IL96917A0 - 4,4'-(9h-fluoren-9-ylidenebis(methylene)-bispyrimidine and pharmaceutical compositions containing it - Google Patents

4,4'-(9h-fluoren-9-ylidenebis(methylene)-bispyrimidine and pharmaceutical compositions containing it

Info

Publication number
IL96917A0
IL96917A0 IL96917A IL9691791A IL96917A0 IL 96917 A0 IL96917 A0 IL 96917A0 IL 96917 A IL96917 A IL 96917A IL 9691791 A IL9691791 A IL 9691791A IL 96917 A0 IL96917 A0 IL 96917A0
Authority
IL
Israel
Prior art keywords
bispyrimidine
ylidenebis
fluoren
methylene
pharmaceutical compositions
Prior art date
Application number
IL96917A
Other languages
English (en)
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont filed Critical Du Pont
Publication of IL96917A0 publication Critical patent/IL96917A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/26—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Psychiatry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
IL96917A 1990-01-12 1991-01-10 4,4'-(9h-fluoren-9-ylidenebis(methylene)-bispyrimidine and pharmaceutical compositions containing it IL96917A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/464,433 US5087628A (en) 1990-01-12 1990-01-12 4,4'-[9H-fluoren-9-ylidenebis (methylene)]bispyrimidine for treating neurological disorders

Publications (1)

Publication Number Publication Date
IL96917A0 true IL96917A0 (en) 1992-03-29

Family

ID=23843938

Family Applications (1)

Application Number Title Priority Date Filing Date
IL96917A IL96917A0 (en) 1990-01-12 1991-01-10 4,4'-(9h-fluoren-9-ylidenebis(methylene)-bispyrimidine and pharmaceutical compositions containing it

Country Status (10)

Country Link
US (1) US5087628A (xx)
EP (1) EP0509033A4 (xx)
JP (1) JP2942626B2 (xx)
AU (1) AU646240B2 (xx)
CA (1) CA2073694A1 (xx)
IE (1) IE910084A1 (xx)
IL (1) IL96917A0 (xx)
NZ (1) NZ236737A (xx)
WO (1) WO1991010433A1 (xx)
ZA (1) ZA91236B (xx)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2051151C1 (ru) * 1992-01-16 1995-12-27 Дзе Дюпон Мерк Фармасьютикал Компани Азотсодержащие гетероциклические производные флуорена
WO1994025438A1 (en) * 1993-04-28 1994-11-10 The Du Pont Merck Pharmaceutical Company Novel trisubstituted aromatic amines useful for the treatment of cognitive deficits
US5760246A (en) 1996-12-17 1998-06-02 Biller; Scott A. Conformationally restricted aromatic inhibitors of microsomal triglyceride transfer protein and method

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5173489A (en) * 1986-04-10 1992-12-22 The Dupont Merck Pharmaceutical Co. α,α-disubstituted aromatics and heteroaromatics as cognition enhancers
US4760083A (en) * 1986-04-10 1988-07-26 E. I. Dupont De Nemours & Company 3,3-disubstituted indolines
US4806651A (en) * 1987-10-07 1989-02-21 E. I. Du Pont De Nemours And Company Process for preparing 3,3-disubstituted indolines

Also Published As

Publication number Publication date
WO1991010433A1 (en) 1991-07-25
AU7154591A (en) 1991-08-05
EP0509033A4 (en) 1993-02-24
IE910084A1 (en) 1991-07-17
CA2073694A1 (en) 1991-07-13
US5087628A (en) 1992-02-11
EP0509033A1 (en) 1992-10-21
NZ236737A (en) 1992-01-29
JP2942626B2 (ja) 1999-08-30
JPH05504765A (ja) 1993-07-22
ZA91236B (en) 1992-09-30
AU646240B2 (en) 1994-02-17

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