IE38515L - Cyclopentane (prostanoic acid) derivatives - Google Patents
Cyclopentane (prostanoic acid) derivativesInfo
- Publication number
- IE38515L IE38515L IE732066A IE206673A IE38515L IE 38515 L IE38515 L IE 38515L IE 732066 A IE732066 A IE 732066A IE 206673 A IE206673 A IE 206673A IE 38515 L IE38515 L IE 38515L
- Authority
- IE
- Ireland
- Prior art keywords
- trimethylsilyloxy
- trans
- cis
- epi
- trimethylsilyl
- Prior art date
Links
- -1 Cyclopentane (prostanoic acid) derivatives Chemical class 0.000 title abstract 13
- 125000000026 trimethylsilyl group Chemical group [H]C([H])([H])[Si]([*])(C([H])([H])[H])C([H])([H])[H] 0.000 abstract 11
- 125000005979 2-naphthyloxy group Chemical group 0.000 abstract 2
- 238000010561 standard procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
- C07C45/516—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of nitrogen-containing compounds to >C = O groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
- C07C49/743—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups having unsaturation outside the rings, e.g. humulones, lupulones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/753—Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Furan Compounds (AREA)
- Pyrane Compounds (AREA)
Abstract
1402035 Silylated prostadienoates IMPERIAL CHEMICAL INDUSTRIES Ltd 13 Nov 1973 [7 Dec 1972] 56501/72 Heading C3S [Also in Divisions C2 and A5] Trimethylsilyl 16 - (3 - chlorophenoxy)- 9,11α,15 - tri(trimethylsilyloxy) - 17,18,19,20- tetranor - 5 - cis,13 - trans - 12 - epi - prostadienoate, trimethylsilyl 16 - (3 - chlorophenoxy) - 9 - methoxyimino - 11α,15 - di(trimethylsilyloxy) - 17,18,19,20 - tetranor - 5 - cis,13- trans - 12 - epi - prostadienoate, trimethylsilyl 16 - (3 - chlorophenoxy) - 2 - methyl - 9 - methoxyimino - - 11α,15 - di(trimethylsilyloxy)- 17,18,19,20 - tetranot - 5 - cis,13 trans - 12- epi - prostadienoate, trimethylsilyl 9,11α,15- tri(trimethylsilyloxy) - 5 - cis,13 - trans - 12- epi - prostadienoate, 9 - methoxyimino - 11α, 15- di(trimethylsilyloxy) - 5 - cis,13 - trans - 12 - epiprostadienoate, trimethylsilyl 2 - methyl - 9α,- 11α,15 - tri(trimethylsilyloxy) - 5 - cis,13- trans - 12 - epi - prostadienoate, trimethylsilyl 9 - methoxyimino - 2 - methyl - 11α,15 - di- (trimethylsilyloxy) - 5 - cis,13 - trans - 12 - epiprostadienoate, trimethylsilyl 20 - ethyl- 9α,11α,15 - tri(trimethylsilyloxy) - 5 - cis,13- trans - 12 - epi - prostadienoate, trimethysilyl 9 - methoxyimino - 11α,15 - di(trimethylsilyloxy) - 13 - trans - 12 - epi - prostenoate, trimethylsilyl 9α,11α,15 - tri(trimethylsilyloxy)- 13 - trans - 12 - epi - prostenoate, trimethylsilyl 16 - phenyl - 9α,11α,15 - tri(trimethylsilyloxy)- 17,18,19,20 - tetranor - 5 - cis,13 - trans - 12- epi - prostadienoate, 9 - methoxyimino - 16- phenyl - 11α,15 - di(trimethylsilyloxy) - 17,18,- 19, 20 - tetranor - 5 - cis,13 - trans - 12 - epiprostadienoate, trimethylsilyl 16 - (2 - naphthyloxy) - 9α,11α,15 - tri(trimethylsilyloxy)- 17,18,19,20 - tetranor - 5 - cis,13 - trans - 12- epi - prostadienoate and trimethylsilyl 16- (2 - naphthyloxy) - 11α,15 - di(trimethylsilyloxy) - 17,18,19,20 - tetranor - 5 - cis,13 - trans- 12 - epi - prostadienoate are prepared by standard methods.
[GB1402035A]
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB5650172A GB1402035A (en) | 1972-12-07 | 1972-12-07 | Cyclopentane derivatives |
Publications (2)
Publication Number | Publication Date |
---|---|
IE38515L true IE38515L (en) | 1974-06-07 |
IE38515B1 IE38515B1 (en) | 1978-03-29 |
Family
ID=10476784
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IE2066/73A IE38515B1 (en) | 1972-12-07 | 1973-11-15 | Cyclopentane derivatives |
Country Status (13)
Country | Link |
---|---|
JP (1) | JPS5024252A (en) |
AU (1) | AU473283B2 (en) |
BE (1) | BE808398A (en) |
CA (1) | CA1016940A (en) |
CH (1) | CH605725A5 (en) |
DE (1) | DE2360893A1 (en) |
ES (1) | ES421274A1 (en) |
FR (1) | FR2209569B1 (en) |
GB (1) | GB1402035A (en) |
IE (1) | IE38515B1 (en) |
LU (1) | LU68940A1 (en) |
NL (1) | NL7316508A (en) |
ZA (1) | ZA738797B (en) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0144459A1 (en) * | 1983-12-09 | 1985-06-19 | Dr. Willmar Schwabe GmbH & Co. | Prostaglandins, their preparation and pharmaceutical compositions |
JPS6240987A (en) * | 1985-08-20 | 1987-02-21 | Nippon Steel Corp | Energy beam welding method |
US5972991A (en) | 1992-09-21 | 1999-10-26 | Allergan | Cyclopentane heptan(ene) oic acid, 2-heteroarylalkenyl derivatives as therapeutic agents |
US5688819A (en) * | 1992-09-21 | 1997-11-18 | Allergan | Cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl derivatives as therapeutic agents |
US5352708A (en) * | 1992-09-21 | 1994-10-04 | Allergan, Inc. | Non-acidic cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl derivatives as therapeutic agents |
US7851504B2 (en) | 2005-03-16 | 2010-12-14 | Allergan, Inc. | Enhanced bimatoprost ophthalmic solution |
WO2010102078A1 (en) | 2009-03-04 | 2010-09-10 | Allergan, Inc. | Enhanced bimatoprost ophthalmic solution |
US9522153B2 (en) | 2009-12-22 | 2016-12-20 | Allergan, Inc. | Compositions and methods for lowering intraocular pressure |
-
1972
- 1972-12-07 GB GB5650172A patent/GB1402035A/en not_active Expired
-
1973
- 1973-11-15 IE IE2066/73A patent/IE38515B1/en unknown
- 1973-11-16 ZA ZA738797*A patent/ZA738797B/en unknown
- 1973-11-19 CA CA186,104A patent/CA1016940A/en not_active Expired
- 1973-11-22 AU AU62797/73A patent/AU473283B2/en not_active Expired
- 1973-12-03 NL NL7316508A patent/NL7316508A/xx not_active Application Discontinuation
- 1973-12-05 FR FR7343446A patent/FR2209569B1/fr not_active Expired
- 1973-12-05 LU LU68940A patent/LU68940A1/xx unknown
- 1973-12-06 CH CH1714573A patent/CH605725A5/xx not_active IP Right Cessation
- 1973-12-06 DE DE2360893A patent/DE2360893A1/en not_active Withdrawn
- 1973-12-07 BE BE138669A patent/BE808398A/en unknown
- 1973-12-07 ES ES421274A patent/ES421274A1/en not_active Expired
- 1973-12-07 JP JP48137248A patent/JPS5024252A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
CH605725A5 (en) | 1978-10-13 |
BE808398A (en) | 1974-06-07 |
AU473283B2 (en) | 1976-06-17 |
LU68940A1 (en) | 1974-02-12 |
FR2209569B1 (en) | 1978-07-28 |
GB1402035A (en) | 1975-08-06 |
ZA738797B (en) | 1974-07-31 |
JPS5024252A (en) | 1975-03-15 |
IE38515B1 (en) | 1978-03-29 |
AU6279773A (en) | 1975-11-27 |
ES421274A1 (en) | 1976-04-16 |
DE2360893A1 (en) | 1974-06-12 |
CA1016940A (en) | 1977-09-06 |
FR2209569A1 (en) | 1974-07-05 |
NL7316508A (en) | 1974-06-11 |
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