DE69922792D1 - Verfahren zur herstellung von (r)-2-brom-3-phenylpropionsäure - Google Patents

Verfahren zur herstellung von (r)-2-brom-3-phenylpropionsäure

Info

Publication number: DE69922792D1
Authority: DE; Germany
Prior art keywords: brom; preparation; phenylpropionic acid; phenyl; alanine
Prior art date: 1998-02-18
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Fee Related

Application number

DE69922792T

Other languages

English (en)

Inventor

Pietro Allegrini

Giorgio Soriato

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Zambon SpA

Original Assignee

Zambon SpA

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-02-18

Filing date

1999-01-26

Publication date

2005-01-27

1999-01-26 Application filed by Zambon SpA filed Critical Zambon SpA

2005-01-27 Application granted granted Critical

2005-01-27 Publication of DE69922792D1 publication Critical patent/DE69922792D1/de

2019-01-27 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Links

WDRSCFNERFONKU-MRVPVSSYSA-N (2r)-2-bromo-3-phenylpropanoic acid Chemical compound OC(=O)[C@H](Br)CC1=CC=CC=C1 WDRSCFNERFONKU-MRVPVSSYSA-N 0.000 title abstract 2
LPXPTNMVRIOKMN-UHFFFAOYSA-M sodium nitrite Chemical compound [Na+].[O-]N=O LPXPTNMVRIOKMN-UHFFFAOYSA-M 0.000 abstract 2
BMYNFMYTOJXKLE-UHFFFAOYSA-N 3-azaniumyl-2-hydroxypropanoate Chemical compound NCC(O)C(O)=O BMYNFMYTOJXKLE-UHFFFAOYSA-N 0.000 abstract 1
COLNVLDHVKWLRT-MRVPVSSYSA-N D-phenylalanine Chemical compound OC(=O)[C@H](N)CC1=CC=CC=C1 COLNVLDHVKWLRT-MRVPVSSYSA-N 0.000 abstract 1
239000003125 aqueous solvent Substances 0.000 abstract 1
150000004945 aromatic hydrocarbons Chemical class 0.000 abstract 1
150000008282 halocarbons Chemical class 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
235000010288 sodium nitrite Nutrition 0.000 abstract 1
239000002904 solvent Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
- C07C51/363—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Oil, Petroleum & Natural Gas (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

DE69922792T 1998-02-18 1999-01-26 Verfahren zur herstellung von (r)-2-brom-3-phenylpropionsäure Expired - Fee Related DE69922792D1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IT98MI000302A IT1298268B1 (it)	1998-02-18	1998-02-18	Procedimento per la preparazione dell'acido (s)-2-bromo-3-fenil- propionico
PCT/EP1999/000468 WO1999042431A1 (en)	1998-02-18	1999-01-26	Process for preparing (r)-2-bromo-3-phenyl-propionic acid

Publications (1)

Publication Number	Publication Date
DE69922792D1 true DE69922792D1 (de)	2005-01-27

Family

ID=11378968

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE69922792T Expired - Fee Related DE69922792D1 (de)	1998-02-18	1999-01-26	Verfahren zur herstellung von (r)-2-brom-3-phenylpropionsäure

Country Status (10)

Country	Link
US (1)	US6103931A (de)
EP (1)	EP1056707B1 (de)
AT (1)	ATE285393T1 (de)
CA (1)	CA2321001A1 (de)
DE (1)	DE69922792D1 (de)
HU (1)	HUP0100253A3 (de)
IL (1)	IL137120A (de)
IT (1)	IT1298268B1 (de)
WO (1)	WO1999042431A1 (de)
ZA (1)	ZA99812B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL1014353C2 (nl) *	2000-02-11	2001-08-15	Dsm Nv	Werkwijze voor de bereiding van (R) -2-broom-3-fenylpropaanzuur.
EP1138671B1 (de) *	2000-03-30	2004-09-01	Ajinomoto Co., Inc.	Verfahren zur Herstellung von aromatischen Acylthiocarbonsäurederivaten
US6620600B2 (en) *	2000-09-15	2003-09-16	Bristol-Myers Squibb Co.	Enzymatic resolution of aryl and thio-substituted acids
EP1324975B1 (de)	2000-09-29	2005-11-16	Bristol-Myers Squibb Company	Dynamische trennung von isomeren und getrennte isomere
EP1422215A4 (de) *	2001-08-08	2005-07-06	Kaneka Corp	Verfahren zur herstellung einer optisch aktiven 2-substituierten carbonsäure
EP1481960A4 (de) *	2002-02-04	2005-04-06	Kaneka Corp	Verfahren zur herstellung optisch aktiver 2-halogencarbonsäuren

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4339600A (en) *	1976-05-10	1982-07-13	E. R. Squibb & Sons, Inc.	Compounds for alleviating angiotensin related hypertension
JPS56158732A (en) *	1980-05-14	1981-12-07	Toyo Soda Mfg Co Ltd	Preparation of alpha-halogeno-beta-phenylpropionic acid
FR2679564A1 (fr) *	1991-07-23	1993-01-29	Inst Nat Sante Rech Med	Nouveaux acylmercaptoalcanoldipeptides, leur preparation et les compositions qui les contiennent.
EP0640086B1 (de) *	1992-05-15	1999-08-04	Merrell Pharmaceuticals Inc.	MERCAPTOACETYLAMIDE VON PYRIDAZO[1,2-a][1,2]-DIAZEPIN -DERIVATEN ALS EUKEPHALINASE UND ACE-INHIBITOREN
US5238932A (en) *	1992-05-20	1993-08-24	Merrell Dow Pharmaceuticals Inc.	Mercaptoacetylamide tricyclic derivatives useful as inhibitors of enkephalinase
US5504080A (en) *	1992-10-28	1996-04-02	Bristol-Myers Squibb Co.	Benzo-fused lactams
US5508272A (en) *	1993-06-15	1996-04-16	Bristol-Myers Squibb Company	Compounds containing a fused bicycle ring and processes therefor
US5525723A (en) *	1993-11-18	1996-06-11	Bristol-Myers Squibb Co.	Compounds containing a fused multiple ring lactam

1998
- 1998-02-18 IT IT98MI000302A patent/IT1298268B1/it active IP Right Grant
1999
- 1999-01-26 EP EP99903680A patent/EP1056707B1/de not_active Expired - Lifetime
- 1999-01-26 IL IL13712099A patent/IL137120A/xx active IP Right Grant
- 1999-01-26 WO PCT/EP1999/000468 patent/WO1999042431A1/en active IP Right Grant
- 1999-01-26 DE DE69922792T patent/DE69922792D1/de not_active Expired - Fee Related
- 1999-01-26 CA CA002321001A patent/CA2321001A1/en not_active Abandoned
- 1999-01-26 HU HU0100253A patent/HUP0100253A3/hu unknown
- 1999-01-26 AT AT99903680T patent/ATE285393T1/de not_active IP Right Cessation
- 1999-02-02 ZA ZA9900812A patent/ZA99812B/xx unknown
- 1999-02-17 US US09/251,432 patent/US6103931A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
ATE285393T1 (de)	2005-01-15
IT1298268B1 (it)	1999-12-20
CA2321001A1 (en)	1999-08-26
IL137120A0 (en)	2001-06-14
ITMI980302A1 (it)	1999-08-18
WO1999042431A1 (en)	1999-08-26
HUP0100253A3 (en)	2002-09-30
IL137120A (en)	2005-06-19
ZA99812B (en)	1999-08-02
HUP0100253A2 (hu)	2001-05-28
US6103931A (en)	2000-08-15
EP1056707B1 (de)	2004-12-22
EP1056707A1 (de)	2000-12-06

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Legal Events

Date	Code	Title	Description
2005-11-17	8339	Ceased/non-payment of the annual fee