IN2012DN00551A - - Google Patents
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- Publication number
- IN2012DN00551A IN2012DN00551A IN551DEN2012A IN2012DN00551A IN 2012DN00551 A IN2012DN00551 A IN 2012DN00551A IN 551DEN2012 A IN551DEN2012 A IN 551DEN2012A IN 2012DN00551 A IN2012DN00551 A IN 2012DN00551A
- Authority
- IN
- India
- Prior art keywords
- radioimmunoconjugate
- relates
- methods
- radioimmvmoconjugate
- hum195
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
- A61K51/1027—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against receptors, cell-surface antigens or cell-surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Optics & Photonics (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US22771009P | 2009-07-22 | 2009-07-22 | |
PCT/US2010/042885 WO2011011592A1 (en) | 2009-07-22 | 2010-07-22 | Methods for generating radioimmunoconjugates |
Publications (1)
Publication Number | Publication Date |
---|---|
IN2012DN00551A true IN2012DN00551A (ru) | 2015-06-12 |
Family
ID=43499411
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN551DEN2012 IN2012DN00551A (ru) | 2009-07-22 | 2010-07-22 |
Country Status (9)
Country | Link |
---|---|
US (1) | US9603954B2 (ru) |
EP (1) | EP2456472B1 (ru) |
JP (2) | JP5985392B2 (ru) |
CN (2) | CN102596258B (ru) |
CA (1) | CA2768658C (ru) |
HK (1) | HK1211304A1 (ru) |
IN (1) | IN2012DN00551A (ru) |
RU (2) | RU2565402C2 (ru) |
WO (1) | WO2011011592A1 (ru) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB201208309D0 (en) * | 2012-05-11 | 2012-06-27 | Algeta As | Complexes |
US20150157742A1 (en) * | 2013-12-11 | 2015-06-11 | The European Atomic Energy Community (Euratom), Represented By The European Commission | SYNTHESIS OF BIOLOGICAL COMPOUNDS LABELED WITH THE ALPHA EMITTER Ac-225 |
AU2015258801B2 (en) * | 2014-05-16 | 2020-10-08 | Memorial Sloan Kettering Cancer Center | One-step labeling of antibodies to high specific activity with actinium-225 |
AU2017376822B2 (en) | 2016-12-16 | 2023-08-03 | The Australian National University | Radiolabelled material for targeted administration |
EP3568205B1 (en) | 2017-01-12 | 2023-08-16 | Radiomedix Inc. | Treatment of cancer cells overexpressing somatostatin receptors using ocreotide derivatives chelated to radioisotopes |
US20200121815A1 (en) * | 2017-07-31 | 2020-04-23 | Actinium Pharmaceuticals, Inc. | Treatments for a hematological malignancy |
CN109550061A (zh) * | 2017-09-26 | 2019-04-02 | 南京江原安迪科正电子研究发展有限公司 | 一种用于放射性核素标记抗体的试剂盒及应用 |
EP4210752A1 (en) * | 2020-09-11 | 2023-07-19 | Actinium Pharmaceuticals, Inc. | Trophoblast glycoprotein radioimmunotherapy for the treatment of solid cancers |
WO2023183927A2 (en) | 2022-03-24 | 2023-09-28 | Actinium Pharmaceuticals, Inc. | Humanized anti-cd45 antibodies |
WO2023190402A1 (ja) * | 2022-03-30 | 2023-10-05 | 日本メジフィジックス株式会社 | 複合体の製造方法 |
WO2023240135A2 (en) | 2022-06-07 | 2023-12-14 | Actinium Pharmaceuticals, Inc. | Bifunctional chelators and conjugates |
Family Cites Families (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4001387A (en) | 1973-07-30 | 1977-01-04 | Medi-Physics, Inc. | Process for preparing radiopharmaceuticals |
US4305922A (en) | 1978-10-04 | 1981-12-15 | University Patents, Inc. | Labeling proteins with 99m-Tc by ligand exchange |
US4296785A (en) | 1979-07-09 | 1981-10-27 | Mallinckrodt, Inc. | System for generating and containerizing radioisotopes |
US4454106A (en) | 1982-06-07 | 1984-06-12 | Gansow Otto A | Use of metal chelate conjugated monoclonal antibodies |
US4472509A (en) | 1982-06-07 | 1984-09-18 | Gansow Otto A | Metal chelate conjugated monoclonal antibodies |
GB8308235D0 (en) | 1983-03-25 | 1983-05-05 | Celltech Ltd | Polypeptides |
US4732864A (en) | 1983-10-06 | 1988-03-22 | E. I. Du Pont De Nemours And Company | Trace-labeled conjugates of metallothionein and target-seeking biologically active molecules |
US4894364A (en) | 1983-10-26 | 1990-01-16 | Greer Sheldon B | Method and materials for sensitizing neoplastic tissue to radiation |
US4828991A (en) | 1984-01-31 | 1989-05-09 | Akzo N.V. | Tumor specific monoclonal antibodies |
US4663129A (en) | 1985-01-30 | 1987-05-05 | The United States Of America As Represented By The United States Department Of Energy | Isotopic generator for bismuth-212 and lead-212 from radium |
GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
US5306509A (en) | 1987-03-17 | 1994-04-26 | Turner Robert E | Prevention and treatment of oral lesions |
AU2068588A (en) | 1987-08-12 | 1989-02-16 | Immunomedics Inc. | Preparation of radiolabeled conjugates |
US4833329A (en) | 1987-11-20 | 1989-05-23 | Mallinckrodt, Inc. | System for generating and containerizing radioisotopes |
US5612016A (en) * | 1988-04-01 | 1997-03-18 | Immunomedics, Inc. | Conjugates of antibodies and bifunctional ligands |
JPH0720989B2 (ja) | 1988-05-25 | 1995-03-08 | アメリカ合衆国 | 大環状キレート化合物の抱合体と診断的テスト方法 |
US4923985A (en) | 1988-05-25 | 1990-05-08 | The United States Of America As Represented By The Department Of Health & Human Services | Process for synthesizing macrocyclic chelates |
US5292868A (en) | 1989-05-26 | 1994-03-08 | Akzo N.V. | Chelating agents for attaching metal ions to proteins |
WO1990015625A1 (en) | 1989-06-19 | 1990-12-27 | Akzo N.V. | RADIOIMMUNOTHERAPY USING α-PARTICLES EMISSION |
CA2063551C (en) | 1989-07-12 | 2000-05-16 | Jacobus D.M. Herscheid | Method for preparing radiodiagnostic gaseous radionuclide and apparatus |
US5443816A (en) | 1990-08-08 | 1995-08-22 | Rhomed Incorporated | Peptide-metal ion pharmaceutical preparation and method |
LU87684A1 (de) | 1990-02-23 | 1991-10-08 | Euratom | Verfahren zur erzeugung von aktinium-225 und wismut-213 |
US5038046A (en) | 1990-07-10 | 1991-08-06 | Biotechnetics | Method and generator for producing radioactive lead-212 |
US6403771B1 (en) | 1991-02-19 | 2002-06-11 | Actinium Pharmaceuticals, Limited | Method and means for site directed therapy |
CA2100709C (en) | 1992-07-27 | 2004-03-16 | Maurits W. Geerlings | Method and means for site directed therapy |
IL113610A0 (en) * | 1994-06-03 | 1995-08-31 | Immunomedics Inc | A method of radiolabeling a protein, radiolabeled proteins prepared thereby and diagnostic kits containing the same |
AU742626B2 (en) | 1998-05-20 | 2002-01-10 | Immunomedics Inc. | Therapeutics using a bispecific anti-HLA class II invariant chain X anti-pathogen antibody |
DE69937797D1 (de) | 1998-05-26 | 2008-01-31 | Sloan Kettering Inst Cancer | Alpha-emittierende konstrukte sowie deren verwendung |
EP1089766B1 (en) | 1998-06-22 | 2010-03-17 | Immunomedics, Inc. | Use of bi-specific antibodies for pre-targeting diagnosis and therapy |
CA2422291C (en) | 2000-09-15 | 2011-03-08 | Sloan-Kettering Institute For Cancer Research | Targeted alpha particle therapy using actinium-225 conjugates |
US6670456B2 (en) | 2001-02-28 | 2003-12-30 | Dow Global Technologies Inc. | Actinium-225 complexes and conjugates for targeted radiotherapy |
JP2004527528A (ja) | 2001-04-09 | 2004-09-09 | プロジェニクス・ファーマスーティカルズ・インコーポレイテッド | 抗cd19免疫毒素 |
US7666414B2 (en) | 2001-06-01 | 2010-02-23 | Cornell Research Foundation, Inc. | Methods for treating prostate cancer using modified antibodies to prostate-specific membrane antigen |
EP2239274A1 (en) | 2002-01-03 | 2010-10-13 | Bayer Schering Pharma AG | New methods for diagnosis and treatment of tumours |
US20040022726A1 (en) * | 2002-06-03 | 2004-02-05 | Goldenberg David M. | Methods and compositions for intravesical therapy of bladder cancer |
US20030086868A1 (en) * | 2002-08-12 | 2003-05-08 | Dangshe Ma | Actinium-225 complexes and conjugates for radioimmunotherapy |
US20060058218A1 (en) * | 2004-09-10 | 2006-03-16 | General Electric Company | Solid phase conjugation of complexing agents and targeting moieties |
US7736647B2 (en) | 2005-06-15 | 2010-06-15 | Monoclonal Antibodies Therapeutics | Anti-CD71 monoclonal antibodies and uses thereof for treating malignant tumor cells |
EP2015775B1 (en) | 2006-05-03 | 2011-06-01 | Bayer Schering Pharma Aktiengesellschaft | Combination of an anti edb fibronectin domain antibody l19-sip and an anti-egfr antibody |
-
2010
- 2010-07-22 US US13/386,316 patent/US9603954B2/en active Active
- 2010-07-22 EP EP10802893.7A patent/EP2456472B1/en active Active
- 2010-07-22 RU RU2012106301/15A patent/RU2565402C2/ru active
- 2010-07-22 CN CN201080036704.4A patent/CN102596258B/zh active Active
- 2010-07-22 CN CN201510083376.8A patent/CN104710504B/zh active Active
- 2010-07-22 JP JP2012521780A patent/JP5985392B2/ja active Active
- 2010-07-22 CA CA2768658A patent/CA2768658C/en active Active
- 2010-07-22 WO PCT/US2010/042885 patent/WO2011011592A1/en active Application Filing
- 2010-07-22 IN IN551DEN2012 patent/IN2012DN00551A/en unknown
- 2010-07-22 RU RU2015137512A patent/RU2704802C2/ru active
-
2015
- 2015-12-09 HK HK15112145.2A patent/HK1211304A1/xx unknown
-
2016
- 2016-08-03 JP JP2016152696A patent/JP2016199583A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
CN102596258B (zh) | 2015-01-28 |
RU2012106301A (ru) | 2013-08-27 |
CA2768658A1 (en) | 2011-01-27 |
CN104710504B (zh) | 2019-09-13 |
WO2011011592A1 (en) | 2011-01-27 |
RU2565402C2 (ru) | 2015-10-20 |
JP2013500258A (ja) | 2013-01-07 |
CN102596258A (zh) | 2012-07-18 |
HK1211304A1 (en) | 2016-05-20 |
RU2704802C2 (ru) | 2019-10-31 |
JP2016199583A (ja) | 2016-12-01 |
CN104710504A (zh) | 2015-06-17 |
EP2456472B1 (en) | 2024-03-27 |
US20120220754A1 (en) | 2012-08-30 |
EP2456472A4 (en) | 2014-08-27 |
EP2456472A1 (en) | 2012-05-30 |
CA2768658C (en) | 2018-04-03 |
US9603954B2 (en) | 2017-03-28 |
RU2015137512A (ru) | 2018-12-25 |
EP2456472C0 (en) | 2024-03-27 |
RU2015137512A3 (ru) | 2019-04-02 |
JP5985392B2 (ja) | 2016-09-06 |
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