IL60422A - Formylhydroxyphenoxy pentanoic and methylbenzoic acids and derivatives thereof,their preparation and pharmaceutical compositions containing them - Google Patents

Formylhydroxyphenoxy pentanoic and methylbenzoic acids and derivatives thereof,their preparation and pharmaceutical compositions containing them

Info

Publication number: IL60422A
Authority: IL; Israel
Prior art keywords: formylhydroxyphenoxy; pentanoic; derivatives; preparation; pharmaceutical compositions
Prior art date: 1979-06-29

Application number

IL60422A

Other languages

English (en)

Other versions

IL60422A0 (en

Original Assignee

Wellcome Found

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1979-06-29

Filing date

1980-06-27

Publication date

1984-06-29

1980-06-27 Application filed by Wellcome Found filed Critical Wellcome Found

1980-09-16 Publication of IL60422A0 publication Critical patent/IL60422A0/xx

1984-06-29 Publication of IL60422A publication Critical patent/IL60422A/xx

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/125—Saturated compounds having only one carboxyl group and containing ether groups, groups, groups, or groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C65/30—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing —CHO groups
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/74—Unsaturated compounds containing —CHO groups

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Hematology (AREA)
Diabetes (AREA)
Pulmonology (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)

IL60422A 1979-06-29 1980-06-27 Formylhydroxyphenoxy pentanoic and methylbenzoic acids and derivatives thereof,their preparation and pharmaceutical compositions containing them IL60422A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB7922781		1979-06-29

Publications (2)

Publication Number	Publication Date
IL60422A0 IL60422A0 (en)	1980-09-16
IL60422A true IL60422A (en)	1984-06-29

Family

ID=10506199

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL60422A IL60422A (en)	1979-06-29	1980-06-27	Formylhydroxyphenoxy pentanoic and methylbenzoic acids and derivatives thereof,their preparation and pharmaceutical compositions containing them

Country Status (18)

Country	Link
US (1)	US4410537A (ja)
EP (1)	EP0022229B1 (ja)
JP (1)	JPS5649335A (ja)
KR (2)	KR850000073B1 (ja)
AU (1)	AU545274B2 (ja)
DE (1)	DE3061269D1 (ja)
DK (1)	DK159770C (ja)
FI (1)	FI71929C (ja)
GB (1)	GB2053218B (ja)
GR (1)	GR68748B (ja)
HU (1)	HU190774B (ja)
IL (1)	IL60422A (ja)
IT (1)	IT1133025B (ja)
MW (1)	MW2380A1 (ja)
OA (1)	OA06699A (ja)
ZA (1)	ZA803880B (ja)
ZM (1)	ZM5780A1 (ja)
ZW (1)	ZW14480A1 (ja)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HU190371B (en) *	1980-12-18	1986-08-28	The Wellcome Foundation Ltd,Gb	Process for producing ether-type compounds and pharmaceutical compositions containing them as active agents
GB8606913D0 (en) *	1986-03-20	1986-04-23	Hider R C	Treatment of sickle cell disease
WO1998030141A2 (en)	1997-01-09	1998-07-16	Cohesion Technologies, Inc.	Devices for tissue repair and methods for preparation and use thereof
US7129274B1 (en)	1999-11-05	2006-10-31	Emisphere Technologies Inc.	Phenoxy carboxylic acid compounds and compositions for delivering active agents
JP5117658B2 (ja) *	1999-11-05	2013-01-16	エミスフェアー・テクノロジーズ・インク	フェノキシカルボン酸化合物及び活性剤を送達するための組成物
US7279597B1 (en)	1999-11-05	2007-10-09	Emisphere Technologies, Inc.	Phenyl amine carboxylic acid compounds and compositions for delivering active agents
AU2001245823A1 (en) *	2000-03-17	2001-10-03	Corixa Corporation	Novel amphipathic aldehydes and their use as adjuvants and immunoeffectors
US8246969B2 (en)	2001-11-16	2012-08-21	Skinmedica, Inc.	Compositions containing aromatic aldehydes and their use in treatments
AU2012204164A1 (en)	2011-01-07	2013-07-25	Allergan, Inc.	Melanin modification compositions and methods of use
PT3738434T (pt)	2011-12-28	2023-11-13	Global Blood Therapeutics Inc	Intermediários para obter compostos de benzaldeído substituído e métodos para a sua utilização no aumento da oxigenação de tecidos
ES2790358T3 (es)	2011-12-28	2020-10-27	Global Blood Therapeutics Inc	Compuestos de heteroaril aldehído sustituido y métodos para su uso en el aumento de la oxigenación tisular
US10266551B2 (en)	2013-03-15	2019-04-23	Global Blood Therapeutics, Inc.	Compounds and uses thereof for the modulation of hemoglobin
CA2902711C (en)	2013-03-15	2021-07-06	Global Blood Therapeutics, Inc.	Substituted pyridinyl-6-methoxy-2-hydroxybenzaldehyde derivatives and pharmaceutical compositions thereof useful for the modulation of hemoglobin
US8952171B2 (en)	2013-03-15	2015-02-10	Global Blood Therapeutics, Inc.	Compounds and uses thereof for the modulation of hemoglobin
US9604999B2 (en)	2013-03-15	2017-03-28	Global Blood Therapeutics, Inc.	Compounds and uses thereof for the modulation of hemoglobin
US9802900B2 (en)	2013-03-15	2017-10-31	Global Blood Therapeutics, Inc.	Bicyclic heteroaryl compounds and uses thereof for the modulation of hemoglobin
CN111454200A (zh)	2013-03-15	2020-07-28	全球血液疗法股份有限公司	化合物及其用于调节血红蛋白的用途
SG10201802911RA (en) *	2013-03-15	2018-05-30	Global Blood Therapeutics Inc	Compounds and uses thereof for the modulation of hemoglobin
US10100043B2 (en)	2013-03-15	2018-10-16	Global Blood Therapeutics, Inc.	Substituted aldehyde compounds and methods for their use in increasing tissue oxygenation
US9458139B2 (en)	2013-03-15	2016-10-04	Global Blood Therapeutics, Inc.	Compounds and uses thereof for the modulation of hemoglobin
US20140274961A1 (en)	2013-03-15	2014-09-18	Global Blood Therapeutics, Inc.	Compounds and uses thereof for the modulation of hemoglobin
US9422279B2 (en)	2013-03-15	2016-08-23	Global Blood Therapeutics, Inc.	Compounds and uses thereof for the modulation of hemoglobin
EP3036222A2 (en) *	2013-08-23	2016-06-29	Virginia Commonwealth University	Ester nitrates derivatives of aromatic aldehydes with multiple pharmalogic properties to treat sickle cell disease
EA201992707A1 (ru)	2013-11-18	2020-06-30	Глобал Блад Терапьютикс, Инк.	Соединения и их применения для модуляции гемоглобина
SI3102208T1 (sl)	2014-02-07	2021-07-30	Global Blood Therapeutics, Inc.	Kristalinični polimorf proste baze 2-hidroksi-6-((2-(1-izopropil-1H-pirazol-5-IL)piridin-3-IL)metoksi)- benzaldehida
MY190034A (en)	2015-03-06	2022-03-22	Beyondspring Pharmaceuticals Inc	Method of treating cancer associated with a ras mutation
MA41841A (fr)	2015-03-30	2018-02-06	Global Blood Therapeutics Inc	Composés aldéhyde pour le traitement de la fibrose pulmonaire, de l'hypoxie, et de maladies auto-immunes et des tissus conjonctifs
MA43373A (fr)	2015-12-04	2018-10-10	Global Blood Therapeutics Inc	Régimes posologiques pour 2-hydroxy-6-((2- (1-isopropyl-1h-pyrazol-5-yl)pyridin-3-yl)méthoxy)benzaldéhyde
MY192703A (en) *	2016-02-08	2022-09-02	Beyondspring Pharmaceuticals Inc	Compositions containing tucaresol or its analogs
TWI752307B (zh)	2016-05-12	2022-01-11	美商全球血液治療公司	新穎化合物及製造化合物之方法
TWI778983B (zh)	2016-10-12	2022-10-01	美商全球血液治療公司	包含2-羥基-6-((2-(1-異丙基-1h-吡唑-5-基)吡啶-3-基)甲氧基)-苯甲醛之片劑
EP3768264A4 (en) *	2018-03-22	2021-12-22	Virginia Commonwealth University	AROMATIC ALDEHYDE WITH DELAYED AND IMPROVED PHARMACOLOGICAL IN-VITRO AND IN-VIVO ACTIVITY FOR TREATMENT OF SICKLE CELL DISEASE
US11014884B2 (en)	2018-10-01	2021-05-25	Global Blood Therapeutics, Inc.	Modulators of hemoglobin
JP2022509091A (ja)	2018-11-19	2022-01-20	グローバルブラッドセラピューティクスインコーポレイテッド	ヘモグロビンのモジュレーター

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
LU36787A1 (ja) *	1958-04-30
CH543472A (fr) *	1969-01-31	1973-10-31	Orchimed Sa	Procédé pour la préparation d'acides phénoxyalcoyl-carboxyliques
DE2209128C3 (de)	1971-03-05	1981-10-22	CIBA-GEIGY AG, 4002 Basel	Bis-Stilbenverbindungen, Verfahren zu deren Herstellung und deren Verwendung als optische Aufheller
CH550776A (de)	1971-03-05	1974-06-28	Ciba Geigy Ag	Herstellung neuer bis-stilbenverbindungen.
GB1511645A (en)	1974-05-31	1978-05-24	Univ Ife	Sickle cell anaemia treatment
US4137309A (en) *	1976-10-14	1979-01-30	The Procter & Gamble Company	Therapeutic treatment

1980
- 1980-06-27 GB GB8021219A patent/GB2053218B/en not_active Expired
- 1980-06-27 ZW ZW144/80A patent/ZW14480A1/xx unknown
- 1980-06-27 MW MW23/80A patent/MW2380A1/xx unknown
- 1980-06-27 DK DK279780A patent/DK159770C/da not_active IP Right Cessation
- 1980-06-27 ZM ZM57/80A patent/ZM5780A1/xx unknown
- 1980-06-27 EP EP80103657A patent/EP0022229B1/en not_active Expired
- 1980-06-27 FI FI802052A patent/FI71929C/fi not_active IP Right Cessation
- 1980-06-27 KR KR1019800002541A patent/KR850000073B1/ko active
- 1980-06-27 AU AU59697/80A patent/AU545274B2/en not_active Ceased
- 1980-06-27 GR GR62311A patent/GR68748B/el unknown
- 1980-06-27 ZA ZA00803880A patent/ZA803880B/xx unknown
- 1980-06-27 IL IL60422A patent/IL60422A/xx not_active IP Right Cessation
- 1980-06-27 DE DE8080103657T patent/DE3061269D1/de not_active Expired
- 1980-06-27 HU HU801601A patent/HU190774B/hu not_active IP Right Cessation
- 1980-06-27 JP JP8764580A patent/JPS5649335A/ja active Granted
- 1980-06-27 IT IT49108/80A patent/IT1133025B/it active
- 1980-08-09 OA OA57193A patent/OA06699A/xx unknown
1981
- 1981-06-09 US US06/271,950 patent/US4410537A/en not_active Expired - Lifetime
1984
- 1984-03-13 KR KR1019840001263A patent/KR850000072B1/ko not_active IP Right Cessation

Also Published As

Publication number	Publication date
KR830002693A (ko)	1983-05-30
GB2053218A (en)	1981-02-04
ZM5780A1 (en)	1983-11-21
DK279780A (da)	1980-12-30
JPS5649335A (en)	1981-05-02
MW2380A1 (en)	1982-03-10
HU190774B (en)	1986-11-28
DK159770B (da)	1990-12-03
DE3061269D1 (en)	1983-01-13
ZA803880B (en)	1982-02-24
KR850000072B1 (ko)	1985-02-18
IT1133025B (it)	1986-07-09
KR850000073B1 (ko)	1985-02-18
GR68748B (ja)	1982-02-16
AU545274B2 (en)	1985-07-11
KR840004668A (ko)	1984-10-22
EP0022229B1 (en)	1982-12-08
AU5969780A (en)	1981-01-08
IL60422A0 (en)	1980-09-16
OA06699A (fr)	1982-05-31
EP0022229A1 (en)	1981-01-14
JPH0154339B2 (ja)	1989-11-17
FI802052A (fi)	1980-12-30
ZW14480A1 (en)	1982-03-17
IT8049108A0 (it)	1980-06-27
GB2053218B (en)	1984-01-25
DK159770C (da)	1991-04-22
FI71929B (fi)	1986-11-28
FI71929C (fi)	1987-03-09
US4410537A (en)	1983-10-18

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Legal Events

Date	Code	Title	Description
1999-06-20	RH	Patent void