IL42379A - Cartridge for an injection syringe - Google Patents

Cartridge for an injection syringe

Info

Publication number
IL42379A
IL42379A IL42379A IL4237973A IL42379A IL 42379 A IL42379 A IL 42379A IL 42379 A IL42379 A IL 42379A IL 4237973 A IL4237973 A IL 4237973A IL 42379 A IL42379 A IL 42379A
Authority
IL
Israel
Prior art keywords
shield
ampoule
cap
cartridge
protruding portion
Prior art date
Application number
IL42379A
Other versions
IL42379A0 (en
Original Assignee
Philips Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Philips Nv filed Critical Philips Nv
Publication of IL42379A0 publication Critical patent/IL42379A0/en
Publication of IL42379A publication Critical patent/IL42379A/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B67—OPENING, CLOSING OR CLEANING BOTTLES, JARS OR SIMILAR CONTAINERS; LIQUID HANDLING
    • B67B—APPLYING CLOSURE MEMBERS TO BOTTLES JARS, OR SIMILAR CONTAINERS; OPENING CLOSED CONTAINERS
    • B67B7/00—Hand- or power-operated devices for opening closed containers
    • B67B7/92—Hand- or power-operated devices for opening closed containers by breaking, e.g. for ampoules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
    • A61M5/285—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle with sealing means to be broken or opened
    • A61M5/286—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle with sealing means to be broken or opened upon internal pressure increase, e.g. pierced or burst
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M2005/3103—Leak prevention means for distal end of syringes, i.e. syringe end for mounting a needle
    • A61M2005/3104—Caps for syringes without needle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M2005/3103—Leak prevention means for distal end of syringes, i.e. syringe end for mounting a needle
    • A61M2005/3106—Plugs for syringes without needle

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Mechanical Engineering (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

Description

Cartridge for an injection syringe N.V. Philips* Gloeilampenfabrieken C: 40468 PHN. 6321.
VMI / WJM.
"Cartridge for an injection syringe".
The invention relates to a cartridge for an injection syringe, comprising an ampoule filled with a medium, a piston which can be displaced inside the ampoule, a thin-wall flexible diaphragm which closes the ampoule at one end, as well as a hollow shield which engages with the closed end of the ampoule and at the side facing away from the ampoule comprises a protruding portion which is provided with a central bore.
Such a cartridge is known from Netherlands Paten Application No. 67165^8. In this known cartridge a cannula is firmly clamped in the central bore of the protruding portion of the shield. The cannula is not exchangeable. This has the drawback that when different types of cannula are required, it is necessary to store a large stock of cartridges which are pro vided with the desired types of cannula.
We have developed a cartridge of the sort referred to in the preamble, which is not provided with a fixed cannula but on which different types of cannula can be fitted, as desired.
The cartridge according to the invention is characterized in that it comprises a cap provided with an inter nal spur is detachably connected with the protruding portion of the shield, the spur extending through the central bore of the protruding portion into the hollow shield.
After the cap has been removed from the cartridg a cannula of the desired diameter and length can be attached PHN. 6321 to the protruding portion of the shield. It is obvious that such a cannula should be provided with a coupling member which fits over the protruding portion of the shield.
In a suitable embodiment of the cartridge according to the invention the cap is attached to the protruding portion of the shield by means of a Luer coupling. After the cap has been removed any desired type of cannula provided with a Luer coupling member can be slid onto the protruding portion of the shield. Cannulas with a Luer coupling member are comraer cially available. For completeness, it is pointed out that a Luer coupling is formed by two mating conical faces whose coni calness has a standard value (angle between the generatrix of the conical surface and the axis is approximately 3°)· In a further suitable embodiment of the cartrid ge according to the invention it comprises one or more strips attached at one end to the outside of the cap and at the other end to the outside of the shield. The strips seal the cap and shield and have such a small thickness and are made of such a material that when the cap is twisted the strips are readily broken or become detached, so that the sealing is broken. The material from which the strips are made is preferably a synthe' tic material such as a polycarbonate, permitting the ends of the strips to be sealed to the cap and shield respectively by simply heating them, for example, by means of heating wires. The strips provide a means of checking the sterility of the cartridge according to the invention. From the fact whether or not the strips are intact the user of the cartridge can PHN. 6321. deduce whether the cartridge is still sterile. When the strips are broken, the cap has apparently been removed before and sterility is no longer guaranteed.
Preferably strips are used of a colour which co trasts with that of the cap and the shield. Similar to the strips , the cap and shield are preferably made of a synthetic material. For a reason to be mentioned hereinafter: the shield and preferably also the cap are made of a transparent synthetic material .
The invention will be described, by way of example, with reference to the following drawings, in which: Fig. 1 is a sectional view of the cartridge according to the invention, and Fig. 2 is a cross-sectional view of a separate cannula which can be used in conjunction with the cartridge according to the invention, In Fig. 1 the reference numeral 1 refers to a substantially cylindrical ampoule made of a rigid and transparent material. At one end the ampoule has a neck 2 and a flange 3. At the other end the ampoule contains a piston k which can be displaced inside the ampoule. The piston k is provided with a connection facility 5 for a piston rod. The neck 2 of the ampoule is closed by a stopper 6. The ampoule may contain a liquid medicament 7 » b t may alternatively be empty or contain a few drops of anti-coagulin, for example heparin or decumarol. The stopper 6 comprises a collar 8 and a cylindrical neck · The bottom of the collar 8 abuts the flat top surface of the PHN. 6321. flange 3> whilst the neck 9 accurately fits the inside of the neck 2. The cylindrical neck 9 is closed at the top by a thin diaphragm 10 which is integral with the stopper k and which ca readily be stretched spherically when pressure is exerted on the bottom.
The ampoule 1 is furthermore provided at the side of the neck 2 with a hollow shield 11 whose bottom edge 12 is clamped around the collar 8 of the stopper 6 and around flange 3 of the ampoule 1. In this way the collar 8 is firmly pressed home onto the flange 3 by means of the lower edge 12 of the shield 11 and the shield 11 is also firmly secured to the ampoule 1.
The shield 11 may also be attached to the ampou 1 in a different manner. For example, a separate clamping ring can be fitted over the flange portion 13 of shield 11, over collar 8 and over flange 3· In that case the shield 11 is not provided with a lower edge 12.
On the side facing away from the ampoule 1 the shield is provided with a protruding portion 14 having a centr bore 15· The portion Κ has a conical outer surface with a standard taper. The angle between a generatrix of the conical outer surface and the axis is approximately 3°· The protruding portion 14 of the shield 11 is provided with a cap 16 which is at least partly hollow and whose inner surface is conical.
The inner surface of cap l6 engages precisely with the conical outer surface of portion 1 . The cap 16 is PHN . 632 1 . provided with an internal central spur 1 shaped as a pin whic is provided with a point or with cutting edges and extends through the central bore 1 5 of the protruding portion 1 into the inside of the hollow shield 1 1 .
The outer surface of the cap 1 6 is furthermore provided with strips 1 8 . The ends of the strips 1 8 which face away from the cap, are connected to the outer surface of shiel 1 1 . The strips 18 may be integral with the cap 1 6 but may alte natively consist of separate strips attached at one end to the cap 1 6 , The strips are preferably made of a synthetic material, so that the attachment to the shield 1 1 , and in the case of separate strips also the, attachment to the cap 1 6 , can be effected in a simple manner, namely by means of a heating process. For completeness, it is to be rioted that the strips 1 8 have such a small thickness that when the cap 1 6 is twisted the strips 18 are broken or become detached. In order to obtai a suitable basis of attachment for the strips 1 8 and also to facilitate twisting of the cap 10, said cap is provided with a rim 1 · As previously stated, Fig. 2 is a cross-section view of a separate cannula which can be used in conjunction wi the catridge according to the invention.
The reference numeral 20 in Fig. 2 refers to a hollow cannula whose end which faces away from the point 21 is fixed in a holder 22 , which has a conical inner surface 23 · The conicalness of the inner surface 23 corresponds to that of the outer surface of the protruding portion 1 (Fig. 1 ) .
PHN. 632 1 .
Further, the internal dimensions of the holder 22 are the same or slightly greater than, the external dimensions of the protr ing portion I k (Fig. 1 ) , so that the holder 22 fits portion 1 .
The operation of the device according to the invention as shown in Fig. 1 is as follows.
The piston k is pushed upwards with the aid of piston rod connected to part 5 » thus compressing the medium, such as a liquid medicament 7 » contained in the ampoule 1 . As result, pressure will be exerted on the underside of the diaph 1 0 and owing to the elasticity of said diaphragm, it is stretc spherically within the space available for this in the hollow shield 1 1 . When the diaphragm wall is stretched or domed, it becomes increasingly thinner until it is ruptured or until the diaphragm comes into contact with the point or cutting edge of the spur 1 and is thus ruptured. As a result of the elasticit of the diaphragm, it will contract upon being broken or rupture so that an open communication is obtained between the interior of the shield 1 1 and the ampoule 1. When the shield 1 1 is made of a transparent material, the presence of medicament inside t shield 1 1 can be observed, from which the conclusion may be dr that the diaphragm is ruptured and a communication is obtained between the interior of the ampoule 1 and the shield 1 1 .
The pressure on the piston k is now removed and due to the counter-pressure exerted by the compressed air in t shield 1 1 , the piston will slightly spring back.
Subsequently a rotation force is exerted on the cap 1 6. in order to break the strips 1 8 by which the cap 1 6 is PHN. 632 1 . sealed to the shield 1 1 . After the strips are broken, the cap 1 6 is removed and the plug-on cannula is slid onto the externa surface of the protruding portion ~\h with the internal surface 23 of the holder 22 . The cartridge according to the invention now ready for an injection; the cannula 20 is then inserted in the patient ' s body and the medicament 7 can be administered vi the cannula 20 by displacing the piston .
The cartridge according to the invention may al be used for taking a fluid sample from a patient . The ampoule 1 is then provided with a sterile gaseous medium such as steri air and may furthermore contain a few drops of an anti-coaguli In a similar way as described hereinbefore . or a liquid medium the gaseous medium is pressurized by displacing the piston . As a result, the diaphragm 1 0 bulges up in the interior of the shield 1 1 . Upon rupturing of the diaphragm due to bulging, the pressure of the piston is discontinued and subsequently the cap 1 6 is removed. As a result, the strips 1 8 are broken. Subsequently the cartridge according to the invention is provided in the manner indicated hereinbefore with a plug-on cannula as for example, the cannula 20-23 shown in Fig. 2 . The piston k is now pushed upwards as far as is desirable so that the gaseo medium is at least partially forced out. The anti-coagulant will then moisten the inner wall of the ampoule 1 and possibly of the shield 1 1 , but owing to its small voltime it is not forced out via the cannula 20 . The cannula 20 is subsequently inserted in the patient's body and by withdrawing the piston , d m t e ati nt 1 s b d can be cau ht in the am oule 1 PHN. 6321. via the cannula 20. The transparent shield 11 as well as the transparent ampoule 7 make it possible to observe whether the injection is performed in the correct manner and whether the desired fluid is obtained. 42379/3 - i

Claims (3)

1. A cartridge for an injection syringe, comprising a glass ampoule filled with a medium, a piston which can be displaced in3ide the ampoule, a thin-wall flexible diaphragm which closes the ampoule at one end, and a hollow shield which engages with the closed end of the ampoule and which at the side facing away from the ampoule comprises a protruding portion which is provided with a central bore, characterized in that the cartridge comprises a cap provided with an internal spur which is detachably connected with the protruding portion of the shield, the spur extending through the central bore of the protruding portion into the hollow shield and being provided with cutting means capable of rupturing the diaphragm when bulged.
2. A cartridge as claimed in Claim 1, characterized in that the cap is attached to the protruding portion of the shield by means of a Luer coupling.
3. A cartridge as claimed in Claim 1 or 2, characterized in tha the cartridge comprises one or more strips which are attached at one end to the outside of the cap and at the other end to the outside of the shield. For the Applicants PARTNERS HE:cb
IL42379A 1972-06-01 1973-05-29 Cartridge for an injection syringe IL42379A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL7207394.A NL165381C (en) 1972-06-01 1972-06-01 CARTRIDGE FOR AN INJECTION SYRINGE.

Publications (2)

Publication Number Publication Date
IL42379A0 IL42379A0 (en) 1973-07-30
IL42379A true IL42379A (en) 1977-02-28

Family

ID=19816183

Family Applications (1)

Application Number Title Priority Date Filing Date
IL42379A IL42379A (en) 1972-06-01 1973-05-29 Cartridge for an injection syringe

Country Status (14)

Country Link
JP (2) JPS4943482A (en)
AT (1) AT343269B (en)
BE (1) BE800394A (en)
CA (1) CA1001033A (en)
CH (1) CH557684A (en)
DE (1) DE2324838C3 (en)
ES (1) ES217488Y (en)
FR (1) FR2186270B1 (en)
GB (1) GB1386030A (en)
IL (1) IL42379A (en)
IN (1) IN138956B (en)
IT (1) IT988733B (en)
NL (1) NL165381C (en)
SE (1) SE399824B (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3989045A (en) * 1972-09-29 1976-11-02 Eck William F Van Hypodermic syringe
DE7919910U1 (en) * 1979-07-11 1979-12-13 Von Heyden Gmbh, 8000 Muenchen INJECTION SYRINGE
US4465472A (en) * 1982-11-22 1984-08-14 American Hospital Supply Corp. Syringe cartridge and method
JPS6071226U (en) * 1983-10-24 1985-05-20 昭和電工株式会社 Ampoule syringe
ATE42684T1 (en) * 1984-11-21 1989-05-15 Ewald Pickhard INJECTION SYRINGE.
DE3531071A1 (en) * 1985-08-30 1987-03-05 Merck Patent Gmbh OPENING AID FOR AMPOULES
AU595096B2 (en) * 1988-02-10 1990-03-22 Astra Pharmaceuticals Pty Ltd Plastic cartridge and syringe
EP0737485A4 (en) * 1993-12-28 1998-02-04 Tetsuro Higashikawa Syringe
AUPM922394A0 (en) * 1994-11-03 1994-11-24 Astra Pharmaceuticals Pty Ltd Plastic syringe with overcap
AU4219297A (en) * 1996-09-10 1998-04-02 Tetsuro Higashikawa Slide valve for syringes, syringe, and kit preparations
DE19638940C2 (en) * 1996-09-23 1999-01-07 Vetter & Co Apotheker Prefilled syringe for medical purposes

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE7039555U (en) * 1971-01-21 Bavnsfelt H Device for dispensing drugs or the like from containers
FR1063558A (en) * 1952-09-23 1954-05-04 Elbow valve with cylindrical bezel
GB725024A (en) * 1952-11-07 1955-03-02 Lilly Co Eli Improvements in or relating to closure member for a syringe
DE947423C (en) * 1953-11-24 1956-08-16 Hoechst Ag Cannula cap for bottles with injection solutions
DE1853121U (en) * 1962-03-23 1962-06-07 Arzneimittelwerk Fischer O H G Bottle cap
CH458632A (en) * 1967-10-18 1968-06-30 Jay Sarnoff Stanley Injection syringe
FR2058552A6 (en) * 1969-09-15 1971-05-28 Ethnor

Also Published As

Publication number Publication date
FR2186270A1 (en) 1974-01-11
JPS5541224Y2 (en) 1980-09-26
ES217488Y (en) 1977-01-01
FR2186270B1 (en) 1976-11-12
NL7207394A (en) 1973-12-04
BE800394A (en) 1973-12-03
ES217488U (en) 1976-08-16
NL165381B (en) 1980-11-17
DE2324838B2 (en) 1980-06-12
ATA468773A (en) 1977-09-15
JPS5589444U (en) 1980-06-20
AT343269B (en) 1978-05-26
DE2324838A1 (en) 1973-12-20
CA1001033A (en) 1976-12-07
NL165381C (en) 1981-04-15
IL42379A0 (en) 1973-07-30
IN138956B (en) 1976-04-17
IT988733B (en) 1975-04-30
SE399824B (en) 1978-03-06
GB1386030A (en) 1975-03-05
JPS4943482A (en) 1974-04-24
AU5617273A (en) 1974-11-28
DE2324838C3 (en) 1981-04-23
CH557684A (en) 1975-01-15

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