IL66245A - Antibacterial 3-phenoxy or-thienyloxy penem derivatives,their preparation and pharmaceutical compositions comprising them - Google Patents

Antibacterial 3-phenoxy or-thienyloxy penem derivatives,their preparation and pharmaceutical compositions comprising them

Info

Publication number
IL66245A
IL66245A IL66245A IL6624582A IL66245A IL 66245 A IL66245 A IL 66245A IL 66245 A IL66245 A IL 66245A IL 6624582 A IL6624582 A IL 6624582A IL 66245 A IL66245 A IL 66245A
Authority
IL
Israel
Prior art keywords
thienyloxy
phenoxy
antibacterial
preparation
pharmaceutical compositions
Prior art date
Application number
IL66245A
Other languages
English (en)
Other versions
IL66245A0 (en
Original Assignee
Hoechst Uk Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Uk Ltd filed Critical Hoechst Uk Ltd
Publication of IL66245A0 publication Critical patent/IL66245A0/xx
Publication of IL66245A publication Critical patent/IL66245A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL66245A 1981-07-08 1982-07-06 Antibacterial 3-phenoxy or-thienyloxy penem derivatives,their preparation and pharmaceutical compositions comprising them IL66245A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8121108 1981-07-08
GB8207136 1982-03-11

Publications (2)

Publication Number Publication Date
IL66245A0 IL66245A0 (en) 1982-11-30
IL66245A true IL66245A (en) 1988-05-31

Family

ID=26280061

Family Applications (1)

Application Number Title Priority Date Filing Date
IL66245A IL66245A (en) 1981-07-08 1982-07-06 Antibacterial 3-phenoxy or-thienyloxy penem derivatives,their preparation and pharmaceutical compositions comprising them

Country Status (13)

Country Link
US (2) US4585767A (es)
EP (1) EP0069377B1 (es)
KR (1) KR890001885B1 (es)
AU (4) AU562008B2 (es)
CA (1) CA1225392A (es)
DE (1) DE3278689D1 (es)
ES (3) ES8305366A1 (es)
FI (1) FI77661C (es)
GB (2) GB2102798B (es)
GR (1) GR75500B (es)
IE (1) IE54585B1 (es)
IL (1) IL66245A (es)
PT (1) PT75197B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0185651A1 (en) * 1981-07-08 1986-06-25 Hoechst Uk Limited Intermediates for the production of antibacterial penem derivates
GR78890B (es) * 1982-07-08 1984-10-02 Hoechst Uk Ltd
US4595539A (en) * 1983-06-10 1986-06-17 Pfizer Inc. Preparation of penem derivatives and azetidinone intermediates
US4725678A (en) * 1983-06-10 1988-02-16 Pfizer Inc. Azetidinone intermediates for the preparation of penem derivatives
US4619783A (en) * 1983-06-10 1986-10-28 Pfizer Inc. Process and intermediates for the preparation of penem derivatives
GB2197864B (en) * 1984-06-29 1989-05-17 Hoechst Uk Ltd Antibacterial 7-oxo-4-thia-1-azabicyclo(3.2.0)-hept-2-ene derivatives
GB8416565D0 (en) * 1984-06-29 1984-08-01 Hoechst Uk Ltd Antibacterial derivatives
GB2197865B (en) * 1984-06-29 1989-05-17 Hoechst Uk Ltd Azetidinone derivatives
GB2164334B (en) * 1984-09-10 1988-08-03 Hoechst Uk Ltd Antibacterial 7-oxo-4-thia-1-azabicyclo 3,2,0 hept-2-ene derivativess
GB8605549D0 (en) * 1986-03-06 1986-04-09 Erba Farmitalia Penem derivatives
DE3618813A1 (de) * 1986-06-04 1987-12-10 Hoechst Ag Pharmazeutische zubereitung zur behandlung bakterieller infektionen
GB2195627A (en) * 1986-08-12 1988-04-13 Hoechst Uk Ltd Penem derivatives
AT392903B (de) * 1987-10-08 1991-07-10 Hoechst Ag Pharmazeutische zubereitung enthaltend ein cephalosporin und ein penemantibiotikum
US5075439A (en) * 1990-08-17 1991-12-24 Pfizer Inc. Processes for (3S,4R)-3-[1(R)-t-butyl-dimethylsilyloxy)-ethyl]-4-[1-oxo-3-thiolanylthio(thiocarbonyl)thio]azetidin-2-ones and intermediates therefor

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU77306A1 (es) * 1977-05-09 1979-01-18
US4168314A (en) * 1977-11-17 1979-09-18 Merck & Co., Inc. 6-(1'-Hydroxyethyl)-2-aminoethylthio-pen-2-em-3-carboxylic acid
JPS5625110A (en) * 1978-12-18 1981-03-10 Bristol Myers Co Antibacterial
US4293555A (en) * 1979-04-17 1981-10-06 Merck & Co., Inc. 6- and 6,6-Disubstituted-2-substituted-oxapen-2-em-3-carboxylic acids
JPS56115788A (en) * 1980-02-19 1981-09-11 Sankyo Co Ltd Azetidinone derivative and its preparation
EP0051813B1 (en) * 1980-11-06 1986-07-30 Hoechst Uk Limited 7-oxo-4-thia-1-aza(3,2,0)heptane and 7-oxo-4-thia-1-aza(3,2,0)hept-2-ene derivatives
US4347183A (en) * 1981-02-02 1982-08-31 Schering Corporation Process for the synthesis of penems and carbapenems

Also Published As

Publication number Publication date
GB2102798B (en) 1985-12-11
CA1225392A (en) 1987-08-11
AU7097287A (en) 1987-08-27
US4585767A (en) 1986-04-29
DE3278689D1 (en) 1988-07-28
KR840000557A (ko) 1984-02-25
ES513672A0 (es) 1983-04-01
AU562008B2 (en) 1987-05-28
EP0069377A3 (en) 1983-04-13
ES516863A0 (es) 1984-01-16
FI822401A0 (fi) 1982-07-06
GR75500B (es) 1984-07-24
IE54585B1 (en) 1989-12-06
EP0069377B1 (en) 1988-06-22
KR890001885B1 (ko) 1989-05-29
PT75197B (en) 1985-01-07
AU8570282A (en) 1983-01-13
PT75197A (en) 1982-08-01
FI77661B (fi) 1988-12-30
GB2102798A (en) 1983-02-09
GB2151630B (en) 1986-02-12
GB8500841D0 (en) 1985-02-20
ES8305366A1 (es) 1983-04-01
US4772692A (en) 1988-09-20
FI822401L (fi) 1983-01-09
ES516864A0 (es) 1983-09-16
ES8308567A1 (es) 1983-09-16
AU7097387A (en) 1987-08-27
GB2151630A (en) 1985-07-24
FI77661C (fi) 1989-04-10
IE821641L (en) 1983-01-08
EP0069377A2 (en) 1983-01-12
ES8402309A1 (es) 1984-01-16
IL66245A0 (en) 1982-11-30
AU7097487A (en) 1987-08-27

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