IE872105L - Benzhydrylthiomethane derivatives - Google Patents

Benzhydrylthiomethane derivatives

Info

Publication number
IE872105L
IE872105L IE210587A IE210587A IE872105L IE 872105 L IE872105 L IE 872105L IE 210587 A IE210587 A IE 210587A IE 210587 A IE210587 A IE 210587A IE 872105 L IE872105 L IE 872105L
Authority
IE
Ireland
Prior art keywords
therapeutic composition
active principle
benzhydrylthiomethane
composition according
nhoh
Prior art date
Application number
IE210587A
Other versions
IE60234B1 (en
Original Assignee
Lafon Labor
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8611683A external-priority patent/FR2602768B1/en
Application filed by Lafon Labor filed Critical Lafon Labor
Publication of IE872105L publication Critical patent/IE872105L/en
Publication of IE60234B1 publication Critical patent/IE60234B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/15—Oximes (>C=N—O—); Hydrazines (>N—N<); Hydrazones (>N—N=) ; Imines (C—N=C)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1. Claims for the Contracting States BE, CH, DE, FR, GB, IT, LI, LU, NL, SE Therapeutic compositions containing as active principle a derivative of benzhydrylthiomethane having the Formula : see diagramm : EP0258134,P10,F2 where Y denotes a -CONH2 , -CO-NHOH or -CH=N-OH group, and R1 and R2 denote a hydrogen or fluorine atom independently of one another. 1. Claims for the Contracting States AT, GR, SP A process for the preparation of a therapeutic composition, characterized in that a pharmaceutically acceptable form is given to a derivative of benzhydrylthiomethane having the Formula : see diagramm : EP0258134,P10,F3 where Y denotes a -CONH2 , -CO-NHOH or -CH=N-OH group, and R1 and R2 denote a hydrogen or fluorine atom independently of one another. [EP0258134A1]

Claims (5)

1. Therapeutic composition containing as active principle a derivative of benzhydrylthioaethane with the formula in which Y represents a group -COM2? -CO-NHOH or -CH=N-OH, and R~j and represent independently of each other a hydrogen or a fluorine atom.
2. Therapeutic composition according to Claim 1, containing as active principle 2-(4,4s-difluorobenzhydrylthio) acetamide.
3. Therapeutic composition according to Claim 1, containing as active principle 2-(benzhydrylthio)acetamide-
4- Therapeutic composition according to Claim 1 „ containing as active principle 2-(benzhydrylthio)acetaldoxims
5. A therapeutic composition according to Claim 1, substantially as hereinbefore described with particular reference to the accompanying Examples. II Dated this the 5th day of August, 19 87 F. R» KELLY & CO. EXECUTIVE 27 Clyde Road, Ballsbridge, Dublin 4 AGENTS FOR THE APPLICANTS
IE210587A 1986-08-13 1987-08-05 Therapeutic compositions containing benzhydrylthiomethane derivatives IE60234B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8611683A FR2602768B1 (en) 1986-08-13 1986-08-13 2- (4,4'-DIFLUORO BENZHYDRYL THIO) ACETIC ACID DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC APPLICATIONS
FR8615129A FR2606015B1 (en) 1986-08-13 1986-10-30 BENZHYDRYLTHIOMETHANE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THERAPEUTIC APPLICATIONS

Publications (2)

Publication Number Publication Date
IE872105L true IE872105L (en) 1988-02-13
IE60234B1 IE60234B1 (en) 1994-06-15

Family

ID=26225439

Family Applications (1)

Application Number Title Priority Date Filing Date
IE210587A IE60234B1 (en) 1986-08-13 1987-08-05 Therapeutic compositions containing benzhydrylthiomethane derivatives

Country Status (6)

Country Link
EP (1) EP0258134B1 (en)
DE (1) DE3762800D1 (en)
DK (1) DK174358B1 (en)
FR (1) FR2606015B1 (en)
GR (1) GR3000526T3 (en)
IE (1) IE60234B1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2707637B1 (en) * 1993-06-30 1995-10-06 Lafon Labor New acetamide derivatives, their preparation process and their use in therapy.
FR2708201B1 (en) * 1993-06-30 1995-10-20 Lafon Labor Use of acetamide derivatives for the manufacture of medicaments.
DK1309547T3 (en) 2000-07-27 2007-05-21 Teva Pharma Crystalline and pure modafinil and process for making the same
CN104059004A (en) * 2014-06-25 2014-09-24 江苏斯威森生物医药工程研究中心有限公司 Method for preparing 2-[(4,4'-dihalo-diphenyl methyl) sulfydryl] acetate
KR102126389B1 (en) * 2018-09-14 2020-06-25 셀라이온바이오메드 주식회사 A composition for preventing or treating liver diseases comprising benzhydrylthio acetamide derivative as an active ingredient

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1520812A (en) * 1975-10-02 1978-08-09 Lafon Labor Benzhydrylsulphinyl derivatives
GB1584462A (en) * 1977-03-31 1981-02-11 Lafon Labor N-diaryl-malonamide and diarylmethyl-sulphinyl-acetamide derivatives and pharmaceutical compositions containing them
DE2814445A1 (en) * 1978-04-04 1979-10-11 Union Carbide Corp Organic sulphone prodn. from corresp. sulphide - by oxidn. with aq. peracid, esp. for pesticides prodn.
FR2528041A1 (en) * 1982-06-04 1983-12-09 Lafon Labor HALOGENOBENZHYDRYLSULFINYLACETOHYDROXAMIC ACIDS, PREPARATION METHOD AND THERAPEUTIC USE
FR2528038B2 (en) * 1982-06-04 1985-08-09 Lafon Labor BENZHYDRYLSULFINYLACETAMIDE DERIVATIVES AND THEIR THERAPEUTIC USE

Also Published As

Publication number Publication date
DK174358B1 (en) 2002-12-30
DK415087D0 (en) 1987-08-10
EP0258134B1 (en) 1990-05-23
GR3000526T3 (en) 1991-07-31
EP0258134A1 (en) 1988-03-02
DK415087A (en) 1988-02-14
IE60234B1 (en) 1994-06-15
DE3762800D1 (en) 1990-06-28
FR2606015B1 (en) 1989-05-19
FR2606015A1 (en) 1988-05-06

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Legal Events

Date Code Title Description
MK9A Patent expired