IL95607A0 - 3-alkyl-4-phenyl-tetrahydro benzazapine-2-one derivatives - Google Patents

3-alkyl-4-phenyl-tetrahydro benzazapine-2-one derivatives

Info

Publication number
IL95607A0
IL95607A0 IL95607A IL9560790A IL95607A0 IL 95607 A0 IL95607 A0 IL 95607A0 IL 95607 A IL95607 A IL 95607A IL 9560790 A IL9560790 A IL 9560790A IL 95607 A0 IL95607 A0 IL 95607A0
Authority
IL
Israel
Prior art keywords
benzazapine
tetrahydro
phenyl
derivatives
alkyl
Prior art date
Application number
IL95607A
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of IL95607A0 publication Critical patent/IL95607A0/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/02Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D223/06Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D223/08Oxygen atoms
    • C07D223/10Oxygen atoms attached in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16Benzazepines; Hydrogenated benzazepines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL95607A 1985-12-12 1990-09-07 3-alkyl-4-phenyl-tetrahydro benzazapine-2-one derivatives IL95607A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80818385A 1985-12-12 1985-12-12
US91713086A 1986-10-09 1986-10-09

Publications (1)

Publication Number Publication Date
IL95607A0 true IL95607A0 (en) 1991-06-30

Family

ID=27123095

Family Applications (2)

Application Number Title Priority Date Filing Date
IL80668A IL80668A0 (en) 1985-12-12 1986-11-17 Benzazepine derivatives and pharmaceutical compositions containing the same
IL95607A IL95607A0 (en) 1985-12-12 1990-09-07 3-alkyl-4-phenyl-tetrahydro benzazapine-2-one derivatives

Family Applications Before (1)

Application Number Title Priority Date Filing Date
IL80668A IL80668A0 (en) 1985-12-12 1986-11-17 Benzazepine derivatives and pharmaceutical compositions containing the same

Country Status (18)

Country Link
EP (1) EP0229329B1 (en)
JP (1) JPH0686435B2 (en)
KR (1) KR900001177B1 (en)
CN (1) CN1017894B (en)
AU (1) AU591726B2 (en)
CA (2) CA1271748C (en)
CZ (1) CZ278686B6 (en)
DE (1) DE3688788T2 (en)
DK (1) DK163731C (en)
ES (1) ES2058059T3 (en)
FI (1) FI83775C (en)
HU (2) HU199806B (en)
IE (1) IE61757B1 (en)
IL (2) IL80668A0 (en)
NO (1) NO168820C (en)
NZ (1) NZ218292A (en)
PL (2) PL151569B1 (en)
PT (1) PT83917B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4752645A (en) * 1986-10-09 1988-06-21 E. R. Squibb & Sons, Inc. Benzazepine derivatives
US4771047A (en) * 1987-07-27 1988-09-13 E. R. Squibb & Sons, Inc. Benzazepine derivatives
US4774239A (en) * 1987-08-26 1988-09-27 E. R. Squibb & Sons, Inc. Benzazepine derivatives
DE3807922A1 (en) * 1988-03-10 1989-09-21 Boehringer Mannheim Gmbh SUBSTITUTED HETEROCYCLES, METHOD FOR THE PRODUCTION THEREOF, AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS
US4902684A (en) * 1988-06-20 1990-02-20 E. R. Squibb & Sons, Inc. Benzazepine and benzothiazepine derivatives
US4946840A (en) * 1989-04-06 1990-08-07 E. R. Squibb & Sons, Inc. Benzazepine and benzothiazepine derivatives
AU2001218083A1 (en) * 2000-01-26 2001-08-07 Warner Lambert Company Ace inhibitor-vasopressin antagonist combinations
US20030008860A1 (en) 2002-05-09 2003-01-09 Bakker-Arkema Rebecca Guggemos Treatment of congestive heart failure
JP2022055368A (en) * 2019-02-19 2022-04-08 株式会社三和化学研究所 Method for producing benzoazepine derivative and intermediate thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3075967A (en) 1961-06-12 1963-01-29 Olin Mathieson Benzothiazines
US3330823A (en) 1964-12-16 1967-07-11 Squibb & Sons Inc N-amino-loweralkylene-benzo-lactams
CA1271747A (en) * 1985-06-12 1990-07-17 David M. Floyd Benzazepines derivatives

Also Published As

Publication number Publication date
IL80668A0 (en) 1987-02-27
CA1294617C (en) 1992-01-21
PL150461B1 (en) 1990-05-31
FI865056A (en) 1987-06-13
AU591726B2 (en) 1989-12-14
JPS62164668A (en) 1987-07-21
NO168820C (en) 1992-04-08
NZ218292A (en) 1988-10-28
AU6530386A (en) 1987-06-18
IE863224L (en) 1988-04-09
KR900001177B1 (en) 1990-02-27
NO168820B (en) 1991-12-30
FI83775B (en) 1991-05-15
NO865012D0 (en) 1986-12-11
HU196760B (en) 1989-01-30
FI865056A0 (en) 1986-12-11
PT83917B (en) 1988-06-23
HU199806B (en) 1990-03-28
DK163731B (en) 1992-03-30
PL151569B1 (en) 1990-09-28
CA1271748A (en) 1990-07-17
PL262928A1 (en) 1988-08-04
CZ915486A3 (en) 1994-01-19
DK163731C (en) 1992-08-31
ES2058059T3 (en) 1994-11-01
CA1271748C (en) 1990-07-17
EP0229329B1 (en) 1993-07-28
JPH0686435B2 (en) 1994-11-02
FI83775C (en) 1991-08-26
CZ278686B6 (en) 1994-05-18
IE61757B1 (en) 1994-11-30
CN1017894B (en) 1992-08-19
KR870005999A (en) 1987-07-08
PL271723A1 (en) 1988-12-08
EP0229329A1 (en) 1987-07-22
PT83917A (en) 1987-01-01
DK595686D0 (en) 1986-12-11
DE3688788T2 (en) 1994-03-03
DE3688788D1 (en) 1993-09-02
CN86108530A (en) 1987-06-17
NO865012L (en) 1987-06-15
HUT43572A (en) 1987-11-30
DK595686A (en) 1987-06-13

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