IL76854A - Oxindole derivatives - Google Patents
Oxindole derivativesInfo
- Publication number
- IL76854A IL76854A IL76854A IL7685485A IL76854A IL 76854 A IL76854 A IL 76854A IL 76854 A IL76854 A IL 76854A IL 7685485 A IL7685485 A IL 7685485A IL 76854 A IL76854 A IL 76854A
- Authority
- IL
- Israel
- Prior art keywords
- oxindole derivatives
- oxindole
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/58—[b]- or [c]-condensed
- C07D209/70—[b]- or [c]-condensed containing carbocyclic rings other than six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL87997A IL87997A (en) | 1984-10-31 | 1985-10-28 | Oxindole anti-inflammatory agents and pharmaceutical compositions comprising them |
IL87997A IL87997A0 (en) | 1984-10-31 | 1988-10-10 | Oxindole anti-inflammatory agents and pharmaceutical compositions comprising them |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/666,953 US4644005A (en) | 1984-10-31 | 1984-10-31 | Oxindole antiinflammatory agents |
US06/762,998 US4686224A (en) | 1984-10-31 | 1985-08-06 | Oxindole antiinflammatory agents |
Publications (2)
Publication Number | Publication Date |
---|---|
IL76854A0 IL76854A0 (en) | 1986-02-28 |
IL76854A true IL76854A (en) | 1989-05-15 |
Family
ID=27099577
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL76854A IL76854A (en) | 1984-10-31 | 1985-10-28 | Oxindole derivatives |
Country Status (16)
Country | Link |
---|---|
US (1) | US4686224A (xx) |
EP (1) | EP0181136B1 (xx) |
KR (1) | KR870001269B1 (xx) |
AU (1) | AU555051B2 (xx) |
CA (1) | CA1247099A (xx) |
DE (1) | DE3585719D1 (xx) |
DK (1) | DK163990C (xx) |
ES (1) | ES8707731A1 (xx) |
FI (1) | FI81340C (xx) |
GR (1) | GR852629B (xx) |
HU (1) | HU194168B (xx) |
IE (1) | IE58207B1 (xx) |
IL (1) | IL76854A (xx) |
PH (3) | PH20985A (xx) |
PL (2) | PL150842B1 (xx) |
PT (1) | PT81393B (xx) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1990008145A1 (en) * | 1989-01-10 | 1990-07-26 | Pfizer Inc. | Anti-inflammatory 1-heteroaryl-3-acyl-2-oxindoles |
WO1990008146A1 (en) * | 1989-01-10 | 1990-07-26 | Pfizer Inc. | Anti-inflammatory 1-heteroaryl-oxindole-3-carboxamides |
JPH0717589B2 (ja) * | 1990-01-22 | 1995-03-01 | ファイザー製薬株式会社 | 新規1,3―ジカルボニル化合物およびその組成物 |
CH687764A5 (de) * | 1992-07-02 | 1997-02-14 | Lonza Ag Gampel Wallis Geschof | Verfahren zur Herstellung von 7-Acylindolen. |
US5449788A (en) * | 1994-01-28 | 1995-09-12 | Catalytica, Inc. | Process for preparing 2-oxindole-1-carboxamides |
GB9414139D0 (en) * | 1994-07-13 | 1994-08-31 | Smithkline Beecham Plc | Novel compounds |
WO2002022556A1 (fr) * | 2000-09-14 | 2002-03-21 | Mitsubishi Pharma Corporation | Derives amides et utilisations associees |
JP2004529110A (ja) | 2001-03-06 | 2004-09-24 | アストラゼネカ アクチボラグ | 脈管損傷活性を有するインドール誘導体 |
EP1554572B1 (en) | 2001-07-25 | 2009-10-14 | Raptor Pharmaceutical Inc. | Compositions and methods for modulating blood-brain barrier transport |
WO2005041957A1 (en) * | 2003-10-29 | 2005-05-12 | Pfizer Products Inc. | Oxindole derivatives and their use as phosphodiesterase type 2 inhibitors |
AU2006239221C1 (en) | 2005-04-28 | 2012-08-16 | Otsuka Pharmaceutical Co., Ltd. | Pharma-informatics system |
WO2008036682A2 (en) | 2006-09-18 | 2008-03-27 | Raptor Pharmaceutical Inc. | Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates |
ES2728225T3 (es) | 2009-02-20 | 2019-10-23 | 2 Bbb Medicines B V | Sistema de administración de fármacos a base de glutatión |
KR101741629B1 (ko) | 2009-05-06 | 2017-05-31 | 라보라토리 스킨 케어, 인크. | 활성제-칼슘 포스페이트 입자 복합체를 포함하는 피부 전달 조성물 및 이들을 이용하는 방법 |
US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
CN104130176A (zh) * | 2014-06-13 | 2014-11-05 | 天津科技大学 | 一种1,5-二取代吲哚酮类衍生物及其应用 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE756447A (fr) * | 1969-10-15 | 1971-03-22 | Pfizer | Oxindolecarboxamides |
US3749731A (en) * | 1971-07-08 | 1973-07-31 | Warner Lambert Co | 2-oxo-n-(2-thiazolyl)-3-indoline-carboxamide |
DE3114351A1 (de) * | 1981-04-09 | 1982-11-04 | Hoechst Ag, 6000 Frankfurt | "oxindol-derivate, verfahren zu ihrer herstellung und sie enthaltende arzneimittel mit neuroanaboler wirkung" |
AU8509882A (en) * | 1981-06-30 | 1983-01-06 | Merck & Co., Inc. | Tricyclic derivatives of substituted pyrrole acids |
GR850310B (xx) * | 1984-02-07 | 1985-06-05 | Pfizer | |
IE57741B1 (en) * | 1984-03-19 | 1993-03-24 | Pfizer | Process for making 2-oxindole-1-carboxamides and intermediates therefor |
US4556672A (en) * | 1984-03-19 | 1985-12-03 | Pfizer Inc. | 3-Substituted 2-oxindole-1-carboxamides as analgesic and anti-inflammatory agents |
-
1985
- 1985-08-06 US US06/762,998 patent/US4686224A/en not_active Expired - Lifetime
- 1985-10-28 IL IL76854A patent/IL76854A/xx not_active IP Right Cessation
- 1985-10-29 EP EP85307794A patent/EP0181136B1/en not_active Expired - Lifetime
- 1985-10-29 PT PT81393A patent/PT81393B/pt not_active IP Right Cessation
- 1985-10-29 PL PL1985262327A patent/PL150842B1/pl unknown
- 1985-10-29 DE DE8585307794T patent/DE3585719D1/de not_active Expired - Fee Related
- 1985-10-29 PL PL1985255990A patent/PL145239B1/pl unknown
- 1985-10-30 HU HU854158A patent/HU194168B/hu not_active IP Right Cessation
- 1985-10-30 CA CA000494220A patent/CA1247099A/en not_active Expired
- 1985-10-30 DK DK497685A patent/DK163990C/da active
- 1985-10-30 AU AU49189/85A patent/AU555051B2/en not_active Ceased
- 1985-10-30 KR KR1019850008037A patent/KR870001269B1/ko not_active IP Right Cessation
- 1985-10-30 FI FI854258A patent/FI81340C/fi not_active IP Right Cessation
- 1985-10-31 PH PH33000A patent/PH20985A/en unknown
- 1985-10-31 GR GR852629A patent/GR852629B/el unknown
- 1985-11-01 IE IE270385A patent/IE58207B1/en not_active IP Right Cessation
-
1986
- 1986-04-30 ES ES554609A patent/ES8707731A1/es not_active Expired
- 1986-12-05 PH PH34563A patent/PH24091A/en unknown
- 1986-12-05 PH PH34562A patent/PH23130A/en unknown
Also Published As
Publication number | Publication date |
---|---|
DK497685D0 (da) | 1985-10-30 |
PT81393A (en) | 1985-11-01 |
DK497685A (da) | 1986-05-01 |
EP0181136B1 (en) | 1992-03-25 |
ES554609A0 (es) | 1987-08-16 |
ES8707731A1 (es) | 1987-08-16 |
PH24091A (en) | 1990-03-05 |
PT81393B (pt) | 1988-02-17 |
PL262327A1 (en) | 1987-11-02 |
FI81340C (fi) | 1990-10-10 |
AU555051B2 (en) | 1986-09-11 |
PL145239B1 (en) | 1988-08-31 |
PL255990A1 (en) | 1987-03-23 |
FI854258L (fi) | 1986-05-01 |
HU194168B (en) | 1988-01-28 |
FI81340B (fi) | 1990-06-29 |
EP0181136A3 (en) | 1987-10-28 |
PL150842B1 (en) | 1990-07-31 |
KR860003260A (ko) | 1986-05-21 |
PH23130A (en) | 1989-05-05 |
DK163990B (da) | 1992-04-27 |
IE852703L (en) | 1986-04-30 |
IE58207B1 (en) | 1993-07-28 |
FI854258A0 (fi) | 1985-10-30 |
CA1247099A (en) | 1988-12-20 |
IL76854A0 (en) | 1986-02-28 |
PH20985A (en) | 1987-06-18 |
GR852629B (xx) | 1986-03-04 |
AU4918985A (en) | 1986-05-08 |
DE3585719D1 (de) | 1992-04-30 |
HUT39428A (en) | 1986-09-29 |
EP0181136A2 (en) | 1986-05-14 |
DK163990C (da) | 1992-09-21 |
US4686224A (en) | 1987-08-11 |
KR870001269B1 (ko) | 1987-06-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RH | Patent void |