HUT49564A - Process for producing salt-type compounds and pharmaceutical compositions containing them - Google Patents

Process for producing salt-type compounds and pharmaceutical compositions containing them

Info

Publication number
HUT49564A
HUT49564A HU881131A HU113188A HUT49564A HU T49564 A HUT49564 A HU T49564A HU 881131 A HU881131 A HU 881131A HU 113188 A HU113188 A HU 113188A HU T49564 A HUT49564 A HU T49564A
Authority
HU
Hungary
Prior art keywords
pharmaceutical compositions
compositions containing
type compounds
producing salt
salt
Prior art date
Application number
HU881131A
Other languages
Hungarian (hu)
Other versions
HU199775B (en
Inventor
Nagy Peter Literati
Jenoe Szilbereky
Gyoengyver Soos
Alan Pinter
Maria Boross
Istvan Racz
Miklos Koller
Gabor Nemeth
Original Assignee
Nagy Peter Literati
Jenoe Szilbereky
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nagy Peter Literati, Jenoe Szilbereky filed Critical Nagy Peter Literati
Priority to HU881131A priority Critical patent/HU199775B/en
Priority to CH820/89A priority patent/CH678851A5/de
Priority to AT0050989A priority patent/AT398073B/en
Priority to IT8919705A priority patent/IT1229563B/en
Priority to LU87470A priority patent/LU87470A1/en
Priority to BE8900253A priority patent/BE1003663A3/en
Priority to FI891144A priority patent/FI93949C/en
Priority to SE8900827A priority patent/SE508603C2/en
Priority to FR898903084A priority patent/FR2628419B1/en
Priority to KR1019890002919A priority patent/KR0140993B1/en
Priority to ES8900861A priority patent/ES2010439A6/en
Priority to JP1055241A priority patent/JP2751068B2/en
Priority to NL8900573A priority patent/NL8900573A/en
Priority to CA000593269A priority patent/CA1339147C/en
Priority to GB8905384A priority patent/GB2216522B/en
Priority to DE3907688A priority patent/DE3907688C2/en
Publication of HUT49564A publication Critical patent/HUT49564A/en
Publication of HU199775B publication Critical patent/HU199775B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/08—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to hydrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/24—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one carboxyl group bound to the carbon skeleton, e.g. aspartic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/26—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one amino group bound to the carbon skeleton, e.g. lysine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C07C229/36—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings with at least one amino group and one carboxyl group bound to the same carbon atom of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C237/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/14—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C07C57/03—Monocarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • AIDS & HIV (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
HU881131A 1988-03-09 1988-03-09 Process for production of formed by fatty acids salts of amin acids and medical compositions containing them HU199775B (en)

Priority Applications (16)

Application Number Priority Date Filing Date Title
HU881131A HU199775B (en) 1988-03-09 1988-03-09 Process for production of formed by fatty acids salts of amin acids and medical compositions containing them
CH820/89A CH678851A5 (en) 1988-03-09 1989-03-06
AT0050989A AT398073B (en) 1988-03-09 1989-03-07 ANTIVIRAL AND IMMUNOTIMULATING NEW SALTS, AND METHOD FOR THE PRODUCTION AND USE THEREOF
IT8919705A IT1229563B (en) 1988-03-09 1989-03-09 SALT TYPE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCEDURE FOR THEIR PREPARATION.
LU87470A LU87470A1 (en) 1988-03-09 1989-03-09 NOVEL ANTIVIRAL SALTS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING THE SAME
BE8900253A BE1003663A3 (en) 1988-03-09 1989-03-09 NEW ANTIVIRAL SALTS, pharmaceutical compositions containing AND METHOD FOR PREPARING.
FI891144A FI93949C (en) 1988-03-09 1989-03-09 Process for the preparation of novel therapeutically useful salt compounds
SE8900827A SE508603C2 (en) 1988-03-09 1989-03-09 New salt-type compounds, pharmaceutical compositions containing them and process for their preparation
FR898903084A FR2628419B1 (en) 1988-03-09 1989-03-09 NOVEL ANTIVIRAL SALTS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING THE SAME
KR1019890002919A KR0140993B1 (en) 1988-03-09 1989-03-09 Aminoacid salts of long chain unsaturated carboxylic acids
ES8900861A ES2010439A6 (en) 1988-03-09 1989-03-09 Aminoacid salts of long chain unsaturated carboxylic acids
JP1055241A JP2751068B2 (en) 1988-03-09 1989-03-09 Antiviral agent and method for producing the same
NL8900573A NL8900573A (en) 1988-03-09 1989-03-09 NEW SALT TYPE COMPOUNDS, PHARMACEUTICAL PREPARATIONS WITH SUCH COMPOUNDS IN IT AND METHOD FOR THE PREPARATION THEREOF.
CA000593269A CA1339147C (en) 1988-03-09 1989-03-09 Salt-type compounds, pharmaceutical compositions containing them and process for preparing same
GB8905384A GB2216522B (en) 1988-03-09 1989-03-09 Amino acid salts of long chain unsaturated fatty acid
DE3907688A DE3907688C2 (en) 1988-03-09 1989-03-09 Salts of unsaturated fatty acids with amino acids, process for their preparation and the use of the former and other such salts

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU881131A HU199775B (en) 1988-03-09 1988-03-09 Process for production of formed by fatty acids salts of amin acids and medical compositions containing them

Publications (2)

Publication Number Publication Date
HUT49564A true HUT49564A (en) 1989-10-30
HU199775B HU199775B (en) 1990-03-28

Family

ID=10952971

Family Applications (1)

Application Number Title Priority Date Filing Date
HU881131A HU199775B (en) 1988-03-09 1988-03-09 Process for production of formed by fatty acids salts of amin acids and medical compositions containing them

Country Status (16)

Country Link
JP (1) JP2751068B2 (en)
KR (1) KR0140993B1 (en)
AT (1) AT398073B (en)
BE (1) BE1003663A3 (en)
CA (1) CA1339147C (en)
CH (1) CH678851A5 (en)
DE (1) DE3907688C2 (en)
ES (1) ES2010439A6 (en)
FI (1) FI93949C (en)
FR (1) FR2628419B1 (en)
GB (1) GB2216522B (en)
HU (1) HU199775B (en)
IT (1) IT1229563B (en)
LU (1) LU87470A1 (en)
NL (1) NL8900573A (en)
SE (1) SE508603C2 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04279523A (en) * 1991-01-11 1992-10-05 Nisshin Flour Milling Co Ltd Fatty oil processed product for stimulating immunity
US5604258A (en) * 1991-06-24 1997-02-18 Women's And Children's Hospital Adelaide Methods for treating malaria and other diseases
US5767156A (en) * 1993-10-06 1998-06-16 Peptide Technology Limited Polyunsaturated fatty acids and uses thereof
NL9401743A (en) * 1994-10-20 1996-06-03 Prospa Bv Salts of amino alcohols and pharmaceutical formulations containing them.
AUPM906594A0 (en) * 1994-10-26 1994-11-17 Peptide Technology Limited Synthetic polyunsaturated fatty acid analogues
US5639858A (en) * 1995-03-22 1997-06-17 Tularik, Inc. Human signal transducer and binding assays
HU227588B1 (en) 2004-12-03 2011-09-28 Sinnex Mueszaki Fejlesztoe Es Tanacsado Kft Antiviral and immunostimulant pharmaceutical composition containing polyunsaturated fatty acid esters
KR101496373B1 (en) * 2005-12-30 2015-02-26 레반스 테라퓨틱스, 아이엔씨. Arginine heteromers for topical administration
AU2015371376B2 (en) 2014-12-23 2020-04-23 Evonik Operations Gmbh Process for increasing the stability of a composition comprising polyunsaturated omega-3 fatty acids
EP3248467A1 (en) * 2016-05-25 2017-11-29 Evonik Technochemie GmbH Method for preparing a composition containing omega-3-fatty acid-l-lysin-salts
AU2018317802B2 (en) 2017-08-15 2024-04-04 Evonik Operations Gmbh Tablets with high active ingredient content of omega-3 fatty acid amino acid salts
WO2021151201A1 (en) * 2020-01-30 2021-08-05 Silicycle Inc. Process for manufacturing solid neutral amino acid salts of polyunsaturated fatty acids

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4887011A (en) * 1972-02-04 1973-11-16
US4513008A (en) * 1982-07-30 1985-04-23 The Vinoxen Company, Inc. Virucidal compositions and therapy
GB8327911D0 (en) * 1983-10-19 1983-11-23 Ciba Geigy Ag Salts as corrosion inhibitors
US4537772A (en) * 1984-05-02 1985-08-27 Merck & Co., Inc. Enhancing absorption of drugs from gastrointestinal tract using acylcarnitines
FR2587900B1 (en) * 1985-10-01 1988-10-07 Morelle Jean BASIC FATTY-AMINO ACID ASSOCIATIONS WITH EMOLLIENT, EMULSIFIING AND ANTIOXIDANT PROPERTIES FOR COSMETICS, DERMATOLOGY AND FOOD
JPS63230632A (en) * 1987-03-20 1988-09-27 Nippon Oil & Fats Co Ltd Agent for stimulating lipoxygenase metabolism
DE3726299A1 (en) * 1987-06-26 1989-02-23 Dietl Hans Fat emulsion for intravenous use

Also Published As

Publication number Publication date
FR2628419A1 (en) 1989-09-15
SE8900827L (en) 1989-09-10
GB2216522A (en) 1989-10-11
FR2628419B1 (en) 1992-02-14
LU87470A1 (en) 1990-10-02
ATA50989A (en) 1994-01-15
KR890014451A (en) 1989-10-23
DE3907688C2 (en) 1996-09-05
FI93949C (en) 1995-06-26
SE8900827D0 (en) 1989-03-09
JPH024746A (en) 1990-01-09
NL8900573A (en) 1989-10-02
BE1003663A3 (en) 1992-05-19
FI891144A0 (en) 1989-03-09
GB2216522B (en) 1992-01-02
HU199775B (en) 1990-03-28
FI891144A (en) 1989-09-10
AT398073B (en) 1994-09-26
GB8905384D0 (en) 1989-04-19
CH678851A5 (en) 1991-11-15
FI93949B (en) 1995-03-15
ES2010439A6 (en) 1989-11-01
DE3907688A1 (en) 1989-09-21
IT8919705A0 (en) 1989-03-09
JP2751068B2 (en) 1998-05-18
CA1339147C (en) 1997-07-29
KR0140993B1 (en) 1998-07-01
SE508603C2 (en) 1998-10-19
IT1229563B (en) 1991-09-04

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Legal Events

Date Code Title Description
HU90 Patent valid on 900628
HMM4 Cancellation of final prot. due to non-payment of fee
HRH9 Withdrawal of annulment decision
HPC4 Succession in title of patentee

Owner name: BIOREX KUTATO-FEJLESZTOE KFT., HU

HPC4 Succession in title of patentee

Owner name: BIOREX KUTATO ES FEJLESZTOE RT., HU

HPC4 Succession in title of patentee

Owner name: HERBARIA GYOGYNOVENYFELDOLGOZO ES KERESKEDELMI RES

HC9A Change of name, address

Owner name: HERBARIA GYOGYNOEVENYFELDOLGOZO ES KERESKEDELM, HU

Free format text: FORMER OWNER(S): BIOREX KUTATO ES FEJLESZTOE KFT, HU; BIOREX KUTATO ES FEJLESZTOE RT., HU; BIOREX KUTATO ES FEJLESZTOE RT., HU; HERBARIA GYOGYNOEVENYFELDOLGOZO ES KERESKEDELMI RESZVENYTARSASAG, HU