IL54813A - 11-(4-substituted piperazinyl)acetyl)-5,11-dihydro-6h-pyrido(2,3-b)(1,4)benzodiazepin-6-one derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

11-(4-substituted piperazinyl)acetyl)-5,11-dihydro-6h-pyrido(2,3-b)(1,4)benzodiazepin-6-one derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number: IL54813A
Authority: IL; Israel
Prior art keywords: benzodiazepin; pyrido; dihydro; acetyl; derivatives
Prior art date: 1977-05-31

Application number

IL54813A

Other languages

English (en)

Other versions

IL54813A0 (en

Original Assignee

Thomae Gmbh Dr K

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1977-05-31

Filing date

1978-05-30

Publication date

1982-02-28

1978-05-30 Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K

1978-07-31 Publication of IL54813A0 publication Critical patent/IL54813A0/xx

1982-02-28 Publication of IL54813A publication Critical patent/IL54813A/xx

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

IL54813A 1977-05-31 1978-05-30 11-(4-substituted piperazinyl)acetyl)-5,11-dihydro-6h-pyrido(2,3-b)(1,4)benzodiazepin-6-one derivatives,their preparation and pharmaceutical compositions containing them IL54813A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19772724434 DE2724434A1 (de)	1977-05-31	1977-05-31	Neue, in 11-stellung substituierte 5,11-dihydro-6h-pyrido eckige klammer auf 2,3-b eckige klammer zu eckige klammer auf 1,4 eckige klammer zu benzodiazepin-6-one, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Publications (2)

Publication Number	Publication Date
IL54813A0 IL54813A0 (en)	1978-07-31
IL54813A true IL54813A (en)	1982-02-28

Family

ID=6010263

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL54813A IL54813A (en)	1977-05-31	1978-05-30	11-(4-substituted piperazinyl)acetyl)-5,11-dihydro-6h-pyrido(2,3-b)(1,4)benzodiazepin-6-one derivatives,their preparation and pharmaceutical compositions containing them

Country Status (31)

Country	Link
US (1)	US4213984A (ru)
JP (1)	JPS543096A (ru)
AT (1)	AT361491B (ru)
AU (1)	AU516893B2 (ru)
BE (1)	BE867638A (ru)
BG (2)	BG28711A3 (ru)
CA (1)	CA1109064A (ru)
CH (1)	CH637652A5 (ru)
CS (1)	CS207617B2 (ru)
DD (1)	DD137106A5 (ru)
DE (1)	DE2724434A1 (ru)
DK (1)	DK239578A (ru)
ES (2)	ES470270A1 (ru)
FI (1)	FI63232C (ru)
FR (1)	FR2392993A1 (ru)
GB (1)	GB1571781A (ru)
GR (1)	GR66164B (ru)
HK (1)	HK11182A (ru)
HU (1)	HU180999B (ru)
IE (1)	IE46907B1 (ru)
IL (1)	IL54813A (ru)
MY (1)	MY8200242A (ru)
NL (1)	NL7805847A (ru)
NO (1)	NO149313C (ru)
NZ (1)	NZ187426A (ru)
PH (1)	PH14609A (ru)
PL (2)	PL112911B1 (ru)
PT (1)	PT68112A (ru)
SE (1)	SE7806288L (ru)
SU (1)	SU772484A3 (ru)
ZA (1)	ZA783084B (ru)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB2053187A (en) *	1979-07-09	1981-02-04	Grissmann Chem Ltd	Process for preparing pyrenzepine
IT1130973B (it) *	1980-03-17	1986-06-18	Microsules Argentina Sa De S C	Processo per la preparazione di derivati di 5,11-di-idro-6h-pirido(2,3-b) (1,4)-benzodiazepin-6-one,derivati finali ed intermedi di sintesi in tal modo ottenuti
DE3204401A1 (de) *	1982-02-09	1983-08-11	Dr. Karl Thomae Gmbh, 7950 Biberach	Pyridobenzodiazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3204403A1 (de) *	1982-02-09	1983-08-11	Dr. Karl Thomae Gmbh, 7950 Biberach	Neue pyridobenzodiazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
IT1212742B (it) *	1983-05-17	1989-11-30	Dompe Farmaceutici Spa	Derivati dibenzo [1,4]diazepinonici pirido [1,4] benzodiazepinonici,pirido [1,5] benzodiazepinonici e loro attivita' farmacologica
DE3726908A1 (de) *	1987-08-13	1989-02-23	Thomae Gmbh Dr K	Neue kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3820345A1 (de) *	1988-06-15	1989-12-21	Thomae Gmbh Dr K	Kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US5298508A (en) *	1988-07-19	1994-03-29	The United States Of America As Represented By The Department Of Health And Human Services	Irreversible inhibitors of adenosine receptors
US5324832A (en) *	1991-07-03	1994-06-28	The United States Of America As Represented By The Department Of Health And Human Services	Muscarinic antagonists
US6316423B1 (en)	1996-04-10	2001-11-13	The United States Of America As Represented By The Departmant Of Health And Human Services	Method of treating ischemic, hypoxic and anoxic brain damage
AU2005263577C1 (en)	2004-07-16	2010-08-26	Proteosys Ag	Muscarinic antagonists with PARP and SiR modulating activity as cytoprotective agents
WO2010081825A2 (en)	2009-01-13	2010-07-22	Proteosys Ag	Pirenzepine as an agent in cancer treatment
CN103242246A (zh) *	2013-05-21	2013-08-14	苏州科捷生物医药有限公司	3-位取代的n-甲基哌嗪的合成方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1795183B1 (de) *	1968-08-20	1972-07-20	Thomae Gmbh Dr K	5,11-Dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-on-derivate und Arzneimittel

1977
- 1977-05-31 DE DE19772724434 patent/DE2724434A1/de not_active Withdrawn
1978
- 1978-05-10 FI FI781474A patent/FI63232C/fi not_active IP Right Cessation
- 1978-05-19 US US05/907,888 patent/US4213984A/en not_active Expired - Lifetime
- 1978-05-22 AT AT367878A patent/AT361491B/de not_active IP Right Cessation
- 1978-05-24 DD DD78205555A patent/DD137106A5/xx unknown
- 1978-05-24 GR GR56314A patent/GR66164B/el unknown
- 1978-05-26 GB GB23188/78A patent/GB1571781A/en not_active Expired
- 1978-05-29 CS CS783471A patent/CS207617B2/cs unknown
- 1978-05-29 ES ES470270A patent/ES470270A1/es not_active Expired
- 1978-05-29 IE IE1071/78A patent/IE46907B1/en unknown
- 1978-05-29 CH CH586178A patent/CH637652A5/de not_active IP Right Cessation
- 1978-05-30 AU AU36622/78A patent/AU516893B2/en not_active Expired
- 1978-05-30 NZ NZ187426A patent/NZ187426A/xx unknown
- 1978-05-30 NO NO781878A patent/NO149313C/no unknown
- 1978-05-30 ZA ZA783084A patent/ZA783084B/xx unknown
- 1978-05-30 CA CA304,426A patent/CA1109064A/en not_active Expired
- 1978-05-30 IL IL54813A patent/IL54813A/xx unknown
- 1978-05-30 BE BE188179A patent/BE867638A/xx not_active IP Right Cessation
- 1978-05-30 PL PL1978207191A patent/PL112911B1/pl unknown
- 1978-05-30 DK DK239578A patent/DK239578A/da not_active Application Discontinuation
- 1978-05-30 HU HU78TO1081A patent/HU180999B/hu unknown
- 1978-05-30 PT PT68112A patent/PT68112A/pt unknown
- 1978-05-30 BG BG039908A patent/BG28711A3/xx unknown
- 1978-05-30 JP JP6484478A patent/JPS543096A/ja active Pending
- 1978-05-30 PL PL1978214169A patent/PL113628B1/pl unknown
- 1978-05-30 SE SE7806288A patent/SE7806288L/xx unknown
- 1978-05-30 NL NL7805847A patent/NL7805847A/xx not_active Application Discontinuation
- 1978-05-30 BG BG040725A patent/BG26949A4/xx unknown
- 1978-05-30 SU SU782619956A patent/SU772484A3/ru active
- 1978-05-31 FR FR7816250A patent/FR2392993A1/fr active Granted
- 1978-05-31 PH PH21218A patent/PH14609A/en unknown
- 1978-09-18 ES ES473441A patent/ES473441A1/es not_active Expired
1982
- 1982-03-11 HK HK111/82A patent/HK11182A/xx unknown
- 1982-12-30 MY MY242/82A patent/MY8200242A/xx unknown

Also Published As

Publication number	Publication date
US4213984A (en)	1980-07-22
DD137106A5 (de)	1979-08-15
CH637652A5 (de)	1983-08-15
ES470270A1 (es)	1979-01-01
CA1109064A (en)	1981-09-15
IL54813A0 (en)	1978-07-31
ATA367878A (de)	1980-08-15
NO149313B (no)	1983-12-19
ES473441A1 (es)	1979-05-01
ZA783084B (en)	1980-02-27
SU772484A3 (ru)	1980-10-15
GB1571781A (en)	1980-07-16
DK239578A (da)	1978-12-01
FI63232B (fi)	1983-01-31
AU516893B2 (en)	1981-06-25
PL207191A1 (pl)	1979-07-16
FR2392993A1 (fr)	1978-12-29
BE867638A (fr)	1978-11-30
SE7806288L (sv)	1978-12-01
BG28711A3 (en)	1980-06-16
NO149313C (no)	1984-03-28
AU3662278A (en)	1979-12-06
PH14609A (en)	1981-10-02
NZ187426A (en)	1981-10-19
PL112911B1 (en)	1980-11-29
HU180999B (en)	1983-05-30
PT68112A (de)	1978-06-01
AT361491B (de)	1981-03-10
NO781878L (no)	1978-12-01
IE781071L (en)	1978-11-30
FI781474A (fi)	1978-12-01
MY8200242A (en)	1982-12-31
PL214169A1 (ru)	1979-11-05
FI63232C (fi)	1983-05-10
FR2392993B1 (ru)	1981-06-26
BG26949A4 (bg)	1979-07-12
IE46907B1 (en)	1983-11-02
PL113628B1 (en)	1980-12-31
GR66164B (ru)	1981-01-20
DE2724434A1 (de)	1979-02-22
HK11182A (en)	1982-03-19
CS207617B2 (en)	1981-08-31
JPS543096A (en)	1979-01-11
NL7805847A (nl)	1978-12-04

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