IL135232A - 21-hydroxy-6 19-oxidoprogesterone for treating excess of glucocorticoids - Google Patents

21-hydroxy-6 19-oxidoprogesterone for treating excess of glucocorticoids

Info

Publication number: IL135232A
Authority: IL; Israel
Prior art keywords: oxidoprogesterone; glucocorticoids; hydroxy; treating excess; excess
Prior art date: 1997-09-23

Application number

IL13523298A

Other languages

English (en)

Other versions

IL135232A0 (en

Original Assignee

Applied Research Systems

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-09-23

Filing date

1998-09-22

Publication date

2005-05-17

1998-09-22 Application filed by Applied Research Systems filed Critical Applied Research Systems

2001-05-20 Publication of IL135232A0 publication Critical patent/IL135232A0/xx

2005-05-17 Publication of IL135232A publication Critical patent/IL135232A/xx

Links

FIHWBGCIKMXLBI-NXMWLWCLSA-N (8s,9s,10s,13s,14s,17s)-17-acetyl-10-(hydroxymethyl)-13-methyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one Chemical compound C1CC2=CC(=O)CC[C@]2(CO)[C@@H]2[C@@H]1[C@@H]1CC[C@H](C(=O)C)[C@@]1(C)CC2 FIHWBGCIKMXLBI-NXMWLWCLSA-N 0.000 title 1
239000003862 glucocorticoid Substances 0.000 title 1
229940037128 systemic glucocorticoids Drugs 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- A61P5/46—Drugs for disorders of the endocrine system of the suprarenal hormones for decreasing, blocking or antagonising the activity of glucocorticosteroids

Landscapes

Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Endocrinology (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Diabetes (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

IL13523298A 1997-09-23 1998-09-22 21-hydroxy-6 19-oxidoprogesterone for treating excess of glucocorticoids IL135232A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP97116526A EP0903146A1 (en)	1997-09-23	1997-09-23	21-Hydroy-6,19-oxidoprogesterone (210h-60p) as antiglucocorticoid
PCT/EP1998/006021 WO1999015181A1 (en)	1997-09-23	1998-09-22	21-hydroxy-6,19-oxidoprogesterone (21oh-6op) and its use as medicament for treating excess of glucocorticoids

Publications (2)

Publication Number	Publication Date
IL135232A0 IL135232A0 (en)	2001-05-20
IL135232A true IL135232A (en)	2005-05-17

Family

ID=8227390

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL13523298A IL135232A (en)	1997-09-23	1998-09-22	21-hydroxy-6 19-oxidoprogesterone for treating excess of glucocorticoids

Country Status (13)

Country	Link
US (1)	US6303591B1 (xx)
EP (2)	EP0903146A1 (xx)
AR (1)	AR023008A1 (xx)
AT (1)	ATE215373T1 (xx)
AU (1)	AU738522B2 (xx)
CA (1)	CA2303817C (xx)
DE (1)	DE69804659T2 (xx)
DK (1)	DK1033990T3 (xx)
ES (1)	ES2172937T3 (xx)
IL (1)	IL135232A (xx)
PT (1)	PT1033990E (xx)
WO (1)	WO1999015181A1 (xx)
ZA (1)	ZA988674B (xx)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
MXPA01011018A (es)	1999-04-30	2002-05-06	Pfizer Prod Inc	Moduladores del receptor glucocorticoide.
US7713989B2 (en)	2000-04-27	2010-05-11	Dow Robert L	Glucocorticoid receptor modulators
ES2271090T3 (es) *	2000-09-18	2007-04-16	Applied Research Systems Ars Holding N.V.	Metodo para la preparacion de 21-hidroxi-6,19-oxidoprogesterona (21oh-60p).
PT1330468E (pt) *	2000-09-18	2007-09-13	Serono Lab	Análogos de enxofre de 21-hidroxi-6, 19-oxidoprogesterona ( 21oh-60p) para tratar excesso de glucocorticóides.
EP1201660B1 (en)	2000-10-30	2005-08-31	Pfizer Products Inc.	Glucocorticoid receptor modulators
US8097606B2 (en) *	2003-07-23	2012-01-17	Corcept Therapeutics, Inc.	Antiglucocorticoids for the treatment of catatonia
EP1886695A1 (en) *	2006-06-27	2008-02-13	Speedel Experimenta AG	Pharmaceutical combination of an aldosterone synthase inhibitor and a glucocorticoid receptor antagonist or a cortisol synthesis inhibitor or a corticotropin releasing factor antagonist
DK2054049T3 (en)	2006-08-24	2016-08-01	Univ Tennessee Res Found	SUBSTITUTED ACYLANILIDES AND PROCEDURES FOR USING THEREOF
EP2576582B1 (en)	2010-05-26	2019-09-18	Corcept Therapeutics, Inc.	Treatment of muscular dystrophy
US9744149B2 (en)	2012-07-13	2017-08-29	Gtx, Inc.	Method of treating androgen receptor (AR)-positive breast cancers with selective androgen receptor modulator (SARMs)
US10987334B2 (en)	2012-07-13	2021-04-27	University Of Tennessee Research Foundation	Method of treating ER mutant expressing breast cancers with selective androgen receptor modulators (SARMs)
US9969683B2 (en)	2012-07-13	2018-05-15	Gtx, Inc.	Method of treating estrogen receptor (ER)-positive breast cancers with selective androgen receptor modulator (SARMS)
US10314807B2 (en)	2012-07-13	2019-06-11	Gtx, Inc.	Method of treating HER2-positive breast cancers with selective androgen receptor modulators (SARMS)
US9622992B2 (en)	2012-07-13	2017-04-18	Gtx, Inc.	Method of treating androgen receptor (AR)-positive breast cancers with selective androgen receptor modulator (SARMs)
CN104754939A (zh)	2012-07-13	2015-07-01	Gtx公司	用选择性雄激素受体调节剂(sarm)治疗雄激素受体(ar)阳性乳癌的方法
US10258596B2 (en)	2012-07-13	2019-04-16	Gtx, Inc.	Method of treating HER2-positive breast cancers with selective androgen receptor modulators (SARMS)
EP3265127B1 (en)	2015-03-02	2024-02-21	Corcept Therapeutics, Inc.	Mifepristone and octreotide for use in the treatment of cushing's syndrome in a patient having an adrenocorticotropic hormone (acth)-secreting pancreatic neuroendocrine tumor
AU2016243625B2 (en)	2015-03-30	2020-09-10	Corcept Therapeutics, Inc.	Use of glucocorticoid receptor antagonists in combination with glucocorticoids to treat adrenal insufficiency
CA2994422A1 (en)	2015-08-13	2017-02-16	Corcept Therapeutics, Inc.	Method for differentially diagnosing acth-dependent cushing's syndrome
ES2861524T3 (es)	2016-01-19	2021-10-06	Corcept Therapeutics Inc	Diagnóstico diferencial del Síndrome de Cushing Ectópico
CA3065555A1 (en)	2017-06-20	2018-12-27	Corcept Therapeutics, Inc.	Methods of treating neuroepithelial tumors using selective glucocorticoid receptor modulators
JP2022515528A (ja) *	2018-12-28	2022-02-18	パンダコンサルティングエルエルシー	短時間作用型選択的糖質コルチコイド受容体モジュレーター

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL118974A (en) *	1995-08-17	2001-09-13	Akzo Nobel Nv	History 11 - (Transformed Phenyl) - Astra - 4, 9 - Diane, their preparation and pharmaceutical preparations containing them
CN1187053C (zh) *	1997-10-06	2005-02-02	利兰·斯坦福青年大学托管委员会	糖皮质素受体拮抗剂用于制造治疗精神病药物的用途

1997
- 1997-09-23 EP EP97116526A patent/EP0903146A1/en not_active Withdrawn
1998
- 1998-09-22 AT AT98956833T patent/ATE215373T1/de not_active IP Right Cessation
- 1998-09-22 DE DE69804659T patent/DE69804659T2/de not_active Expired - Fee Related
- 1998-09-22 DK DK98956833T patent/DK1033990T3/da active
- 1998-09-22 ES ES98956833T patent/ES2172937T3/es not_active Expired - Lifetime
- 1998-09-22 WO PCT/EP1998/006021 patent/WO1999015181A1/en active IP Right Grant
- 1998-09-22 PT PT98956833T patent/PT1033990E/pt unknown
- 1998-09-22 AU AU13341/99A patent/AU738522B2/en not_active Ceased
- 1998-09-22 EP EP98956833A patent/EP1033990B1/en not_active Expired - Lifetime
- 1998-09-22 ZA ZA988674A patent/ZA988674B/xx unknown
- 1998-09-22 CA CA002303817A patent/CA2303817C/en not_active Expired - Fee Related
- 1998-09-22 AR ARP980104727A patent/AR023008A1/es unknown
- 1998-09-22 IL IL13523298A patent/IL135232A/xx not_active IP Right Cessation
2000
- 2000-03-23 US US09/533,225 patent/US6303591B1/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
ATE215373T1 (de)	2002-04-15
IL135232A0 (en)	2001-05-20
DK1033990T3 (da)	2002-07-08
AR023008A1 (es)	2002-09-04
PT1033990E (pt)	2002-07-31
AU1334199A (en)	1999-04-12
EP1033990A1 (en)	2000-09-13
EP0903146A1 (en)	1999-03-24
ES2172937T3 (es)	2002-10-01
EP1033990B1 (en)	2002-04-03
CA2303817C (en)	2008-04-01
AU738522B2 (en)	2001-09-20
ZA988674B (en)	1999-06-28
DE69804659T2 (de)	2002-10-02
CA2303817A1 (en)	1999-04-01
DE69804659D1 (de)	2002-05-08
WO1999015181A1 (en)	1999-04-01
US6303591B1 (en)	2001-10-16

Legal Events

Date	Code	Title	Description
2007-03-08	NE	Application for restoration - patent lapsed through non-payment of renewal fees (section 60, patents law, 5727-1967)
2013-04-30	MM9K	Patent not in force due to non-payment of renewal fees

Publication	Publication Date	Title
IL135232A (en)	2005-05-17	21-hydroxy-6 19-oxidoprogesterone for treating excess of glucocorticoids
EP0874828A4 (en)	1999-09-01	PAIN TREATMENT COMPOSITIONS
AP9600840A0 (en)	1996-07-31	Treatment of ovarian estrogen dependent conditions
IL131484A0 (en)	2001-01-28	Treatment of cardiomyopathy
AU7582398A (en)	1998-12-11	Composition for treating skin conditions
ZA971709B (en)	1998-08-27	Method of increasing testosterone
PL338082A1 (en)	2000-09-25	Methods of treating obesity
GB9715295D0 (en)	1997-09-24	Novel method of treatment
GB9712866D0 (en)	1997-08-20	Novel method of treatment
GB9707693D0 (en)	1997-06-04	Novel method of treatment
GB9725114D0 (en)	1998-01-28	Treatment of pruritus
GB9715298D0 (en)	1997-09-24	Novel method of treatment
GB9715306D0 (en)	1997-09-24	Novel method of treatment
PL341667A1 (en)	2001-04-23	Method of treating cooped
IL124419A0 (en)	1998-12-06	Composition for treating pain
PL334803A1 (en)	2000-03-13	Derivatives of imino-aza-antracyclinone for treating amyloidosis
EP1007041A4 (en)	2001-03-07	COMPOSITION FOR TREATING PAIN
PL340430A1 (en)	2001-02-12	Combination for treating aids
AU7247898A (en)	1998-11-11	Composition for treating pain
PL335904A1 (en)	2000-05-22	Application of 7alpha-methyl-17alpha-ethynylestrane derivative for treating arteriosclerosis
EP0912178A4 (en)	2000-08-16	METHOD FOR TREATING THE HIGH PRESSURE
IL120254A0 (en)	1997-06-10	Composition for treatment of acne
PL327430A1 (en)	1999-01-18	Set of shaped components
PL313849A1 (en)	1997-10-27	Beta-aminoesters of o-hydrobenzylamides
TW359161U (en)	1999-05-21	Apparatus for safeguarding women against incontinenece of urine