06 JP JP50054436A patent/JPS599153B2/ja not_active Expired
- 1975-05-06 BE BE156099A patent/BE828776A/xx not_active IP Right Cessation
- 1975-05-06 FR FR7514177A patent/FR2270266B1/fr not_active Expired
- 1975-05-06 SE SE7505275A patent/SE427086B/xx not_active IP Right Cessation
-
1978
- 1978-05-16 SE SE7805544A patent/SE444947B/sv not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
FR2270266A1 (nl) | 1975-12-05 |
FI60216C (fi) | 1981-12-10 |
DE2421789A1 (de) | 1975-11-13 |
FI751299A (nl) | 1975-11-07 |
DK196175A (da) | 1975-11-07 |
FI60216B (fi) | 1981-08-31 |
NO751599L (nl) | 1975-11-07 |
NO144672C (no) | 1981-10-14 |
BE828776A (fr) | 1975-11-06 |
ES437153A1 (es) | 1977-04-16 |
NL7505152A (nl) | 1975-11-10 |
IE41040B1 (en) | 1979-10-10 |
AT338417B (de) | 1977-08-25 |
NL181782B (nl) | 1987-06-01 |
NL181782C (nl) | 1987-11-02 |
SE7505275L (sv) | 1975-11-07 |
SE427086B (sv) | 1983-03-07 |
JPS599153B2 (ja) | 1984-02-29 |
SE444947B (sv) | 1986-05-20 |
CH630410A5 (en) | 1982-06-15 |
AU8081875A (en) | 1976-11-11 |
DE2421789B2 (de) | 1976-10-07 |
JPS50155679A (nl) | 1975-12-16 |
CA1063049A (en) | 1979-09-25 |
NO144672B (no) | 1981-07-06 |
GB1512651A (en) | 1978-06-01 |
ATA342275A (de) | 1976-12-15 |
LU72407A1 (nl) | 1977-02-09 |
IE41040L (en) | 1975-11-06 |
FR2270266B1 (nl) | 1979-03-16 |
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