IL98909A0 - 3-tetrahydrofuran substituted cephalosporin,carbadethiacephalosporin and oxadethiacephalosporin derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

3-tetrahydrofuran substituted cephalosporin,carbadethiacephalosporin and oxadethiacephalosporin derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number: IL98909A0
Authority: IL; Israel
Prior art keywords: carbadethiacephalosporin; preparation; pharmaceutical compositions; compositions containing; substituted cephalosporin
Prior art date: 1990-07-24

Application number

IL98909A

Other languages

English (en)

Original Assignee

Beecham Group Plc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-07-24

Filing date

1991-07-22

Publication date

1992-07-15

1990-07-24 Priority claimed from GB909016189A external-priority patent/GB9016189D0/en

1991-05-02 Priority claimed from GB919109540A external-priority patent/GB9109540D0/en

1991-07-22 Application filed by Beecham Group Plc filed Critical Beecham Group Plc

1992-07-15 Publication of IL98909A0 publication Critical patent/IL98909A0/xx

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
- C07D463/16—Nitrogen atoms
- C07D463/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
- C07D463/20—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D463/22—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by nitrogen atoms
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Communicable Diseases (AREA)
Pharmacology & Pharmacy (AREA)
Oncology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Cephalosporin Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

IL98909A 1990-07-24 1991-07-22 3-tetrahydrofuran substituted cephalosporin,carbadethiacephalosporin and oxadethiacephalosporin derivatives,their preparation and pharmaceutical compositions containing them IL98909A0 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB909016189A GB9016189D0 (en)	1990-07-24	1990-07-24	Novel compounds
GB919109540A GB9109540D0 (en)	1991-05-02	1991-05-02	Novel compounds

Publications (1)

Publication Number	Publication Date
IL98909A0 true IL98909A0 (en)	1992-07-15

Family

ID=26297372

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL98909A IL98909A0 (en)	1990-07-24	1991-07-22	3-tetrahydrofuran substituted cephalosporin,carbadethiacephalosporin and oxadethiacephalosporin derivatives,their preparation and pharmaceutical compositions containing them

Country Status (26)

Country	Link
EP (2)	EP0540606A1 (zh)
JP (2)	JPH05509089A (zh)
KR (1)	KR100189075B1 (zh)
CN (2)	CN1061046C (zh)
AP (1)	AP832A (zh)
AT (1)	ATE185567T1 (zh)
AU (1)	AU648329B2 (zh)
CA (2)	CA2359744C (zh)
CZ (1)	CZ6493A3 (zh)
DE (2)	DE69131714T2 (zh)
DK (1)	DK0540609T3 (zh)
ES (1)	ES2137162T3 (zh)
FI (1)	FI930270A (zh)
GR (1)	GR3031711T3 (zh)
HU (1)	HUT63628A (zh)
IE (1)	IE912569A1 (zh)
IL (1)	IL98909A0 (zh)
LU (1)	LU91290I2 (zh)
MX (1)	MX9100317A (zh)
MY (1)	MY106399A (zh)
NL (1)	NL300249I2 (zh)
NO (1)	NO930226L (zh)
NZ (1)	NZ239061A (zh)
PT (1)	PT98426A (zh)
WO (2)	WO1992001696A1 (zh)
YU (1)	YU129691A (zh)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9125645D0 (en) *	1991-12-03	1992-01-29	Smithkline Beecham Plc	Novel compounds
JPH07503460A (ja) *	1992-01-22	1995-04-13	ファイザー・インコーポレイテッド	２−イソセフェムおよびオキサセファム誘導体，それらの製法，その中間体および抗菌剤としての使用
GB9212609D0 (en) *	1992-06-13	1992-07-29	Smithkline Beecham Plc	Novel compounds
GB9213567D0 (en) *	1992-06-26	1992-08-12	Smithkline Beecham Plc	Novel compounds
GB9424847D0 (en) *	1994-12-09	1995-02-08	Smithkline Beecham Plc	Novel process
GB2300856A (en) *	1995-05-16	1996-11-20	Pfizer Ltd	Beta-lactam preparation
AU4398297A (en) *	1996-10-02	1998-04-24	Daiichi Pharmaceutical Co., Ltd.	Method for esterifying carboxylic compounds
FR2776292B1 (fr) *	1998-03-20	2004-09-10	Oncopharm	Cephalotaxanes porteurs de chaine laterale et leur procede de synthese
GB0019124D0 (en)	2000-08-03	2000-09-27	Pfizer	Novel process
KR100526379B1 (ko) *	2000-12-04	2005-11-08	화이자 프로덕츠 인크.	세팔로스포린 제조에 유용한 커플링법 및 중간체
RU2237671C1 (ru) *	2000-12-04	2004-10-10	Пфайзер Продактс Инк.	Способ и сложноэфирные производные, используемые для получения цефалоспоринов
US7378408B2 (en) *	2001-11-30	2008-05-27	Pfizer Inc.	Methods of treatment and formulations of cephalosporin
KR100710555B1 (ko)	2001-12-04	2007-04-24	에스케이 주식회사	광학적으로 순수한 (ｒ)-폼 또는 (ｓ)-폼의테트라히드로퓨라닐 케톤의 제조방법
LT2794627T (lt)	2011-12-22	2019-01-10	Alios Biopharma, Inc.	Pakeistieji nukleozidai, nukleotidai ir jų analogai
US9441007B2 (en)	2012-03-21	2016-09-13	Alios Biopharma, Inc.	Substituted nucleosides, nucleotides and analogs thereof
USRE48171E1 (en)	2012-03-21	2020-08-25	Janssen Biopharma, Inc.	Substituted nucleosides, nucleotides and analogs thereof
HUE029038T2 (en)	2012-05-25	2017-01-30	Janssen Sciences Ireland Uc	Uracil spirooxetan nucleosides
KR102168621B1 (ko)	2012-12-21	2020-10-22	얀센 바이오파마, 인코퍼레이트.	치환된 뉴클레오사이드, 뉴클레오타이드 및 그것의 유사체
CN105254648B (zh) *	2015-11-13	2018-04-03	广东温氏大华农生物科技有限公司	一种头孢维星及其钠盐的合成方法
GB2575261B (en)	2018-07-02	2022-03-09	Norbrook Lab Ltd	Intermediates in the synthesis of C3-substituted cephalosporins
AU2019324170A1 (en)	2018-08-23	2021-02-18	Seagen, Inc.	Anti-TIGIT antibodies
CR20220316A (es)	2019-12-06	2022-10-07	Vertex Pharma	Tetrahidrofuranos sustituidos como moduladores de canales de sodio
EP4106876A1 (en)	2020-02-18	2022-12-28	Gilead Sciences, Inc.	Antiviral compounds
TWI794742B (zh)	2020-02-18	2023-03-01	美商基利科學股份有限公司	抗病毒化合物
CN114213433B (zh) *	2020-06-08	2023-03-24	重庆医药高等专科学校	C-3位四氢呋喃取代的头孢菌素-铁载体耦合物的制备方法
KR20230170745A (ko)	2021-04-16	2023-12-19	길리애드 사이언시즈, 인코포레이티드	아미드를 사용한 카르바뉴클레오시드를 제조하는 방법
WO2022256622A1 (en)	2021-06-04	2022-12-08	Vertex Pharmaceuticals Incorporated	N-(hydroxyalkyl (hetero)aryl) tetrahydrofuran carboxamides as modulators of sodium channels

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BE793448A (fr) *	1971-12-31	1973-06-28	Roussel Uclaf	Procede de preparation de nouveaux derives des cephalosporines et produits obtenus
FR2197573A1 (en) *	1972-09-07	1974-03-29	Roussel Uclaf	7-substd-phenylacetamido-cephalosporin derivs - - antibiotics active against streptococci and staphylococci
BE791160A (fr) *	1972-01-03	1973-05-09	Beecham Group Ltd	Nouveaux cephemes substitues
BE791161A (fr) *	1972-01-03	1973-05-09	Beecham Group Ltd	Procede pour la preparation d'analogues des cephalosporines
NL7305936A (zh) *	1972-05-05	1973-11-07
JPS5849382A (ja) *	1981-09-18	1983-03-23	Kyowa Hakko Kogyo Co Ltd	β−ラクタム化合物
GB8821797D0 (en) *	1988-09-16	1988-10-19	Beecham Group Plc	Novel compounds
ES2121745T3 (es) *	1989-03-30	1998-12-16	Pfizer	Cefalosporinas y sus homologos, procedimiento para su preparacion y composiciones farmaceuticas.

1991
- 1991-07-16 MY MYPI91001321A patent/MY106399A/en unknown
- 1991-07-22 EP EP91913545A patent/EP0540606A1/en not_active Withdrawn
- 1991-07-22 JP JP3512255A patent/JPH05509089A/ja active Pending
- 1991-07-22 ES ES91913583T patent/ES2137162T3/es not_active Expired - Lifetime
- 1991-07-22 EP EP91913583A patent/EP0540609B1/en not_active Expired - Lifetime
- 1991-07-22 IL IL98909A patent/IL98909A0/xx unknown
- 1991-07-22 JP JP3512368A patent/JP2851428B2/ja not_active Expired - Lifetime
- 1991-07-22 DE DE69131714T patent/DE69131714T2/de not_active Expired - Lifetime
- 1991-07-22 AU AU82224/91A patent/AU648329B2/en not_active Expired
- 1991-07-22 IE IE256991A patent/IE912569A1/en not_active IP Right Cessation
- 1991-07-22 AT AT91913583T patent/ATE185567T1/de active
- 1991-07-22 CZ CS9364A patent/CZ6493A3/cs unknown
- 1991-07-22 DK DK91913583T patent/DK0540609T3/da active
- 1991-07-22 NZ NZ239061A patent/NZ239061A/en not_active IP Right Cessation
- 1991-07-22 KR KR1019930700216A patent/KR100189075B1/ko not_active IP Right Cessation
- 1991-07-22 MX MX9100317A patent/MX9100317A/es unknown
- 1991-07-22 WO PCT/GB1991/001228 patent/WO1992001696A1/en active IP Right Grant
- 1991-07-22 HU HU93177A patent/HUT63628A/hu unknown
- 1991-07-22 CA CA002359744A patent/CA2359744C/en not_active Expired - Lifetime
- 1991-07-22 AP APAP/P/1991/000305A patent/AP832A/en active
- 1991-07-22 WO PCT/GB1991/001227 patent/WO1992001695A1/en not_active Application Discontinuation
- 1991-07-22 CA CA002087967A patent/CA2087967C/en not_active Expired - Lifetime
- 1991-07-22 DE DE200612000065 patent/DE122006000065I2/de active Active
- 1991-07-23 YU YU129691A patent/YU129691A/sh unknown
- 1991-07-23 PT PT98426A patent/PT98426A/pt not_active Application Discontinuation
- 1991-07-24 CN CN91105783A patent/CN1061046C/zh not_active Expired - Lifetime
1993
- 1993-01-22 FI FI930270A patent/FI930270A/fi unknown
- 1993-01-22 NO NO93930226A patent/NO930226L/no unknown
1998
- 1998-11-14 CN CN98122407A patent/CN1111410C/zh not_active Expired - Lifetime
1999
- 1999-11-03 GR GR990402803T patent/GR3031711T3/el unknown
2006
- 2006-11-22 LU LU91290C patent/LU91290I2/fr unknown
- 2006-11-27 NL NL300249C patent/NL300249I2/en unknown

Also Published As

Publication number	Publication date
GR3031711T3 (en)	2000-02-29
FI930270A0 (fi)	1993-01-22
NL300249I1 (nl)	2007-02-01
EP0540609A1 (en)	1993-05-12
DE69131714D1 (de)	1999-11-18
MY106399A (en)	1995-05-30
HU9300177D0 (en)	1993-04-28
KR100189075B1 (ko)	1999-06-01
KR930701456A (ko)	1993-06-11
ATE185567T1 (de)	1999-10-15
AU8222491A (en)	1992-02-18
CN1060469A (zh)	1992-04-22
HUT63628A (en)	1993-09-28
PT98426A (pt)	1992-05-29
YU129691A (sh)	1994-01-20
MX9100317A (es)	1992-02-28
DE122006000065I1 (de)	2007-03-01
NO930226L (no)	1993-03-23
JP2851428B2 (ja)	1999-01-27
AP832A (en)	2000-05-03
ES2137162T3 (es)	1999-12-16
CA2359744C (en)	2007-02-13
AU648329B2 (en)	1994-04-21
CN1111410C (zh)	2003-06-18
CN1061046C (zh)	2001-01-24
EP0540609B1 (en)	1999-10-13
DK0540609T3 (da)	1999-12-27
IE912569A1 (en)	1992-01-29
CA2087967A1 (en)	1992-01-25
NO930226D0 (no)	1993-01-22
CZ6493A3 (en)	1994-04-13
CA2359744A1 (en)	1992-02-06
JPH05509089A (ja)	1993-12-16
JPH05509305A (ja)	1993-12-22
DE69131714T2 (de)	2000-02-24
FI930270A (fi)	1993-03-22
NZ239061A (en)	1993-11-25
NL300249I2 (en)	2007-02-01
WO1992001695A1 (en)	1992-02-06
WO1992001696A1 (en)	1992-02-06
EP0540606A1 (en)	1993-05-12
CA2087967C (en)	2002-09-10
DE122006000065I2 (de)	2007-09-13
AP9100305A0 (en)	1991-07-31
CN1223859A (zh)	1999-07-28
LU91290I2 (fr)	2007-01-22

Publication	Publication Date	Title
IL98909A0 (en)	1992-07-15	3-tetrahydrofuran substituted cephalosporin,carbadethiacephalosporin and oxadethiacephalosporin derivatives,their preparation and pharmaceutical compositions containing them
IL99225A0 (en)	1992-07-15	3-amidopyrazole derivatives,their preparation and pharmaceutical compositions containing them
IL100262A0 (en)	1992-09-06	Alpha-oxoacetamide derivatives,their preparation and pharmaceutical compositions containing them
IL101864A0 (en)	1992-12-30	Thiopyranopyrrole derivatives,their preparation and pharmaceutical compositions containing them
NZ238545A (en)	1993-08-26	Dialkoxy-pyridinyl-benzimidazole derivatives; preparation and pharmaceutical compositions thereof
IL96516A0 (en)	1991-08-16	Benzofuran derivatives,their preparation and pharmaceutical compositions containing them
IL97050A0 (en)	1992-03-29	4-isoxazolecarboxamide derivatives,pharmaceutical compositions containing them and their preparation
IL85972A0 (en)	1988-09-30	Cephalosporin derivatives,their manufacture and pharmaceutical compositions containing them
IL101882A0 (en)	1992-12-30	Benzofuran derivatives,their preparation and pharmaceutical compositions containing them
IL98542A0 (en)	1992-07-15	Benzoquinazoline derivatives,their preparation and pharmaceutical compositions containing them
IL98756A0 (en)	1992-07-15	Pharmaceutical compositions containing benzeneacetamid derivatives,certain such novel compounds and their preparation
IL101351A0 (en)	1992-11-15	Benzofuran derivatives,their preparation and pharmaceutical compositions containing them
IL103020A0 (en)	1993-02-21	Imidazopyridine derivatives,their preparation and pharmaceutical compositions containing them
IL103818A0 (en)	1993-04-04	Cephalosporin derivatives,their manufacture and pharmaceutical compositions containing them
IL101888A0 (en)	1992-12-30	Benzofuran derivatives,their preparation and pharmaceutical compositions containing them
IL87374A0 (en)	1989-01-31	Cephalosporin derivatives,their manufacture and pharmaceutical compositions containing them
IL94946A0 (en)	1991-06-10	3-substituted vinyl cephalosporin derivatives,their preparation and pharmaceutical compositions containing them
IL98863A0 (en)	1992-07-15	Carbostyril derivatives,their preparation and pharmaceutical compositions containing them
IL92857A0 (en)	1990-09-17	Cephalosporin compounds,their preparation and pharmaceutical compositions containing them
IL102500A0 (en)	1993-01-14	3-deoxy-mannosamine derivatives,their preparation and pharmaceutical compositions containing them
IL107302A0 (en)	1994-01-25	Benzofuran derivatives, their preparation and pharmaceutical compositions comprising them
IL85970A0 (en)	1988-09-30	Cephalosporin derivatives,their manufacture and pharmaceutical compositions containing them
IL99561A0 (en)	1992-08-18	Heterocyclic compounds,their preparation and pharmaceutical compositions containing them
IL106549A0 (en)	1993-12-08	Heterocyclic derivatives,their preparation and pharmaceutical compositions containing them
IL90324A0 (en)	1989-12-15	2-aminoethanol derivatives,their preparation and pharmaceutical compositions containing them