IL118485A - 5,6-dihydro-9H-pyrazolo¬3,4-c¾-1,2,4-triazolo¬4,3-a¾ pyridines and pharmaceutical compositions containing them - Google Patents

5,6-dihydro-9H-pyrazolo¬3,4-c¾-1,2,4-triazolo¬4,3-a¾ pyridines and pharmaceutical compositions containing them

Info

Publication number
IL118485A
IL118485A IL11848596A IL11848596A IL118485A IL 118485 A IL118485 A IL 118485A IL 11848596 A IL11848596 A IL 11848596A IL 11848596 A IL11848596 A IL 11848596A IL 118485 A IL118485 A IL 118485A
Authority
IL
Israel
Prior art keywords
triazolo
pyrazolo
pyridines
dihydro
pharmaceutical compositions
Prior art date
Application number
IL11848596A
Other languages
English (en)
Other versions
IL118485A0 (en
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of IL118485A0 publication Critical patent/IL118485A0/xx
Publication of IL118485A publication Critical patent/IL118485A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • AIDS & HIV (AREA)
  • Pain & Pain Management (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL11848596A 1995-06-06 1996-05-30 5,6-dihydro-9H-pyrazolo¬3,4-c¾-1,2,4-triazolo¬4,3-a¾ pyridines and pharmaceutical compositions containing them IL118485A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CA002223624A CA2223624C (en) 1995-06-06 1995-06-06 Tricyclic 5,6-dihydro-9h-pyrazolo[3,4-c]-1,2,4-triazolo[4,3-.alpha.]pyridines
PCT/IB1995/000429 WO1996039408A1 (en) 1995-06-06 1995-06-06 TRICYCLIC 5,6-DIHYDRO-9H-PYRAZOLO[3,4-c]-1,2,4-TRIAZOLO[4,3-α]PYRIDINES
HU9601541A HUP9601541A3 (en) 1995-06-06 1996-06-05 Tricyclic 5,6-dihydro-9h-pyrazolo[3,4-c]-1,2,4-triazolol[4,3-a]-pyridines and pharmaceutical compositions containing them

Publications (2)

Publication Number Publication Date
IL118485A0 IL118485A0 (en) 1996-09-12
IL118485A true IL118485A (en) 2000-02-17

Family

ID=89994031

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11848596A IL118485A (en) 1995-06-06 1996-05-30 5,6-dihydro-9H-pyrazolo¬3,4-c¾-1,2,4-triazolo¬4,3-a¾ pyridines and pharmaceutical compositions containing them

Country Status (43)

Country Link
US (1) US6004974A (ko)
EP (1) EP0837860B1 (ko)
JP (1) JP3107827B2 (ko)
KR (2) KR100191972B1 (ko)
CN (1) CN1061044C (ko)
AP (1) AP609A (ko)
AR (1) AR002745A1 (ko)
AT (1) ATE214700T1 (ko)
AU (1) AU694871B2 (ko)
BG (1) BG62568B1 (ko)
BR (1) BR9602627A (ko)
CA (1) CA2223624C (ko)
CO (1) CO4700460A1 (ko)
CZ (1) CZ287251B6 (ko)
DE (1) DE69525978T2 (ko)
DK (1) DK0837860T3 (ko)
DZ (1) DZ2044A1 (ko)
ES (1) ES2172583T3 (ko)
FI (1) FI114097B (ko)
HR (1) HRP960268B1 (ko)
HU (1) HUP9601541A3 (ko)
IL (1) IL118485A (ko)
IS (1) IS1913B (ko)
LV (1) LV11620B (ko)
MA (1) MA23893A1 (ko)
MX (1) MX9709897A (ko)
MY (1) MY116527A (ko)
NO (1) NO306256B1 (ko)
NZ (1) NZ286734A (ko)
OA (1) OA10458A (ko)
PL (1) PL184195B1 (ko)
PT (1) PT837860E (ko)
RO (1) RO115881B1 (ko)
RU (1) RU2161158C2 (ko)
SA (1) SA96170065B1 (ko)
SG (1) SG54341A1 (ko)
SI (1) SI9600186A (ko)
SK (1) SK282167B6 (ko)
TN (1) TNSN96083A1 (ko)
TR (1) TR199600482A1 (ko)
TW (1) TW460469B (ko)
WO (1) WO1996039408A1 (ko)
YU (1) YU49346B (ko)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2792938B1 (fr) 1999-04-28 2001-07-06 Warner Lambert Co NOUVELLES 1-AMINO TRIAZOLO [4,3-a] QUINAZOLINE-5-ONES INHIBITRICES DE PHOSPHODIESTERASES IV
US6326495B2 (en) * 1999-04-30 2001-12-04 Pfizer Inc. Process for preparing 8-cyclopentyl-6-ethyl-3-[substituted]-5,8-dihydro-4H-1,2,3a,7,8-pentaaza-as-indacenes and intermediates useful therein
EP1380585B1 (en) * 1999-04-30 2004-11-10 Pfizer Products Inc. Pyrazolopyridinone as intermediate
CA2381802C (en) 1999-08-21 2010-12-07 Byk Gulden Lomberg Chemische Fabrik Gmbh Synergistic combination of roflumilast and salmeterol
WO2001068600A2 (en) * 2000-03-16 2001-09-20 Inflazyme Pharmaceuticals Limited Benzylated pde4 inhibitors
MXPA03010791A (es) * 2001-05-25 2004-03-02 Boehringer Ingelheim Pharma Combinacion de inhibidor de pde4 y tiotropio a sus derivados para tratamiento de enfermedades obstructivas de vias respiratorias y de otras enfermedades inflamatorias.
JP2005508861A (ja) * 2001-05-25 2005-04-07 ファイザー・インク 閉塞性気管疾患の治療のためのｐｄｅ４阻害剤及び抗コリン性剤の組み合わせ物
GB0122031D0 (en) * 2001-09-12 2001-10-31 Pfizer Ltd Use of pde4 inhibitors in a dry powder inhaler
GB0129395D0 (en) * 2001-12-07 2002-01-30 Pfizer Ltd Pharmaceutical combination
US20050107420A1 (en) * 2002-05-23 2005-05-19 Boehringe Ingelheim Pharma Gmbh & Co. Kg Combination of a PDE4 inhibitor and tiotropium or derivative thereof for treating obstructive airways and other inflammatory diseases
WO2006075748A1 (ja) * 2005-01-17 2006-07-20 Santen Pharmaceutical Co., Ltd. アレルギー性結膜疾患治療剤
RU2008119323A (ru) 2005-10-19 2009-11-27 Рэнбакси Лабораториз Лимитед (In) Фармацевтические композиции мускаринового рецептора
CN102764440A (zh) 2006-07-05 2012-11-07 奈科明有限责任公司 用于治疗炎症性肺部疾病的HMG-CoA还原酶抑制剂与磷酸二酯酶4抑制剂的组合
US8653097B2 (en) * 2008-10-17 2014-02-18 Boehringer Ingelheim International Gmbh Tetra-aza-heterocycles as phosphatidylinositol-3-kinases (P13-kinases) inhibitor
JP5730896B2 (ja) * 2009-12-04 2015-06-10 ネルビアーノ・メデイカル・サイエンシーズ・エツセ・エルレ・エルレ トリシクロピラゾール誘導体
WO2013084182A1 (en) 2011-12-08 2013-06-13 Glenmark Pharmaceuticals S.A. Pharmaceutical composition that includes a pde4 enzyme inhibitor and an analgesic agent

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3697532A (en) * 1970-08-12 1972-10-10 Squibb & Sons Inc 5-methyldipyrazolo {8 3,4-b;3{40 ,4{40 -d{9 {0 pyridin-3(2h)-ones
HUT74170A (en) * 1993-07-06 1996-11-28 Pfizer Bicyclic tetrahydro pyrazolopyridines
CA2143143A1 (en) * 1994-03-08 1995-09-09 Toshihiko Tanaka 3-phenylpyrrolidine derivatives

Also Published As

Publication number Publication date
FI974434A (fi) 1997-12-05
YU34696A (sh) 1999-07-28
CN1142499A (zh) 1997-02-12
JP3107827B2 (ja) 2000-11-13
TNSN96083A1 (fr) 2005-03-15
CO4700460A1 (es) 1998-12-29
NZ286734A (en) 1998-02-26
RU2161158C2 (ru) 2000-12-27
PT837860E (pt) 2002-07-31
SA96170065B1 (ar) 2005-12-21
NO306256B1 (no) 1999-10-11
HU9601541D0 (en) 1996-07-29
MX9709897A (es) 1998-03-31
CA2223624C (en) 2001-02-20
BR9602627A (pt) 1998-09-01
CN1061044C (zh) 2001-01-24
EP0837860B1 (en) 2002-03-20
BG62568B1 (bg) 2000-02-29
MY116527A (en) 2004-02-28
KR970003440A (ko) 1997-01-28
DZ2044A1 (fr) 2002-07-21
IL118485A0 (en) 1996-09-12
PL184195B1 (pl) 2002-09-30
CA2223624A1 (en) 1996-12-12
PL314459A1 (en) 1996-12-09
KR100191972B1 (ko) 1999-06-15
FI974434A0 (fi) 1997-12-05
JPH10510242A (ja) 1998-10-06
IS1913B (is) 2004-02-03
EP0837860A1 (en) 1998-04-29
HRP960268B1 (en) 2002-12-31
IS4350A (is) 1996-12-07
OA10458A (en) 2002-03-27
DK0837860T3 (da) 2002-05-27
SK282167B6 (sk) 2001-11-06
AU5477396A (en) 1996-12-19
HUP9601541A3 (en) 1997-05-28
KR100225719B1 (en) 1999-10-15
HUP9601541A2 (en) 1997-02-28
DE69525978D1 (de) 2002-04-25
LV11620B (en) 1997-04-20
ATE214700T1 (de) 2002-04-15
RO115881B1 (ro) 2000-07-28
NO962320L (no) 1996-12-09
ES2172583T3 (es) 2002-10-01
YU49346B (sh) 2005-07-19
LV11620A (lv) 1996-12-20
AU694871B2 (en) 1998-07-30
HRP960268A2 (en) 1997-08-31
AR002745A1 (es) 1998-04-29
WO1996039408A1 (en) 1996-12-12
CZ162696A3 (en) 1997-01-15
US6004974A (en) 1999-12-21
TR199600482A1 (tr) 1997-03-21
SI9600186A (en) 1997-04-30
SK71896A3 (en) 1997-05-07
DE69525978T2 (de) 2002-12-19
SG54341A1 (en) 1998-11-16
MA23893A1 (fr) 1996-12-31
NO962320D0 (no) 1996-06-05
FI114097B (fi) 2004-08-13
AP609A (en) 1997-09-03
AP9600806A0 (en) 1996-07-31
CZ287251B6 (en) 2000-10-11
TW460469B (en) 2001-10-21
BG100640A (bg) 1997-03-31

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Legal Events

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KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees