IL67623A - 1'-ethoxycarbonyloxyethyl ester of valproic acid,its preparation and pharmaceutical compositions containing it - Google Patents
1'-ethoxycarbonyloxyethyl ester of valproic acid,its preparation and pharmaceutical compositions containing itInfo
- Publication number
- IL67623A IL67623A IL67623A IL6762383A IL67623A IL 67623 A IL67623 A IL 67623A IL 67623 A IL67623 A IL 67623A IL 6762383 A IL6762383 A IL 6762383A IL 67623 A IL67623 A IL 67623A
- Authority
- IL
- Israel
- Prior art keywords
- valproic acid
- preparation
- pharmaceutical compositions
- compositions containing
- ethoxycarbonyloxyethyl ester
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C68/00—Preparation of esters of carbonic or haloformic acids
- C07C68/06—Preparation of esters of carbonic or haloformic acids from organic carbonates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/96—Esters of carbonic or haloformic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
Priority Applications (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL67623A IL67623A (en) | 1983-01-05 | 1983-01-05 | 1'-ethoxycarbonyloxyethyl ester of valproic acid,its preparation and pharmaceutical compositions containing it |
CA000441017A CA1284152C (en) | 1983-01-05 | 1983-11-14 | 1'-ethoxycarbonyloxyethyl ester of valproic acid, its preparation and pharmaceutical compositions containing it |
AU21421/83A AU558445B2 (en) | 1983-01-05 | 1983-11-16 | 1:-ethoxycarbonyloxyethyl ester of valproic acid |
US06/552,336 US4595695A (en) | 1983-01-05 | 1983-11-16 | 1'-ethoxycarbonyloxyethyl ester of valproic acid, its preparation and pharmaceutical compositions containing it |
ZA838666A ZA838666B (en) | 1983-01-05 | 1983-11-21 | 1'-ethoxycarbonyloxyethyl ester of valproic acid,its preparation and pharmaceutical compositions containing it |
JP58238999A JPS59128359A (ja) | 1983-01-05 | 1983-12-20 | バルブロイツクアシツドの1′−エトキシカルボニルオキシエチルエステル、その製造方法、およびそのエステルを含有する抗てんかん用薬剤 |
AT84300049T ATE18197T1 (de) | 1983-01-05 | 1984-01-05 | 1'-aethoxycarbonyloxyaethylester der valponsaeure, seine herstellung und diesen enthaltende formulierungen. |
DE8484300049T DE3460035D1 (en) | 1983-01-05 | 1984-01-05 | 1'-ethoxycarbonyloxyethyl ester of valproic acid, its preparation and formulations containing it |
EP84300049A EP0114720B1 (en) | 1983-01-05 | 1984-01-05 | 1'-ethoxycarbonyloxyethyl ester of valproic acid, its preparation and formulations containing it |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL67623A IL67623A (en) | 1983-01-05 | 1983-01-05 | 1'-ethoxycarbonyloxyethyl ester of valproic acid,its preparation and pharmaceutical compositions containing it |
Publications (2)
Publication Number | Publication Date |
---|---|
IL67623A0 IL67623A0 (en) | 1983-05-15 |
IL67623A true IL67623A (en) | 1984-09-30 |
Family
ID=11053985
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL67623A IL67623A (en) | 1983-01-05 | 1983-01-05 | 1'-ethoxycarbonyloxyethyl ester of valproic acid,its preparation and pharmaceutical compositions containing it |
Country Status (9)
Country | Link |
---|---|
US (1) | US4595695A (xx) |
EP (1) | EP0114720B1 (xx) |
JP (1) | JPS59128359A (xx) |
AT (1) | ATE18197T1 (xx) |
AU (1) | AU558445B2 (xx) |
CA (1) | CA1284152C (xx) |
DE (1) | DE3460035D1 (xx) |
IL (1) | IL67623A (xx) |
ZA (1) | ZA838666B (xx) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL67623A (en) * | 1983-01-05 | 1984-09-30 | Teva Pharma | 1'-ethoxycarbonyloxyethyl ester of valproic acid,its preparation and pharmaceutical compositions containing it |
IT1190133B (it) * | 1986-06-19 | 1988-02-10 | Chiesi Farma Spa | Derivati di acido valproico e di acido (e)-2-valproenoico,procedimento per la loro preparazione e relative composizioni farmaceutiche |
AU2003217791A1 (en) | 2002-02-28 | 2003-09-16 | A And D Bioscience, Inc. | Glycuronamides, glycosides and orthoester glycosides of fluoxetine, analogs and uses thereof |
US20050107310A1 (en) * | 2002-03-19 | 2005-05-19 | Holick Michael F. | Carboxylic acid glycuronides, glycosamides and glycosides of quinolones, penicillins, analogs, and uses thereof |
US20050255038A1 (en) * | 2002-04-12 | 2005-11-17 | A And D Bioscience, Inc. | Conjugates comprising cancer cell specific ligands, a sugar and diagnostic agents and uses thereof |
CA2484891A1 (en) * | 2002-05-07 | 2003-11-20 | A & D Bioscience, Inc. | Conjugates comprising central nervous system active drug |
US20050215487A1 (en) * | 2002-06-27 | 2005-09-29 | Holick Michael F | Conjugates comprising an nsaid and a sugar and uses thereof |
CN1829804A (zh) | 2002-11-22 | 2006-09-06 | 约翰斯·霍普金斯大学 | 治疗认知功能障碍的靶位 |
EP1928807A4 (en) * | 2005-09-02 | 2011-05-04 | Picobella Llc | ONCOGENIC REGULATORS RNA FOR DIAGNOSIS AND THERAPY |
US7459280B2 (en) * | 2006-02-27 | 2008-12-02 | Picobella, Llc | Methods for diagnosing and treating kidney cancer |
US7763650B2 (en) * | 2006-03-15 | 2010-07-27 | Medipharma S.A. | Pharmaceutical compound and method |
US20080267977A1 (en) * | 2007-04-26 | 2008-10-30 | Friedrich-Alexander University Of Erlangen-Nuremberg | Combined immunological agent and sensitizing agent for the treatment of cancer |
EA033130B1 (ru) | 2008-10-16 | 2019-08-30 | Дзе Джонс Хопкинс Юниверсити | Способы и композиции для улучшения когнитивной функции |
US20110212928A1 (en) * | 2010-02-09 | 2011-09-01 | The Johns Hopkins University | Methods and compositions for improving cognitive function |
AU2013257710B2 (en) * | 2012-05-08 | 2016-10-20 | Cellixbio Private Limited | Compositions and methods for the treatment of neurological disorders |
EP2919788A4 (en) | 2012-11-14 | 2016-05-25 | Univ Johns Hopkins | METHODS AND COMPOSITIONS FOR THE TREATMENT OF SCHIZOPHRENIA |
ES2881081T3 (es) | 2013-03-15 | 2021-11-26 | Agenebio Inc | Procedimientos y composiciones para mejorar la función cognitiva |
US10806717B2 (en) | 2013-03-15 | 2020-10-20 | The Johns Hopkins University | Methods and compositions for improving cognitive function |
JP6899043B2 (ja) | 2015-05-22 | 2021-07-07 | エージンバイオ, インコーポレイテッド | レベチラセタムの持続放出性医薬組成物 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2442M (fr) * | 1962-10-17 | 1964-04-06 | Henry Eugene | L'acide dipropylacétique et ses dérivés en tant que nouveuax médicaments dépresseurs du systeme nerveux central. |
US3646201A (en) * | 1969-07-31 | 1972-02-29 | Liggett & Myers Inc | Salicylate carbonate compounds |
GB1598568A (en) * | 1977-04-19 | 1981-09-23 | Glaxo Lab Ltd | Esters of(6r,7r)-3-carbamoyloxymethyl-7-((z)-2-(fur-2-yl)-2-methoxyiminoacetamido)-ceph-3-em-4-carboxylic acid |
EP0079872B1 (en) * | 1981-11-17 | 1985-03-20 | KabiVitrum AB | Antifibrinolytically active compounds |
US4542158A (en) * | 1981-12-21 | 1985-09-17 | Merck & Co., Inc. | Prodrug esters of diflunisal and related compounds |
NZ202721A (en) * | 1981-12-21 | 1985-12-13 | Merck & Co Inc | Diflunisal derivatives and pharmaceutical compositions |
US4426391A (en) * | 1982-09-15 | 1984-01-17 | Merck & Co., Inc. | [(Alkoxycarbonyl)oxy]alkyl esters of methyldopa |
IL67445A (en) * | 1982-12-09 | 1985-11-29 | Teva Pharma | Ethoxycarbonyloxy ethyl esters of non-steroidal anti-inflammatory carboxylic acids |
IL67623A (en) * | 1983-01-05 | 1984-09-30 | Teva Pharma | 1'-ethoxycarbonyloxyethyl ester of valproic acid,its preparation and pharmaceutical compositions containing it |
-
1983
- 1983-01-05 IL IL67623A patent/IL67623A/xx unknown
- 1983-11-14 CA CA000441017A patent/CA1284152C/en not_active Expired - Lifetime
- 1983-11-16 US US06/552,336 patent/US4595695A/en not_active Expired - Fee Related
- 1983-11-16 AU AU21421/83A patent/AU558445B2/en not_active Ceased
- 1983-11-21 ZA ZA838666A patent/ZA838666B/xx unknown
- 1983-12-20 JP JP58238999A patent/JPS59128359A/ja active Granted
-
1984
- 1984-01-05 DE DE8484300049T patent/DE3460035D1/de not_active Expired
- 1984-01-05 AT AT84300049T patent/ATE18197T1/de not_active IP Right Cessation
- 1984-01-05 EP EP84300049A patent/EP0114720B1/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
CA1284152C (en) | 1991-05-14 |
JPS59128359A (ja) | 1984-07-24 |
AU558445B2 (en) | 1987-01-29 |
ZA838666B (en) | 1984-07-25 |
AU2142183A (en) | 1984-07-12 |
EP0114720B1 (en) | 1986-02-26 |
IL67623A0 (en) | 1983-05-15 |
DE3460035D1 (en) | 1986-04-03 |
EP0114720A1 (en) | 1984-08-01 |
JPS6229423B2 (xx) | 1987-06-25 |
US4595695A (en) | 1986-06-17 |
ATE18197T1 (de) | 1986-03-15 |
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