IL172840A0 - Benzimidazole derivatives and their use as protein kinases inhibitors - Google Patents

Benzimidazole derivatives and their use as protein kinases inhibitors

Info

Publication number
IL172840A0
IL172840A0 IL172840A IL17284005A IL172840A0 IL 172840 A0 IL172840 A0 IL 172840A0 IL 172840 A IL172840 A IL 172840A IL 17284005 A IL17284005 A IL 17284005A IL 172840 A0 IL172840 A0 IL 172840A0
Authority
IL
Israel
Prior art keywords
protein kinases
benzimidazole derivatives
kinases inhibitors
inhibitors
benzimidazole
Prior art date
Application number
IL172840A
Other versions
IL172840A (en
Original Assignee
Astex Therapeutics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB0315657.7A external-priority patent/GB0315657D0/en
Priority claimed from GB0324919A external-priority patent/GB0324919D0/en
Priority claimed from PCT/GB2004/002824 external-priority patent/WO2005002552A2/en
Application filed by Astex Therapeutics Ltd filed Critical Astex Therapeutics Ltd
Publication of IL172840A0 publication Critical patent/IL172840A0/en
Publication of IL172840A publication Critical patent/IL172840A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
IL172840A 2003-07-03 2005-12-27 Benzimidazole derivatives and their use as protein kinase inhibitors IL172840A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US48468503P 2003-07-03 2003-07-03
GBGB0315657.7A GB0315657D0 (en) 2003-07-03 2003-07-03 Pharmaceutical compounds
US51437403P 2003-10-24 2003-10-24
GB0324919A GB0324919D0 (en) 2003-10-24 2003-10-24 Pharmaceutical compounds
PCT/GB2004/002824 WO2005002552A2 (en) 2003-07-03 2004-07-05 Benzimidazole derivatives and their use as protein kinases inhibitors

Publications (2)

Publication Number Publication Date
IL172840A0 true IL172840A0 (en) 2006-06-11
IL172840A IL172840A (en) 2014-07-31

Family

ID=33568694

Family Applications (1)

Application Number Title Priority Date Filing Date
IL172840A IL172840A (en) 2003-07-03 2005-12-27 Benzimidazole derivatives and their use as protein kinase inhibitors

Country Status (4)

Country Link
KR (1) KR101190964B1 (en)
CY (2) CY1114846T1 (en)
HK (1) HK1087925A1 (en)
IL (1) IL172840A (en)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA04003954A (en) * 2001-10-26 2004-11-29 Aventis Pharma Inc Benzimidazoles and analogues and their use as protein kinases inhibitors.

Also Published As

Publication number Publication date
KR20060082847A (en) 2006-07-19
IL172840A (en) 2014-07-31
KR101190964B1 (en) 2012-10-12
HK1087925A1 (en) 2006-10-27
CY1115093T1 (en) 2016-12-14
CY1114846T1 (en) 2016-12-14

Similar Documents

Publication Publication Date Title
SI1648426T1 (en) Benzimidazole derivatives and their use as protein kinases inhibitors
IL176233A0 (en) Organophosphorous indazole derivatives and use thereof as protein kinase inhibitors
IL161576A0 (en) Benzimidazoles and analogues and their use as protein kinases inhibitors
ZA200500680B (en) Quinoline derivatives and their use as mycrobacterial inhibitors
IL173380A0 (en) Pyridinylamino-pyrimidine derivatives as protein kinase inhibitors
ZA200704888B (en) Pyrrolopyrazines and pyrazolopyrazines useful as inhibitors of protein kinases
PL376789A1 (en) Aminoindazole derivatives and use thereof as kinase inhibitors
IL173490A0 (en) 4-pyrimidone derivatives and their use as peptidyl peptidase inhibitors
PT1562589E (en) Diaminotriazoles useful as inhibitors of protein kinases
PL375447A1 (en) Protein kinase inhibitors and uses thereof
PL403456A1 (en) 5-phenylthiazole derivatives and their use as Pi3 kinase inhibitors
IL161516A0 (en) Benzimidazoles useful as protein kinase inhibitors
IL151045A0 (en) 2-benzothiazolyl urea derivatives and their use as protein kinase inhibitors
HK1099764A1 (en) Quinoxalines useful as inhibitors of protein kinases
PT1997811E (en) Indazole, benzoxazole and pyrazolopyridine derivatives as p38 kinase inhibitors
HK1112895A1 (en) 5-heteroaryl thiazoles and their use as pi3k inhibitors
HK1067945A1 (en) Substituted benzazoles and use thereof as raf kinase inhibitors
AU2003256297A1 (en) Benzimidazoles and benzothiazoles as inhibitors of map kinase
AU2003254053A8 (en) Pyrazolopyrimidines as protein kinase inhibitors
IL172257A0 (en) Substituted pyrrole derivatives and their use as hmg-co inhibitors
ZA200606070B (en) Substituted quinolines and their use as mycrobacterial inhibitors
EP1922086A4 (en) Targeted protein kinase c inhibitors and uses thereof
EP1877424A4 (en) Inhibitors of protein kinases and uses thereof
AU2003215756A8 (en) Benzimidazoles and their use as mitogen-activated- and rho-kinase inhibitors
PL374581A1 (en) Diaminothiazoles and use thereof as cdk4 inhibitors

Legal Events

Date Code Title Description
FF Patent granted
MM9K Patent not in force due to non-payment of renewal fees