IN2015DN03854A - - Google Patents

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Publication number
IN2015DN03854A
IN2015DN03854A IN3854DEN2015A IN2015DN03854A IN 2015DN03854 A IN2015DN03854 A IN 2015DN03854A IN 3854DEN2015 A IN3854DEN2015 A IN 3854DEN2015A IN 2015DN03854 A IN2015DN03854 A IN 2015DN03854A
Authority
IN
India
Prior art keywords
methods
formula
administering
relates
present
Prior art date
Application number
Other languages
English (en)
Inventor
James Wallace Sleigh
William Alexander Denny
Jiney Jose
Swarnalatha Akuratiya Gamage
Martyn Gregory Harvey
Logan James Voss
Original Assignee
Auckland Uniservices Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Auckland Uniservices Ltd filed Critical Auckland Uniservices Ltd
Publication of IN2015DN03854A publication Critical patent/IN2015DN03854A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/10—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
    • C07C229/14—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of carbon skeletons containing rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
    • C07C225/20—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/46—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
IN3854DEN2015 2012-10-08 2013-10-08 IN2015DN03854A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
NZ60288512 2012-10-08
NZ61120213 2013-05-28
PCT/IB2013/059191 WO2014057414A1 (en) 2012-10-08 2013-10-08 Ketamine derivatives

Publications (1)

Publication Number Publication Date
IN2015DN03854A true IN2015DN03854A (zh) 2015-10-02

Family

ID=50476991

Family Applications (1)

Application Number Title Priority Date Filing Date
IN3854DEN2015 IN2015DN03854A (zh) 2012-10-08 2013-10-08

Country Status (13)

Country Link
US (3) US20150259277A1 (zh)
EP (1) EP2903963A4 (zh)
JP (2) JP6309957B2 (zh)
KR (1) KR20150065873A (zh)
CN (1) CN104837810B (zh)
AU (1) AU2013328280B2 (zh)
BR (1) BR112015007647A2 (zh)
CA (1) CA2922340A1 (zh)
EA (1) EA201590697A1 (zh)
HK (1) HK1212673A1 (zh)
IN (1) IN2015DN03854A (zh)
MX (1) MX2015004362A (zh)
WO (1) WO2014057414A1 (zh)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20150065873A (ko) * 2012-10-08 2015-06-15 오클랜드 유니서비시즈 리미티드 케타민 유도체
US20160332962A1 (en) * 2015-05-13 2016-11-17 Janssen Pharmaceutica Nv (s)-csa salt of s-ketamine, (r)-csa salt of s-ketamine and processes for the preparation of s-ketamine
AU2016288188B2 (en) 2015-06-27 2021-08-05 Shenox Pharmaceuticals, Llc Ketamine transdermal delivery system
US11827606B2 (en) 2015-11-18 2023-11-28 Spirify Pharma Inc. Phenyl cyclohexanone derivatives and methods of making and using them
WO2017087388A1 (en) * 2015-11-18 2017-05-26 Mitchell Woods Pharmaceuticals, Inc. Phenyl cyclohexanone derivatives and methods of making and using them
US10919842B2 (en) * 2016-03-25 2021-02-16 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Crystal forms and methods of synthesis of (2R, 6R)-hydroxynorketamine and (2S, 6S)-hydroxynorketamine
WO2019137381A1 (en) 2018-01-10 2019-07-18 Xw Laboratories, Inc. Prodrugs of ketamine, compositions and uses thereof
WO2019186357A1 (en) * 2018-03-26 2019-10-03 Cellix Bio Private Limited Compositions and methods for the treatment of neurological diseases
EP3802480B1 (en) * 2018-06-04 2023-08-02 The United States of America, as represented by the Secretary, Department of Health and Human Services Process for synthesis and purification of (2r,6r)-hydroxynorketamine
CN112125816A (zh) * 2020-03-17 2020-12-25 国药集团工业有限公司 一种***、其衍生物或其盐的消旋化方法
WO2023018966A1 (en) 2021-08-13 2023-02-16 XWPharma Ltd. Pharmaceutical compositions and oral dosage forms of ketamine derivatives
CN115677444A (zh) * 2022-10-26 2023-02-03 公安部第三研究所 同位素毒品代谢物标记化合物及其制备方法、用途

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3254124A (en) 1962-06-29 1966-05-31 Parke Davis & Co Aminoketones and methods for their production
GB1134146A (en) * 1967-09-15 1968-11-20 Parke Davis & Co New organic amines and methods for their production
US5019583A (en) 1989-02-15 1991-05-28 Glaxo Inc. N-phenyl-N-(4-piperidinyl)amides useful as analgesics
US5466700A (en) 1993-08-30 1995-11-14 Glaxo Wellcome Inc. Anesthetic use of N-phenyl-N-(4-piperidinyl)amides
US5866591A (en) 1996-09-11 1999-02-02 Glaxo Wellcome Inc. Stable formulations of remifentanil
EP1272463A1 (en) * 2000-01-28 2003-01-08 Rohm And Haas Company Enhanced propertied pharmaceuticals
US20040248963A1 (en) 2001-11-23 2004-12-09 Bueno Melendo Ana Belen Prodrugs of excitatory amino acids
ATE492565T1 (de) 2002-01-31 2011-01-15 Randox Lab Ltd Immunogene, antikörper und konjugate für ketamin und dessen metaboliten
AU2003291037A1 (en) * 2002-11-18 2004-06-15 Yaupon Therapeutics, Inc. Analgesic uses of norketamine and ketamine/norketamine prodrugs
EA017264B1 (ru) 2005-09-28 2012-11-30 Аурис Медикаль Аг Применение композиции арилциклоалкиламида для получения лекарственного препарата для лечения нарушения внутреннего уха
WO2008134525A1 (en) 2007-04-26 2008-11-06 Auspex Pharmaeuticals, Inc. Deuterium labelled ketamine
EP2766339B1 (en) 2011-10-14 2021-06-09 The United States Of America, as represented by the Secretary, Department of Health & Human Services The use of (2r, 6r)-hydroxynorketamine and other stereoisomeric hydroxylated metabolites of (r,s)- ketamine in the treatment of depression and neuropathic pain
KR20150065873A (ko) * 2012-10-08 2015-06-15 오클랜드 유니서비시즈 리미티드 케타민 유도체

Also Published As

Publication number Publication date
CN104837810A (zh) 2015-08-12
MX2015004362A (es) 2015-12-08
US10239825B2 (en) 2019-03-26
JP2018127466A (ja) 2018-08-16
US20190169113A1 (en) 2019-06-06
EP2903963A1 (en) 2015-08-12
JP2015535847A (ja) 2015-12-17
WO2014057414A1 (en) 2014-04-17
KR20150065873A (ko) 2015-06-15
HK1212673A1 (zh) 2016-06-17
US20150259277A1 (en) 2015-09-17
CA2922340A1 (en) 2014-04-17
AU2013328280A1 (en) 2015-05-14
JP6309957B2 (ja) 2018-04-11
CN104837810B (zh) 2019-08-06
EP2903963A4 (en) 2016-05-25
EA201590697A1 (ru) 2015-09-30
AU2013328280B2 (en) 2017-12-21
US20170190653A1 (en) 2017-07-06
BR112015007647A2 (pt) 2017-07-04
WO2014057414A9 (en) 2014-12-18

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