IL128094A0 - Fusion polypeptides comprising an ige-binding domain and a hsa component and their diagnostic and therapeutic uses - Google Patents

Fusion polypeptides comprising an ige-binding domain and a hsa component and their diagnostic and therapeutic uses

Info

Publication number
IL128094A0
IL128094A0 IL12809497A IL12809497A IL128094A0 IL 128094 A0 IL128094 A0 IL 128094A0 IL 12809497 A IL12809497 A IL 12809497A IL 12809497 A IL12809497 A IL 12809497A IL 128094 A0 IL128094 A0 IL 128094A0
Authority
IL
Israel
Prior art keywords
ige
diagnostic
binding domain
fusion polypeptides
therapeutic uses
Prior art date
Application number
IL12809497A
Other languages
English (en)
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of IL128094A0 publication Critical patent/IL128094A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/64—General methods for preparing the vector, for introducing it into the cell or for selecting the vector-containing host
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C07K14/765—Serum albumin, e.g. HSA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70535—Fc-receptors, e.g. CD16, CD32, CD64 (CD2314/705F)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
IL12809497A 1996-07-26 1997-07-25 Fusion polypeptides comprising an ige-binding domain and a hsa component and their diagnostic and therapeutic uses IL128094A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US69021696A 1996-07-26 1996-07-26
PCT/EP1997/004066 WO1998004718A1 (en) 1996-07-26 1997-07-25 Fusion polypeptides comprising an ige-binding domain and a hsa component, and their diagnostic and therapeutic uses

Publications (1)

Publication Number Publication Date
IL128094A0 true IL128094A0 (en) 1999-11-30

Family

ID=24771594

Family Applications (2)

Application Number Title Priority Date Filing Date
IL12809497A IL128094A0 (en) 1996-07-26 1997-07-25 Fusion polypeptides comprising an ige-binding domain and a hsa component and their diagnostic and therapeutic uses
IL128094A IL128094A (en) 1996-07-26 1999-01-18 Coupled polypeptides containing the IGE binding region and the HSA component and their use in diagnosis and healing

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL128094A IL128094A (en) 1996-07-26 1999-01-18 Coupled polypeptides containing the IGE binding region and the HSA component and their use in diagnosis and healing

Country Status (28)

Country Link
EP (1) EP0917581B1 (xx)
JP (1) JP3681402B2 (xx)
KR (1) KR100502879B1 (xx)
CN (1) CN1146664C (xx)
AR (1) AR008077A1 (xx)
AT (1) ATE383429T1 (xx)
AU (1) AU722069B2 (xx)
BR (1) BR9710605A (xx)
CA (1) CA2261562C (xx)
CO (1) CO4650184A1 (xx)
CZ (1) CZ297634B6 (xx)
DE (1) DE69738452T2 (xx)
ES (1) ES2300114T3 (xx)
HK (1) HK1020352A1 (xx)
ID (1) ID19420A (xx)
IL (2) IL128094A0 (xx)
MY (1) MY120425A (xx)
NO (1) NO323611B1 (xx)
NZ (1) NZ333908A (xx)
PE (1) PE99498A1 (xx)
PL (1) PL189415B1 (xx)
PT (1) PT917581E (xx)
RU (1) RU2209211C2 (xx)
SK (1) SK7799A3 (xx)
TR (1) TR199900155T2 (xx)
TW (1) TW565571B (xx)
WO (1) WO1998004718A1 (xx)
ZA (1) ZA976666B (xx)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1056471A4 (en) * 1998-01-29 2001-05-30 Tanox Inc TREATMENT OF ATOPIC DERMATITIS USING IgE ANTAGONISTS
JP4087563B2 (ja) * 1998-06-15 2008-05-21 ジーティーシー バイオセラピューティックス インコーポレイテッド エリスロポエチン類似体−ヒト血清アルブミン融合物
JP2003506074A (ja) * 1999-08-09 2003-02-18 ジェネッサンス ファーマシューティカルズ，インコーポレイティド 薬剤標的同質遺伝子：免疫グロブリンｅ受容体ｉａｌｐｈａサブユニット遺伝子における多型
DE10026998A1 (de) * 2000-05-31 2001-12-13 Fresenius Kabi De Gmbh Verfahren zur Herstellung einer kosmetischen Zusammensetzung, die humanes Serum Albumin umfasst, welches aus transgenen nicht-menschlichen Säugern erhalten wurde
KR20080085082A (ko) 2000-12-07 2008-09-22 일라이 릴리 앤드 캄파니 Ｇｌｐ-1 융합 단백질
TW200526779A (en) * 2001-02-08 2005-08-16 Wyeth Corp Modified and stabilized GDF propeptides and uses thereof
EP1997829A1 (en) 2001-12-21 2008-12-03 Human Genome Sciences, Inc. Albumin fusion proteins
BRPI0921586A2 (pt) 2008-11-18 2019-09-24 Merrimack Pharmaceuticals Inc articuladores de albumina de soro humana e conjugados destes
US8962274B2 (en) * 2009-02-27 2015-02-24 Novartis Ag Methods for selecting eukaryotic cells expressing a heterologous protein
WO2012169735A2 (ko) * 2011-06-07 2012-12-13 (주)네오팜 FCεRI의 수용성 단편을 포함하는 복합체 및 이를 포함하는 IGE 매개 알레르기성 질환 치료용 조성물
RU2506271C2 (ru) * 2011-06-22 2014-02-10 Учреждение Российской Академии Медицинских Наук Научно-исследовательский институт экспериментальной медицины Северо-западного отделения РАМН (НИИЭМ СЗО РАМН) РЕКОМБИНАНТНЫЙ ПОЛИПЕПТИД А2, СЕЛЕКТИВНО СВЯЗЫВАЮЩИЙ HSA, РЕКОМБИНАНТНАЯ ДНК pa2, КОДИРУЮЩАЯ HSA-СВЯЗЫВАЮЩУЮ ЧАСТЬ ПОЛИПЕПТИДА A2, ЕГО ПРОДУЦЕНТ - РЕКОМБИНАНТНЫЙ ШТАММ Escherichia coli M15-A2, СОДЕРЖАЩИЙ РЕКОМБИНАНТНУЮ ПЛАЗМИДНУЮ ДНК pQE 32-pa2, ОБЕСПЕЧИВАЮЩУЮ ПОЛУЧЕНИЕ ПОЛИПЕПТИДА A2 И ПРИМЕНЕНИЕ ПОЛИПЕПТИДА А2 ДЛЯ ДИАГНОСТИКИ МИКРОАЛЬБУМИНУРИИ И ВЫДЕЛЕНИЯ HSA ИЗ СЫВОРОТКИ КРОВИ
WO2014036520A1 (en) 2012-08-30 2014-03-06 Merrimack Pharmaceuticals, Inc. Combination therapies comprising anti-erbb3 agents
US20180139938A1 (en) * 2015-05-04 2018-05-24 Laboratoire Français du Fractionnement et des, Biotechnologies Transgenic production of fc fusion proteins
EP3192806A1 (en) 2016-01-13 2017-07-19 Affiris AG Alpha chain of the high-affinity ige receptor (fceria)
CA3041717A1 (en) * 2016-11-09 2018-05-17 North Carolina State University Treatment of allergic diseases with chimeric protein
US12060437B2 (en) 2018-03-23 2024-08-13 North Carolina State University Methods and compositions for antibody to high affinity receptor for IgE
CN114302891A (zh) * 2019-07-08 2022-04-08 普罗根有限公司 新的il-10变体蛋白及其用途
CN111773392B (zh) * 2020-05-25 2023-04-07 河南省生物工程技术研究中心 一种人血白蛋白/寡核苷酸纳米颗粒及其制备方法和用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4962035A (en) * 1987-12-01 1990-10-09 President And Fellows Of Harvard College DNA encoding IgE receptor alpha-subunit or fragment thereof
GB8909916D0 (en) * 1989-04-29 1989-06-14 Delta Biotechnology Ltd Polypeptides
CA2059842A1 (en) * 1991-02-11 1992-08-12 Richard A. Chizzonite Ige-receptor-antibodies

Also Published As

Publication number Publication date
TW565571B (en) 2003-12-11
EP0917581B1 (en) 2008-01-09
NO323611B1 (no) 2007-06-18
NZ333908A (en) 1999-10-28
TR199900155T2 (xx) 2000-08-21
KR100502879B1 (ko) 2005-07-25
CZ24699A3 (cs) 1999-04-14
CZ297634B6 (cs) 2007-02-21
PT917581E (pt) 2008-04-11
NO990328L (no) 1999-02-19
IL128094A (en) 2006-08-20
RU2209211C2 (ru) 2003-07-27
PE99498A1 (es) 1999-01-21
NO990328D0 (no) 1999-01-25
CO4650184A1 (es) 1998-09-03
PL331356A1 (en) 1999-07-05
EP0917581A1 (en) 1999-05-26
CA2261562A1 (en) 1998-02-05
SK7799A3 (en) 1999-07-12
AU4202597A (en) 1998-02-20
ID19420A (id) 1998-07-09
MY120425A (en) 2005-10-31
WO1998004718A1 (en) 1998-02-05
ATE383429T1 (de) 2008-01-15
ZA976666B (en) 1999-01-25
CN1146664C (zh) 2004-04-21
JP2000516089A (ja) 2000-12-05
HK1020352A1 (en) 2000-04-14
JP3681402B2 (ja) 2005-08-10
DE69738452D1 (de) 2008-02-21
PL189415B1 (pl) 2005-08-31
ES2300114T3 (es) 2008-06-01
CN1229439A (zh) 1999-09-22
CA2261562C (en) 2011-04-05
KR20000029563A (ko) 2000-05-25
BR9710605A (pt) 1999-08-17
DE69738452T2 (de) 2008-12-24
AU722069B2 (en) 2000-07-20
AR008077A1 (es) 1999-12-09

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