IE36885L - Manufacture of benzodiazepines. - Google Patents
Manufacture of benzodiazepines.Info
- Publication number
- IE36885L IE36885L IE720927A IE92772A IE36885L IE 36885 L IE36885 L IE 36885L IE 720927 A IE720927 A IE 720927A IE 92772 A IE92772 A IE 92772A IE 36885 L IE36885 L IE 36885L
- Authority
- IE
- Ireland
- Prior art keywords
- benzodiazepines
- july
- manufacture
- formula
- gb1383647a
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/46—Oxygen atoms
- C07D213/50—Ketonic radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Sealing Material Composition (AREA)
- Paints Or Removers (AREA)
Abstract
1383647 Benzodiazepines ROCHE PRODUCTS Ltd 7 July 1972 [8 July 1971] 32107/71 Heading C2C Compounds of the general formula (R<SP>1</SP>=H, Cl, Br, I, NO 2 ; R<SP>2</SP>=phenyl, o-fluorophenyl, o-chlorophenyl), are prepared by reacting a compound of the formula (X=Cl, Br, I), with hexamethylenetetramine under weak acidic conditions in the presence of a water-containing hydroxylic solvent. Reference has been directed by the Comptroller to Specifications 972,968 1,039,372 and 1,332,697.
[GB1383647A]
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB3210771A GB1383647A (en) | 1971-07-08 | 1971-07-08 | Process for the manufacture of benzodiazepine derivatives |
Publications (2)
Publication Number | Publication Date |
---|---|
IE36885L true IE36885L (en) | 1973-01-08 |
IE36885B1 IE36885B1 (en) | 1977-03-16 |
Family
ID=10333351
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IE927/72A IE36885B1 (en) | 1971-07-08 | 1972-07-03 | A process for the manufacture of benzodiazepine derivatives |
Country Status (18)
Country | Link |
---|---|
AR (1) | AR192655A1 (en) |
AT (1) | AT334376B (en) |
AU (1) | AU463475B2 (en) |
BE (1) | BE785962A (en) |
CA (1) | CA963903A (en) |
CH (1) | CH570388A5 (en) |
DE (1) | DE2233482A1 (en) |
ES (1) | ES404627A1 (en) |
FR (1) | FR2144868B1 (en) |
GB (1) | GB1383647A (en) |
HU (1) | HU168636B (en) |
IE (1) | IE36885B1 (en) |
IL (1) | IL39847A (en) |
NL (1) | NL167426C (en) |
NO (1) | NO130189B (en) |
PH (1) | PH10943A (en) |
YU (1) | YU176972A (en) |
ZA (2) | ZA724577B (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH578544A5 (en) * | 1972-08-21 | 1976-08-13 | Hoffmann La Roche | |
JPS52106881A (en) * | 1976-03-05 | 1977-09-07 | Crc Ricerca Chim | Production of 1*44 benzodiazepine derivative |
FR2364207A1 (en) * | 1976-09-09 | 1978-04-07 | Scherico Ltd | Prepn. of 1,4-benzodiazepine cpds. - by reacting e.g. a 2-haloethyl-amino-benzophenone with hexa: methylene tetr:amine in presence of an ammonium salt and water alcohol solvent |
CN103804310A (en) * | 2013-11-19 | 2014-05-21 | 华中药业股份有限公司 | Method for preparing high-purity 7-chloro-5-phenyl-benzodiazepine-2-one |
-
0
- BE BE785962D patent/BE785962A/en unknown
-
1971
- 1971-07-08 GB GB3210771A patent/GB1383647A/en not_active Expired
-
1972
- 1972-06-21 CH CH932972A patent/CH570388A5/xx not_active IP Right Cessation
- 1972-07-03 IE IE927/72A patent/IE36885B1/en unknown
- 1972-07-03 PH PH13685A patent/PH10943A/en unknown
- 1972-07-04 ZA ZA724577A patent/ZA724577B/en unknown
- 1972-07-06 YU YU01769/72A patent/YU176972A/en unknown
- 1972-07-06 IL IL39847A patent/IL39847A/en unknown
- 1972-07-06 CA CA146,477A patent/CA963903A/en not_active Expired
- 1972-07-06 ZA ZA724639A patent/ZA724639B/en unknown
- 1972-07-07 AR AR242956A patent/AR192655A1/en active
- 1972-07-07 NL NL7209489.A patent/NL167426C/en not_active IP Right Cessation
- 1972-07-07 AT AT584672A patent/AT334376B/en active
- 1972-07-07 FR FR7224668A patent/FR2144868B1/fr not_active Expired
- 1972-07-07 DE DE2233482A patent/DE2233482A1/en not_active Ceased
- 1972-07-07 HU HUHO1497A patent/HU168636B/hu unknown
- 1972-07-07 NO NO02453/72*[A patent/NO130189B/no unknown
- 1972-07-07 AU AU44362/72A patent/AU463475B2/en not_active Expired
- 1972-07-07 ES ES404627A patent/ES404627A1/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
PH10943A (en) | 1977-10-05 |
ATA584672A (en) | 1976-05-15 |
AR192655A1 (en) | 1973-02-28 |
ES404627A1 (en) | 1975-06-16 |
BE785962A (en) | 1973-01-08 |
DE2233482A1 (en) | 1973-01-25 |
IL39847A0 (en) | 1972-09-28 |
NL167426C (en) | 1981-12-16 |
NL167426B (en) | 1981-07-16 |
IE36885B1 (en) | 1977-03-16 |
FR2144868A1 (en) | 1973-02-16 |
YU176972A (en) | 1979-07-10 |
NL7209489A (en) | 1973-01-10 |
AT334376B (en) | 1976-01-10 |
HU168636B (en) | 1976-06-28 |
GB1383647A (en) | 1974-02-12 |
ZA724577B (en) | 1973-03-28 |
IL39847A (en) | 1976-05-31 |
CA963903A (en) | 1975-03-04 |
AU4436272A (en) | 1974-01-10 |
CH570388A5 (en) | 1975-12-15 |
ZA724639B (en) | 1973-03-28 |
NO130189B (en) | 1974-07-22 |
FR2144868B1 (en) | 1976-05-14 |
AU463475B2 (en) | 1975-07-31 |
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