HUP0402036A2 - Protein tirozin-kináz inhibitorokkal bevont vagy impregnált vaszkuláris stent vagy graft és eljárás alkalmazására - Google Patents

Protein tirozin-kináz inhibitorokkal bevont vagy impregnált vaszkuláris stent vagy graft és eljárás alkalmazására

Info

Publication number
HUP0402036A2
HUP0402036A2 HU0402036A HUP0402036A HUP0402036A2 HU P0402036 A2 HUP0402036 A2 HU P0402036A2 HU 0402036 A HU0402036 A HU 0402036A HU P0402036 A HUP0402036 A HU P0402036A HU P0402036 A2 HUP0402036 A2 HU P0402036A2
Authority
HU
Hungary
Prior art keywords
tyrosine kinase
protein tyrosine
impregnated
vascular
same
Prior art date
Application number
HU0402036A
Other languages
English (en)
Inventor
Matthew R. Wolff
Scott William Stoker
Michael Orrin Griffin
Original Assignee
Wisconsin Alumni Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Research Foundation filed Critical Wisconsin Alumni Research Foundation
Publication of HUP0402036A2 publication Critical patent/HUP0402036A2/hu
Publication of HUP0402036A3 publication Critical patent/HUP0402036A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06—Blood vessels
    • A61F2/07—Stent-grafts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Abstract

A találmány tárgya véredények stentelésére szolgáló eszköz, példáulegy kardiovaszkuláris stent, autológ véna/artéria graft, protetikusvéna/artéria graft, érkatéter vagy érsönt, mely egy protein tirozin-kináz inhibitorral van bevonva, adszorbeálva, impregnálva, vagy azkovalensen vagy ionosan kötődik hozzá. A protein tirozin-kinázinhibitor meggátolja az ér simaizomsejtek proliferációját a véredényegy olyan területén, mely közvetlenül szomszédos a fenti eszközzelés/vagy annak közelében helyezkedik el, míg az ér intimasejtekproliferációját ezzel egyidejűleg nem gátolja. A találmány a fentieszköz alkalmazására vonatkozó eljárást is ismerteti. Ó
HU0402036A 2001-10-25 2002-10-25 Vascular stent or graft coated or impregnated with protein tyrosine kinase inhibitors and method of using same HUP0402036A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34373201P 2001-10-25 2001-10-25
PCT/US2002/034344 WO2003034938A2 (en) 2001-10-25 2002-10-25 Vascular stent or graft coated or impregnated with protein tyrosine kinase inhibitors and method of using same

Publications (2)

Publication Number Publication Date
HUP0402036A2 true HUP0402036A2 (hu) 2005-02-28
HUP0402036A3 HUP0402036A3 (en) 2008-04-28

Family

ID=23347387

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0402036A HUP0402036A3 (en) 2001-10-25 2002-10-25 Vascular stent or graft coated or impregnated with protein tyrosine kinase inhibitors and method of using same

Country Status (18)

Country Link
US (1) US20040044405A1 (hu)
EP (1) EP1441749A4 (hu)
JP (1) JP2006519623A (hu)
KR (1) KR20040051618A (hu)
CN (1) CN1635858A (hu)
BR (1) BR0213497A (hu)
CA (1) CA2464093A1 (hu)
CO (1) CO5580792A2 (hu)
EC (1) ECSP045085A (hu)
HU (1) HUP0402036A3 (hu)
IL (1) IL161583A0 (hu)
MX (1) MXPA04003906A (hu)
NO (1) NO20042133L (hu)
NZ (1) NZ532593A (hu)
PL (1) PL374315A1 (hu)
RU (1) RU2004116068A (hu)
WO (1) WO2003034938A2 (hu)
ZA (1) ZA200403184B (hu)

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US20070196428A1 (en) 2006-02-17 2007-08-23 Thierry Glauser Nitric oxide generating medical devices
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US8372133B2 (en) * 2009-10-05 2013-02-12 480 Biomedical, Inc. Polymeric implant delivery system
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KR101897952B1 (ko) 2011-01-14 2018-09-12 스페로 트리넴, 인코포레이티드 피리미딘 자이라제 및 토포이소머라제 ｉｖ 억제제
US9187953B2 (en) 2011-03-23 2015-11-17 Rytec Corporation Side column configuration for overhead roll-up door assemblies
ES2576298T3 (es) 2011-06-20 2016-07-06 Vertex Pharmaceuticals Incorporated Ésteres de fosfato de inhibidores de girasa y topoisomerasa
US9326951B2 (en) 2011-06-28 2016-05-03 Yale University Cell-free tissue engineered vascular grafts
WO2014015105A1 (en) 2012-07-18 2014-01-23 Vertex Pharmaceuticals Incorporated Solid forms of (r)-2-(5-(2-(3-ethylureido)-6-fluoro-7-(tetrahydrofuran-2-yl)-1h-benzo[d]imidazol-5-yl)pyrimidin-2-yl)propan-2-yl dihydrogen phosphate and salts thereof
EP3057953B1 (en) 2013-10-17 2018-08-15 Vertex Pharmaceuticals Incorporated Co-crystals of (s)-n-methyl-8-(1-((2'-methyl-[4,5'-bipyrimidin]-6-yl)amino)propan-2-yl)quinoline-4-carboxamide and deuterated derivatives thereof as dna-pk inhibitors
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Also Published As

Publication number Publication date
JP2006519623A (ja) 2006-08-31
IL161583A0 (en) 2004-09-27
HUP0402036A3 (en) 2008-04-28
MXPA04003906A (es) 2005-02-17
WO2003034938A2 (en) 2003-05-01
CO5580792A2 (es) 2005-11-30
PL374315A1 (en) 2005-10-03
ZA200403184B (en) 2005-05-12
BR0213497A (pt) 2006-05-23
ECSP045085A (es) 2004-07-23
US20040044405A1 (en) 2004-03-04
CN1635858A (zh) 2005-07-06
CA2464093A1 (en) 2003-05-01
EP1441749A2 (en) 2004-08-04
WO2003034938A3 (en) 2003-11-13
KR20040051618A (ko) 2004-06-18
RU2004116068A (ru) 2005-03-20
NZ532593A (en) 2007-11-30
NO20042133L (no) 2004-07-09
EP1441749A4 (en) 2010-05-19

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Legal Events

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FA9A Lapse of provisional patent protection due to relinquishment or protection considered relinquished