IL122385A - Composition for sustained release of human growth hormone - Google Patents
Composition for sustained release of human growth hormoneInfo
- Publication number
- IL122385A IL122385A IL12238596A IL12238596A IL122385A IL 122385 A IL122385 A IL 122385A IL 12238596 A IL12238596 A IL 12238596A IL 12238596 A IL12238596 A IL 12238596A IL 122385 A IL122385 A IL 122385A
- Authority
- IL
- Israel
- Prior art keywords
- composition
- sustained release
- hgh
- biologically active
- polymer
- Prior art date
Links
- 102000002265 Human Growth Hormone Human genes 0.000 title abstract 9
- 108010000521 Human Growth Hormone Proteins 0.000 title abstract 9
- 239000000854 Human Growth Hormone Substances 0.000 title abstract 9
- 239000000203 mixture Substances 0.000 title abstract 9
- 238000013268 sustained release Methods 0.000 title abstract 7
- 239000012730 sustained-release form Substances 0.000 title abstract 7
- 238000000034 method Methods 0.000 abstract 6
- 239000002245 particle Substances 0.000 abstract 4
- 229920000642 polymer Polymers 0.000 abstract 4
- 229920000249 biocompatible polymer Polymers 0.000 abstract 3
- 230000036765 blood level Effects 0.000 abstract 2
- 239000011159 matrix material Substances 0.000 abstract 2
- 230000002459 sustained effect Effects 0.000 abstract 2
- 239000006185 dispersion Substances 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/27—Growth hormone [GH], i.e. somatotropin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1611—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Endocrinology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nanotechnology (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Medical Informatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Crystallography & Structural Chemistry (AREA)
- Zoology (AREA)
- Inorganic Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/473,544 US5654010A (en) | 1992-12-02 | 1995-06-07 | Composition for sustained release of human growth hormone |
US08/477,725 US5667808A (en) | 1992-12-02 | 1995-06-07 | Composition for sustained release of human growth hormone |
PCT/US1996/008086 WO1996040072A2 (en) | 1995-06-07 | 1996-06-03 | Composition for sustained release of human growth hormone |
Publications (2)
Publication Number | Publication Date |
---|---|
IL122385A0 IL122385A0 (en) | 1998-06-15 |
IL122385A true IL122385A (en) | 2001-01-11 |
Family
ID=27044171
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL12238596A IL122385A (en) | 1995-06-07 | 1996-06-03 | Composition for sustained release of human growth hormone |
Country Status (22)
Country | Link |
---|---|
EP (1) | EP0831787B1 (sk) |
JP (1) | JPH11506740A (sk) |
CN (1) | CN1102854C (sk) |
AT (1) | ATE204468T1 (sk) |
AU (1) | AU708756B2 (sk) |
BR (1) | BR9608542A (sk) |
CA (1) | CA2223436A1 (sk) |
CZ (1) | CZ288147B6 (sk) |
DE (1) | DE69614685T2 (sk) |
DK (1) | DK0831787T3 (sk) |
ES (1) | ES2161366T3 (sk) |
HK (1) | HK1009089A1 (sk) |
HU (1) | HUP9900870A3 (sk) |
IL (1) | IL122385A (sk) |
MX (1) | MX9709698A (sk) |
NO (1) | NO316104B1 (sk) |
NZ (1) | NZ310644A (sk) |
PL (1) | PL184531B1 (sk) |
PT (1) | PT831787E (sk) |
RU (1) | RU2161502C2 (sk) |
SK (1) | SK281571B6 (sk) |
WO (1) | WO1996040072A2 (sk) |
Families Citing this family (95)
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WO1997001331A2 (en) * | 1995-06-27 | 1997-01-16 | Takeda Chemical Industries, Ltd. | Method of producing sustained-release preparation |
EP0946169B1 (en) | 1996-12-20 | 2003-02-26 | Takeda Chemical Industries, Ltd. | Method of producing a sustained-release preparation |
MY118835A (en) * | 1997-04-18 | 2005-01-31 | Ipsen Pharma Biotech | Sustained release compositions and the process for their preparation |
US6306826B1 (en) | 1997-06-04 | 2001-10-23 | The Regents Of The University Of California | Treatment of heart failure with growth hormone |
US6663899B2 (en) | 1997-06-13 | 2003-12-16 | Genentech, Inc. | Controlled release microencapsulated NGF formulation |
US6113947A (en) * | 1997-06-13 | 2000-09-05 | Genentech, Inc. | Controlled release microencapsulated NGF formulation |
US6191107B1 (en) | 1997-09-26 | 2001-02-20 | Takeda Chemical Industries, Ltd. | Complex of human growth hormone and zinc |
NZ525914A (en) | 1998-03-10 | 2004-03-26 | Genentech Inc | Novel polypeptides and nucleic acids encoding the same |
IL138930A0 (en) | 1998-05-15 | 2001-11-25 | Genentech Inc | Il-17 homologies polypeptides and therapeutic uses thereof |
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US20020172678A1 (en) | 2000-06-23 | 2002-11-21 | Napoleone Ferrara | EG-VEGF nucleic acids and polypeptides and methods of use |
EP1953173B1 (en) | 1999-06-15 | 2009-11-18 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids endoding the same |
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EP1897947B1 (en) | 1999-12-23 | 2012-01-18 | Genentech, Inc. | IL-17 homologous polypeptides and therapeutic uses thereof |
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---|---|---|---|---|
US5656297A (en) * | 1992-03-12 | 1997-08-12 | Alkermes Controlled Therapeutics, Incorporated | Modulated release from biocompatible polymers |
DE69329295T2 (de) * | 1992-12-02 | 2001-03-15 | Alkermes Controlled Therapeutics, Inc. | Wachstumhormon enthaltende mikrosphaeren mit kontrollierter freisetzung |
ES2151079T3 (es) * | 1994-09-09 | 2000-12-16 | Takeda Chemical Industries Ltd | Preparacion de liberacion sostenida que contiene una sal metalica de un peptido. |
-
1996
- 1996-06-03 RU RU97119935/14A patent/RU2161502C2/ru not_active IP Right Cessation
- 1996-06-03 NZ NZ310644A patent/NZ310644A/xx unknown
- 1996-06-03 EP EP96919016A patent/EP0831787B1/en not_active Expired - Lifetime
- 1996-06-03 JP JP9500870A patent/JPH11506740A/ja active Pending
- 1996-06-03 AU AU61469/96A patent/AU708756B2/en not_active Ceased
- 1996-06-03 PT PT96919016T patent/PT831787E/pt unknown
- 1996-06-03 AT AT96919016T patent/ATE204468T1/de not_active IP Right Cessation
- 1996-06-03 BR BR9608542-8A patent/BR9608542A/pt not_active Application Discontinuation
- 1996-06-03 CA CA002223436A patent/CA2223436A1/en not_active Abandoned
- 1996-06-03 WO PCT/US1996/008086 patent/WO1996040072A2/en not_active Application Discontinuation
- 1996-06-03 CZ CZ19973907A patent/CZ288147B6/cs not_active IP Right Cessation
- 1996-06-03 IL IL12238596A patent/IL122385A/xx not_active IP Right Cessation
- 1996-06-03 CN CN96194614A patent/CN1102854C/zh not_active Expired - Fee Related
- 1996-06-03 DK DK96919016T patent/DK0831787T3/da active
- 1996-06-03 ES ES96919016T patent/ES2161366T3/es not_active Expired - Lifetime
- 1996-06-03 PL PL96323832A patent/PL184531B1/pl not_active IP Right Cessation
- 1996-06-03 SK SK1671-97A patent/SK281571B6/sk unknown
- 1996-06-03 HU HU9900870A patent/HUP9900870A3/hu unknown
- 1996-06-03 DE DE69614685T patent/DE69614685T2/de not_active Expired - Fee Related
-
1997
- 1997-12-05 MX MX9709698A patent/MX9709698A/es not_active IP Right Cessation
- 1997-12-05 NO NO19975708A patent/NO316104B1/no unknown
-
1998
- 1998-08-19 HK HK98110029A patent/HK1009089A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
SK167197A3 (en) | 1998-06-03 |
DE69614685T2 (de) | 2002-06-27 |
ES2161366T3 (es) | 2001-12-01 |
PT831787E (pt) | 2002-02-28 |
DE69614685D1 (de) | 2001-09-27 |
NO975708D0 (no) | 1997-12-05 |
NO316104B1 (no) | 2003-12-15 |
CZ390797A3 (cs) | 1998-07-15 |
HUP9900870A3 (en) | 2001-04-28 |
CN1102854C (zh) | 2003-03-12 |
MX9709698A (es) | 1998-07-31 |
DK0831787T3 (da) | 2001-12-17 |
BR9608542A (pt) | 1999-11-30 |
WO1996040072A3 (en) | 1997-01-23 |
HK1009089A1 (en) | 1999-09-10 |
HUP9900870A2 (hu) | 1999-09-28 |
RU2161502C2 (ru) | 2001-01-10 |
NO975708L (no) | 1998-02-05 |
CZ288147B6 (en) | 2001-05-16 |
AU6146996A (en) | 1996-12-30 |
CA2223436A1 (en) | 1996-12-19 |
ATE204468T1 (de) | 2001-09-15 |
IL122385A0 (en) | 1998-06-15 |
PL184531B1 (pl) | 2002-11-29 |
CN1187120A (zh) | 1998-07-08 |
NZ310644A (en) | 1999-08-30 |
WO1996040072A2 (en) | 1996-12-19 |
PL323832A1 (en) | 1998-04-27 |
EP0831787B1 (en) | 2001-08-22 |
JPH11506740A (ja) | 1999-06-15 |
SK281571B6 (sk) | 2001-05-10 |
EP0831787A2 (en) | 1998-04-01 |
AU708756B2 (en) | 1999-08-12 |
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