IL52011A - Immunosuppressant pharmaceutical compositions containing 5-aminoalkyl isothiourea or 2-aminoalkyl imidazoline salts and some such novel compounds in the base or salt form - Google Patents

Immunosuppressant pharmaceutical compositions containing 5-aminoalkyl isothiourea or 2-aminoalkyl imidazoline salts and some such novel compounds in the base or salt form

Info

Publication number
IL52011A
IL52011A IL52011A IL5201177A IL52011A IL 52011 A IL52011 A IL 52011A IL 52011 A IL52011 A IL 52011A IL 5201177 A IL5201177 A IL 5201177A IL 52011 A IL52011 A IL 52011A
Authority
IL
Israel
Prior art keywords
aminoalkyl
isothiourea
base
pharmaceutical compositions
compositions containing
Prior art date
Application number
IL52011A
Other languages
English (en)
Original Assignee
Smith Kline French Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith Kline French Lab filed Critical Smith Kline French Lab
Publication of IL52011A publication Critical patent/IL52011A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/30—Isothioureas
    • C07C335/32—Isothioureas having sulfur atoms of isothiourea groups bound to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30—Oxygen or sulfur atoms
    • C07D233/42—Sulfur atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Transplantation (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL52011A 1976-05-14 1977-05-04 Immunosuppressant pharmaceutical compositions containing 5-aminoalkyl isothiourea or 2-aminoalkyl imidazoline salts and some such novel compounds in the base or salt form IL52011A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB19994/76A GB1592453A (en) 1976-05-14 1976-05-14 Aminoalkyl esters of carbarimidothioic acid and compositions having immunosuppressant activity

Publications (1)

Publication Number Publication Date
IL52011A true IL52011A (en) 1982-05-31

Family

ID=10138568

Family Applications (1)

Application Number Title Priority Date Filing Date
IL52011A IL52011A (en) 1976-05-14 1977-05-04 Immunosuppressant pharmaceutical compositions containing 5-aminoalkyl isothiourea or 2-aminoalkyl imidazoline salts and some such novel compounds in the base or salt form

Country Status (23)

Country Link
US (1) US4294854A (xx)
JP (1) JPS532420A (xx)
AR (1) AR218872A1 (xx)
AT (1) AT359521B (xx)
AU (1) AU509573B2 (xx)
BE (1) BE854553A (xx)
CA (1) CA1086758A (xx)
CH (1) CH620203A5 (xx)
DE (1) DE2721830A1 (xx)
DK (1) DK211277A (xx)
ES (1) ES458756A1 (xx)
FI (1) FI771400A (xx)
FR (2) FR2351098A1 (xx)
GB (1) GB1592453A (xx)
HU (1) HU174978B (xx)
IE (1) IE45144B1 (xx)
IL (1) IL52011A (xx)
LU (1) LU77332A1 (xx)
NL (1) NL7705331A (xx)
NO (1) NO771697L (xx)
PT (1) PT66509B (xx)
SE (1) SE7705658L (xx)
ZA (1) ZA772612B (xx)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0672244B2 (ja) * 1984-12-12 1994-09-14 三菱マテリアル株式会社 貴金属造粒装置
WO1994028897A2 (en) * 1993-06-07 1994-12-22 The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services Use of an mhc class i suppressor drug for the treatment of autoimmune diseases and transplantation rejection
AU3230895A (en) * 1994-08-18 1996-03-14 Chugai Seiyaku Kabushiki Kaisha Amino acid derivative having nitrogen monoxide synthetase inhibitor activity
US7645873B2 (en) * 2003-03-20 2010-01-12 The Scripps Research Institute 6″-amino-6″-deoxygalactosylceramides
EP2058011A1 (en) * 2007-11-07 2009-05-13 Wittycell Nkt cell activating gycolipids covalently bound antigens and/or drug
CN102215864A (zh) * 2008-10-08 2011-10-12 威蒂赛尔公司 用于抗流感的疫苗组合物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2648710A (en) * 1950-09-22 1953-08-11 Hoffmann La Roche Bis-quaternary salts of 1:10-bis-(dialkylamino)-5:6-dithia-decane
US2813102A (en) * 1956-04-10 1957-11-12 American Home Prod 2-(di-lower alkylaminoethylmercapto)-imidazolines and their acid addition salts and preparation thereof
US4152453A (en) * 1975-12-01 1979-05-01 Smith Kline & French Laboratories Limited Pharmacologically active compounds and compositions and methods of use

Also Published As

Publication number Publication date
DK211277A (da) 1977-11-15
JPS532420A (en) 1978-01-11
CH620203A5 (xx) 1980-11-14
AU509573B2 (en) 1980-05-15
FR2351098B1 (xx) 1982-06-18
IE45144L (en) 1977-11-14
CA1086758A (en) 1980-09-30
NO771697L (no) 1977-11-15
HU174978B (hu) 1980-04-28
LU77332A1 (xx) 1977-08-29
DE2721830A1 (de) 1977-11-24
ATA318277A (de) 1980-04-15
ZA772612B (en) 1978-04-26
SE7705658L (sv) 1977-11-15
AU2507977A (en) 1978-11-16
ES458756A1 (es) 1978-03-01
IE45144B1 (en) 1982-06-30
FR2472935A1 (fr) 1981-07-10
GB1592453A (en) 1981-07-08
BE854553A (fr) 1977-11-14
FI771400A (xx) 1977-11-15
AT359521B (de) 1980-11-10
US4294854A (en) 1981-10-13
AR218872A1 (es) 1980-07-15
FR2351098A1 (fr) 1977-12-09
NL7705331A (nl) 1977-11-16
PT66509A (en) 1977-06-01
PT66509B (en) 1978-10-16

Similar Documents

Publication Publication Date Title
JPS54160353A (en) Novel phenoxyalkylcarboxylic derivative or its salt and sedative or antiiinflammatory agent containing them as active ingredient
NZ195568A (en) Guanidine derivatives and pharmaceutical compositions
PH14127A (en) 2-tetrahydrofurfuryl-5-lower alkyl-2'oxy-6,7-benzomorphans,salts thereof and compositions containing them
JPS5312860A (en) Novel halogenated 11azolyllbutane derivative and its salt* its preparation and fugicidal composition containing same as active ingredient
IL51403A0 (en) 1,2-dithiole derivatives processes for the preparation thereof and pharmaceutical compositions containing the same
DE3068803D1 (en) The use of 2-phenyltetralin derivatives, or heterocyclic analogues, in medicine and pharmaceutical compositions containing them
NZ183134A (en) I-i-(3-aryloxy-2-hydroxypropyl)-4-piperidyl-3-aryl-imid-azolidin or hexahydropyrimidin-2-ones; and pharmaceutical compositions
IL55728A0 (en) Novel 2-arylamino-hexahydtropyrimidines and imidazolidines,their salts and complexes thereof,their preparation and fungicidal compositions containing them
JPS5344568A (en) Alphaa*44biphenyl**benzyllazolium salt* its preparation and fungicidal composition containing same as major component
IL51402A0 (en) 1,2-dithiole derivatives processes for the preparation thereof and pharmaceutical compositions containing the same
IL52011A (en) Immunosuppressant pharmaceutical compositions containing 5-aminoalkyl isothiourea or 2-aminoalkyl imidazoline salts and some such novel compounds in the base or salt form
JPS5321161A (en) Novel nnsulphenylated oximecarbamate and its salt* thetr preparation and arthropocidal or nematocidal composition containing same as active ingredient
PH15697A (en) 2-acetoxymethyl-2-methyl-(5r)-penam-3a-carboxylic acid,base salts thereof and pharmaceutical compositions containing same
IL52587A0 (en) New pharmaceutical compositions containing aryl-(or aryloxy-) alkanolamines
PH13392A (en) Thiourea derivatives and pharmaceutical compositions containing them
IL52820A0 (en) New acylated heterocyclylcarboxylic acids and salts thereof their preparation and pharmaceutical compositions containing them
JPS5344566A (en) Novle tertialybutyllsubstituted pyrazolylcarbamate*its preparation and insecicidal or nematocidal composition containing same as active ingredient
NZ184808A (en) Heterocyclic compounds and pharmaceutical compositions
JPS52156934A (en) Pharmaceutical composition containing piperadine derivative and salt thereof
NZ189162A (en) Quaternary ammonium salts or phenylpropylamines and phenylbutylamines and pharmaceutical compositions
JPS52118492A (en) Novel amidinopenicillanoyl oxyalkylamoxylinate salts thereof process for preparing same and pharmaceutical composition containing same
JPS532466A (en) Novel 11acyloxyy11phenyll22azolyllethane or its salt* their preparation and fungicidal or nematocidal composition containing same as active ingredient
IL52134A0 (en) Uracil derivatives process for the preparation thereof and pharmaceutical compositions containing them
MY8600498A (en) Compositions containing chlorhexidine or salts thereof
NZ184084A (en) 2-carboxyalkyl-pyrrolid-in or piperidin-one or-dione derivatives and pharmaceutical compositions

Legal Events

Date Code Title Description
ERR Corrigendum

Free format text: THE CORRECT VERSION OF THE ABSTRACT A FREE-FLOWING, STABLE LIQUID FLAME RETARDANT MIXT INFORMATION