IL155506A0 - Process for folding chemically synthesized polypeptides - Google Patents

Process for folding chemically synthesized polypeptides

Info

Publication number
IL155506A0
IL155506A0 IL15550601A IL15550601A IL155506A0 IL 155506 A0 IL155506 A0 IL 155506A0 IL 15550601 A IL15550601 A IL 15550601A IL 15550601 A IL15550601 A IL 15550601A IL 155506 A0 IL155506 A0 IL 155506A0
Authority
IL
Israel
Prior art keywords
chemically synthesized
folding
synthesized polypeptides
cysteine
reducing agent
Prior art date
Application number
IL15550601A
Other languages
English (en)
Original Assignee
Rmf Dictagene Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rmf Dictagene Sa filed Critical Rmf Dictagene Sa
Publication of IL155506A0 publication Critical patent/IL155506A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
    • C07K1/1133—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by redox-reactions involving cystein/cystin side chains
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IL15550601A 2000-11-27 2001-11-27 Process for folding chemically synthesized polypeptides IL155506A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00204207 2000-11-27
PCT/EP2001/014163 WO2002050099A2 (en) 2000-11-27 2001-11-27 Process for folding chemically synthesized polypeptides

Publications (1)

Publication Number Publication Date
IL155506A0 true IL155506A0 (en) 2003-11-23

Family

ID=8172340

Family Applications (1)

Application Number Title Priority Date Filing Date
IL15550601A IL155506A0 (en) 2000-11-27 2001-11-27 Process for folding chemically synthesized polypeptides

Country Status (22)

Country Link
US (2) US20020082384A1 (es)
EP (2) EP1679318A1 (es)
JP (1) JP2004516300A (es)
KR (1) KR20030081315A (es)
CN (2) CN1830999A (es)
AT (1) ATE322501T1 (es)
AU (2) AU2002229603B2 (es)
BR (1) BR0113091A (es)
CA (1) CA2416054A1 (es)
CU (1) CU23034A3 (es)
DE (1) DE60118598T2 (es)
DK (1) DK1337549T3 (es)
ES (1) ES2261509T4 (es)
HU (1) HUP0302395A3 (es)
IL (1) IL155506A0 (es)
MX (1) MXPA03003576A (es)
NO (1) NO20032356L (es)
NZ (1) NZ523679A (es)
PL (1) PL364932A1 (es)
RU (1) RU2275377C2 (es)
WO (1) WO2002050099A2 (es)
ZA (1) ZA200300642B (es)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7091310B2 (en) * 2002-09-13 2006-08-15 Chemokine Therapeutics Corporation Chemokine analogs for the treatment of human disease
US7214660B2 (en) 2001-10-10 2007-05-08 Neose Technologies, Inc. Erythropoietin: remodeling and glycoconjugation of erythropoietin
US7173003B2 (en) 2001-10-10 2007-02-06 Neose Technologies, Inc. Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF
EP2338333B1 (en) 2003-04-09 2017-09-06 ratiopharm GmbH Glycopegylation methods and proteins/peptides produced by the methods
US9005625B2 (en) 2003-07-25 2015-04-14 Novo Nordisk A/S Antibody toxin conjugates
US20080305992A1 (en) 2003-11-24 2008-12-11 Neose Technologies, Inc. Glycopegylated erythropoietin
AU2005298840B2 (en) * 2004-10-26 2010-09-16 Lonza Ag S-alkyl-sulphenyl protection groups in solid-phase synthesis
SI2586456T1 (sl) 2004-10-29 2016-05-31 Ratiopharm Gmbh Preoblikovanje in glikopegliacija fibroblastnega rastnega faktorja (FGF)
AU2006203792B2 (en) 2005-01-10 2011-11-03 Ratiopharm Gmbh Glycopegylated Granulocyte Colony Stimulating Factor
WO2006121569A2 (en) 2005-04-08 2006-11-16 Neose Technologies, Inc. Compositions and methods for the preparation of protease resistant human growth hormone glycosylation mutants
WO2006134173A2 (en) * 2005-06-17 2006-12-21 Novo Nordisk Health Care Ag Selective reduction and derivatization of engineered proteins comprising at least one non-native cysteine
US20070105755A1 (en) 2005-10-26 2007-05-10 Neose Technologies, Inc. One pot desialylation and glycopegylation of therapeutic peptides
WO2007056191A2 (en) 2005-11-03 2007-05-18 Neose Technologies, Inc. Nucleotide sugar purification using membranes
JP2009520739A (ja) * 2005-12-23 2009-05-28 アプラゲン ゲーエムベーハー ジスルフィド架橋の形成方法
JP2009535402A (ja) * 2006-05-03 2009-10-01 マリンクロッド・インコーポレイテッド 保護ペプチドを樹脂から放出するための組成物および方法
JP2009544327A (ja) 2006-07-21 2009-12-17 ノヴォ ノルディスク アー／エス Ｏ−結合型グリコシル化配列によるペプチドのグリコシル化
US20100075375A1 (en) 2006-10-03 2010-03-25 Novo Nordisk A/S Methods for the purification of polypeptide conjugates
EP2144923B1 (en) 2007-04-03 2013-02-13 BioGeneriX AG Methods of treatment using glycopegylated g-csf
US9493499B2 (en) 2007-06-12 2016-11-15 Novo Nordisk A/S Process for the production of purified cytidinemonophosphate-sialic acid-polyalkylene oxide (CMP-SA-PEG) as modified nucleotide sugars via anion exchange chromatography
US20100203001A1 (en) * 2007-07-11 2010-08-12 Aplagen Gmbh Process for forming disulfide bridges
WO2009108806A1 (en) 2008-02-27 2009-09-03 Novo Nordisk A/S Conjugated factor viii molecules
CN104844693B (zh) * 2015-06-10 2018-08-03 成都圣诺生物科技股份有限公司 一种合成利那洛肽的方法
WO2019149918A1 (en) 2018-02-02 2019-08-08 Novo Nordisk A/S Drug injection device with deflectable transducer
CN111100188A (zh) * 2018-10-25 2020-05-05 成都医学院 一种制备蜘蛛抗菌肽的方法
CN109593119A (zh) * 2019-01-27 2019-04-09 上海丽珠制药有限公司 一种[2-d-组氨酸]-醋酸亮丙瑞林的制备方法
JP7453745B2 (ja) * 2019-03-28 2024-03-21 株式会社ヤクルト本社 毒性タンパク質の活性を阻害するペプチドのスクリーニング方法及び毒性タンパク質の製造方法
CN110845595A (zh) * 2019-11-14 2020-02-28 连云港职业技术学院 一种固相合成5-tmara标记的铁调素-25的方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2923787A1 (de) * 1979-06-12 1980-12-18 Max Planck Gesellschaft Verfahren zur selektiven bildung von disulfidbruecken in polypeptiden und die dabei erhaltenen produkte als wirkstoffe enthaltende arzneimittel
DE3236849A1 (de) * 1982-10-05 1984-04-05 Max Planck Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen Neue thiohydrazin-1,2-dicarbonsaeure-derivate, verfahren zu ihrer herstellung und ihre verwendung
IL96682A0 (en) * 1989-12-15 1991-09-16 Amgen Inc Production of biologically active platelet-derived growth factor from high expression host cell systems
CA2072249C (en) * 1991-06-28 2003-06-17 Saiko Hosokawa Human monoclonal antibody specifically binding to surface antigen of cancer cell membrane
EP0628573A1 (en) * 1993-05-24 1994-12-14 Kao Corporation Process for producing solubilized protein
US5663304A (en) * 1993-08-20 1997-09-02 Genentech, Inc. Refolding of misfolded insulin-like growth factor-I
DE4431317A1 (de) * 1994-09-02 1996-03-07 Biotechnolog Forschung Gmbh Schutz- bzw. Ankergruppen und deren Verwendung

Also Published As

Publication number Publication date
AU2960302A (en) 2002-07-01
EP1337549A2 (en) 2003-08-27
CN1830999A (zh) 2006-09-13
RU2275377C2 (ru) 2006-04-27
NO20032356D0 (no) 2003-05-26
MXPA03003576A (es) 2003-10-14
WO2002050099A3 (en) 2002-09-19
DK1337549T3 (da) 2006-07-31
HUP0302395A2 (hu) 2003-10-28
KR20030081315A (ko) 2003-10-17
US20020082384A1 (en) 2002-06-27
DE60118598D1 (de) 2006-05-18
CU23034A3 (es) 2005-03-22
EP1679318A1 (en) 2006-07-12
PL364932A1 (en) 2004-12-27
EP1337549B1 (en) 2006-04-05
JP2004516300A (ja) 2004-06-03
WO2002050099A2 (en) 2002-06-27
DE60118598T2 (de) 2007-02-15
AU2002229603B2 (en) 2007-11-08
HUP0302395A3 (en) 2007-05-02
NO20032356L (no) 2003-05-26
ES2261509T3 (es) 2006-11-16
BR0113091A (pt) 2003-07-08
CN1449406A (zh) 2003-10-15
ATE322501T1 (de) 2006-04-15
ES2261509T4 (es) 2008-02-16
US20050239162A1 (en) 2005-10-27
CN1249078C (zh) 2006-04-05
NZ523679A (en) 2005-10-28
ZA200300642B (en) 2004-07-16
CA2416054A1 (en) 2002-06-27

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