IL51085A - 2,9 -dichloro-6 -fluoro-16 -methyl-11 ,17,21-trihydroxy-pregna-1,4-diene-3,20-dione compounds, process for the manufacture thereof and pharmalceutical compositions containing them - Google Patents

2,9 -dichloro-6 -fluoro-16 -methyl-11 ,17,21-trihydroxy-pregna-1,4-diene-3,20-dione compounds, process for the manufacture thereof and pharmalceutical compositions containing them

Info

Publication number
IL51085A
IL51085A IL51085A IL5108576A IL51085A IL 51085 A IL51085 A IL 51085A IL 51085 A IL51085 A IL 51085A IL 5108576 A IL5108576 A IL 5108576A IL 51085 A IL51085 A IL 51085A
Authority
IL
Israel
Prior art keywords
pharmalceutical
pregna
trihydroxy
dichloro
diene
Prior art date
Application number
IL51085A
Other languages
English (en)
Other versions
IL51085A0 (en
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of IL51085A0 publication Critical patent/IL51085A0/xx
Publication of IL51085A publication Critical patent/IL51085A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J21/00Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0069Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • C07J5/0076Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
IL51085A 1975-12-12 1976-12-10 2,9 -dichloro-6 -fluoro-16 -methyl-11 ,17,21-trihydroxy-pregna-1,4-diene-3,20-dione compounds, process for the manufacture thereof and pharmalceutical compositions containing them IL51085A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1615075A CH626632A5 (en) 1975-12-12 1975-12-12 Process for the preparation of halopregnadienes

Publications (2)

Publication Number Publication Date
IL51085A0 IL51085A0 (en) 1977-02-28
IL51085A true IL51085A (en) 1980-09-16

Family

ID=4414834

Family Applications (1)

Application Number Title Priority Date Filing Date
IL51085A IL51085A (en) 1975-12-12 1976-12-10 2,9 -dichloro-6 -fluoro-16 -methyl-11 ,17,21-trihydroxy-pregna-1,4-diene-3,20-dione compounds, process for the manufacture thereof and pharmalceutical compositions containing them

Country Status (19)

Country Link
JP (1) JPS5273852A (xx)
AT (1) AT353432B (xx)
AU (1) AU510864B2 (xx)
BE (1) BE849267A (xx)
CA (1) CA1078824A (xx)
CH (2) CH626632A5 (xx)
DD (1) DD128682A5 (xx)
DE (1) DE2655802A1 (xx)
DK (1) DK142326B (xx)
ES (2) ES454119A1 (xx)
FR (1) FR2358152A1 (xx)
GB (1) GB1563595A (xx)
HU (1) HU176936B (xx)
IE (1) IE44512B1 (xx)
IL (1) IL51085A (xx)
NL (1) NL7613711A (xx)
NZ (1) NZ182865A (xx)
SE (1) SE7613919L (xx)
ZA (1) ZA767381B (xx)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT78973A (en) * 1984-07-25 1984-08-01 Joao Emerico Villax New preparation process of the 9alpha-fluoro 17,21-acylates or hidroxilades in 17 and 21 chloro-corticosteroid

Also Published As

Publication number Publication date
AT353432B (de) 1979-11-12
SE7613919L (sv) 1977-06-13
ZA767381B (en) 1977-11-30
JPS5273852A (en) 1977-06-21
DK142326B (da) 1980-10-13
CH626632A5 (en) 1981-11-30
ES454119A1 (es) 1978-03-01
BE849267A (fr) 1977-06-10
CA1078824A (en) 1980-06-03
GB1563595A (en) 1980-03-26
DK557576A (xx) 1977-06-13
FR2358152A1 (fr) 1978-02-10
HU176936B (hu) 1981-06-28
ATA914176A (de) 1979-04-15
IL51085A0 (en) 1977-02-28
ES465551A1 (es) 1978-09-16
DK142326C (xx) 1981-03-09
FR2358152B1 (xx) 1982-10-22
AU510864B2 (en) 1980-07-17
AU2047176A (en) 1978-06-15
DE2655802A1 (de) 1977-06-16
NZ182865A (en) 1979-06-08
NL7613711A (nl) 1977-06-14
IE44512B1 (en) 1981-12-30
CH626094A5 (en) 1981-10-30
DD128682A5 (de) 1977-12-07
IE44512L (en) 1977-06-12

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