IL101233A - Receptor-based screening and identifying methods for amylin agonists and antagonists - Google Patents

Receptor-based screening and identifying methods for amylin agonists and antagonists

Info

Publication number: IL101233A
Authority: IL; Israel
Prior art keywords: amylin; receptor; antagonists; based screening; amylin agonists
Prior art date: 1991-03-15

Application number

IL101233A

Other languages

English (en)

Other versions

IL101233A0 (en

Original Assignee

Amylin Pharmaceuticals Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-03-15

Filing date

1992-03-15

Publication date

1997-04-15

1992-03-15 Application filed by Amylin Pharmaceuticals Inc filed Critical Amylin Pharmaceuticals Inc

1992-03-15 Priority to IL12008192A priority Critical patent/IL120081A/en

1992-03-15 Priority to IL12008292A priority patent/IL120082A/en

1992-11-15 Publication of IL101233A0 publication Critical patent/IL101233A0/xx

1997-01-27 Priority to IL12008197A priority patent/IL120081A0/xx

1997-01-27 Priority to IL12008297A priority patent/IL120082A0/xx

1997-04-15 Publication of IL101233A publication Critical patent/IL101233A/xx

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Epidemiology (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Diabetes (AREA)
Pharmacology & Pharmacy (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Endocrinology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Investigating Or Analysing Biological Materials (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Other Investigation Or Analysis Of Materials By Electrical Means (AREA)

IL101233A 1991-03-15 1992-03-15 Receptor-based screening and identifying methods for amylin agonists and antagonists IL101233A (en)

Priority Applications (4)

Application Number	Priority Date	Filing Date	Title
IL12008192A IL120081A (en)	1991-03-15	1992-03-15	Methods for determining trait-related properties of amylin agonists and antagonists
IL12008292A IL120082A (en)	1991-03-15	1992-03-15	A method for determining the amount of a substance that binds to an amylin receptor in the sample
IL12008197A IL120081A0 (en)	1991-03-15	1997-01-27	Assay for evaluating the receptor binding characteristics of amylin agonists and antagonists
IL12008297A IL120082A0 (en)	1991-03-15	1997-01-27	Method for determining the amount of an amylin receptor binding compound in a sample

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/670,231 US5264372A (en)	1991-03-15	1991-03-15	Receptor-based screening methods for amylin agonists and antagonists

Publications (2)

Publication Number	Publication Date
IL101233A0 IL101233A0 (en)	1992-11-15
IL101233A true IL101233A (en)	1997-04-15

Family

ID=24689539

Family Applications (5)

Application Number	Title	Priority Date	Filing Date
IL12008292A IL120082A (en)	1991-03-15	1992-03-15	A method for determining the amount of a substance that binds to an amylin receptor in the sample
IL101233A IL101233A (en)	1991-03-15	1992-03-15	Receptor-based screening and identifying methods for amylin agonists and antagonists
IL12008192A IL120081A (en)	1991-03-15	1992-03-15	Methods for determining trait-related properties of amylin agonists and antagonists
IL12008197A IL120081A0 (en)	1991-03-15	1997-01-27	Assay for evaluating the receptor binding characteristics of amylin agonists and antagonists
IL12008297A IL120082A0 (en)	1991-03-15	1997-01-27	Method for determining the amount of an amylin receptor binding compound in a sample

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
IL12008292A IL120082A (en)	1991-03-15	1992-03-15	A method for determining the amount of a substance that binds to an amylin receptor in the sample

Family Applications After (3)

Application Number	Title	Priority Date	Filing Date
IL12008192A IL120081A (en)	1991-03-15	1992-03-15	Methods for determining trait-related properties of amylin agonists and antagonists
IL12008197A IL120081A0 (en)	1991-03-15	1997-01-27	Assay for evaluating the receptor binding characteristics of amylin agonists and antagonists
IL12008297A IL120082A0 (en)	1991-03-15	1997-01-27	Method for determining the amount of an amylin receptor binding compound in a sample

Country Status (13)

Country	Link
US (1)	US5264372A (xx)
EP (1)	EP0529065B1 (xx)
JP (1)	JPH05508226A (xx)
AT (1)	ATE172540T1 (xx)
AU (1)	AU1663092A (xx)
CA (1)	CA2082929A1 (xx)
DE (1)	DE69227347T2 (xx)
DK (1)	DK0529065T3 (xx)
IL (5)	IL120082A (xx)
MX (1)	MX9201113A (xx)
TW (1)	TW324064B (xx)
WO (1)	WO1992016845A1 (xx)
ZA (1)	ZA921884B (xx)

Families Citing this family (42)

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Publication number	Priority date	Publication date	Assignee	Title
US5580953A (en) *	1991-08-14	1996-12-03	Amylin Pharmaceuticals, Inc.	Amylin antagonist peptides and uses therefor
EP0594843B1 (en) *	1992-05-15	2004-11-03	Amylin Pharmaceuticals, Inc.	Antibody assay for amylin
AU6249594A (en) *	1993-02-12	1994-08-29	Amylin Pharmaceuticals, Inc.	Mcf-7 binding site assays
AU6524794A (en) *	1993-03-24	1994-10-11	Amylin Pharmaceuticals, Inc.	Cloned receptors and methods for screening
GB9317193D0 (en) *	1993-08-18	1993-10-06	Zeneca Ltd	Method
CZ69596A3 (en) *	1993-09-07	1997-06-11	Amylin Pharmaceuticals Inc	Application of amylin, amylin agonist, amylin analog agonist or amylin antagonist for preparing a pharmaceutical preparation used for the control of gastrointestinal motility
US7115728B1 (en)	1995-01-30	2006-10-03	Ligand Pharmaceutical Incorporated	Human peroxisome proliferator activated receptor γ
AU5539596A (en) *	1995-04-06	1996-10-23	Amylin Pharmaceuticals, Inc.	Anti-obesity agents
US5739106A (en) *	1995-06-07	1998-04-14	Rink; Timothy J.	Appetite regulating compositions
US6143718A (en) *	1995-06-07	2000-11-07	Amylin Pharmaceuticals, Inc.	Treatment of Type II diabetes mellutis with amylin agonists
ATE493998T1 (de) *	1996-08-08	2011-01-15	Amylin Pharmaceuticals Inc	Pharmazeutische zusammensetzung mit einem exendin-4-peptid
US5677279A (en) *	1996-12-16	1997-10-14	Amylin Pharmaceuticals, Inc.	Methods and compositions for treating pain with amylin or agonists thereof
AU739020B2 (en)	1997-01-07	2001-10-04	Amylin Pharmaceuticals, Inc.	Use of exendins and agonists thereof for the reduction of food intake
US7101853B2 (en)	1997-05-06	2006-09-05	Amylin Pharmaceuticals, Inc.	Method for treating or preventing gastritis using amylin or amylin agonists
US7910548B2 (en)	1997-06-06	2011-03-22	Amylin Pharmaceuticals, Inc.	Methods for treating obesity
WO1999005161A1 (en) *	1997-07-25	1999-02-04	Ligand Pharmaceuticals Incorporated	HUMAN PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA (PPARη) GENE REGULATORY SEQUENCES AND USES THEREFOR
US6936584B1 (en)	1998-02-13	2005-08-30	Amylin Pharmaceuticals, Inc.	Mixed amylin activity compounds
EP1100888A2 (en) *	1998-05-26	2001-05-23	University Of Medicine And Dentistry Of New Jersey	System for reproducing and modulating stability and turnover of rna molecules
US7399489B2 (en) *	1999-01-14	2008-07-15	Amylin Pharmaceuticals, Inc.	Exendin analog formulations
DE60032331T2 (de)	1999-01-14	2007-06-21	Amylin Pharmaceuticals, Inc., San Diego	Exendine zur glucagon suppression
US20030087820A1 (en) *	1999-01-14	2003-05-08	Young Andrew A.	Novel exendin agonist formulations and methods of administration thereof
US6924264B1 (en) *	1999-04-30	2005-08-02	Amylin Pharmaceuticals, Inc.	Modified exendins and exendin agonists
BR0010705A (pt)	1999-04-30	2002-02-05	Amylin Pharmaceuticals Inc	Exendinas modificadas e agonistas da exendina
JP2003513281A (ja) *	1999-07-13	2003-04-08	アミリン・ファーマシューティカルズ，インコーポレイテッド	治療用化合物を同定するための最後野由来の膜、細胞および組織の使用
WO2002030471A2 (en) *	2000-10-10	2002-04-18	Institut für Virologie Teilrechtsfähiges Institut an der Veterinärmedizinischen Universität Wien	A novel system for the evaluation of the activity and/or specificity of a viral component
US20040005997A1 (en) *	2002-06-27	2004-01-08	The Procter & Gamble Company	Methods for identifying compounds for regulating muscle mass of function using amylin receptors
EP1529061B1 (en) *	2002-08-06	2008-02-13	Sanofi-Aventis Deutschland GmbH	Method for isolating an intestinal cholesterol binding protein
US8168233B2 (en) *	2002-10-18	2012-05-01	Amylin Pharmaceuticals, Inc.	Treatment of pancreatitis with amylin
US20040214180A1 (en) *	2003-04-28	2004-10-28	Hironori Kobayashi	Method and kit for determining quantity of protein
EP1663289A2 (en) *	2003-08-29	2006-06-07	Amylin Pharmaceuticals, Inc.	Methods for treating or ameliorating ghrelin-associated diseases and disorders
US8114958B2 (en) *	2004-02-11	2012-02-14	Amylin Pharmaceuticals, Inc.	Amylin family peptides
US7399744B2 (en) *	2004-03-04	2008-07-15	Amylin Pharmaceuticals, Inc.	Methods for affecting body composition
JP2008515443A (ja)	2004-10-08	2008-05-15	アミリン・ファーマシューティカルズ，インコーポレイテッド	新規のアミリンファミリーポリペプチド−６（ａｆｐ−６）アナログならびにそれらの製法および使用方法
DE102004051014A1 (de) *	2004-10-20	2006-04-27	Rwth Aachen	Chemisch modifizierte Peptidanaloga
US8394765B2 (en) *	2004-11-01	2013-03-12	Amylin Pharmaceuticals Llc	Methods of treating obesity with two different anti-obesity agents
EP2127676A3 (en)	2004-11-01	2013-09-04	Amylin Pharmaceuticals, LLC	Treatment of obesity and related disorders
US7879572B2 (en) *	2004-11-12	2011-02-01	Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College	Regulation of F1-ATPase beta subunit cellular location
US7879794B2 (en)	2005-03-31	2011-02-01	Amylin Pharmaceuticals, Inc.	Methods for controlling binge eating disorders
EP1912666A2 (en) *	2005-07-22	2008-04-23	Amylin Pharmaceuticals, Inc.	Use of amylin and amylin agonists as cardioprotective or myoprotective agents
EA201070609A1 (ru) *	2007-11-14	2010-12-30	Амилин Фармасьютикалз, Инк.	Способы лечения ожирения и ассоциированных с ожирением заболеваний и расстройств
CN102770152B (zh)	2009-11-25	2016-07-06	阿瑞斯根股份有限公司	肽类的粘膜递送
WO2015004632A1 (en) *	2013-07-12	2015-01-15	Neotope Biosciences Limited	Antibodies that recognize iapp

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4434236A (en) *	1982-10-20	1984-02-28	E. I. Du Pont De Nemours & Co.	Immunoassay wherein labeled antibody is displaced from immobilized analyte-analogue
DE68924372T2 (de) *	1988-01-11	1996-05-09	Amylin Pharmaceuticals Inc	Behandlung von diabetes mellitus typ 2.
ES2080802T3 (es) *	1989-07-10	1996-02-16	Amylin Pharmaceuticals Inc	Uso de un antagonista de amilina en la preparacion de un medicamento para el tratamiento de la obesidad e hipertension intrinseca y desordenes asociados.

1991
- 1991-03-15 US US07/670,231 patent/US5264372A/en not_active Expired - Lifetime
1992
- 1992-03-13 WO PCT/US1992/002125 patent/WO1992016845A1/en active IP Right Grant
- 1992-03-13 AT AT92908951T patent/ATE172540T1/de not_active IP Right Cessation
- 1992-03-13 CA CA002082929A patent/CA2082929A1/en not_active Abandoned
- 1992-03-13 ZA ZA921884A patent/ZA921884B/xx unknown
- 1992-03-13 TW TW081101911A patent/TW324064B/zh not_active IP Right Cessation
- 1992-03-13 DE DE69227347T patent/DE69227347T2/de not_active Expired - Fee Related
- 1992-03-13 JP JP92508815A patent/JPH05508226A/ja active Pending
- 1992-03-13 DK DK92908951T patent/DK0529065T3/da active
- 1992-03-13 MX MX9201113A patent/MX9201113A/es unknown
- 1992-03-13 EP EP92908951A patent/EP0529065B1/en not_active Expired - Lifetime
- 1992-03-13 AU AU16630/92A patent/AU1663092A/en not_active Abandoned
- 1992-03-15 IL IL12008292A patent/IL120082A/en not_active IP Right Cessation
- 1992-03-15 IL IL101233A patent/IL101233A/xx not_active IP Right Cessation
- 1992-03-15 IL IL12008192A patent/IL120081A/en not_active IP Right Cessation
1997
- 1997-01-27 IL IL12008197A patent/IL120081A0/xx unknown
- 1997-01-27 IL IL12008297A patent/IL120082A0/xx unknown

Also Published As

Publication number	Publication date
US5264372A (en)	1993-11-23
TW324064B (en)	1998-01-01
JPH05508226A (ja)	1993-11-18
IL120081A0 (en)	1997-04-15
DE69227347D1 (de)	1998-11-26
EP0529065B1 (en)	1998-10-21
ZA921884B (en)	1993-08-03
AU1663092A (en)	1992-10-21
EP0529065A4 (en)	1993-10-20
IL120082A (en)	1998-12-27
EP0529065A1 (en)	1993-03-03
IL120082A0 (en)	1997-04-15
MX9201113A (es)	1992-10-01
ATE172540T1 (de)	1998-11-15
DK0529065T3 (da)	1999-06-28
WO1992016845A1 (en)	1992-10-01
IL120081A (en)	1998-12-27
CA2082929A1 (en)	1992-09-16
IL101233A0 (en)	1992-11-15
DE69227347T2 (de)	1999-03-18

Legal Events

Date	Code	Title
1997-11-20	FF	Patent granted
1998-09-24	KB	Patent renewed
2006-06-18	KB	Patent renewed
2010-10-31	KB	Patent renewed
2012-11-29	EXP	Patent expired

Publication	Publication Date	Title
IL101233A (en)	1997-04-15	Receptor-based screening and identifying methods for amylin agonists and antagonists
NO172517C (no)	1993-07-28	Immunoanalyse for bestemmelse av analyttkonsentrasjon i en vaeskeproeve og sett for gjennomfoering av fremgangsmaaten
NO903124D0 (no)	1990-07-13	Testmetode og reagenssett for denne.
CA2007532A1 (en)	1990-07-10	Threshold ligand-receptor assay
DE3580640D1 (de)	1991-01-03	Testverfahren.
TW370614B (en)	1999-09-21	Oligomerized antibodies, method of immunological determination using the same and reagent kit comprising the same
ATE185424T1 (de)	1999-10-15	Differentielle bindungsaffinitäten und darauf beruhende dissoziationstestverfahren
EP0217403A3 (en)	1988-06-22	Solid-phase analytical device and method for using same
ES2112916T3 (es)	1998-04-16	Ensayo de union que utiliza un reactivo marcado.
ES8700882A1 (es)	1986-02-01	Un metodo de inmuno ensayo heterogeneo con calibracion simultanea.
DE69416828D1 (de)	1999-04-08	Vorrichtung zur chromatographischen bestimmung, die einander entgegenstellbare teile enthalten
ES8703022A1 (es)	1987-01-16	Procedimiento para detectar al menos un analite en una muestra unica sospechosa de contener mas de un analito.
IE841371L (en)	1984-12-03	Carrier matrix analytical test device
ATE208900T1 (de)	2001-11-15	Verringerung des hook-effekts in immuntests mit teilchenförmigem trägermaterial
ATE310956T1 (de)	2005-12-15	Festphasenverfahren und testsatz zur antigen- und antikörperprüfung in der blutgruppen-serologie
EP0829723A3 (de)	1998-06-03	Homogene Nachweisverfahren zur Bestimmung von Subpopulationen eines Analyten
AU2375695A (en)	1995-11-29	Solid-phase filtration method for antigen and antibody assays in bloodgroup serology, and test kit
WO1999055901A3 (en)	2000-04-20	Screening assay for identifying human purinoreceptor ligands
ATE283490T1 (de)	2004-12-15	Cobalamintest
DE59913689D1 (de)	2006-08-31	Verbesserung von bindeassays durch multiepitopanalyse
EP0757251A3 (en)	1999-07-07	Estimation of change in bone mineral density and diagnosis of osteoporosis