IE36607B1 - A propionamide derivative a method of making it and therapeutic compositions containing it - Google Patents
A propionamide derivative a method of making it and therapeutic compositions containing itInfo
- Publication number
- IE36607B1 IE36607B1 IE1058/72A IE105872A IE36607B1 IE 36607 B1 IE36607 B1 IE 36607B1 IE 1058/72 A IE1058/72 A IE 1058/72A IE 105872 A IE105872 A IE 105872A IE 36607 B1 IE36607 B1 IE 36607B1
- Authority
- IE
- Ireland
- Prior art keywords
- acid addition
- addition salts
- making
- compositions containing
- therapeutic compositions
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Pain & Pain Management (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
1374367 2 - Amino - 2<SP>1</SP>,6<SP>1</SP> - propionoxylidide ASTRA PHARMACEUTICAL PRODUCTS Inc 28 July 1972 [28 July 1971] 35481/72 Heading C2C The novel title compound and acid addition salts thereof are prepared by reacting a 2-halo- 2<SP>1</SP>,6<SP>1</SP>-propionoxylidide, wherein halo is Cl, Br or I, with ammonia, and, if desired, converting the resulting base into acid addition salts. Pharmaceutical compositions, suitable for oral or parenteral administration, contain the above novel compound or therapeutically acceptable acid addition salts thereof together with pharmaceutically acceptable carriers. The compound possesses antiarrhythmic properties.
[GB1374367A]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16703171A | 1971-07-28 | 1971-07-28 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE36607L IE36607L (en) | 1973-01-28 |
| IE36607B1 true IE36607B1 (en) | 1976-12-08 |
Family
ID=22605664
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE1058/72A IE36607B1 (en) | 1971-07-28 | 1972-07-27 | A propionamide derivative a method of making it and therapeutic compositions containing it |
Country Status (23)
| Country | Link |
|---|---|
| JP (1) | JPS565220B1 (en) |
| AR (1) | AR193748A1 (en) |
| AT (1) | AT317185B (en) |
| AU (1) | AU476000B2 (en) |
| BE (1) | BE786875A (en) |
| BR (1) | BR7205069D0 (en) |
| CA (1) | CA982148A (en) |
| CH (1) | CH574397A5 (en) |
| CS (1) | CS171171B2 (en) |
| DD (1) | DD101389A5 (en) |
| DK (1) | DK142843B (en) |
| ES (1) | ES404739A1 (en) |
| FI (1) | FI55492C (en) |
| FR (1) | FR2147277B1 (en) |
| GB (1) | GB1374367A (en) |
| HU (1) | HU163818B (en) |
| IE (1) | IE36607B1 (en) |
| NL (1) | NL176254C (en) |
| NO (1) | NO137500C (en) |
| PL (1) | PL84891B1 (en) |
| SE (1) | SE399702B (en) |
| SU (1) | SU441704A3 (en) |
| ZA (1) | ZA724512B (en) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS57182525U (en) * | 1981-05-15 | 1982-11-19 | ||
| JPH01128053U (en) * | 1988-02-24 | 1989-08-31 | ||
| JP2514855B2 (en) * | 1990-08-08 | 1996-07-10 | キッセイ薬品工業株式会社 | Acid addition salts of optically active alanine anilide derivatives |
| GB2267709A (en) * | 1992-06-11 | 1993-12-15 | Merck & Co Inc | Novel process for the preparation of alpha-aminoacylanilides |
| EP3485881B1 (en) | 2009-07-10 | 2024-03-13 | President and Fellows of Harvard College | Permanently charged sodium and calcium channel blockers as anti-inflammatory agents |
| DE102012210082A1 (en) * | 2012-06-15 | 2013-12-19 | Hilti Aktiengesellschaft | Machine tool and control method |
| JP6833811B2 (en) | 2015-08-03 | 2021-02-24 | プレジデント アンド フェローズ オブ ハーバード カレッジ | Charged ion channel blockers and how to use |
| US10828287B2 (en) | 2019-03-11 | 2020-11-10 | Nocion Therapeutics, Inc. | Charged ion channel blockers and methods for use |
| US10780083B1 (en) | 2019-03-11 | 2020-09-22 | Nocion Therapeutics, Inc. | Charged ion channel blockers and methods for use |
| WO2020185881A1 (en) | 2019-03-11 | 2020-09-17 | Nocion Therapeutics, Inc. | Charged ion channel blockers and methods for use |
| US11377422B2 (en) | 2019-03-11 | 2022-07-05 | Nocion Therapeutics, Inc. | Charged ion channel blockers and methods for use |
| CA3129089A1 (en) | 2019-03-11 | 2020-09-17 | Bridget Mccarthy Cole | Ester substituted ion channel blockers and methods for use |
| EP4054586A4 (en) | 2019-11-06 | 2023-11-22 | Nocion Therapeutics, Inc. | Charged ion channel blockers and methods for use |
| JP2023500891A (en) | 2019-11-06 | 2023-01-11 | ノシオン セラピューティクス，インコーポレイテッド | Charged ion channel blockers and methods of use |
| WO2021183639A1 (en) | 2020-03-11 | 2021-09-16 | Nocion Therapeutics, Inc. | Charged ion channel blockers and methods for use |
-
0
- BE BE786875D patent/BE786875A/en not_active IP Right Cessation
-
1972
- 1972-06-30 ZA ZA724512A patent/ZA724512B/en unknown
- 1972-07-04 CS CS4729A patent/CS171171B2/cs unknown
- 1972-07-04 SE SE7208768A patent/SE399702B/en unknown
- 1972-07-07 FI FI1945/72A patent/FI55492C/en active
- 1972-07-11 ES ES404739A patent/ES404739A1/en not_active Expired
- 1972-07-17 CA CA147,247A patent/CA982148A/en not_active Expired
- 1972-07-19 CH CH1080572A patent/CH574397A5/xx not_active IP Right Cessation
- 1972-07-20 SU SU1812965A patent/SU441704A3/en active
- 1972-07-20 GB GB3548172A patent/GB1374367A/en not_active Expired
- 1972-07-24 AU AU44886/72A patent/AU476000B2/en not_active Expired
- 1972-07-24 DK DK365272AA patent/DK142843B/en not_active IP Right Cessation
- 1972-07-25 AR AR243250A patent/AR193748A1/en active
- 1972-07-25 NO NO2662/72A patent/NO137500C/en unknown
- 1972-07-26 PL PL1972156947A patent/PL84891B1/en unknown
- 1972-07-27 FR FR7227161A patent/FR2147277B1/fr not_active Expired
- 1972-07-27 DD DD164729A patent/DD101389A5/xx unknown
- 1972-07-27 HU HUAA709A patent/HU163818B/hu unknown
- 1972-07-27 IE IE1058/72A patent/IE36607B1/en unknown
- 1972-07-28 NL NLAANVRAGE7210418,A patent/NL176254C/en not_active IP Right Cessation
- 1972-07-28 JP JP7518072A patent/JPS565220B1/ja active Pending
- 1972-07-28 AT AT650472A patent/AT317185B/en active
- 1972-07-28 BR BR5069/72A patent/BR7205069D0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NL176254C (en) | 1985-03-18 |
| HU163818B (en) | 1973-11-28 |
| CS171171B2 (en) | 1976-10-29 |
| ES404739A1 (en) | 1975-07-16 |
| DK142843C (en) | 1981-08-31 |
| ZA724512B (en) | 1973-08-29 |
| AR193748A1 (en) | 1973-05-22 |
| SU441704A3 (en) | 1974-08-30 |
| CA982148A (en) | 1976-01-20 |
| NL176254B (en) | 1984-10-16 |
| CH574397A5 (en) | 1976-04-15 |
| IE36607L (en) | 1973-01-28 |
| AT317185B (en) | 1974-08-12 |
| DE2235745B2 (en) | 1976-08-19 |
| DE2235745A1 (en) | 1973-02-22 |
| JPS565220B1 (en) | 1981-02-04 |
| FR2147277B1 (en) | 1976-04-16 |
| AU4488672A (en) | 1974-01-31 |
| FR2147277A1 (en) | 1973-03-09 |
| FI55492B (en) | 1979-04-30 |
| GB1374367A (en) | 1974-11-20 |
| AU476000B2 (en) | 1976-09-09 |
| SE399702B (en) | 1978-02-27 |
| FI55492C (en) | 1979-08-10 |
| DD101389A5 (en) | 1973-11-05 |
| BR7205069D0 (en) | 1973-07-17 |
| DK142843B (en) | 1981-02-09 |
| BE786875A (en) | 1973-01-29 |
| NO137500C (en) | 1978-03-08 |
| NL7210418A (en) | 1973-01-30 |
| NO137500B (en) | 1977-11-28 |
| PL84891B1 (en) | 1976-04-30 |
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