IN2014KN01716A - - Google Patents

Info

Publication number
IN2014KN01716A
IN2014KN01716A IN1716KON2014A IN2014KN01716A IN 2014KN01716 A IN2014KN01716 A IN 2014KN01716A IN 1716KON2014 A IN1716KON2014 A IN 1716KON2014A IN 2014KN01716 A IN2014KN01716 A IN 2014KN01716A
Authority
IN
India
Prior art keywords
antibody
cancer
amino acid
acid sequence
seq
Prior art date
Application number
Inventor
Shinichi Kobayashi
Fumiyoshi Okano
Takanori Saito
Original Assignee
Toray Industries
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toray Industries filed Critical Toray Industries
Publication of IN2014KN01716A publication Critical patent/IN2014KN01716A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The present invention discloses an antibody that targets a cancer antigen protein expressed specifically on the surface of cancer cells and the application of the antibody in a treatment and/or preventative agent for said cancer. Specifically disclosed are: an antibody or a fragment thereof said antibody being immunologically reactive with a partial polypeptide of CAPRIN 1 comprising the amino acid sequence represented by SEQ ID NO: 5 or an amino acid sequence having 80% or more sequence identity to the amino acid sequence represented by SEQ ID NO: 5; and a pharmaceutical composition for the treatment and/or prevention of cancer said pharmaceutical composition being characterized by containing as an active ingredient the antibody or a fragment thereof.
IN1716KON2014 2012-02-21 2013-02-21 IN2014KN01716A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2012035491 2012-02-21
PCT/JP2013/054345 WO2013125640A1 (en) 2012-02-21 2013-02-21 Pharmaceutical composition for treatment and/or prevention of cancer

Publications (1)

Publication Number Publication Date
IN2014KN01716A true IN2014KN01716A (en) 2015-10-23

Family

ID=49005817

Family Applications (1)

Application Number Title Priority Date Filing Date
IN1716KON2014 IN2014KN01716A (en) 2012-02-21 2013-02-21

Country Status (17)

Country Link
US (1) US9266958B2 (en)
EP (1) EP2824114B1 (en)
JP (1) JP6187258B2 (en)
KR (1) KR102009236B1 (en)
CN (1) CN104114583B (en)
AU (1) AU2013223147B2 (en)
BR (1) BR112014021103A2 (en)
CA (1) CA2865020C (en)
DK (1) DK2824114T3 (en)
ES (1) ES2739380T3 (en)
HU (1) HUE045461T2 (en)
IN (1) IN2014KN01716A (en)
MX (1) MX360211B (en)
PL (1) PL2824114T3 (en)
PT (1) PT2824114T (en)
RU (1) RU2633505C2 (en)
WO (1) WO2013125640A1 (en)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT2322221E (en) 2008-08-05 2014-09-19 Toray Industries Pharmaceutical composition for treatment and prevention of cancer
HUE027332T2 (en) 2008-08-05 2016-09-28 Toray Industries Cancer detection method
PT2532743E (en) * 2010-02-04 2015-08-04 Toray Industries Pharmaceutical composition for treatment and/or prevention of cancer
JP6003650B2 (en) * 2011-08-04 2016-10-05 東レ株式会社 Pharmaceutical composition for treatment and / or prevention of pancreatic cancer
US9796775B2 (en) 2011-08-04 2017-10-24 Toray Industries, Inc. Method for detecting pancreatic cancer
CA2864869C (en) 2012-02-21 2021-10-19 Toray Industries, Inc. Pharmaceutical composition for treatment and/or prevention of cancer
JP6107655B2 (en) 2012-03-30 2017-04-05 東レ株式会社 Pharmaceutical composition for treatment and / or prevention of gallbladder cancer
PL2832365T3 (en) * 2012-03-30 2018-04-30 Toray Industries, Inc. Pharmaceutical composition for treatment and/or prevention of liver cancer
CN104471404B (en) 2012-07-19 2017-03-01 东丽株式会社 The detection method of cancer
HUE043162T2 (en) 2012-07-19 2019-08-28 Toray Industries Method for detecting cancer
JP6447130B2 (en) 2013-08-09 2019-01-09 東レ株式会社 Pharmaceutical composition for treatment and / or prevention of cancer
WO2018009916A1 (en) 2016-07-07 2018-01-11 The Board Of Trustees Of The Leland Stanford Junior University Antibody adjuvant conjugates
BR112019008335A2 (en) 2016-10-28 2020-01-28 Toray Industries conjugate of an antibody, pharmaceutical composition and method for the treatment and / or prevention of cancer
WO2019189780A1 (en) 2018-03-30 2019-10-03 東レ株式会社 Pharmaceutical composition for treatment and/or prevention of cancer
JP2022525594A (en) 2019-03-15 2022-05-18 ボルト バイオセラピューティクス、インコーポレーテッド Immune conjugates targeting HER2
AU2020291014A1 (en) 2019-06-13 2022-01-27 Bolt Biotherapeutics, Inc. Aminobenzazepine compounds, immunoconjugates, and uses thereof
US20220347310A1 (en) 2019-09-30 2022-11-03 Bolt Biotherapeutics, Inc. Amide-linked, aminobenzazepine immunoconjugates, and uses thereof
BR112022007719A2 (en) 2019-10-25 2022-07-12 Bolt Biotherapeutics Inc IMMUNOCONJUGATES, BINDING COMPOUND, PHARMACEUTICAL COMPOSITION, METHOD TO TREAT CANCER, USE OF AN IMMUNOCONJUGATE AND METHOD OF PREPARING AN IMMUNOCONJUGATE
BR112022018161A2 (en) 2020-03-12 2022-10-25 Toray Industries DRUG FOR THE TREATMENT AND/OR PREVENTION OF CANCER, AGENTS THAT INCREASE THE EFFICACY OF A DRUG AND METHOD FOR THE TREATMENT AND/OR PREVENTION OF CANCER
WO2021182573A1 (en) 2020-03-12 2021-09-16 東レ株式会社 Medicament for treatment and/or prevention of cancer
EP4119157A4 (en) 2020-03-12 2024-03-27 Toray Industries Medicament for treatment and/or prevention of cancer
WO2021182572A1 (en) 2020-03-12 2021-09-16 東レ株式会社 Medicament for treatment and/or prevention of cancer
KR20220152309A (en) 2020-03-12 2022-11-15 도레이 카부시키가이샤 Medicines for the treatment and/or prevention of cancer
EP4146282A1 (en) 2020-05-08 2023-03-15 Bolt Biotherapeutics, Inc. Elastase-substrate, peptide linker immunoconjugates, and uses thereof
KR20230051189A (en) 2020-08-13 2023-04-17 볼트 바이오테라퓨틱스 인코퍼레이티드 Pyrazolozepine Immunoconjugates and Uses Thereof
CA3225422A1 (en) 2021-06-23 2022-12-29 Toray Industries, Inc. Medicament for treatment and/or prevention of cancer
AU2022296193A1 (en) 2021-06-23 2024-01-18 Toray Industries, Inc. Medicament for treatment and/or prevention of cancer
CN117677398A (en) 2021-07-27 2024-03-08 东丽株式会社 Medicine for treating and/or preventing cancer
CN117693363A (en) 2021-07-27 2024-03-12 东丽株式会社 Medicine for treating and/or preventing cancer
WO2023008461A1 (en) 2021-07-27 2023-02-02 東レ株式会社 Medicament for treatment and/or prevention of cancer
JPWO2023033129A1 (en) 2021-09-03 2023-03-09
WO2023076599A1 (en) 2021-10-29 2023-05-04 Bolt Biotherapeutics, Inc. Tlr agonist immunoconjugates with cysteine-mutant antibodies, and uses thereof

Family Cites Families (72)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8607679D0 (en) 1986-03-27 1986-04-30 Winter G P Recombinant dna product
WO1996002576A1 (en) 1994-07-13 1996-02-01 Chugai Seiyaku Kabushiki Kaisha Reconstituted human antibody against human interleukin-8
US5698396A (en) 1995-06-07 1997-12-16 Ludwig Institute For Cancer Research Method for identifying auto-immunoreactive substances from a subject
FR2761994B1 (en) 1997-04-11 1999-06-18 Centre Nat Rech Scient PREPARATION OF MEMBRANE RECEPTORS FROM EXTRACELLULAR BACULOVIRUSES
US6677436B1 (en) 1998-04-03 2004-01-13 Chugai Seiyaku Kabushiki Kaisha Humanized antibody against human tissue factor (TF) and process of production of the humanized antibody
US20030118599A1 (en) 1999-04-02 2003-06-26 Corixa Corporation Compositions and methods for the therapy and diagnosis of lung cancer
RU2234942C2 (en) 1998-07-14 2004-08-27 Корикса Корпорейшн Tumor polypeptide isolated from prostate and polynucleotide encoding thereof
KR20010083111A (en) 1998-07-14 2001-08-31 길리스 스티브 Compositions and methods for therapy and diagnosis of prostate cancer
US6969518B2 (en) 1998-12-28 2005-11-29 Corixa Corporation Compositions and methods for the therapy and diagnosis of breast cancer
AU3316600A (en) 1999-02-22 2000-09-21 Torben F. Orntoft Gene expression in bladder tumors
US6444425B1 (en) 1999-04-02 2002-09-03 Corixa Corporation Compounds for therapy and diagnosis of lung cancer and methods for their use
EP1187915A2 (en) 1999-04-02 2002-03-20 Corixa Corporation Compounds for therapy and diagnosis of lung cancer and methods for their use
US6949245B1 (en) 1999-06-25 2005-09-27 Genentech, Inc. Humanized anti-ErbB2 antibodies and treatment with anti-ErbB2 antibodies
CA2388822A1 (en) 1999-10-29 2001-05-10 Human Genome Sciences, Inc. 27 human secreted proteins
US20020006404A1 (en) 1999-11-08 2002-01-17 Idec Pharmaceuticals Corporation Treatment of cell malignancies using combination of B cell depleting antibody and immune modulating antibody related applications
PL366626A1 (en) 2000-03-29 2005-02-07 Corixa Corporation Compositions and methods for the therapy and diagnosis of lung cancer
CA2430013C (en) 2000-11-30 2011-11-22 Medarex, Inc. Transgenic transchromosomal rodents for making human antibodies
US7919467B2 (en) 2000-12-04 2011-04-05 Immunotope, Inc. Cytotoxic T-lymphocyte-inducing immunogens for prevention, treatment, and diagnosis of cancer
US20040029114A1 (en) 2001-01-24 2004-02-12 Eos Technology, Inc. Methods of diagnosis of breast cancer, compositions and methods of screening for modulators of breast cancer
RU2306952C2 (en) 2001-01-31 2007-09-27 Байоджен Айдек Инк. Method for treating the cases of malignant tumors containing b-cells with a combination of applications related to antibodies reducing b-cells number and with immunomodulating antibodies
US20040236091A1 (en) 2001-03-28 2004-11-25 Chicz Roman M. Translational profiling
WO2002083070A2 (en) 2001-04-10 2002-10-24 Corixa Corporation Compounds for immunotherapy and diagnosis of colon cancer and methods for their use
WO2002092001A2 (en) 2001-05-11 2002-11-21 Corixa Corporation Compositions and methods for the therapy and diagnosis of lung cancer
DK1391511T3 (en) 2001-05-11 2008-09-29 Kirin Pharma Kk Human artificial chromosome containing human antibody lambda light chain gene
US20030190640A1 (en) 2001-05-31 2003-10-09 Mary Faris Genes expressed in prostate cancer
US20040142325A1 (en) 2001-09-14 2004-07-22 Liat Mintz Methods and systems for annotating biomolecular sequences
EP2388265A1 (en) 2002-02-22 2011-11-23 Genentech, Inc. Compositions and methods for the treatment of immune related diseases
US20050003390A1 (en) 2002-05-17 2005-01-06 Axenovich Sergey A. Targets for controlling cellular growth and for diagnostic methods
WO2004007668A2 (en) 2002-07-12 2004-01-22 The Regents Of The University Of California Improved transporters and their uses
US20040126379A1 (en) 2002-08-21 2004-07-01 Boehringer Ingelheim International Gmbh Compositions and methods for treating cancer using cytotoxic CD44 antibody immunoconjugates and chemotherapeutic agents
CA2504144A1 (en) 2002-11-26 2004-06-10 Genentech, Inc. Compositions and methods for the diagnosis of immune related diseases using pro7
WO2004097051A2 (en) 2003-04-29 2004-11-11 Wyeth Methods for diagnosing aml and mds differential gene expression
KR20060031809A (en) 2003-06-09 2006-04-13 더 리젠츠 오브 더 유니버시티 오브 미시간 Compositions and methods for treating and diagnosing cancer
WO2005007830A2 (en) 2003-07-14 2005-01-27 Mayo Foundation For Medical Education And Research Methods and compositions for diagnosis, staging and prognosis of prostate cancer
US20050032113A1 (en) 2003-07-17 2005-02-10 Mitsubishi Pharma Corporation Membrane protein library for proteome analysis and method for preparing same
JP2008506352A (en) 2004-01-26 2008-03-06 デビオビジョン・インコーポレーテッド Novel organism-specific polypeptides and uses thereof
PL1735348T3 (en) 2004-03-19 2012-11-30 Imclone Llc Human anti-epidermal growth factor receptor antibody
DK1730191T3 (en) 2004-03-30 2011-10-17 Glaxo Group Ltd Immunoglobulin Binding to HOSM
WO2005100998A2 (en) 2004-04-16 2005-10-27 Europroteome Ag Membrane markers for use in cancer diagnosis and therapy
WO2006002378A2 (en) 2004-06-23 2006-01-05 Avalon Pharmaceuticals Determining cancer-linked genes and therapeutic targets using molecular cytogenetic methods
CN102580084B (en) 2005-01-21 2016-11-23 健泰科生物技术公司 The fixed dosage of HER antibody is administered
JP5006802B2 (en) 2005-02-18 2012-08-22 チルドレンズ メディカル センター コーポレイション Cyr61 as a biomarker for cancer diagnosis and prognosis derived from epithelium
AU2006223374B2 (en) 2005-03-11 2011-07-21 Aspira Women’s Health Inc. Biomarkers for ovarian cancer and endometrial cancer: hepcidin
JP2006316040A (en) 2005-05-13 2006-11-24 Genentech Inc Herceptin(r) adjuvant treatment
US8014957B2 (en) 2005-12-15 2011-09-06 Fred Hutchinson Cancer Research Center Genes associated with progression and response in chronic myeloid leukemia and uses thereof
WO2007095186A2 (en) 2006-02-14 2007-08-23 Dana-Farber Cancer Institute, Inc. Compositions, kits, and methods for identification, assessment, prevention, and therapy of cancer
US20100015724A1 (en) 2006-08-17 2010-01-21 Peter Hornbeck Lysine acetylation sites
US20080107668A1 (en) 2006-08-30 2008-05-08 Immunotope, Inc. Cytotoxic t-lymphocyte-inducing immunogens for prevention, treatment, and diagnosis of cancer
US7615349B2 (en) 2006-09-07 2009-11-10 H. Lee Moffitt Cancer Center And Research Institute, Inc. Melanoma gene signature
WO2008059252A2 (en) 2006-11-15 2008-05-22 Oxford Biomedica (Uk) Limited Methods and composition fro t cell receptors which recognize 5t4 antigen
JP5663834B2 (en) 2008-03-14 2015-02-04 東ソー株式会社 Method for producing recombinant antibody
CA3146422A1 (en) 2008-03-18 2009-09-24 Genentech, Inc. Combinations of an anti-her2 antibody-drug conjugate and chemotherapeutic agents, and methods of use
HUE027332T2 (en) 2008-08-05 2016-09-28 Toray Industries Cancer detection method
PT2322221E (en) 2008-08-05 2014-09-19 Toray Industries Pharmaceutical composition for treatment and prevention of cancer
KR20160127146A (en) 2008-08-05 2016-11-02 도레이 카부시키가이샤 Immunity inducer
CA2771441C (en) 2009-08-19 2016-10-11 Merck Patent Gmbh Antibodies for the detection of integrin complexes in ffpe material
CA2773240C (en) 2009-09-22 2015-11-10 Volker Sandig Process for producing molecules containing specialized glycan structures
RU2418587C1 (en) * 2010-01-21 2011-05-20 Государственное образовательное учреждение высшего профессионального образования "Нижегородская государственная медицинская академия Федерального Агентства по здравоохранению и социальному развитию" (ГОУ ВПО "НижГМА Росздрава") Method of treating malignant brain tumours
PT2532743E (en) 2010-02-04 2015-08-04 Toray Industries Pharmaceutical composition for treatment and/or prevention of cancer
EP2532365B1 (en) 2010-02-04 2016-05-04 Toray Industries, Inc. Pharmaceutical composition for treatment and/or prevention of cancer
DK2532366T3 (en) 2010-02-04 2017-01-02 Toray Industries PHARMACEUTICAL COMPOSITION FOR TREATMENT AND / OR CANCER PREVENTION
ES2583777T3 (en) 2010-02-04 2016-09-22 Toray Industries, Inc. Pharmaceutical composition comprising anti CAPRIN-1 antibodies for the treatment and / or prevention of cancer
MX2012008991A (en) 2010-02-04 2012-09-07 Toray Industries Pharmaceutical agent for treatment and/or prevention of cancer.
JP5845899B2 (en) 2010-02-04 2016-01-20 東レ株式会社 Pharmaceutical composition for treatment and / or prevention of cancer
KR101271964B1 (en) 2010-07-08 2013-06-07 강원대학교산학협력단 A pharmaceutical composition for treating gallbladder carcinoma, a method for inhibiting growth or invasion of gallbladder carcinoma and a method for treating gallbladder carcinoma
WO2012013609A1 (en) 2010-07-26 2012-02-02 Bioréalités S.A.S. Methods and compositions for liver cancer therapy
JP5565183B2 (en) 2010-08-06 2014-08-06 宇部興産株式会社 Film production method
PT3351630T (en) * 2011-08-04 2019-12-30 Toray Industries Pharmaceutical composition comprising anti caprin-1 antibodies for treating and/or preventing cancer
JP6003650B2 (en) 2011-08-04 2016-10-05 東レ株式会社 Pharmaceutical composition for treatment and / or prevention of pancreatic cancer
US9796775B2 (en) 2011-08-04 2017-10-24 Toray Industries, Inc. Method for detecting pancreatic cancer
JP6107655B2 (en) 2012-03-30 2017-04-05 東レ株式会社 Pharmaceutical composition for treatment and / or prevention of gallbladder cancer
PL2832365T3 (en) 2012-03-30 2018-04-30 Toray Industries, Inc. Pharmaceutical composition for treatment and/or prevention of liver cancer

Also Published As

Publication number Publication date
WO2013125640A1 (en) 2013-08-29
AU2013223147B2 (en) 2017-10-05
BR112014021103A8 (en) 2018-01-23
EP2824114B1 (en) 2019-05-22
ES2739380T3 (en) 2020-01-30
DK2824114T3 (en) 2019-07-29
US9266958B2 (en) 2016-02-23
CN104114583A (en) 2014-10-22
KR102009236B1 (en) 2019-08-09
JP6187258B2 (en) 2017-08-30
CA2865020C (en) 2021-01-26
PT2824114T (en) 2019-08-05
RU2633505C2 (en) 2017-10-12
MX360211B (en) 2018-10-24
PL2824114T3 (en) 2019-11-29
KR20140130671A (en) 2014-11-11
JPWO2013125640A1 (en) 2015-07-30
RU2014138038A (en) 2016-04-10
HUE045461T2 (en) 2019-12-30
CN104114583B (en) 2019-11-19
EP2824114A1 (en) 2015-01-14
BR112014021103A2 (en) 2019-10-15
CA2865020A1 (en) 2013-08-29
EP2824114A4 (en) 2015-10-07
MX2014009749A (en) 2014-11-14
US20150017172A1 (en) 2015-01-15
AU2013223147A1 (en) 2014-09-11

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