ID29452A - 4-okso-1,4-dihidro-3-quinolinkarboksamida sebagai agen-agen antivirus - Google Patents
4-okso-1,4-dihidro-3-quinolinkarboksamida sebagai agen-agen antivirusInfo
- Publication number
- ID29452A ID29452A IDW00200101463A ID20011463A ID29452A ID 29452 A ID29452 A ID 29452A ID W00200101463 A IDW00200101463 A ID W00200101463A ID 20011463 A ID20011463 A ID 20011463A ID 29452 A ID29452 A ID 29452A
- Authority
- ID
- Indonesia
- Prior art keywords
- quinolinkarboxamide
- okso
- dihydro
- substituted
- nr4r5
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11511399P | 1999-01-08 | 1999-01-08 | |
| US13839099P | 1999-06-09 | 1999-06-09 | |
| US14061499P | 1999-06-23 | 1999-06-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ID29452A true ID29452A (id) | 2001-08-30 |
Family
ID=27381602
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IDW00200101463A ID29452A (id) | 1999-01-08 | 1999-12-22 | 4-okso-1,4-dihidro-3-quinolinkarboksamida sebagai agen-agen antivirus |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US6248736B1 (es) |
| EP (1) | EP1140851B1 (es) |
| JP (1) | JP2002534417A (es) |
| KR (1) | KR20010101428A (es) |
| CN (1) | CN1132818C (es) |
| AT (1) | ATE275134T1 (es) |
| AU (1) | AU2158300A (es) |
| BR (1) | BR9916781A (es) |
| CA (1) | CA2353634A1 (es) |
| CO (1) | CO5150150A1 (es) |
| CZ (1) | CZ20012458A3 (es) |
| DE (1) | DE69919897T2 (es) |
| EA (1) | EA004043B1 (es) |
| ES (1) | ES2228162T3 (es) |
| HK (1) | HK1041879A1 (es) |
| HU (1) | HUP0105142A3 (es) |
| ID (1) | ID29452A (es) |
| IL (1) | IL144170A0 (es) |
| MY (1) | MY118904A (es) |
| NO (1) | NO320396B1 (es) |
| NZ (1) | NZ512823A (es) |
| PE (1) | PE20001337A1 (es) |
| PL (1) | PL348769A1 (es) |
| PT (1) | PT1140851E (es) |
| SK (1) | SK8312001A3 (es) |
| TR (1) | TR200101893T2 (es) |
| TW (1) | TW593281B (es) |
| WO (1) | WO2000040563A1 (es) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6559145B2 (en) | 2000-07-12 | 2003-05-06 | Pharmacia & Upjohn Company | Heterocycle carboxamides as antiviral agents |
| US6730682B2 (en) | 2000-07-12 | 2004-05-04 | Pharmacia & Upjohn Company | Heterocycle carboxamides as antiviral agents |
| US6562822B2 (en) | 2000-07-12 | 2003-05-13 | Pharmacia & Upjohn Company | Heterocyle carboxamides as antiviral agents |
| US6682892B2 (en) * | 2000-07-13 | 2004-01-27 | Pharmacia & Upjohn Company | Method for treating herpes viruses |
| US20100074949A1 (en) | 2008-08-13 | 2010-03-25 | William Rowe | Pharmaceutical composition and administration thereof |
| EP1363887A1 (en) * | 2001-03-01 | 2003-11-26 | PHARMACIA & UPJOHN COMPANY | Substituted quinolinecarboxamides as antiviral agents |
| WO2003020728A1 (en) | 2001-08-30 | 2003-03-13 | Pharmacia & Upjohn Company | 4-THIOXO-4,7-DIHYDRO-THIENO[2,3-b]PYRIDINE-5-CARBOTHIOAMIDES AS ANTIVIRAL AGENTS |
| AR038118A1 (es) * | 2002-01-14 | 2004-12-29 | Upjohn Co | Compuestos derivados de la bencinamida del acido 7-oxo-4,7-dihidrotien[2,3-b[piridin-6-carboxilico 3-sustituido que son utiles como antivirales |
| AR038294A1 (es) | 2002-01-14 | 2005-01-12 | Upjohn Co | Oxotieno(3,2-b)piridincarboxamidas como agentes antivirales |
| AR038117A1 (es) | 2002-01-14 | 2004-12-29 | Upjohn Co | Agentes antivirales derivados de la 4- oxo-4,7 -dihidrofuro [2,3-b]piridin-5-carboxamida |
| WO2004019933A1 (en) * | 2002-08-30 | 2004-03-11 | Pharmacia & Upjohn Company | Method of preventing or treating atherosclerosis or restenosis |
| US20040186131A1 (en) * | 2002-08-30 | 2004-09-23 | Wathen Michael W | Method of preventing or treating atherosclerosis or restenosis |
| CN100375742C (zh) * | 2002-11-20 | 2008-03-19 | 日本烟草产业株式会社 | 4-氧代喹啉化合物及其用途 |
| EP3406596A1 (en) | 2002-11-20 | 2018-11-28 | Japan Tobacco Inc. | 4-oxoquinoline compound and use thereof as hiv integrase inhibitor |
| MXPA06000675A (es) | 2003-07-24 | 2006-04-19 | Astellas Pharma Inc | Derivado de quinolona o sal del mismo. |
| US7531554B2 (en) | 2004-05-20 | 2009-05-12 | Japan Tobacco Inc. | 4-oxoquinoline compound and use thereof as HIV integrase inhibitor |
| MY134672A (en) * | 2004-05-20 | 2007-12-31 | Japan Tobacco Inc | Stable crystal of 4-oxoquinoline compound |
| WO2005112930A1 (en) * | 2004-05-21 | 2005-12-01 | Japan Tobacco Inc. | Combinations comprising a 4-isoquinolone derivative and anti-hiv agents |
| RS53895B1 (en) | 2004-06-24 | 2015-08-31 | Vertex Pharmaceuticals Incorporated | ATP-BINDING CASSETTE TRANSPORT MODULATORS |
| US20070032522A1 (en) * | 2005-07-01 | 2007-02-08 | Kumar Dange V | Antiviral agents |
| PL3219705T3 (pl) | 2005-12-28 | 2020-08-10 | Vertex Pharmaceuticals Incorporated | Kompozycje farmaceutyczne amorficznych postaci n-[2,4-bis(1,1-dimetyloetylo)-5-hydroksyfenylo]-1,4-dihydro-4-oksochinolino-3-karboksyamidu |
| US20090018162A1 (en) * | 2006-02-01 | 2009-01-15 | Yuji Matsuzaki | Use of 6-(3-chloro-2-fluorobenzyl)-1-[(2s)-1-hydroxy-3-methylbutan-2-yl]-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid or salt thereof for treating retrovirus infection |
| AU2007223260C1 (en) * | 2006-03-06 | 2011-02-03 | Japan Tobacco Inc. | Method for producing 4-oxoquinoline compound |
| DE102008036099B4 (de) | 2008-08-04 | 2014-02-13 | Steag Power Saar Gmbh | Entstickungsanlage |
| SI2821400T1 (en) | 2009-03-20 | 2018-02-28 | Vertex Pharmaceuticals Incorporated | A process for the manufacture of a transmembrane conductivity regulator in cystic fibrosis |
| WO2011004389A2 (en) | 2009-06-18 | 2011-01-13 | Matrix Laboratories Ltd | An improved process for the preparation of elvitegravir |
| NZ604745A (en) * | 2010-08-27 | 2015-01-30 | Gruenenthal Chemie | Substituted 2-oxy-quinoline-3-carboxamides as kcnq2/3 modulators |
| EP2819670A1 (en) | 2012-02-27 | 2015-01-07 | Vertex Pharmaceuticals Incorporated | Pharmaceutical composition and administration thereof |
| BR112015008515A2 (pt) | 2012-10-16 | 2017-07-04 | Janssen Pharmaceutica Nv | moduladores de ror t de quinolinila ligada à heteroarila |
| EP2909193B1 (en) | 2012-10-16 | 2017-04-19 | Janssen Pharmaceutica NV | Phenyl linked quinolinyl modulators of ror-gamma-t |
| WO2014062658A1 (en) | 2012-10-16 | 2014-04-24 | Janssen Pharmaceutica Nv | Methylene linked quinolinyl modulators of ror-gamma-t |
| US9403816B2 (en) | 2013-10-15 | 2016-08-02 | Janssen Pharmaceutica Nv | Phenyl linked quinolinyl modulators of RORγt |
| US9221804B2 (en) | 2013-10-15 | 2015-12-29 | Janssen Pharmaceutica Nv | Secondary alcohol quinolinyl modulators of RORγt |
| US10555941B2 (en) | 2013-10-15 | 2020-02-11 | Janssen Pharmaceutica Nv | Alkyl linked quinolinyl modulators of RORγt |
| KR20160068956A (ko) | 2013-10-15 | 2016-06-15 | 얀센 파마슈티카 엔.브이. | RORyT의 퀴놀리닐 조절제 |
| US9328095B2 (en) | 2013-10-15 | 2016-05-03 | Janssen Pharmaceutica Nv | Heteroaryl linked quinolinyl modulators of RORgammat |
| US9284308B2 (en) | 2013-10-15 | 2016-03-15 | Janssen Pharmaceutica Nv | Methylene linked quinolinyl modulators of RORγt |
| KR20160070133A (ko) | 2013-10-15 | 2016-06-17 | 얀센 파마슈티카 엔.브이. | RORyt의 알킬 결합 퀴놀리닐 조절제 |
| JP6746569B2 (ja) | 2014-10-07 | 2020-08-26 | バーテックス ファーマシューティカルズ インコーポレイテッドＶｅｒｔｅｘ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃｏｒｐｏｒａｔｅｄ | 嚢胞性線維症膜貫通コンダクタンス制御因子のモジュレーターの共結晶 |
| AU2019339777B2 (en) | 2018-09-12 | 2022-09-01 | Novartis Ag | Antiviral pyridopyrazinedione compounds |
| KR20220070005A (ko) | 2019-09-26 | 2022-05-27 | 노파르티스 아게 | 항바이러스성 피라졸로피리디논 화합물 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2593810B1 (fr) * | 1986-01-24 | 1988-04-22 | Sanofi Sa | Derives de la quinoleine, leur procede de preparation, leur application a titre de medicaments et les compositions les renfermant |
| US4786644A (en) * | 1987-11-27 | 1988-11-22 | Hoechst-Roussel Pharmaceuticals Inc. | 1-aryl-3-quinolinecarboxamide |
| US4959363A (en) * | 1989-06-23 | 1990-09-25 | Sterling Drug Inc. | Quinolonecarboxamide compounds, their preparation and use as antivirals. |
| US5175151A (en) | 1990-09-07 | 1992-12-29 | Schering Corporation | Antiviral compounds and antihypertensive compounds |
| EP0550464A1 (en) * | 1990-09-07 | 1993-07-14 | Schering Corporation | Antiviral compounds and antihypertensive compounds |
| DE69115692T2 (de) | 1991-09-10 | 1996-08-01 | Agfa Gevaert Nv | Thermisch übertragbare fluoreszierende Verbindungen |
| WO1997004779A1 (en) * | 1995-08-02 | 1997-02-13 | Chiroscience Limited | Quinolones and their therapeutic use |
| EP0876349B1 (en) | 1995-10-19 | 2002-09-11 | Takeda Chemical Industries, Ltd. | Quinoline derivatives as gnrh antagonists |
| DE69736812T2 (de) | 1996-11-27 | 2007-08-09 | Bristol-Myers Squibb Pharma Co. | Neue integrin rezeptor antagonisten |
| CA2309882A1 (en) | 1997-12-22 | 1999-07-01 | Pharmacia & Upjohn Company | 4-hydroxyquinoline-3-carboxamides and hydrazides as antiviral agents |
-
1999
- 1999-12-17 US US09/465,670 patent/US6248736B1/en not_active Expired - Fee Related
- 1999-12-22 EA EA200100755A patent/EA004043B1/ru not_active IP Right Cessation
- 1999-12-22 SK SK831-2001A patent/SK8312001A3/sk unknown
- 1999-12-22 DE DE69919897T patent/DE69919897T2/de not_active Expired - Fee Related
- 1999-12-22 AT AT99965907T patent/ATE275134T1/de not_active IP Right Cessation
- 1999-12-22 PL PL99348769A patent/PL348769A1/xx unknown
- 1999-12-22 AU AU21583/00A patent/AU2158300A/en not_active Abandoned
- 1999-12-22 EP EP99965907A patent/EP1140851B1/en not_active Expired - Lifetime
- 1999-12-22 HU HU0105142A patent/HUP0105142A3/hu unknown
- 1999-12-22 PT PT99965907T patent/PT1140851E/pt unknown
- 1999-12-22 CA CA002353634A patent/CA2353634A1/en not_active Abandoned
- 1999-12-22 TR TR2001/01893T patent/TR200101893T2/xx unknown
- 1999-12-22 KR KR1020017008641A patent/KR20010101428A/ko not_active Application Discontinuation
- 1999-12-22 CZ CZ20012458A patent/CZ20012458A3/cs unknown
- 1999-12-22 CN CN998151602A patent/CN1132818C/zh not_active Expired - Fee Related
- 1999-12-22 ES ES99965907T patent/ES2228162T3/es not_active Expired - Lifetime
- 1999-12-22 ID IDW00200101463A patent/ID29452A/id unknown
- 1999-12-22 JP JP2000592271A patent/JP2002534417A/ja active Pending
- 1999-12-22 IL IL14417099A patent/IL144170A0/xx unknown
- 1999-12-22 NZ NZ512823A patent/NZ512823A/en unknown
- 1999-12-22 BR BR9916781-6A patent/BR9916781A/pt not_active Application Discontinuation
- 1999-12-22 WO PCT/US1999/027959 patent/WO2000040563A1/en active Search and Examination
- 1999-12-24 MY MYPI99005719A patent/MY118904A/en unknown
- 1999-12-28 PE PE1999001326A patent/PE20001337A1/es not_active Application Discontinuation
- 1999-12-29 CO CO99081336A patent/CO5150150A1/es unknown
-
2000
- 2000-01-07 TW TW089100222A patent/TW593281B/zh not_active IP Right Cessation
-
2001
- 2001-07-06 NO NO20013379A patent/NO320396B1/no unknown
-
2002
- 2002-05-07 HK HK02103436A patent/HK1041879A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| KR20010101428A (ko) | 2001-11-14 |
| TW593281B (en) | 2004-06-21 |
| DE69919897T2 (de) | 2005-09-08 |
| CZ20012458A3 (cs) | 2001-12-12 |
| EA004043B1 (ru) | 2003-12-25 |
| PE20001337A1 (es) | 2000-11-23 |
| EA200100755A1 (ru) | 2001-12-24 |
| ES2228162T3 (es) | 2005-04-01 |
| IL144170A0 (en) | 2002-05-23 |
| NO20013379D0 (no) | 2001-07-06 |
| US6248736B1 (en) | 2001-06-19 |
| ATE275134T1 (de) | 2004-09-15 |
| CA2353634A1 (en) | 2000-07-13 |
| WO2000040563A1 (en) | 2000-07-13 |
| JP2002534417A (ja) | 2002-10-15 |
| EP1140851B1 (en) | 2004-09-01 |
| PT1140851E (pt) | 2004-12-31 |
| DE69919897D1 (en) | 2004-10-07 |
| CN1332729A (zh) | 2002-01-23 |
| TR200101893T2 (tr) | 2001-11-21 |
| CN1132818C (zh) | 2003-12-31 |
| AU2158300A (en) | 2000-07-24 |
| CO5150150A1 (es) | 2002-04-29 |
| NO320396B1 (no) | 2005-11-28 |
| NZ512823A (en) | 2003-10-31 |
| EP1140851A1 (en) | 2001-10-10 |
| NO20013379L (no) | 2001-07-06 |
| MY118904A (en) | 2005-02-28 |
| HUP0105142A2 (hu) | 2002-04-29 |
| PL348769A1 (en) | 2002-06-17 |
| HK1041879A1 (en) | 2002-07-26 |
| HUP0105142A3 (en) | 2002-05-28 |
| SK8312001A3 (en) | 2001-12-03 |
| BR9916781A (pt) | 2001-12-04 |
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