IL118096A0 - Antibodies against interferon alpha/beta receptor - Google Patents

Antibodies against interferon alpha/beta receptor

Info

Publication number
IL118096A0
IL118096A0 IL11809696A IL11809696A IL118096A0 IL 118096 A0 IL118096 A0 IL 118096A0 IL 11809696 A IL11809696 A IL 11809696A IL 11809696 A IL11809696 A IL 11809696A IL 118096 A0 IL118096 A0 IL 118096A0
Authority
IL
Israel
Prior art keywords
antibodies against
interferon alpha
beta receptor
against interferon
receptor
Prior art date
Application number
IL11809696A
Other languages
English (en)
Original Assignee
Yeda Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yeda Res & Dev filed Critical Yeda Res & Dev
Priority to IL11809696A priority Critical patent/IL118096A0/xx
Publication of IL118096A0 publication Critical patent/IL118096A0/xx
Priority to KR1020047011388A priority patent/KR100581798B1/ko
Priority to DE69736835T priority patent/DE69736835T2/de
Priority to UA98116315A priority patent/UA76396C2/uk
Priority to BR9709202A priority patent/BR9709202A/pt
Priority to JP53837897A priority patent/JP4308322B2/ja
Priority to CA2253239A priority patent/CA2253239C/en
Priority to ES97919622T priority patent/ES2274542T3/es
Priority to CNB971951861A priority patent/CN1198929C/zh
Priority to EP06014510A priority patent/EP1739177A1/en
Priority to PT97919622T priority patent/PT927252E/pt
Priority to DK97919622T priority patent/DK0927252T3/da
Priority to EA199800968A priority patent/EA002543B1/ru
Priority to KR1019980708393A priority patent/KR20000064953A/ko
Priority to IL126835A priority patent/IL126835A/en
Priority to AT97919622T priority patent/ATE342981T1/de
Priority to SI9730754T priority patent/SI0927252T1/sl
Priority to PCT/IL1997/000138 priority patent/WO1997041229A1/en
Priority to AU24027/97A priority patent/AU719995B2/en
Priority to EP97919622A priority patent/EP0927252B1/en
Priority to US09/171,979 priority patent/US6136309A/en
Priority to NO19985050A priority patent/NO324206B1/no
Priority to HK99104252A priority patent/HK1019339A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10Cells modified by introduction of foreign genetic material
    • C12N5/12Fused cells, e.g. hybridomas
    • C12N5/16Animal cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/577Immunoassay; Biospecific binding assay; Materials therefor involving monoclonal antibodies binding reaction mechanisms characterised by the use of monoclonal antibodies; monoclonal antibodies per se are classified with their corresponding antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Obesity (AREA)
  • Mycology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Plant Pathology (AREA)
  • Diabetes (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Epidemiology (AREA)
IL11809696A 1996-05-01 1996-05-01 Antibodies against interferon alpha/beta receptor IL118096A0 (en)

Priority Applications (23)

Application Number Priority Date Filing Date Title
IL11809696A IL118096A0 (en) 1996-05-01 1996-05-01 Antibodies against interferon alpha/beta receptor
EP97919622A EP0927252B1 (en) 1996-05-01 1997-04-29 Antibodies against interferon alpha/beta receptor
PT97919622T PT927252E (pt) 1996-05-01 1997-04-29 Anticorpos contra o receptor do interferão alfa/beta
EA199800968A EA002543B1 (ru) 1996-05-01 1997-04-29 Антитела против рецептора интерферона-альфа/бета
UA98116315A UA76396C2 (en) 1996-05-01 1997-04-29 Monoclonal antibody, which is able to be bound with receptor ifn -, block the biological activity of ifn- and ifn- and create higher antiviral titer against fn-, than against ifn- (variants), pharmaceutical composition for modulation or blocking biological activity of ifn-, hybridoma expressing denoted antibody (variants), and set for carrying out elisa-analysis of ifnab-bpi and/or ifnab-bpi
BR9709202A BR9709202A (pt) 1996-05-01 1997-04-29 Anticorpos contra o receptor de interferon alfa/beta
JP53837897A JP4308322B2 (ja) 1996-05-01 1997-04-29 インターフェロンアルファ/ベータ受容体に対する抗体
CA2253239A CA2253239C (en) 1996-05-01 1997-04-29 Antibodies against interferon alpha/beta receptor
ES97919622T ES2274542T3 (es) 1996-05-01 1997-04-29 Anticuerpos frente al receptor del interferon alfa/beta.
CNB971951861A CN1198929C (zh) 1996-05-01 1997-04-29 抗α/β干扰素受体的抗体
EP06014510A EP1739177A1 (en) 1996-05-01 1997-04-29 Antibodies against interferon alpha/beta receptor
KR1020047011388A KR100581798B1 (ko) 1996-05-01 1997-04-29 인터페론 α 활성을 선택적으로 차단하는 인터페론 α/β수용체에 대한 항체
DK97919622T DK0927252T3 (da) 1996-05-01 1997-04-29 Antistoffer mod interferon-alfa-/beta-receptor
DE69736835T DE69736835T2 (de) 1996-05-01 1997-04-29 Antikörper gegen den interferon-alpha/beta-rezeptor.
KR1019980708393A KR20000064953A (ko) 1996-05-01 1997-04-29 인터페론 α/β수용체에 대한 항체
IL126835A IL126835A (en) 1996-05-01 1997-04-29 Interferon ALPHA / BETA receptor antibodies
AT97919622T ATE342981T1 (de) 1996-05-01 1997-04-29 Antikörper gegen den interferon-alpha/beta- rezeptor.
SI9730754T SI0927252T1 (sl) 1996-05-01 1997-04-29 Protitelesa proti receptorju za interferon alfa/beta
PCT/IL1997/000138 WO1997041229A1 (en) 1996-05-01 1997-04-29 Antibodies against interferon alpha/beta receptor
AU24027/97A AU719995B2 (en) 1996-05-01 1997-04-29 Antibodies against interferon alpha/beta receptor
US09/171,979 US6136309A (en) 1996-05-01 1998-04-29 Antibodies against the interferon (IFN) α/β receptor (IFNAR2) that preferentially block the activity of IFN-α
NO19985050A NO324206B1 (no) 1996-05-01 1998-10-29 Antistoffer mot interferon alfa-/beta-reseptorer og fremgangsmater for fremstilling og anvendelse derav, samt DNA-molekyl, ekspresjonsvektor, vertscelle, farmasoytisk sammensetning, hybridom og sett.
HK99104252A HK1019339A1 (en) 1996-05-01 1999-09-30 Antibodies against interferon alpha/beta receptor.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL11809696A IL118096A0 (en) 1996-05-01 1996-05-01 Antibodies against interferon alpha/beta receptor

Publications (1)

Publication Number Publication Date
IL118096A0 true IL118096A0 (en) 1996-09-12

Family

ID=11068814

Family Applications (2)

Application Number Title Priority Date Filing Date
IL11809696A IL118096A0 (en) 1996-05-01 1996-05-01 Antibodies against interferon alpha/beta receptor
IL126835A IL126835A (en) 1996-05-01 1997-04-29 Interferon ALPHA / BETA receptor antibodies

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL126835A IL126835A (en) 1996-05-01 1997-04-29 Interferon ALPHA / BETA receptor antibodies

Country Status (19)

Country Link
US (1) US6136309A (xx)
EP (2) EP0927252B1 (xx)
JP (1) JP4308322B2 (xx)
KR (2) KR100581798B1 (xx)
CN (1) CN1198929C (xx)
AT (1) ATE342981T1 (xx)
AU (1) AU719995B2 (xx)
BR (1) BR9709202A (xx)
CA (1) CA2253239C (xx)
DE (1) DE69736835T2 (xx)
DK (1) DK0927252T3 (xx)
EA (1) EA002543B1 (xx)
ES (1) ES2274542T3 (xx)
HK (1) HK1019339A1 (xx)
IL (2) IL118096A0 (xx)
NO (1) NO324206B1 (xx)
PT (1) PT927252E (xx)
UA (1) UA76396C2 (xx)
WO (1) WO1997041229A1 (xx)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0563487A1 (en) * 1992-03-31 1993-10-06 Laboratoire Europeen De Biotechnologie S.A. Monoclonal antibodies against the interferon receptor, with neutralizing activity against type I interferon
US6713609B1 (en) 1996-07-16 2004-03-30 Genentech, Inc. Monoclonal antibodies to type I interferon receptor
US6376067B1 (en) * 1998-12-21 2002-04-23 Mitsubishi Polyester Film, Llc Silicone coated film with back side slip control coating and method of controlling slip of such film
RU2181297C2 (ru) * 2000-06-20 2002-04-20 Эпштейн Олег Ильич Способ лечения патологического синдрома и лекарственное средство
DE60239522D1 (de) 2001-01-09 2011-05-05 Baylor Res Inst Dallas Verfahren zur behandlung von autoimmunerkrankungen bei einem probanden und diagnostische in-vitro-assays
AU2007202840B2 (en) * 2001-01-09 2011-07-28 Baylor Research Institute Methods for treating autoimmune diseases in a subject and in vitro diagnostic assays
US7087726B2 (en) 2001-02-22 2006-08-08 Genentech, Inc. Anti-interferon-α antibodies
UA76638C2 (en) 2002-08-02 2006-08-15 Oleh Illich Epshtein Homeopathic medication based on anti-interferon antibodies and method for treating a pathological syndrome associated with interferon
UA76640C2 (uk) * 2002-08-02 2006-08-15 Олєг Ільіч Епштєйн Спосіб корекції патологічних імунних реакцій та гомеопатичний лікарський засіб
UA76639C2 (uk) * 2002-08-02 2006-08-15 Олєг Ільіч Епштєйн Гомеопатичний лікарський засіб та спосіб лікування еректильних дисфункцій
AU2007203559B2 (en) * 2003-04-23 2010-09-02 E. R. Squibb & Sons, L.L.C. Compositions and methods for the therapy of inflammatory bowel disease
WO2004093908A2 (en) * 2003-04-23 2004-11-04 Medarex, Inc. Compositions and methods for the therapy of inflammatory bowel disease
CA2546054C (en) 2003-12-10 2014-05-13 Medarex, Inc. Interferon alpha antibodies and their uses
KR101541658B1 (ko) 2004-06-21 2015-08-07 메다렉스, 엘.엘.시. 인터페론 알파 수용체 1 항체 및 그의 용도
KR101363120B1 (ko) * 2005-02-10 2014-02-13 베일러 리서치 인스티튜트 항-인터페론 알파 모노클로날 항체 및 사용 방법
US7888481B2 (en) * 2005-02-10 2011-02-15 Baylor Research Institute Anti-interferon alpha monoclonal antibodies and methods for use
MX2007016343A (es) * 2005-06-22 2008-03-05 Genentech Inc Metodos y composiciones para ser blanco en ifnar2.
WO2009135861A2 (en) * 2008-05-07 2009-11-12 Novo Nordisk A/S Humanized antibodies against human interferon-alpha
FR2962656A1 (fr) 2010-07-15 2012-01-20 Oleg Iliich Epshtein Procede pour augmenter l'effet d'une forme activee-potentialisee d'un anticorps
SG187035A1 (en) 2010-07-15 2013-02-28 Oleg Iliich Epshtein Combination pharmaceutical composition and methods of treating functional diseases or conditions of gastrointestinal tract
CN108409862B (zh) * 2016-07-14 2021-07-13 中国科学院生物物理研究所 I型干扰素受体抗体及其用途
CN115558027B (zh) * 2022-12-05 2023-02-28 北京万泰生物药业股份有限公司 一种核酸酶的单克隆抗体及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0563487A1 (en) * 1992-03-31 1993-10-06 Laboratoire Europeen De Biotechnologie S.A. Monoclonal antibodies against the interferon receptor, with neutralizing activity against type I interferon
IL106591A (en) * 1992-09-03 2008-03-20 Yeda Res & Dev Interferon alpha/beta binding protein, its preparation and pharmaceutical compositions containing it
IL108584A (en) * 1994-02-07 2008-03-20 Yeda Res & Dev Cloning of the interferon-binding protein ALPHA / BETA
EP0725654A1 (en) * 1993-09-17 1996-08-14 Laboratoire Europeen De Biotechnologie S.A. Pharmaceutical composition comprising monoclonal antibodies against the interferon receptor, with neutralizing activity against type i interferon

Also Published As

Publication number Publication date
CN1220699A (zh) 1999-06-23
PT927252E (pt) 2007-01-31
KR100581798B1 (ko) 2006-05-25
EP0927252B1 (en) 2006-10-18
EA002543B1 (ru) 2002-06-27
JP2000509276A (ja) 2000-07-25
KR20000064953A (ko) 2000-11-06
ATE342981T1 (de) 2006-11-15
EP1739177A1 (en) 2007-01-03
EA199800968A1 (ru) 1999-04-29
NO324206B1 (no) 2007-09-10
DK0927252T3 (da) 2007-02-05
CN1198929C (zh) 2005-04-27
DE69736835D1 (de) 2006-11-30
ES2274542T3 (es) 2007-05-16
EP0927252A1 (en) 1999-07-07
BR9709202A (pt) 1999-08-10
NO985050L (no) 1998-12-29
JP4308322B2 (ja) 2009-08-05
DE69736835T2 (de) 2007-11-22
WO1997041229A1 (en) 1997-11-06
AU2402797A (en) 1997-11-19
IL126835A (en) 2007-07-24
UA76396C2 (en) 2006-08-15
CA2253239C (en) 2010-08-10
AU719995B2 (en) 2000-05-18
US6136309A (en) 2000-10-24
HK1019339A1 (en) 2000-02-03
NO985050D0 (no) 1998-10-29
KR20040075105A (ko) 2004-08-26
CA2253239A1 (en) 1997-11-06

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