HUP9601541A3 - Tricyclic 5,6-dihydro-9h-pyrazolo[3,4-c]-1,2,4-triazolol[4,3-a]-pyridines and pharmaceutical compositions containing them - Google Patents

Tricyclic 5,6-dihydro-9h-pyrazolo[3,4-c]-1,2,4-triazolol[4,3-a]-pyridines and pharmaceutical compositions containing them

Info

Publication number
HUP9601541A3
HUP9601541A3 HU9601541A HUP9601541A HUP9601541A3 HU P9601541 A3 HUP9601541 A3 HU P9601541A3 HU 9601541 A HU9601541 A HU 9601541A HU P9601541 A HUP9601541 A HU P9601541A HU P9601541 A3 HUP9601541 A3 HU P9601541A3
Authority
HU
Hungary
Prior art keywords
triazolol
pyrazolo
pyridines
tricyclic
dihydro
Prior art date
Application number
HU9601541A
Other languages
English (en)
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to DE69525978T priority Critical patent/DE69525978T2/de
Priority to US08/973,590 priority patent/US6004974A/en
Priority to AT95918707T priority patent/ATE214700T1/de
Priority to PCT/IB1995/000429 priority patent/WO1996039408A1/en
Priority to ES95918707T priority patent/ES2172583T3/es
Priority to JP08511176A priority patent/JP3107827B2/ja
Priority to CA002223624A priority patent/CA2223624C/en
Priority to PT95918707T priority patent/PT837860E/pt
Priority to DK95918707T priority patent/DK0837860T3/da
Priority to EP95918707A priority patent/EP0837860B1/en
Priority to MX9709897A priority patent/MX9709897A/es
Priority to SK718-96A priority patent/SK282167B6/sk
Priority to TW085105271A priority patent/TW460469B/zh
Priority to APAP/P/1996/000806A priority patent/AP609A/en
Priority to ARP960102626A priority patent/AR002745A1/es
Priority to PL96314459A priority patent/PL184195B1/pl
Priority to IL11848596A priority patent/IL118485A/xx
Priority to IS4350A priority patent/IS1913B/is
Priority to SA96170065A priority patent/SA96170065B1/ar
Priority to BR9602627A priority patent/BR9602627A/pt
Priority to LVP-96-174A priority patent/LV11620B/en
Priority to DZ960088A priority patent/DZ2044A1/fr
Priority to NO962320A priority patent/NO306256B1/no
Priority to KR1019960020169A priority patent/KR100191972B1/ko
Application filed by Pfizer filed Critical Pfizer
Priority to MYPI96002201A priority patent/MY116527A/en
Priority to BG100640A priority patent/BG62568B1/bg
Priority to RU96111027/04A priority patent/RU2161158C2/ru
Priority to NZ286734A priority patent/NZ286734A/en
Priority to MA24263A priority patent/MA23893A1/fr
Priority to TNTNSN96083A priority patent/TNSN96083A1/fr
Priority to SG1996009983A priority patent/SG54341A1/en
Priority to HU9601541A priority patent/HUP9601541A3/hu
Priority to AU54773/96A priority patent/AU694871B2/en
Priority to YU34696A priority patent/YU49346B/sh
Priority to CZ19961626A priority patent/CZ287251B6/cs
Priority to CN96107630A priority patent/CN1061044C/zh
Priority to TR96/00482A priority patent/TR199600482A1/xx
Priority to HR960268A priority patent/HRP960268B1/xx
Priority to OA60834A priority patent/OA10458A/en
Priority to RO96-01157A priority patent/RO115881B1/ro
Priority to CO96029521A priority patent/CO4700460A1/es
Priority to SI9600186A priority patent/SI9600186A/sl
Publication of HU9601541D0 publication Critical patent/HU9601541D0/hu
Publication of HUP9601541A2 publication Critical patent/HUP9601541A2/hu
Publication of HUP9601541A3 publication Critical patent/HUP9601541A3/hu
Priority to FI974434A priority patent/FI114097B/fi
Priority to KR1019980044720A priority patent/KR100225719B1/ko

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • AIDS & HIV (AREA)
  • Pain & Pain Management (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HU9601541A 1995-06-06 1996-06-05 Tricyclic 5,6-dihydro-9h-pyrazolo[3,4-c]-1,2,4-triazolol[4,3-a]-pyridines and pharmaceutical compositions containing them HUP9601541A3 (en)

Priority Applications (44)

Application Number Priority Date Filing Date Title
SK718-96A SK282167B6 (sk) 1995-06-06 1995-06-06 Tricyklické 5,6-dihydro-9h-pyrazolo[3,4-c]-1,2,4-triazolo[4,3-a] pyridíny a farmaceutický prostriedok na ich báze
MX9709897A MX9709897A (es) 1995-06-06 1995-06-06 5-6-dihidro-9h-pirazol[3,4-c]-1,2,4-triazol[4,3-a]piridinas triciclicas y el uso de las mismas.
AT95918707T ATE214700T1 (de) 1995-06-06 1995-06-06 Trizyclische 5,6-dihydro-9h-pyrazolo(3,4-c)-1,2,4-triazolo(4 3-alpha)pyridine
US08/973,590 US6004974A (en) 1995-06-06 1995-06-06 Tricyclic 5,6-dihydro-9h-pyrazolo[3,4-c]-1,2,4-triazolo[4,3-α]pyridines
JP08511176A JP3107827B2 (ja) 1995-06-06 1995-06-06 トリサイクリック５，６−ジヒドロ−９Ｈ−ピラゾロ［３，４−ｃ］−１，２，４−トリアゾロ［４，３−ａ］ピリジン類
CA002223624A CA2223624C (en) 1995-06-06 1995-06-06 Tricyclic 5,6-dihydro-9h-pyrazolo[3,4-c]-1,2,4-triazolo[4,3-.alpha.]pyridines
PT95918707T PT837860E (pt) 1995-06-06 1995-06-06 5,6-di-hidro-9h-pirazolo¬3,4-c|-1,2,4-triazolo¬4,3-alfa|piridinas triciclicas
DK95918707T DK0837860T3 (da) 1995-06-06 1995-06-06 Tricykliske 5,6-dihydro-9H-pyrazolo[3,4-c]-1,2,4-triazolo-[4,3-alfa]pyridiner
EP95918707A EP0837860B1 (en) 1995-06-06 1995-06-06 TRICYCLIC 5,6-DIHYDRO-9H-PYRAZOLO(3,4-c]-1,2,4-TRIAZOLO(4,3-ALPHA]PYRIDINES
DE69525978T DE69525978T2 (de) 1995-06-06 1995-06-06 Trizyclische 5,6-dihydro-9h-pyrazolo(3,4-c)-1,2,4-triazolo(4,3-alpha)pyridine
ES95918707T ES2172583T3 (es) 1995-06-06 1995-06-06 5,6-dihidro-9h-pirazol(3,4-c)-1,2,4-triazol(4,3-alfa)piridinas triciclicas.
PCT/IB1995/000429 WO1996039408A1 (en) 1995-06-06 1995-06-06 TRICYCLIC 5,6-DIHYDRO-9H-PYRAZOLO[3,4-c]-1,2,4-TRIAZOLO[4,3-α]PYRIDINES
TW085105271A TW460469B (en) 1995-06-06 1996-05-02 Tricyclic 5,6-dihydro-9H-pyrazolo[3,4-c]-1,2,4-triazolo[4,3-a]pyridines
APAP/P/1996/000806A AP609A (en) 1995-06-06 1996-05-06 Tricyclic 5,6-dihydro-9H-pyrazolo[3,4c]-1,2,4-triazolo[4,3-A]pyridines.
ARP960102626A AR002745A1 (es) 1995-06-06 1996-05-20 5,6-DIHIDRO-9H-PIRAZOL[3,4-c]-1,2,4-TRIAZOL [4,3-a] PIRIDINAS TRICICLICAS Y COMPOSICIONES FARMACEUTICAS CONTENIENDO LAS MISMAS.
PL96314459A PL184195B1 (pl) 1995-06-06 1996-05-27 Nowe 5,6-dihydro-9H-pirazolo [3,4-c]-1,2,4-triazolo [4,3-a] pirydyny i środek farmaceutyczny
IL11848596A IL118485A (en) 1995-06-06 1996-05-30 5,6-dihydro-9H-pyrazolo¬3,4-c¾-1,2,4-triazolo¬4,3-a¾ pyridines and pharmaceutical compositions containing them
IS4350A IS1913B (is) 1995-06-06 1996-06-03 Trísýklísk 5,6-díhýdró-9H-pýrazóló[3,4c]-1,2,4-tríazóló[4,3a]pýridín, notkun þeirra og lyfjablanda
BR9602627A BR9602627A (pt) 1995-06-06 1996-06-04 Composto método para inibição de fosfodiestirase (pde) tipo iv método de tratamento ou prevenção de uma condição e composição farmacéutica
LVP-96-174A LV11620B (en) 1995-06-06 1996-06-04 Tricyclic 5,6-dihydro-9h-pyrazolo£3,4-c|-1,2,4-triazolo£4,3-a|pyridines
SA96170065A SA96170065B1 (ar) 1995-06-06 1996-06-04 مركب TRICYCLIC 5,6-DIHYDRO-9H-PYRAZOLO[4,3-a]PYRIDI-NES
YU34696A YU49346B (sh) 1995-06-06 1996-06-05 TRICIKLICNI 5,6-DIHIDRO-9H-PIRAZOLO [3,4-c] -1,2,4-TRIAZOLO [4,3-α] PIRIDINI
KR1019960020169A KR100191972B1 (ko) 1995-06-06 1996-06-05 삼환5,6-디하이드로-9h-피라졸로[3,4-c]-1,2,4-트리아졸로[4,3-a]피리딘
DZ960088A DZ2044A1 (fr) 1995-06-06 1996-06-05 5,6-Dihydro-9h-pyrazolo Ä3,4-cÜ-1,2,4-triazol Ä4,3-alphaÜpyridines tricycliques procédé pour leur préparation et compositions les contenant.
MYPI96002201A MY116527A (en) 1995-06-06 1996-06-05 Tricyclic 5, 6-dihydro-9h-pyrazolo [3,4,-c]-1,2,4- triazolo [4,3-a] pyridines
BG100640A BG62568B1 (bg) 1995-06-06 1996-06-05 Трициклени5,6-дихидро-9н-пиразоло[3,4-c]-1,2,4-триазоло[4,3-a] пиридини
RU96111027/04A RU2161158C2 (ru) 1995-06-06 1996-06-05 Трициклические 5,6-дигидро-9h-пиразоло[3,4-с]-1,2,4-триазоло [4,3-а] пиридины, способ ингибирования фосфодиэстеразы типа iу и способ ингибирования продуцирования фактора опухолеспецифического некроза
NZ286734A NZ286734A (en) 1995-06-06 1996-06-05 Pyrazolo[3,4-c]-1,2,4-triazolo[4,3-a]pyridines and medicaments
MA24263A MA23893A1 (fr) 1995-06-06 1996-06-05 5,6 - dihydro-9h -pyrazolo (3, 4-c) - 1,2,4- triazolo (4, 3-x) pyridines tricycliques , procede pour leur preparation et compositions les contenant
TNTNSN96083A TNSN96083A1 (fr) 1995-06-06 1996-06-05 5, 6-DIHYDRO-9H-PYRAZOLO (3,4-C) -1, 2, 4-TRIAZOLO ( 4,3-α ) PYRIDINES TRICYCLIQUES, PROCEDE POUR LEUR PREPARATION ET COMPOSITIONS LES CONTENANT
SG1996009983A SG54341A1 (en) 1995-06-06 1996-06-05 Tricyclic 5,6-dihydro-9h-pyrazola[3,4-c] 1,2,4-triazolo[4,3-alpha] pyridines
HU9601541A HUP9601541A3 (en) 1995-06-06 1996-06-05 Tricyclic 5,6-dihydro-9h-pyrazolo[3,4-c]-1,2,4-triazolol[4,3-a]-pyridines and pharmaceutical compositions containing them
AU54773/96A AU694871B2 (en) 1995-06-06 1996-06-05 Tricyclic 5,6-dihydro-9H-pyrazolo(3,4-c)1,2,4-triazolo (4,3-a)pyridines
NO962320A NO306256B1 (no) 1995-06-06 1996-06-05 Tricykliske 5,6-dihydro-9H-pyrazolo [3,4c]-1,2,4-triazolo [4,3-a]pyridiner, anvendelse derav og farmasöytisk preparat
CZ19961626A CZ287251B6 (en) 1995-06-06 1996-06-05 Tricyclic 5,6-dihydro-9H-pyrazolo[3,4-c]-1,2,4-triazolo[4,3-a]pyridines and pharmaceutical preparation based thereon
CN96107630A CN1061044C (zh) 1995-06-06 1996-06-06 三环5,6－二氢－9H－吡唑并[3,4－C]－1,2,4－***并[4,3－α]吡啶
TR96/00482A TR199600482A1 (tr) 1995-06-06 1996-06-06 Trisiklik 5,6-dihidro-9H-pirazolo(3,4-c)-1,2,4-triazolo (4,3-a) piridinler.
HR960268A HRP960268B1 (en) 1995-06-06 1996-06-06 TRICYCLIC 5,6-DIHYDRO-9H-PYRAZOLO/3,4-c/-1,2,4-TRIAZOLO/4,3-ALPHA/PYRIDINES
OA60834A OA10458A (en) 1995-06-06 1996-06-06 Tricyclic 5,6-dihydro-9h-pyrazolo Ä3,4-cÜ-1,2,4-triazolo Ä4,3-alphaÜpyridines
RO96-01157A RO115881B1 (ro) 1995-06-06 1996-06-06 Derivati de triazol [4,3-alfa]piridine, compozitie farmaceutica si metoda de tratament
CO96029521A CO4700460A1 (es) 1995-06-06 1996-06-06 5,6-DIHIDRO-9H-PIRAZOL[3,4-c]-1,2,4-TRIAZOL[4,3-a] PIRIDINAS TRICICLICAS
SI9600186A SI9600186A (en) 1995-06-06 1996-06-06 Tricyclic 5,6-dihydro-9h-pyrazolo (3,4-c)-1,2,4-triazolo (4,3-alpha) pyridines
FI974434A FI114097B (fi) 1995-06-06 1997-12-05 Trisyklisiä 5,6-dihydro-9H-pyratsolo[3,4-c]-1,2,4-triatsolo[4,3-alfa]pyridiinejä
KR1019980044720A KR100225719B1 (en) 1995-06-06 1998-10-24 Pharmaceutical compositions containing tricyclic 5,6-dihydro-9h-pyrazolo[3,4-c]-1,2,4-triazolo-[4,3-alpha]pyridines

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CA002223624A CA2223624C (en) 1995-06-06 1995-06-06 Tricyclic 5,6-dihydro-9h-pyrazolo[3,4-c]-1,2,4-triazolo[4,3-.alpha.]pyridines
PCT/IB1995/000429 WO1996039408A1 (en) 1995-06-06 1995-06-06 TRICYCLIC 5,6-DIHYDRO-9H-PYRAZOLO[3,4-c]-1,2,4-TRIAZOLO[4,3-α]PYRIDINES
HU9601541A HUP9601541A3 (en) 1995-06-06 1996-06-05 Tricyclic 5,6-dihydro-9h-pyrazolo[3,4-c]-1,2,4-triazolol[4,3-a]-pyridines and pharmaceutical compositions containing them

Publications (3)

Publication Number Publication Date
HU9601541D0 HU9601541D0 (en) 1996-07-29
HUP9601541A2 HUP9601541A2 (en) 1997-02-28
HUP9601541A3 true HUP9601541A3 (en) 1997-05-28

Family

ID=89994031

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9601541A HUP9601541A3 (en) 1995-06-06 1996-06-05 Tricyclic 5,6-dihydro-9h-pyrazolo[3,4-c]-1,2,4-triazolol[4,3-a]-pyridines and pharmaceutical compositions containing them

Country Status (43)

Country Link
US (1) US6004974A (hu)
EP (1) EP0837860B1 (hu)
JP (1) JP3107827B2 (hu)
KR (2) KR100191972B1 (hu)
CN (1) CN1061044C (hu)
AP (1) AP609A (hu)
AR (1) AR002745A1 (hu)
AT (1) ATE214700T1 (hu)
AU (1) AU694871B2 (hu)
BG (1) BG62568B1 (hu)
BR (1) BR9602627A (hu)
CA (1) CA2223624C (hu)
CO (1) CO4700460A1 (hu)
CZ (1) CZ287251B6 (hu)
DE (1) DE69525978T2 (hu)
DK (1) DK0837860T3 (hu)
DZ (1) DZ2044A1 (hu)
ES (1) ES2172583T3 (hu)
FI (1) FI114097B (hu)
HR (1) HRP960268B1 (hu)
HU (1) HUP9601541A3 (hu)
IL (1) IL118485A (hu)
IS (1) IS1913B (hu)
LV (1) LV11620B (hu)
MA (1) MA23893A1 (hu)
MX (1) MX9709897A (hu)
MY (1) MY116527A (hu)
NO (1) NO306256B1 (hu)
NZ (1) NZ286734A (hu)
OA (1) OA10458A (hu)
PL (1) PL184195B1 (hu)
PT (1) PT837860E (hu)
RO (1) RO115881B1 (hu)
RU (1) RU2161158C2 (hu)
SA (1) SA96170065B1 (hu)
SG (1) SG54341A1 (hu)
SI (1) SI9600186A (hu)
SK (1) SK282167B6 (hu)
TN (1) TNSN96083A1 (hu)
TR (1) TR199600482A1 (hu)
TW (1) TW460469B (hu)
WO (1) WO1996039408A1 (hu)
YU (1) YU49346B (hu)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2792938B1 (fr) 1999-04-28 2001-07-06 Warner Lambert Co NOUVELLES 1-AMINO TRIAZOLO [4,3-a] QUINAZOLINE-5-ONES INHIBITRICES DE PHOSPHODIESTERASES IV
US6326495B2 (en) * 1999-04-30 2001-12-04 Pfizer Inc. Process for preparing 8-cyclopentyl-6-ethyl-3-[substituted]-5,8-dihydro-4H-1,2,3a,7,8-pentaaza-as-indacenes and intermediates useful therein
EP1380585B1 (en) * 1999-04-30 2004-11-10 Pfizer Products Inc. Pyrazolopyridinone as intermediate
CA2381802C (en) 1999-08-21 2010-12-07 Byk Gulden Lomberg Chemische Fabrik Gmbh Synergistic combination of roflumilast and salmeterol
WO2001068600A2 (en) * 2000-03-16 2001-09-20 Inflazyme Pharmaceuticals Limited Benzylated pde4 inhibitors
MXPA03010791A (es) * 2001-05-25 2004-03-02 Boehringer Ingelheim Pharma Combinacion de inhibidor de pde4 y tiotropio a sus derivados para tratamiento de enfermedades obstructivas de vias respiratorias y de otras enfermedades inflamatorias.
JP2005508861A (ja) * 2001-05-25 2005-04-07 ファイザー・インク 閉塞性気管疾患の治療のためのｐｄｅ４阻害剤及び抗コリン性剤の組み合わせ物
GB0122031D0 (en) * 2001-09-12 2001-10-31 Pfizer Ltd Use of pde4 inhibitors in a dry powder inhaler
GB0129395D0 (en) * 2001-12-07 2002-01-30 Pfizer Ltd Pharmaceutical combination
US20050107420A1 (en) * 2002-05-23 2005-05-19 Boehringe Ingelheim Pharma Gmbh & Co. Kg Combination of a PDE4 inhibitor and tiotropium or derivative thereof for treating obstructive airways and other inflammatory diseases
WO2006075748A1 (ja) * 2005-01-17 2006-07-20 Santen Pharmaceutical Co., Ltd. アレルギー性結膜疾患治療剤
RU2008119323A (ru) 2005-10-19 2009-11-27 Рэнбакси Лабораториз Лимитед (In) Фармацевтические композиции мускаринового рецептора
CN102764440A (zh) 2006-07-05 2012-11-07 奈科明有限责任公司 用于治疗炎症性肺部疾病的HMG-CoA还原酶抑制剂与磷酸二酯酶4抑制剂的组合
US8653097B2 (en) * 2008-10-17 2014-02-18 Boehringer Ingelheim International Gmbh Tetra-aza-heterocycles as phosphatidylinositol-3-kinases (P13-kinases) inhibitor
JP5730896B2 (ja) * 2009-12-04 2015-06-10 ネルビアーノ・メデイカル・サイエンシーズ・エツセ・エルレ・エルレ トリシクロピラゾール誘導体
WO2013084182A1 (en) 2011-12-08 2013-06-13 Glenmark Pharmaceuticals S.A. Pharmaceutical composition that includes a pde4 enzyme inhibitor and an analgesic agent

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3697532A (en) * 1970-08-12 1972-10-10 Squibb & Sons Inc 5-methyldipyrazolo {8 3,4-b;3{40 ,4{40 -d{9 {0 pyridin-3(2h)-ones
HUT74170A (en) * 1993-07-06 1996-11-28 Pfizer Bicyclic tetrahydro pyrazolopyridines
CA2143143A1 (en) * 1994-03-08 1995-09-09 Toshihiko Tanaka 3-phenylpyrrolidine derivatives

Also Published As

Publication number Publication date
FI974434A (fi) 1997-12-05
YU34696A (sh) 1999-07-28
CN1142499A (zh) 1997-02-12
JP3107827B2 (ja) 2000-11-13
TNSN96083A1 (fr) 2005-03-15
CO4700460A1 (es) 1998-12-29
NZ286734A (en) 1998-02-26
RU2161158C2 (ru) 2000-12-27
PT837860E (pt) 2002-07-31
SA96170065B1 (ar) 2005-12-21
NO306256B1 (no) 1999-10-11
HU9601541D0 (en) 1996-07-29
MX9709897A (es) 1998-03-31
CA2223624C (en) 2001-02-20
BR9602627A (pt) 1998-09-01
CN1061044C (zh) 2001-01-24
EP0837860B1 (en) 2002-03-20
BG62568B1 (bg) 2000-02-29
MY116527A (en) 2004-02-28
KR970003440A (ko) 1997-01-28
DZ2044A1 (fr) 2002-07-21
IL118485A0 (en) 1996-09-12
PL184195B1 (pl) 2002-09-30
CA2223624A1 (en) 1996-12-12
PL314459A1 (en) 1996-12-09
KR100191972B1 (ko) 1999-06-15
FI974434A0 (fi) 1997-12-05
JPH10510242A (ja) 1998-10-06
IS1913B (is) 2004-02-03
EP0837860A1 (en) 1998-04-29
HRP960268B1 (en) 2002-12-31
IS4350A (is) 1996-12-07
OA10458A (en) 2002-03-27
DK0837860T3 (da) 2002-05-27
SK282167B6 (sk) 2001-11-06
AU5477396A (en) 1996-12-19
KR100225719B1 (en) 1999-10-15
HUP9601541A2 (en) 1997-02-28
DE69525978D1 (de) 2002-04-25
LV11620B (en) 1997-04-20
ATE214700T1 (de) 2002-04-15
RO115881B1 (ro) 2000-07-28
NO962320L (no) 1996-12-09
ES2172583T3 (es) 2002-10-01
YU49346B (sh) 2005-07-19
LV11620A (lv) 1996-12-20
AU694871B2 (en) 1998-07-30
HRP960268A2 (en) 1997-08-31
AR002745A1 (es) 1998-04-29
WO1996039408A1 (en) 1996-12-12
CZ162696A3 (en) 1997-01-15
US6004974A (en) 1999-12-21
TR199600482A1 (tr) 1997-03-21
SI9600186A (en) 1997-04-30
SK71896A3 (en) 1997-05-07
DE69525978T2 (de) 2002-12-19
SG54341A1 (en) 1998-11-16
MA23893A1 (fr) 1996-12-31
NO962320D0 (no) 1996-06-05
FI114097B (fi) 2004-08-13
AP609A (en) 1997-09-03
AP9600806A0 (en) 1996-07-31
IL118485A (en) 2000-02-17
CZ287251B6 (en) 2000-10-11
TW460469B (en) 2001-10-21
BG100640A (bg) 1997-03-31

Similar Documents

Publication Publication Date Title
IL117621A (en) Tricyclic pyrido (3,2-e) pyrazinones their preparation and pharmaceutical compositions containing them
IL116774A (en) Tricyclic pyrrolobenzo diazepines and similar compounds their preparation and pharmaceutical compositions containing them
IL116775A (en) Tricyclic azolobenzodiazepines and similar compounds their preparation and pharmaceutical compositions containing them
HU9402076D0 (en) Pyrido[2,3-a]-pyridazin-5-one and pyrido[2,3a]-pyridiazin-5-thione derivatives, process for thein preparation and compositions containing them
GB9205051D0 (en) Pyrrolobenzodiazepine derivatives,their preparation,and compositions containing them
HUP9601541A3 (en) Tricyclic 5,6-dihydro-9h-pyrazolo[3,4-c]-1,2,4-triazolol[4,3-a]-pyridines and pharmaceutical compositions containing them
SI1001955T1 (en) 1,2,4-triazolo 4,3-b)pyrido 3,2-d)pyridazine derivatives and pharmaceutical compositions containing them
IL110175A (en) Tetrahydro pyrazolo (3,4-c)pyridine and the corresponding 7-one derivatives and pharmaceutical compositions containing them
NZ302881A (en) Tricyclic benzazepine (vaspressin antagonist) derivatives and medicaments containing them
IL116773A (en) Tricyclic benzazepine compounds their preparation and pharmaceutical compositions containing them
HUP9801394A3 (en) 6-phenyl-pyrazolo[3,4-d]pyrimidin-4-one derivatives and pharmaceutical compositions containing them
IL92791A0 (en) Annelated indolo(3,2-c)lactams,their preparation and pharmaceutical compositions containing them
IL106761A0 (en) 4,5-dihydro-4-oxo-pyrrolo(1,2-a)quinoxalinones and corresponding aza analogs,their preparation and pharmaceutical compositions containing them
IL103502A0 (en) Benzodiazepine derivatives,their preparation and pharmaceutical compositions containing them
HU9502726D0 (en) [1,2,4]triazolo[4,3-a]qunoxaline derivatives, their preparation and use
IL120590A0 (en) Pyrimido [1,2-a] indoles their preparation and pharmaceutical compositions containing them
IL90046A0 (en) 6-aryl-substituted-4h-thieno(2,3-e)(1,2,4)triazolo-(3,4-c)(1,4)diazepines,their preparation and pharmaceutical compositions containing them
HU9500386D0 (en) Benzodiazepine derivatives and pharmaceutical compositions containing them
HUP0003394A3 (en) Pyrido[2,3-b][1,5]benzodiazepine derivatives, their use, process for their preparation and pharmaceutical compositions containing them
IL105977A0 (en) Benzodiazepines,their preparation and pharmaceutical compositions containing them
IL110782A0 (en) Benzodiazepine derivatives, their preparation and pharmaceutical compositions containing them
IL117759A0 (en) 5H, 10H-imidazo [1, 2-a] indeno [1,2-e] pyrazin-4-one derivatives, their preparation and medications containing them
IL95638A0 (en) Tetrahydroimidazo(1,4)benzodiazepines,their preparation and pharmaceutical compositions containing them
IL104841A0 (en) Sulphonylbenzyl-substituted imidazopyridines,their preparation and pharmaceutical compositions containing them
IL115095A0 (en) Thiazolo (2,3-a) quinoline and - naphythyridine derivatives their preparation and pharmaceutical compositions containing them

Legal Events

Date Code Title Description
FA9A Lapse of provisional patent protection due to relinquishment or protection considered relinquished