HUT61017A - Process for producing 4-/3-(4-oxothiazolidinyl)/-butinylamine derivatives and pharmaceutical compositions comprising same as active ingredient - Google Patents

Process for producing 4-/3-(4-oxothiazolidinyl)/-butinylamine derivatives and pharmaceutical compositions comprising same as active ingredient

Info

Publication number: HUT61017A
Authority: HU; Hungary
Prior art keywords: butinylamine; oxothiazolidinyl; derivatives; producing; active ingredient
Prior art date: 1990-04-16

Application number

HU911239A

Other languages

English (en)

Other versions

HU911239D0 (en

Inventor

Nicholas Joseph Hrib

Original Assignee

Hoechst Roussel Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-04-16

Filing date

1991-04-15

Publication date

1992-11-30

1991-04-15 Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma

1991-10-28 Publication of HU911239D0 publication Critical patent/HU911239D0/hu

1992-11-30 Publication of HUT61017A publication Critical patent/HUT61017A/hu

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/14—Oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Pain & Pain Management (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Cardiology (AREA)
Rheumatology (AREA)
Heart & Thoracic Surgery (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Thiazole And Isothizaole Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)

HU911239A 1990-04-16 1991-04-15 Process for producing 4-/3-(4-oxothiazolidinyl)/-butinylamine derivatives and pharmaceutical compositions comprising same as active ingredient HUT61017A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/509,280 US5034392A (en)	1990-04-16	1990-04-16	4-(3-(4-oxothiazolidinyl)butynylamines

Publications (2)

Publication Number	Publication Date
HU911239D0 HU911239D0 (en)	1991-10-28
HUT61017A true HUT61017A (en)	1992-11-30

Family

ID=24025983

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HU911239A HUT61017A (en)	1990-04-16	1991-04-15	Process for producing 4-/3-(4-oxothiazolidinyl)/-butinylamine derivatives and pharmaceutical compositions comprising same as active ingredient

Country Status (26)

Country	Link
US (1)	US5034392A (hu)
EP (1)	EP0452850B1 (hu)
JP (1)	JPH07119223B2 (hu)
KR (1)	KR0163598B1 (hu)
AR (1)	AR248402A1 (hu)
AT (1)	ATE163010T1 (hu)
AU (1)	AU636972B2 (hu)
BG (1)	BG60066A3 (hu)
CA (1)	CA2040489C (hu)
CZ (1)	CZ284447B6 (hu)
DE (1)	DE69128845T2 (hu)
DK (1)	DK0452850T3 (hu)
ES (1)	ES2112844T3 (hu)
FI (1)	FI94755C (hu)
GR (1)	GR3026319T3 (hu)
HU (1)	HUT61017A (hu)
IE (1)	IE911257A1 (hu)
IL (1)	IL97852A (hu)
MX (1)	MX25359A (hu)
NO (1)	NO300134B1 (hu)
NZ (1)	NZ237811A (hu)
PL (1)	PL165488B1 (hu)
PT (1)	PT97371B (hu)
RO (1)	RO108683B1 (hu)
RU (1)	RU2001914C1 (hu)
ZA (1)	ZA912783B (hu)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5273977A (en) *	1990-11-05	1993-12-28	Warner-Lambert Company	Substituted tetrahydropyridines and hydroxypiperidines as central nervous system agents
US5147881A (en) *	1990-11-14	1992-09-15	Pfizer Inc	4-(1,2-benzisoxazolyl)piperidine antipsychotic agents
US5194436A (en) *	1991-01-10	1993-03-16	Hoechst-Roussel Pharmaceuticals Inc.	1-piperazinyl-2-butenes and -2-butynes
US5130315A (en) *	1991-01-10	1992-07-14	Raymond R. Wittekind	1-piperazinyl-2-butenes and -2-butynes

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3354178A (en) *	1965-04-09	1967-11-21	Sterling Drug Inc	Nu-(4-amino-2-butynyl)-nu-alkylcarboxamides
ES2052675T3 (es) *	1987-11-20	1994-07-16	Hoechst Roussel Pharma	3-(4-piperazinil-sustituido en 1)butil)-4-tiazolidinonas, un procedimiento para su preparacion y su uso como medicamentos.

1990
- 1990-04-16 US US07/509,280 patent/US5034392A/en not_active Expired - Lifetime
1991
- 1991-04-09 BG BG94208A patent/BG60066A3/xx unknown
- 1991-04-12 FI FI911783A patent/FI94755C/fi not_active IP Right Cessation
- 1991-04-12 RO RO147316A patent/RO108683B1/ro unknown
- 1991-04-12 NZ NZ237811A patent/NZ237811A/en unknown
- 1991-04-12 AR AR91319454A patent/AR248402A1/es active
- 1991-04-15 HU HU911239A patent/HUT61017A/hu unknown
- 1991-04-15 DK DK91105972T patent/DK0452850T3/da active
- 1991-04-15 JP JP3109867A patent/JPH07119223B2/ja not_active Expired - Fee Related
- 1991-04-15 IL IL9785291A patent/IL97852A/en not_active IP Right Cessation
- 1991-04-15 ZA ZA912783A patent/ZA912783B/xx unknown
- 1991-04-15 CA CA002040489A patent/CA2040489C/en not_active Expired - Fee Related
- 1991-04-15 ES ES91105972T patent/ES2112844T3/es not_active Expired - Lifetime
- 1991-04-15 CZ CS911065A patent/CZ284447B6/cs not_active IP Right Cessation
- 1991-04-15 DE DE69128845T patent/DE69128845T2/de not_active Expired - Fee Related
- 1991-04-15 PT PT97371A patent/PT97371B/pt not_active IP Right Cessation
- 1991-04-15 KR KR1019910005987A patent/KR0163598B1/ko not_active IP Right Cessation
- 1991-04-15 IE IE125791A patent/IE911257A1/en not_active IP Right Cessation
- 1991-04-15 RU SU914895050A patent/RU2001914C1/ru active
- 1991-04-15 MX MX25359A patent/MX25359A/es unknown
- 1991-04-15 AT AT91105972T patent/ATE163010T1/de not_active IP Right Cessation
- 1991-04-15 PL PL91289892A patent/PL165488B1/pl unknown
- 1991-04-15 AU AU75028/91A patent/AU636972B2/en not_active Ceased
- 1991-04-15 NO NO911465A patent/NO300134B1/no unknown
- 1991-04-15 EP EP91105972A patent/EP0452850B1/en not_active Expired - Lifetime
1998
- 1998-03-11 GR GR980400510T patent/GR3026319T3/el unknown

Also Published As

Publication number	Publication date
FI94755C (fi)	1995-10-25
NO300134B1 (no)	1997-04-14
GR3026319T3 (en)	1998-06-30
EP0452850A1 (en)	1991-10-23
CZ284447B6 (cs)	1998-11-11
AR248402A1 (es)	1995-08-18
CS9101065A2 (en)	1991-11-12
IE911257A1 (en)	1991-10-23
NO911465D0 (no)	1991-04-15
HU911239D0 (en)	1991-10-28
JPH07119223B2 (ja)	1995-12-20
AU7502891A (en)	1991-10-17
FI911783A (fi)	1991-10-17
AU636972B2 (en)	1993-05-13
MX25359A (es)	1994-05-31
CA2040489A1 (en)	1991-10-17
RU2001914C1 (ru)	1993-10-30
BG60066A3 (en)	1993-09-15
JPH04234879A (ja)	1992-08-24
FI94755B (fi)	1995-07-14
NO911465L (no)	1991-10-17
KR910018367A (ko)	1991-11-30
DK0452850T3 (da)	1998-09-23
ATE163010T1 (de)	1998-02-15
FI911783A0 (fi)	1991-04-12
DE69128845T2 (de)	1998-07-09
EP0452850B1 (en)	1998-02-04
CA2040489C (en)	2003-06-10
KR0163598B1 (ko)	1998-12-01
PL165488B1 (pl)	1994-12-30
IL97852A0 (en)	1992-06-21
US5034392A (en)	1991-07-23
ES2112844T3 (es)	1998-04-16
IL97852A (en)	1994-11-28
NZ237811A (en)	1993-12-23
ZA912783B (en)	1991-12-24
DE69128845D1 (de)	1998-03-12
RO108683B1 (ro)	1994-07-29
PT97371B (pt)	1998-08-31
PT97371A (pt)	1992-01-31
PL289892A1 (en)	1992-07-27

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Legal Events

Date	Code	Title	Description
1996-07-29	DGB9	Succession in title of applicant	Owner name: HOECHST MARION ROUSSEL, INCORPORATED, US
2001-01-29	DFD9	Temporary protection cancelled due to non-payment of fee