BE854553A - Derives de l'isothiouree - Google Patents

Derives de l'isothiouree

Info

Publication number
BE854553A
BE854553A BE177510A BE177510A BE854553A BE 854553 A BE854553 A BE 854553A BE 177510 A BE177510 A BE 177510A BE 177510 A BE177510 A BE 177510A BE 854553 A BE854553 A BE 854553A
Authority
BE
Belgium
Prior art keywords
isothiourea derivatives
isothiourea
derivatives
Prior art date
Application number
BE177510A
Other languages
English (en)
Original Assignee
Smith Kline French Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith Kline French Lab filed Critical Smith Kline French Lab
Publication of BE854553A publication Critical patent/BE854553A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/30—Isothioureas
    • C07C335/32—Isothioureas having sulfur atoms of isothiourea groups bound to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30—Oxygen or sulfur atoms
    • C07D233/42—Sulfur atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Transplantation (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
BE177510A 1976-05-14 1977-05-12 Derives de l'isothiouree BE854553A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB19994/76A GB1592453A (en) 1976-05-14 1976-05-14 Aminoalkyl esters of carbarimidothioic acid and compositions having immunosuppressant activity

Publications (1)

Publication Number Publication Date
BE854553A true BE854553A (fr) 1977-11-14

Family

ID=10138568

Family Applications (1)

Application Number Title Priority Date Filing Date
BE177510A BE854553A (fr) 1976-05-14 1977-05-12 Derives de l'isothiouree

Country Status (23)

Country Link
US (1) US4294854A (fr)
JP (1) JPS532420A (fr)
AR (1) AR218872A1 (fr)
AT (1) AT359521B (fr)
AU (1) AU509573B2 (fr)
BE (1) BE854553A (fr)
CA (1) CA1086758A (fr)
CH (1) CH620203A5 (fr)
DE (1) DE2721830A1 (fr)
DK (1) DK211277A (fr)
ES (1) ES458756A1 (fr)
FI (1) FI771400A (fr)
FR (2) FR2351098A1 (fr)
GB (1) GB1592453A (fr)
HU (1) HU174978B (fr)
IE (1) IE45144B1 (fr)
IL (1) IL52011A (fr)
LU (1) LU77332A1 (fr)
NL (1) NL7705331A (fr)
NO (1) NO771697L (fr)
PT (1) PT66509B (fr)
SE (1) SE7705658L (fr)
ZA (1) ZA772612B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0672244B2 (ja) * 1984-12-12 1994-09-14 三菱マテリアル株式会社 貴金属造粒装置
JPH08511266A (ja) * 1993-06-07 1996-11-26 アメリカ合衆国 Ｍｈｃクラス▲ｉ▼抑制剤の自己免疫疾患及び移植拒絶治療への使用
AU3230895A (en) * 1994-08-18 1996-03-14 Chugai Seiyaku Kabushiki Kaisha Amino acid derivative having nitrogen monoxide synthetase inhibitor activity
US7645873B2 (en) * 2003-03-20 2010-01-12 The Scripps Research Institute 6″-amino-6″-deoxygalactosylceramides
EP2058011A1 (fr) * 2007-11-07 2009-05-13 Wittycell Cellule Nkt activant des antigènes et/ou médicaments à liaison gycolipids covalentyl
RU2571267C2 (ru) * 2008-10-08 2015-12-20 Абивакс Вакцинная композиция против гриппа

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2648710A (en) * 1950-09-22 1953-08-11 Hoffmann La Roche Bis-quaternary salts of 1:10-bis-(dialkylamino)-5:6-dithia-decane
US2813102A (en) * 1956-04-10 1957-11-12 American Home Prod 2-(di-lower alkylaminoethylmercapto)-imidazolines and their acid addition salts and preparation thereof
US4152453A (en) * 1975-12-01 1979-05-01 Smith Kline & French Laboratories Limited Pharmacologically active compounds and compositions and methods of use

Also Published As

Publication number Publication date
ZA772612B (en) 1978-04-26
CH620203A5 (fr) 1980-11-14
IE45144L (en) 1977-11-14
AT359521B (de) 1980-11-10
CA1086758A (fr) 1980-09-30
JPS532420A (en) 1978-01-11
ATA318277A (de) 1980-04-15
IL52011A (en) 1982-05-31
LU77332A1 (fr) 1977-08-29
US4294854A (en) 1981-10-13
AR218872A1 (es) 1980-07-15
SE7705658L (sv) 1977-11-15
FR2351098B1 (fr) 1982-06-18
FR2351098A1 (fr) 1977-12-09
PT66509B (en) 1978-10-16
AU509573B2 (en) 1980-05-15
AU2507977A (en) 1978-11-16
FI771400A (fr) 1977-11-15
FR2472935A1 (fr) 1981-07-10
DE2721830A1 (de) 1977-11-24
DK211277A (da) 1977-11-15
NO771697L (no) 1977-11-15
IE45144B1 (en) 1982-06-30
ES458756A1 (es) 1978-03-01
NL7705331A (nl) 1977-11-16
PT66509A (en) 1977-06-01
HU174978B (hu) 1980-04-28
GB1592453A (en) 1981-07-08

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: SMITH KLINE & FRENCH LABORATORIES LTD

Effective date: 19850512