IL104304A - Transgenic animal models for alzheimer's disease - Google Patents
Transgenic animal models for alzheimer's diseaseInfo
- Publication number
- IL104304A IL104304A IL10430493A IL10430493A IL104304A IL 104304 A IL104304 A IL 104304A IL 10430493 A IL10430493 A IL 10430493A IL 10430493 A IL10430493 A IL 10430493A IL 104304 A IL104304 A IL 104304A
- Authority
- IL
- Israel
- Prior art keywords
- promoter
- app
- app770
- cdna
- transgenic
- Prior art date
Links
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- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
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- A01K67/0278—Knock-in vertebrates, e.g. humanised vertebrates
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
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- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
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- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
- A01K2267/0306—Animal model for genetic diseases
- A01K2267/0312—Animal model for Alzheimer's disease
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US (2) | US5720936A (fr) |
EP (1) | EP0620849B1 (fr) |
JP (3) | JPH07506720A (fr) |
AT (1) | ATE243746T1 (fr) |
AU (1) | AU671093B2 (fr) |
CA (1) | CA2127450C (fr) |
DE (1) | DE69233109T2 (fr) |
DK (1) | DK0620849T3 (fr) |
ES (1) | ES2204899T3 (fr) |
IL (1) | IL104304A (fr) |
PT (1) | PT620849E (fr) |
WO (1) | WO1993014200A1 (fr) |
Families Citing this family (184)
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US5586226A (en) * | 1990-05-16 | 1996-12-17 | Canon Kabushiki Kaisha | Control method and device for a unicolor printer |
US5912410A (en) * | 1990-06-15 | 1999-06-15 | Scios Inc. | Transgenic non-human mice displaying the amyloid-forming pathology of alzheimer's disease |
JP3510244B2 (ja) * | 1991-01-21 | 2004-03-22 | エラン ファーマシューティカルス,インコーポレイテッド | アルツハイマー病に関するテストおよびモデル |
ATE243746T1 (de) * | 1992-01-07 | 2003-07-15 | Elan Pharm Inc | Transgene tiermodelle fur alzheimer-krankheit |
US6610493B1 (en) | 1993-06-17 | 2003-08-26 | Brigham And Women's Hospital | Screening compounds for the ability to alter the production of amyloid-β peptide |
US6264915B1 (en) | 1992-09-13 | 2001-07-24 | The President And Fellows Of Harvard College | Process for detecting potential carcinogens |
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1992
- 1992-12-29 AT AT93901093T patent/ATE243746T1/de active
- 1992-12-29 JP JP5512475A patent/JPH07506720A/ja active Pending
- 1992-12-29 EP EP93901093A patent/EP0620849B1/fr not_active Expired - Lifetime
- 1992-12-29 PT PT93901093T patent/PT620849E/pt unknown
- 1992-12-29 WO PCT/US1992/011276 patent/WO1993014200A1/fr active IP Right Grant
- 1992-12-29 AU AU33360/93A patent/AU671093B2/en not_active Expired
- 1992-12-29 DK DK93901093T patent/DK0620849T3/da active
- 1992-12-29 DE DE69233109T patent/DE69233109T2/de not_active Expired - Lifetime
- 1992-12-29 ES ES93901093T patent/ES2204899T3/es not_active Expired - Lifetime
- 1992-12-29 CA CA002127450A patent/CA2127450C/fr not_active Expired - Lifetime
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1993
- 1993-01-04 IL IL10430493A patent/IL104304A/en not_active IP Right Cessation
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1994
- 1994-07-29 US US08/282,227 patent/US5720936A/en not_active Expired - Lifetime
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AU3336093A (en) | 1993-08-03 |
AU671093B2 (en) | 1996-08-15 |
CA2127450A1 (fr) | 1993-07-22 |
DK0620849T3 (da) | 2003-10-20 |
ATE243746T1 (de) | 2003-07-15 |
DE69233109D1 (de) | 2003-07-31 |
EP0620849A1 (fr) | 1994-10-26 |
WO1993014200A1 (fr) | 1993-07-22 |
EP0620849B1 (fr) | 2003-06-25 |
CA2127450C (fr) | 2007-04-17 |
PT620849E (pt) | 2003-11-28 |
US5811633A (en) | 1998-09-22 |
JP2007267742A (ja) | 2007-10-18 |
DE69233109T2 (de) | 2004-05-19 |
IL104304A0 (en) | 1993-05-13 |
JPH07506720A (ja) | 1995-07-27 |
ES2204899T3 (es) | 2004-05-01 |
US5720936A (en) | 1998-02-24 |
JP2004089187A (ja) | 2004-03-25 |
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