IL137120A - Process for preparing (r)-2-bromo-3-phenyl-propionic acid - Google Patents

Process for preparing (r)-2-bromo-3-phenyl-propionic acid

Info

Publication number: IL137120A
Authority: IL; Israel
Prior art keywords: phenyl; bromo; preparing; propionic acid; alanine
Prior art date: 1998-02-18

Application number

IL13712099A

Other languages

English (en)

Other versions

IL137120A0 (en

Original Assignee

Zambon Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-02-18

Filing date

1999-01-26

Publication date

2005-06-19

1999-01-26 Application filed by Zambon Spa filed Critical Zambon Spa

2001-06-14 Publication of IL137120A0 publication Critical patent/IL137120A0/xx

2005-06-19 Publication of IL137120A publication Critical patent/IL137120A/xx

Links

WDRSCFNERFONKU-MRVPVSSYSA-N (2r)-2-bromo-3-phenylpropanoic acid Chemical compound OC(=O)[C@H](Br)CC1=CC=CC=C1 WDRSCFNERFONKU-MRVPVSSYSA-N 0.000 title abstract 2
238000004519 manufacturing process Methods 0.000 title abstract 2
LPXPTNMVRIOKMN-UHFFFAOYSA-M sodium nitrite Chemical compound [Na+].[O-]N=O LPXPTNMVRIOKMN-UHFFFAOYSA-M 0.000 abstract 2
BMYNFMYTOJXKLE-UHFFFAOYSA-N 3-azaniumyl-2-hydroxypropanoate Chemical compound NCC(O)C(O)=O BMYNFMYTOJXKLE-UHFFFAOYSA-N 0.000 abstract 1
COLNVLDHVKWLRT-MRVPVSSYSA-N D-phenylalanine Chemical compound OC(=O)[C@H](N)CC1=CC=CC=C1 COLNVLDHVKWLRT-MRVPVSSYSA-N 0.000 abstract 1
239000003125 aqueous solvent Substances 0.000 abstract 1
150000004945 aromatic hydrocarbons Chemical class 0.000 abstract 1
150000008282 halocarbons Chemical class 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
235000010288 sodium nitrite Nutrition 0.000 abstract 1
239000002904 solvent Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
- C07C51/363—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Oil, Petroleum & Natural Gas (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

IL13712099A 1998-02-18 1999-01-26 Process for preparing (r)-2-bromo-3-phenyl-propionic acid IL137120A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IT98MI000302A IT1298268B1 (it)	1998-02-18	1998-02-18	Procedimento per la preparazione dell'acido (s)-2-bromo-3-fenil- propionico
PCT/EP1999/000468 WO1999042431A1 (en)	1998-02-18	1999-01-26	Process for preparing (r)-2-bromo-3-phenyl-propionic acid

Publications (2)

Publication Number	Publication Date
IL137120A0 IL137120A0 (en)	2001-06-14
IL137120A true IL137120A (en)	2005-06-19

Family

ID=11378968

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL13712099A IL137120A (en)	1998-02-18	1999-01-26	Process for preparing (r)-2-bromo-3-phenyl-propionic acid

Country Status (10)

Country	Link
US (1)	US6103931A (xx)
EP (1)	EP1056707B1 (xx)
AT (1)	ATE285393T1 (xx)
CA (1)	CA2321001A1 (xx)
DE (1)	DE69922792D1 (xx)
HU (1)	HUP0100253A3 (xx)
IL (1)	IL137120A (xx)
IT (1)	IT1298268B1 (xx)
WO (1)	WO1999042431A1 (xx)
ZA (1)	ZA99812B (xx)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL1014353C2 (nl) *	2000-02-11	2001-08-15	Dsm Nv	Werkwijze voor de bereiding van (R) -2-broom-3-fenylpropaanzuur.
ES2227069T3 (es) *	2000-03-30	2005-04-01	Ajinomoto Co., Inc.	Metodo de produccion de un derivado de acido acetiltiocarboxilico aromatico.
US6620600B2 (en)	2000-09-15	2003-09-16	Bristol-Myers Squibb Co.	Enzymatic resolution of aryl and thio-substituted acids
EP1324975B1 (en)	2000-09-29	2005-11-16	Bristol-Myers Squibb Company	Dynamic resolution of isomers and resolved isomers
US20050245764A1 (en) *	2001-08-08	2005-11-03	Koki Yamashita	Process for producing optically active 2-substituted carboxylic acid
EP1481960A4 (en) *	2002-02-04	2005-04-06	Kaneka Corp	PROCESS FOR OBTAINING OPTICALLY ACTIVE 2-HALOGENO-CARBOXYLIC ACIDS

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4339600A (en) *	1976-05-10	1982-07-13	E. R. Squibb & Sons, Inc.	Compounds for alleviating angiotensin related hypertension
JPS56158732A (en) *	1980-05-14	1981-12-07	Toyo Soda Mfg Co Ltd	Preparation of alpha-halogeno-beta-phenylpropionic acid
FR2679564A1 (fr) *	1991-07-23	1993-01-29	Inst Nat Sante Rech Med	Nouveaux acylmercaptoalcanoldipeptides, leur preparation et les compositions qui les contiennent.
KR100281450B1 (ko) *	1992-05-15	2001-02-01	슈테펜 엘. 네스비트	엔케팔리나제 및 안지오텐신 전환 효소의 억제제로서 유용한 신규 메르캅토아세틸아미도 피리다조[1,2]피리다진, 피라졸로[1,2]피리다진, 피리다조[1,2-a][1,2]디아제핀 및 피라졸로[1,2-a][1,2]디아제핀 유도체
US5238932A (en) *	1992-05-20	1993-08-24	Merrell Dow Pharmaceuticals Inc.	Mercaptoacetylamide tricyclic derivatives useful as inhibitors of enkephalinase
US5504080A (en) *	1992-10-28	1996-04-02	Bristol-Myers Squibb Co.	Benzo-fused lactams
US5508272A (en) *	1993-06-15	1996-04-16	Bristol-Myers Squibb Company	Compounds containing a fused bicycle ring and processes therefor
US5525723A (en) *	1993-11-18	1996-06-11	Bristol-Myers Squibb Co.	Compounds containing a fused multiple ring lactam

1998
- 1998-02-18 IT IT98MI000302A patent/IT1298268B1/it active IP Right Grant
1999
- 1999-01-26 DE DE69922792T patent/DE69922792D1/de not_active Expired - Fee Related
- 1999-01-26 IL IL13712099A patent/IL137120A/xx active IP Right Grant
- 1999-01-26 WO PCT/EP1999/000468 patent/WO1999042431A1/en active IP Right Grant
- 1999-01-26 CA CA002321001A patent/CA2321001A1/en not_active Abandoned
- 1999-01-26 EP EP99903680A patent/EP1056707B1/en not_active Expired - Lifetime
- 1999-01-26 HU HU0100253A patent/HUP0100253A3/hu unknown
- 1999-01-26 AT AT99903680T patent/ATE285393T1/de not_active IP Right Cessation
- 1999-02-02 ZA ZA9900812A patent/ZA99812B/xx unknown
- 1999-02-17 US US09/251,432 patent/US6103931A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
EP1056707A1 (en)	2000-12-06
HUP0100253A3 (en)	2002-09-30
EP1056707B1 (en)	2004-12-22
US6103931A (en)	2000-08-15
ZA99812B (en)	1999-08-02
ITMI980302A1 (it)	1999-08-18
HUP0100253A2 (hu)	2001-05-28
CA2321001A1 (en)	1999-08-26
IL137120A0 (en)	2001-06-14
IT1298268B1 (it)	1999-12-20
ATE285393T1 (de)	2005-01-15
WO1999042431A1 (en)	1999-08-26
DE69922792D1 (de)	2005-01-27

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Legal Events

Date	Code	Title	Description
2006-01-15	FF	Patent granted
2006-01-15	KB	Patent renewed