IN2014MN00976A - - Google Patents

Info

Publication number
IN2014MN00976A
IN2014MN00976A IN976MUN2014A IN2014MN00976A IN 2014MN00976 A IN2014MN00976 A IN 2014MN00976A IN 976MUN2014 A IN976MUN2014 A IN 976MUN2014A IN 2014MN00976 A IN2014MN00976 A IN 2014MN00976A
Authority
IN
India
Prior art keywords
amine
alcohol
solvent
reaction
preparation
Prior art date
Application number
Inventor
Marc Poirot
Michaël PAILLASSE
Medina Philippe De
Sandrine Poirot
Original Assignee
Inserm Inst Nat De La Santé Et De La Rech Médicale
Affichem
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inserm Inst Nat De La Santé Et De La Rech Médicale, Affichem filed Critical Inserm Inst Nat De La Santé Et De La Rech Médicale
Publication of IN2014MN00976A publication Critical patent/IN2014MN00976A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J43/00Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005Oxygen-containing hetero ring
    • C07J71/001Oxiranes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

The present invention relates to a process for the preparation of sterol derivatives comprising the reaction of an a epoxy compound with an amine in an alcohol comprising 3 to 5 carbon atoms as a solvent.
IN976MUN2014 2011-11-24 2012-11-23 IN2014MN00976A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP11306548 2011-11-24
PCT/EP2012/073489 WO2013076257A1 (en) 2011-11-24 2012-11-23 Process for the preparation of sterol derivatives

Publications (1)

Publication Number Publication Date
IN2014MN00976A true IN2014MN00976A (en) 2015-04-24

Family

ID=47216329

Family Applications (1)

Application Number Title Priority Date Filing Date
IN976MUN2014 IN2014MN00976A (en) 2011-11-24 2012-11-23

Country Status (14)

Country Link
US (1) US9447141B2 (en)
EP (1) EP2782923B1 (en)
JP (1) JP6157492B2 (en)
KR (1) KR20140098131A (en)
CN (1) CN104039807B (en)
AU (1) AU2012342460B2 (en)
BR (1) BR112014012458A2 (en)
CA (1) CA2856609C (en)
ES (1) ES2613753T3 (en)
IN (1) IN2014MN00976A (en)
MX (1) MX343787B (en)
RU (1) RU2014125435A (en)
WO (1) WO2013076257A1 (en)
ZA (1) ZA201403736B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3091970B1 (en) 2014-01-10 2020-10-28 Rgenix, Inc. Lxr agonists and uses thereof
CA3010883A1 (en) 2016-01-11 2017-07-20 The Rockefeller University Methods for the treatment of myeloid derived suppressor cells related disorders
FR3064470A1 (en) * 2017-03-31 2018-10-05 Lessonia MASK OR PATCH PREPARED FROM ALGINATE COMPOSITION
US11214536B2 (en) 2017-11-21 2022-01-04 Inspirna, Inc. Polymorphs and uses thereof
CA3112878A1 (en) * 2018-09-19 2020-03-26 Modernatx, Inc. Sterol purification
JP2023509845A (en) 2019-12-13 2023-03-10 インスピルナ,インコーポレーテッド Metal salt and its use
BE1028852B1 (en) 2020-12-03 2022-07-05 Dendrogenix 5α-Hydroxy-6β-[2-(1H-imidazol-4-yl)ethylamino]cholestan-3β-ol PRODRUG AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM FOR USE IN THE TREATMENT OF CANCER

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2838741B1 (en) 2002-04-19 2006-01-27 Inst Nat Sante Rech Med STEROL DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS COMPRISING THE SAME

Also Published As

Publication number Publication date
MX2014006303A (en) 2014-09-08
CN104039807B (en) 2018-02-13
EP2782923B1 (en) 2016-11-23
CA2856609A1 (en) 2013-05-30
ES2613753T3 (en) 2017-05-25
BR112014012458A2 (en) 2017-06-06
RU2014125435A (en) 2015-12-27
JP6157492B2 (en) 2017-07-05
US20140309417A1 (en) 2014-10-16
AU2012342460A1 (en) 2014-06-12
AU2012342460B2 (en) 2017-06-29
US9447141B2 (en) 2016-09-20
ZA201403736B (en) 2015-11-25
MX343787B (en) 2016-10-31
EP2782923A1 (en) 2014-10-01
JP2015502934A (en) 2015-01-29
CA2856609C (en) 2021-01-12
WO2013076257A1 (en) 2013-05-30
KR20140098131A (en) 2014-08-07
CN104039807A (en) 2014-09-10

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