IL123379A0 - Microporation of human skin for drug delivery and monitoring applications - Google Patents
Microporation of human skin for drug delivery and monitoring applicationsInfo
- Publication number
- IL123379A0 IL123379A0 IL12337996A IL12337996A IL123379A0 IL 123379 A0 IL123379 A0 IL 123379A0 IL 12337996 A IL12337996 A IL 12337996A IL 12337996 A IL12337996 A IL 12337996A IL 123379 A0 IL123379 A0 IL 123379A0
- Authority
- IL
- Israel
- Prior art keywords
- microporation
- drug delivery
- human skin
- monitoring applications
- monitoring
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/14507—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood
- A61B5/1451—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid
- A61B5/14514—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid using means for aiding extraction of interstitial fluid, e.g. microneedles or suction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B10/0045—Devices for taking samples of body liquids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0047—Sonopheresis, i.e. ultrasonically-enhanced transdermal delivery, electroporation of a pharmacologically active agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/32—Surgical cutting instruments
- A61B17/3203—Fluid jet cutting instruments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
- A61B18/20—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
- A61B18/20—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
- A61B18/203—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser applying laser energy to the outside of the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00017—Electrical control of surgical instruments
- A61B2017/00137—Details of operation mode
- A61B2017/00154—Details of operation mode pulsed
- A61B2017/00172—Pulse trains, bursts, intermittent continuous operation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00743—Type of operation; Specification of treatment sites
- A61B2017/00747—Dermatology
- A61B2017/00761—Removing layer of skin tissue, e.g. wrinkles, scars or cancerous tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00743—Type of operation; Specification of treatment sites
- A61B2017/00747—Dermatology
- A61B2017/00765—Decreasing the barrier function of skin tissue by radiated energy, e.g. using ultrasound, using laser for skin perforation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
- A61B2018/00452—Skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
- A61B2018/00452—Skin
- A61B2018/0047—Upper parts of the skin, e.g. skin peeling or treatment of wrinkles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1486—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using enzyme electrodes, e.g. with immobilised oxidase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0092—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin using ultrasonic, sonic or infrasonic vibrations, e.g. phonophoresis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Physics & Mathematics (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Heart & Thoracic Surgery (AREA)
- Pathology (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Optics & Photonics (AREA)
- Hematology (AREA)
- Measuring And Recording Apparatus For Diagnosis (AREA)
- Surgical Instruments (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Laser Surgery Devices (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US52054795A | 1995-08-29 | 1995-08-29 | |
US804395P | 1995-10-30 | 1995-10-30 | |
PCT/US1996/013865 WO1997007734A1 (en) | 1995-08-29 | 1996-08-29 | Microporation of human skin for drug delivery and monitoring applications |
Publications (2)
Publication Number | Publication Date |
---|---|
IL123379A0 true IL123379A0 (en) | 1998-09-24 |
IL123379A IL123379A (en) | 2002-04-21 |
Family
ID=26677684
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL12337996A IL123379A (en) | 1995-08-29 | 1996-08-29 | Microporation of human skin for drug delivery and monitoring applications |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP0858285A4 (en) |
JP (2) | JP3899427B2 (en) |
CN (1) | CN1174713C (en) |
AU (1) | AU707065B2 (en) |
BR (1) | BR9610012A (en) |
CA (1) | CA2199002C (en) |
ES (1) | ES2536459T3 (en) |
GB (1) | GB2307414B (en) |
HK (1) | HK1009321A1 (en) |
IL (1) | IL123379A (en) |
NO (1) | NO334437B1 (en) |
PT (1) | PT1563788E (en) |
TR (1) | TR199800347T1 (en) |
WO (1) | WO1997007734A1 (en) |
Families Citing this family (102)
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ES2195151T3 (en) | 1996-06-18 | 2003-12-01 | Alza Corp | IMPROVEMENT OR SAMPLING DEVICE FOR TRANSDERMAL AGENTS. |
US6183434B1 (en) * | 1996-07-03 | 2001-02-06 | Spectrx, Inc. | Multiple mechanical microporation of skin or mucosa |
ATE231015T1 (en) * | 1996-09-17 | 2003-02-15 | Deka Products Lp | SYSTEM FOR DELIVERY OF MEDICATION THROUGH TRANSPORT |
US20060002949A1 (en) | 1996-11-14 | 2006-01-05 | Army Govt. Of The Usa, As Rep. By Secretary Of The Office Of The Command Judge Advocate, Hq Usamrmc. | Transcutaneous immunization without heterologous adjuvant |
DK1314400T3 (en) * | 1996-12-31 | 2007-10-15 | Altea Therapeutics Corp | Microporation of tissues for delivery of bioactive agents |
US6527716B1 (en) | 1997-12-30 | 2003-03-04 | Altea Technologies, Inc. | Microporation of tissue for delivery of bioactive agents |
US6027496A (en) * | 1997-03-25 | 2000-02-22 | Abbott Laboratories | Removal of stratum corneum by means of light |
JP4338307B2 (en) | 1997-10-21 | 2009-10-07 | アボット・ラボラトリーズ | Apparatus and method for collecting interstitial fluid |
US6155992A (en) * | 1997-12-02 | 2000-12-05 | Abbott Laboratories | Method and apparatus for obtaining interstitial fluid for diagnostic tests |
US6918901B1 (en) | 1997-12-10 | 2005-07-19 | Felix Theeuwes | Device and method for enhancing transdermal agent flux |
DK1037686T3 (en) * | 1997-12-11 | 2006-01-02 | Alza Corp | Apparatus for enhancing transdermal flow of agents |
ATE221400T1 (en) * | 1997-12-11 | 2002-08-15 | Alza Corp | DEVICE FOR INCREASE THE TRANSDERMAL FLOW OF ACTIVE INGREDIENTS |
EP1037687B8 (en) | 1997-12-11 | 2008-10-22 | Alza Corporation | Device for enhancing transdermal agent flux |
US6530915B1 (en) | 1998-03-06 | 2003-03-11 | Spectrx, Inc. | Photothermal structure for biomedical applications, and method therefor |
US6173202B1 (en) * | 1998-03-06 | 2001-01-09 | Spectrx, Inc. | Method and apparatus for enhancing flux rates of a fluid in a microporated biological tissue |
ATE375752T1 (en) * | 1998-03-06 | 2007-11-15 | Spectrx Inc | INTEGRATED TISSUE PORATION, FLUID COLLECTION AND ANALYSIS DEVICE |
US6091975A (en) * | 1998-04-01 | 2000-07-18 | Alza Corporation | Minimally invasive detecting device |
US6569157B1 (en) * | 1998-05-18 | 2003-05-27 | Abbott Laboratories | Removal of stratum corneum by means of light |
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US6503231B1 (en) | 1998-06-10 | 2003-01-07 | Georgia Tech Research Corporation | Microneedle device for transport of molecules across tissue |
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CN114343839A (en) * | 2021-12-30 | 2022-04-15 | 德州环球之光医疗科技有限公司 | Treatment pattern conversion method based on adjustable spiral line type laser spots |
Family Cites Families (18)
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US4775361A (en) * | 1986-04-10 | 1988-10-04 | The General Hospital Corporation | Controlled removal of human stratum corneum by pulsed laser to enhance percutaneous transport |
US4863970A (en) * | 1986-11-14 | 1989-09-05 | Theratech, Inc. | Penetration enhancement with binary system of oleic acid, oleins, and oleyl alcohol with lower alcohols |
ATE131081T1 (en) * | 1988-01-21 | 1995-12-15 | Massachusetts Inst Technology | MOLECULAR TRANSPORT THROUGH TISSUES USING ELECTROPORATION. |
US5139023A (en) | 1989-06-02 | 1992-08-18 | Theratech Inc. | Apparatus and method for noninvasive blood glucose monitoring |
US5016615A (en) * | 1990-02-20 | 1991-05-21 | Riverside Research Institute | Local application of medication with ultrasound |
US5115805A (en) * | 1990-02-23 | 1992-05-26 | Cygnus Therapeutic Systems | Ultrasound-enhanced delivery of materials into and through the skin |
GB9014307D0 (en) * | 1990-06-27 | 1990-08-15 | Scient Generics Ltd | Method of treatment and compositions therefor |
JP3189337B2 (en) * | 1991-11-08 | 2001-07-16 | 日本電気株式会社 | Skin stratum corneum removal device and method |
US5344418A (en) * | 1991-12-12 | 1994-09-06 | Shahriar Ghaffari | Optical system for treatment of vascular lesions |
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US5267985A (en) * | 1993-02-11 | 1993-12-07 | Trancell, Inc. | Drug delivery by multiple frequency phonophoresis |
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US5445611A (en) * | 1993-12-08 | 1995-08-29 | Non-Invasive Monitoring Company (Nimco) | Enhancement of transdermal delivery with ultrasound and chemical enhancers |
JPH10509632A (en) * | 1995-07-25 | 1998-09-22 | マサチューセッツ インスティチュート オブ テクノロジー | Enhanced transdermal delivery using ultrasound |
-
1996
- 1996-08-29 IL IL12337996A patent/IL123379A/en not_active IP Right Cessation
- 1996-08-29 CA CA002199002A patent/CA2199002C/en not_active Expired - Lifetime
- 1996-08-29 EP EP96929098A patent/EP0858285A4/en not_active Withdrawn
- 1996-08-29 TR TR1998/00347T patent/TR199800347T1/en unknown
- 1996-08-29 CN CNB961966718A patent/CN1174713C/en not_active Expired - Lifetime
- 1996-08-29 ES ES05011002.2T patent/ES2536459T3/en not_active Expired - Lifetime
- 1996-08-29 WO PCT/US1996/013865 patent/WO1997007734A1/en not_active Application Discontinuation
- 1996-08-29 AU AU68631/96A patent/AU707065B2/en not_active Expired
- 1996-08-29 PT PT50110022T patent/PT1563788E/en unknown
- 1996-08-29 GB GB9702766A patent/GB2307414B/en not_active Expired - Lifetime
- 1996-08-29 BR BR9610012-5A patent/BR9610012A/en not_active Application Discontinuation
- 1996-08-29 JP JP51055297A patent/JP3899427B2/en not_active Expired - Lifetime
-
1998
- 1998-02-27 NO NO19980878A patent/NO334437B1/en not_active IP Right Cessation
- 1998-08-24 HK HK98110113A patent/HK1009321A1/en not_active IP Right Cessation
-
2006
- 2006-02-15 JP JP2006038655A patent/JP2006192285A/en not_active Withdrawn
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AU6863196A (en) | 1997-03-19 |
PT1563788E (en) | 2015-06-02 |
HK1009321A1 (en) | 1999-05-28 |
CN1174713C (en) | 2004-11-10 |
GB2307414A (en) | 1997-05-28 |
CA2199002A1 (en) | 1997-03-01 |
GB9702766D0 (en) | 1997-04-02 |
WO1997007734A1 (en) | 1997-03-06 |
EP0858285A1 (en) | 1998-08-19 |
JPH11511360A (en) | 1999-10-05 |
IL123379A (en) | 2002-04-21 |
NO334437B1 (en) | 2014-03-03 |
JP3899427B2 (en) | 2007-03-28 |
NO980878L (en) | 1998-04-27 |
NO980878D0 (en) | 1998-02-27 |
EP0858285A4 (en) | 2000-05-17 |
GB2307414B (en) | 1998-03-11 |
TR199800347T1 (en) | 1998-05-21 |
BR9610012A (en) | 1999-12-21 |
JP2006192285A (en) | 2006-07-27 |
ES2536459T3 (en) | 2015-05-25 |
AU707065B2 (en) | 1999-07-01 |
CA2199002C (en) | 1999-02-23 |
CN1195276A (en) | 1998-10-07 |
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