IL134225A0 - Use of locally delivered metal ions for treatment of periodontal disease - Google Patents

Use of locally delivered metal ions for treatment of periodontal disease

Info

Publication number
IL134225A0
IL134225A0 IL13422598A IL13422598A IL134225A0 IL 134225 A0 IL134225 A0 IL 134225A0 IL 13422598 A IL13422598 A IL 13422598A IL 13422598 A IL13422598 A IL 13422598A IL 134225 A0 IL134225 A0 IL 134225A0
Authority
IL
Israel
Prior art keywords
treatment
metal ions
periodontal disease
locally delivered
delivered metal
Prior art date
Application number
IL13422598A
Other languages
English (en)
Original Assignee
Periodontix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Periodontix Inc filed Critical Periodontix Inc
Publication of IL134225A0 publication Critical patent/IL134225A0/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0063Periodont
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/38Silver; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/26Iron; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/30Zinc; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/34Copper; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
IL13422598A 1997-08-14 1998-08-13 Use of locally delivered metal ions for treatment of periodontal disease IL134225A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/911,413 US6153210A (en) 1997-08-14 1997-08-14 Use of locally delivered metal ions for treatment of periodontal disease
PCT/US1998/016738 WO1999008691A2 (en) 1997-08-14 1998-08-13 Use of locally delivered metal ions for treatment of periodontal disease

Publications (1)

Publication Number Publication Date
IL134225A0 true IL134225A0 (en) 2001-04-30

Family

ID=25430198

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13422598A IL134225A0 (en) 1997-08-14 1998-08-13 Use of locally delivered metal ions for treatment of periodontal disease

Country Status (9)

Country Link
US (1) US6153210A (no)
EP (1) EP1011693A1 (no)
JP (1) JP2001515042A (no)
KR (1) KR20010022825A (no)
AU (1) AU9017898A (no)
CA (1) CA2301065A1 (no)
IL (1) IL134225A0 (no)
NO (1) NO20000688L (no)
WO (1) WO1999008691A2 (no)

Families Citing this family (76)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE29908415U1 (de) * 1999-05-18 1999-07-22 Carl, Wolfgang, Dr.med.dent., 66386 St Ingbert Mittel zur Behandlung lokaler parodontaler Infektionen
EP1066825A1 (en) * 1999-06-17 2001-01-10 The Procter & Gamble Company An anti-microbial body care product
IL133473A0 (en) * 1999-12-12 2001-04-30 Avenir R & B Medical Technolog Bactericidal haemostatic preparations for local use and the methods of their production and conservation
US6551608B2 (en) * 2000-03-06 2003-04-22 Porex Technologies Corporation Porous plastic media with antiviral or antimicrobial properties and processes for making the same
WO2001091553A1 (en) * 2000-05-26 2001-12-06 Demegen, Inc. Composite wafer for controlled drug delivery
US20040191329A1 (en) * 2000-07-27 2004-09-30 Burrell Robert E. Compositions and methods of metal-containing materials
US20030180379A1 (en) * 2000-07-27 2003-09-25 Burrell Robert E. Solutions and aerosols of metal-containing compounds
US6726898B2 (en) 2000-11-17 2004-04-27 Gary R. Jernberg Local delivery of agents for disruption and inhibition of bacterial biofilm for treatment of periodontal disease
US6576226B1 (en) * 2000-11-17 2003-06-10 Gary R. Jernberg Local delivery of agents for disruption and inhibition of bacterial biofilm for treatment of periodontal disease
DE20020649U1 (de) * 2000-12-06 2002-04-11 Stryker Trauma Gmbh Vorrichtung für den chirurgischen oder therapeutischen Gebrauch, insbesondere Implantate und chirurgische Instrumente sowie deren Zubehör
US7090497B1 (en) 2001-02-21 2006-08-15 Harris David M Method of periodontal laser treatment
ES2261659T3 (es) * 2001-04-23 2006-11-16 Nucryst Pharmaceuticals Corp. Un medicamento o una preparacion que contiene un metal tal como plata, oro, platino o paladio como un agente antimicrobiano y su uso para el tratamiento de estados inflamatorios de la piel.
US7357891B2 (en) 2001-10-12 2008-04-15 Monosol Rx, Llc Process for making an ingestible film
US8900497B2 (en) 2001-10-12 2014-12-02 Monosol Rx, Llc Process for making a film having a substantially uniform distribution of components
US8663687B2 (en) * 2001-10-12 2014-03-04 Monosol Rx, Llc Film compositions for delivery of actives
US7425292B2 (en) 2001-10-12 2008-09-16 Monosol Rx, Llc Thin film with non-self-aggregating uniform heterogeneity and drug delivery systems made therefrom
US7910641B2 (en) 2001-10-12 2011-03-22 Monosol Rx, Llc PH modulated films for delivery of actives
US11207805B2 (en) 2001-10-12 2021-12-28 Aquestive Therapeutics, Inc. Process for manufacturing a resulting pharmaceutical film
US20190328679A1 (en) 2001-10-12 2019-10-31 Aquestive Therapeutics, Inc. Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
US7666337B2 (en) 2002-04-11 2010-02-23 Monosol Rx, Llc Polyethylene oxide-based films and drug delivery systems made therefrom
US8603514B2 (en) 2002-04-11 2013-12-10 Monosol Rx, Llc Uniform films for rapid dissolve dosage form incorporating taste-masking compositions
US8765167B2 (en) 2001-10-12 2014-07-01 Monosol Rx, Llc Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
US20070281003A1 (en) 2001-10-12 2007-12-06 Fuisz Richard C Polymer-Based Films and Drug Delivery Systems Made Therefrom
US10285910B2 (en) 2001-10-12 2019-05-14 Aquestive Therapeutics, Inc. Sublingual and buccal film compositions
DK2332523T4 (da) * 2001-10-12 2022-02-21 Aquestive Therapeutics Inc Ensartede film til hurtigtopløsende doseringsform indeholdende smagsmaskerende præparater
US20110033542A1 (en) 2009-08-07 2011-02-10 Monosol Rx, Llc Sublingual and buccal film compositions
US8900498B2 (en) 2001-10-12 2014-12-02 Monosol Rx, Llc Process for manufacturing a resulting multi-layer pharmaceutical film
US20040127892A1 (en) * 2002-01-31 2004-07-01 Harris David M. Periodontal laser and methods
US8017150B2 (en) 2002-04-11 2011-09-13 Monosol Rx, Llc Polyethylene oxide-based films and drug delivery systems made therefrom
KR20030084135A (ko) * 2002-04-25 2003-11-01 김형순 뮤탄스 구균 부착 억제 장치
MXPA05002589A (es) * 2002-09-05 2005-09-20 Ambrose Catherine G Microesferas antibioticas para el tratamiento de infecciones y osteomelitis.
US8986737B2 (en) * 2002-09-05 2015-03-24 Wm. Marsh Rice University Antibiotic microspheres for treatment and prevention of osteomyelitis and enhancement of bone regrowth
EP2716284A3 (en) * 2003-05-28 2014-11-05 MonoSol RX LLC Polyethylene oxide-based films and drug delivery systems made herefrom
BRPI0415742A (pt) * 2003-10-23 2006-12-19 Pfizer Producs Inc vacina para a doença periodontal
EP1531169B1 (en) * 2003-11-14 2007-06-27 The Procter & Gamble Company Polymeric compositions for sustained release of volatile materials
DE10358748A1 (de) * 2003-12-12 2005-07-14 Lts Lohmann Therapie-Systeme Ag Darreichungsform basierend auf vernetzten hydrophilen Polymeren
US7335613B2 (en) * 2004-04-08 2008-02-26 Rohm And Haas Company Fiber substrate with antibacterial finish and methods of making and using the same
US7390774B2 (en) * 2004-04-08 2008-06-24 Rohm And Haas Company Antibacterial composition and methods of making and using the same
EP1604690B1 (en) * 2004-06-08 2014-03-05 The Procter & Gamble Company Polymeric hot melt adhesive compositions for sustained release of volatile materials
EP1624013A1 (en) * 2004-08-05 2006-02-08 The Procter & Gamble Company Compositions for sustained release of volatile materials
EP1655344A1 (en) * 2004-11-05 2006-05-10 The Procter & Gamble Company Polymeric compositions for sustained release of volatile materials
EP1721621A1 (en) * 2005-05-09 2006-11-15 The Procter & Gamble Company Perfume releasing packages
US9180229B2 (en) * 2005-05-19 2015-11-10 Ethicon, Inc. Antimicrobial polymer compositions and the use thereof
US9149558B2 (en) * 2005-05-19 2015-10-06 Ethicon, Inc. Antimicrobial polymer compositions and the use thereof
DE602006000082T2 (de) * 2005-07-07 2008-05-15 Rohm And Haas Co. Faser mit antimikrobiell wirksamer Zusammensetzung
AU2006222708A1 (en) * 2005-10-07 2007-04-26 Rohm And Haas Company Method for disinfecting or sanitizing a surface
PL1795556T3 (pl) * 2005-12-07 2017-08-31 The Procter And Gamble Company Kompozycje polimerowe dla przedłużonego uwalniania lotnych substancji
EP1816165A1 (en) * 2006-02-03 2007-08-08 The Procter and Gamble Company Tackified polymeric compositions for perfume delivery
CN101516331A (zh) 2006-09-20 2009-08-26 莫诺索尔克斯有限公司 含有抗泡沫调味剂的可食用水溶性膜
EP2155145A1 (en) * 2006-12-22 2010-02-24 Marianna Cooley Dental antimicrobial formulations and methods of using the same
WO2009085651A1 (en) 2007-12-20 2009-07-09 Nucryst Pharmaceuticals Corp. Metal carbonate particles for use in medicine and methods of making thereof
US8956161B2 (en) 2008-11-04 2015-02-17 Duane C Keller Article and method for controlling oral-originated systemic disease
US8905760B2 (en) * 2008-11-04 2014-12-09 Duane C. Keller Methods and systems for progressively treating and controlling oral periopathogens causing systemic inflammations
US9192626B2 (en) * 2009-06-10 2015-11-24 American Silver, Llc Dental uses of silver hydrosol
US8475832B2 (en) 2009-08-07 2013-07-02 Rb Pharmaceuticals Limited Sublingual and buccal film compositions
CN103209681B (zh) 2010-06-10 2017-05-24 Mida科技有限公司 纳米颗粒薄膜递送***
US9149959B2 (en) 2010-10-22 2015-10-06 Monosol Rx, Llc Manufacturing of small film strips
CA2817229A1 (en) * 2010-11-08 2012-05-18 Naihong Li Gels and hydrogels
US8591229B2 (en) 2010-12-16 2013-11-26 Duane C. Keller Devices and methods for creating a positive pressure environment for treatment of oral biofilms associated with periodontal disease
SG190975A1 (en) 2010-12-23 2013-07-31 Colgate Palmolive Co Fluid compositions comprising a structuring agent
CN103260600B (zh) 2010-12-23 2015-12-02 高露洁-棕榄公司 包含黄原胶、纤维素胶和卡波姆的水性口腔护理组合物
BR112014014315B1 (pt) 2011-12-15 2018-07-03 Colgate-Palmolive Company Composição aquosa de higiene oral e uso da mesma
US8956157B2 (en) * 2012-01-31 2015-02-17 Alexander Philippovich Rutberg Apparatus and method for treatment of periodontal disease
US11000545B2 (en) 2013-03-15 2021-05-11 Cda Research Group, Inc. Copper ion compositions and methods of treatment for conditions caused by coronavirus and influenza
US11318089B2 (en) 2013-03-15 2022-05-03 Cda Research Group, Inc. Topical copper ion treatments and methods of making topical copper ion treatments for use in various anatomical areas of the body
US11083750B2 (en) 2013-03-15 2021-08-10 Cda Research Group, Inc. Methods of treatment using topical copper ion formulations
US10398733B2 (en) 2013-03-15 2019-09-03 Cda Research Group, Inc. Topical copper ion treatments and methods of treatment using topical copper ion treatments in the dermatological areas of the body
US11007143B2 (en) 2013-03-15 2021-05-18 Cda Research Group, Inc. Topical copper ion treatments and methods of treatment using topical copper ion treatments in the oral-respiratory-otic areas of the body
JP6241610B2 (ja) * 2014-02-21 2017-12-06 学校法人大阪歯科大学 口腔用組成物および動物の歯周病治療方法
TWI566783B (zh) * 2015-08-21 2017-01-21 王式禹 銀高分子漱口水
US11273131B2 (en) 2016-05-05 2022-03-15 Aquestive Therapeutics, Inc. Pharmaceutical compositions with enhanced permeation
CA3022840A1 (en) 2016-05-05 2017-11-09 Aquestive Therapeutics, Inc. Enhanced delivery epinephrine compositions
RU2693678C1 (ru) * 2018-03-19 2019-07-03 Федеральное государственное бюджетное образовательное учреждение высшего образования "Ставропольский государственный медицинский университет" Министерства здравоохранения Российской Федерации (ФГБОУ ВО СтГМУ Минздрава России) Способ лечения хронического генерализованного пародонтита
US11193184B2 (en) 2019-02-22 2021-12-07 Cda Research Group, Inc. System for use in producing a metal ion suspension and process of using same
ES2791771B2 (es) * 2019-05-03 2021-05-11 Nanomateriales Y Polimeros S L Membrana hidrófila de nanofibras no tejidas para promover la regeneración ósea
KR102260902B1 (ko) * 2019-11-28 2021-06-03 긴미라이 가부시키가이샤 은 제균성 스폰지 양치 기구, 은 제균성 칫솔 및 이의 제조방법

Family Cites Families (62)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US33093A (en) * 1861-08-20 Improvement in potato-diggers
FR882M (no) * 1961-01-18 1961-10-06
US3875937A (en) * 1963-10-31 1975-04-08 American Cyanamid Co Surgical dressings of absorbable polymers
US3739773A (en) * 1963-10-31 1973-06-19 American Cyanamid Co Polyglycolic acid prosthetic devices
US3419006A (en) * 1966-08-08 1968-12-31 Union Carbide Corp Novel dressing and use thereof
US3639575A (en) * 1968-06-19 1972-02-01 Basf Wyandotte Corp Silver ion gel compositions and method of using the same
DE2811522C2 (de) * 1978-03-16 1979-11-29 Dr. Eduard Fresenius, Chemisch- Pharmazeutische Industrie Kg, 6380 Bad Homburg Zahnpflegemittel
EP0048246B1 (en) * 1980-03-27 1986-05-28 National Research Development Corporation Antimicrobial surgical implants
US4376764A (en) * 1981-08-10 1983-03-15 Basf Wyandotte Corporation Silver ion gel compositions
US4570629A (en) * 1982-03-17 1986-02-18 University Of Illinois Foundation Hydrophilic biopolymeric copolyelectrolytes, and biodegradable wound dressing comprising same
US4588400A (en) * 1982-12-16 1986-05-13 Johnson & Johnson Products, Inc. Liquid loaded pad for medical applications
US4559223A (en) * 1983-05-20 1985-12-17 Daltex Medical Sciences, Inc. Silver sulfadiazine and/or zinc sulfadiazine-containing toothpaste or oral medicament
JPS59222406A (ja) * 1983-06-01 1984-12-14 Teijin Ltd 歯周疾患治療用製剤及びその製造法
US4685883A (en) * 1983-09-12 1987-08-11 Jernberg Gary R Local delivery of chemotherapeutic agents for the treatment of periodontal disease
US4764377A (en) * 1983-10-07 1988-08-16 The Forsyth Dental Infirmary For Children Intra-pocket drug delivery devices for treatment of periodontal diseases
US4892736A (en) * 1983-10-07 1990-01-09 The Forsyth Dental Infirmary For Children Intra-pocket drug delivery devices for treatment of periodontal diseases
US5571521A (en) * 1984-01-16 1996-11-05 Lasker; Sigmund E. Composition containing silver ammonium phenytoin complex and a phenytoin and use of said composition
US4847049A (en) * 1985-12-18 1989-07-11 Vitaphore Corporation Method of forming chelated collagen having bactericidal properties
JPS62223115A (ja) * 1986-03-25 1987-10-01 Rooto Seiyaku Kk 歯周病治療剤
JPS62223112A (ja) * 1986-03-25 1987-10-01 Rooto Seiyaku Kk 歯周病治療剤
JPH0759496B2 (ja) * 1986-03-25 1995-06-28 ロ−ト製薬株式会社 歯周病治療剤
US4780320A (en) * 1986-04-29 1988-10-25 Pharmetrix Corp. Controlled release drug delivery system for the periodontal pocket
US4919939A (en) * 1986-04-29 1990-04-24 Pharmetrix Corporation Periodontal disease treatment system
IL78826A (en) * 1986-05-19 1991-05-12 Yissum Res Dev Co Precursor composition for the preparation of a biodegradable implant for the sustained release of an active material and such implants prepared therefrom
USRE33093E (en) 1986-06-16 1989-10-17 Johnson & Johnson Consumer Products, Inc. Bioadhesive extruded film for intra-oral drug delivery and process
US4713243A (en) * 1986-06-16 1987-12-15 Johnson & Johnson Products, Inc. Bioadhesive extruded film for intra-oral drug delivery and process
US4728323A (en) * 1986-07-24 1988-03-01 Minnesota Mining And Manufacturing Company Antimicrobial wound dressings
DE3751254D1 (de) * 1986-10-31 1995-05-24 Nippon Zeon Co Wundverband.
US4846165A (en) * 1986-11-26 1989-07-11 Dentsply Research & Development Corp. Wound dressing membrane
US4808402A (en) * 1987-05-29 1989-02-28 Northwestern University Method and compositions for modulating neovascularization
US4978391A (en) * 1987-11-13 1990-12-18 Dentsply Management Corp. Intraoral medicament delivery and procedure
US5019096A (en) * 1988-02-11 1991-05-28 Trustees Of Columbia University In The City Of New York Infection-resistant compositions, medical devices and surfaces and methods for preparing and using same
US5387419A (en) * 1988-03-31 1995-02-07 The University Of Michigan System for controlled release of antiarrhythmic agents
DE3831657A1 (de) * 1988-09-17 1990-03-22 Boehringer Ingelheim Kg Vorrichtung zur osteosynthese und verfahren zu ihrer herstellung
US5009898A (en) * 1988-09-29 1991-04-23 Kabushiki Kaisha Sangi Antimicrobial hydroxyapatite powders and methods for preparing them
US5236355A (en) * 1988-12-22 1993-08-17 American Cyanamid Company Apparatus for the treatment of periodontal disease
DE68915132T2 (de) * 1988-12-22 1994-12-08 American Cyanamid Co., Wayne, N.J. Verfahren zur Behandlung von Periodontitis durch protrahierte Wirkstoffabgabe von Arzneimitteln in der Zahnhöhle, Zusammensetzung davon und Vorrichtung zur Verabreichung.
JPH0768109B2 (ja) * 1989-01-10 1995-07-26 株式会社オブジェ科学研究所 歯磨組成物
JP2719671B2 (ja) * 1989-07-11 1998-02-25 日本ゼオン株式会社 創傷被覆材
US5077049A (en) * 1989-07-24 1991-12-31 Vipont Pharmaceutical, Inc. Biodegradable system for regenerating the periodontium
US5059123A (en) * 1990-05-14 1991-10-22 Jernberg Gary R Periodontal barrier and method for aiding periodontal tissue regeneration
US5197882A (en) * 1990-05-14 1993-03-30 Gary R. Jernberg Periodontal barrier and method for aiding periodontal tissue regeneration agents
US5102666A (en) * 1990-09-11 1992-04-07 Oramed, Inc. Calcium polycarbophil controlled release composition and method
US5620700A (en) * 1990-10-30 1997-04-15 Alza Corporation Injectable drug delivery system and method
WO1992007555A1 (en) * 1990-10-30 1992-05-14 Alza Corporation Drug delivery system and method
BR9205879A (pt) * 1991-04-10 1994-07-05 Christopher C Capelli Composição antimicrobiana, composição adesiva, processo de tratamento de infecção em mamífero e processo para conferir proteção antimicrobiana a um paciente
GB9107833D0 (en) * 1991-04-12 1991-05-29 Unilever Plc Treatment of periodontitis
US5340581A (en) * 1991-08-23 1994-08-23 Gillette Canada, Inc. Sustained-release matrices for dental application
US5468489A (en) * 1991-10-29 1995-11-21 Sangi Co., Ltd. Dentifrice containing antibacterial material
US5260066A (en) * 1992-01-16 1993-11-09 Srchem Incorporated Cryogel bandage containing therapeutic agent
US5298237A (en) * 1992-01-24 1994-03-29 The Trustees Of Columbia University In The City Of New York Gel composition for reduction of gingival inflammation and retardation of dental plaque
US5656297A (en) * 1992-03-12 1997-08-12 Alkermes Controlled Therapeutics, Incorporated Modulated release from biocompatible polymers
GB9210947D0 (en) * 1992-05-22 1992-07-08 Boots Co Plc Oral hygiene composition
US5688492A (en) * 1992-05-22 1997-11-18 The Boots Company Plc, Oral hygiene composition
US5534288A (en) * 1993-03-23 1996-07-09 United States Surgical Corporation Infection-resistant surgical devices and methods of making them
RU2078559C1 (ru) * 1993-07-05 1997-05-10 Семен Евстафьевич Манойлов Способ лечения пародонтоза
JPH06154030A (ja) * 1993-07-06 1994-06-03 Dentaru Kagaku Kk 抗菌性アパタイトおよびそれを含有する抗菌性樹脂
US5534243A (en) * 1994-09-26 1996-07-09 The Procter & Gamble Company Aqueous oral compositions
US5707962A (en) * 1994-09-28 1998-01-13 Gensci Regeneration Sciences Inc. Compositions with enhanced osteogenic potential, method for making the same and therapeutic uses thereof
CZ282292B6 (cs) * 1995-02-24 1997-06-11 Odbor Správy Majetku Mo Farmaceutický antimikrobiální přípravek
GB9522314D0 (en) * 1995-11-01 1996-01-03 Bristol Myers Squibb Co Water soluble films
US5955097A (en) * 1996-10-18 1999-09-21 Virotex Corporation Pharmaceutical preparation applicable to mucosal surfaces and body tissues

Also Published As

Publication number Publication date
US6153210A (en) 2000-11-28
WO1999008691A2 (en) 1999-02-25
EP1011693A1 (en) 2000-06-28
KR20010022825A (ko) 2001-03-26
WO1999008691A3 (en) 1999-05-06
AU9017898A (en) 1999-03-08
JP2001515042A (ja) 2001-09-18
WO1999008691A8 (en) 2000-04-20
NO20000688L (no) 2000-03-15
CA2301065A1 (en) 1999-02-25
NO20000688D0 (no) 2000-02-11

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