HUP0303319A2 - 9-Dezoxo-9-dihidro-9a-aza-9a-homoeritromicin A és 5-O-dezozaminil-9-dezoxo-9-dihidro-9a-aza-9a-homoeritronolid A 9a-N-[N'-(fenil-szulfonil)karbamoil]-származékai, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények - Google Patents
9-Dezoxo-9-dihidro-9a-aza-9a-homoeritromicin A és 5-O-dezozaminil-9-dezoxo-9-dihidro-9a-aza-9a-homoeritronolid A 9a-N-[N'-(fenil-szulfonil)karbamoil]-származékai, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítményekInfo
- Publication number
- HUP0303319A2 HUP0303319A2 HU0303319A HUP0303319A HUP0303319A2 HU P0303319 A2 HUP0303319 A2 HU P0303319A2 HU 0303319 A HU0303319 A HU 0303319A HU P0303319 A HUP0303319 A HU P0303319A HU P0303319 A2 HUP0303319 A2 HU P0303319A2
- Authority
- HU
- Hungary
- Prior art keywords
- aza
- dihydro
- deoxo
- homoerythronolide
- carbamoyl
- Prior art date
Links
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
A bejelentés a 9-dezoxo-9-dihidro-9a-aza-9a-homoeritromicin A és az 5-O-dezozaminil-9-dezoxo-9dihidro-9a-aza-9a-homoeritronolid A (1)általános képletű 9a-N-[N'-(fenilszulfonil)karbamoil]-származékaira,ezek előállítására és az ezeket tartalmazó, antibakteriális hatásúgyógyszerkészítményekre vonatkozik. Az (1) általános képletben R1jelentése hidrogénatom, alkilcsoport vagy halogénatom és R jelentésehidrogénatom vagy kladinozilcsoport. Ó
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HR20010146A HRP20010146B1 (en) | 2001-02-28 | 2001-02-28 | 9a-N-(N'-(PHENYLSULFONYL)CARBAMOYL) DERIVATIVES OF 9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERYTHROMYCIN A AND OF 5-O-DESOSAMINYL-9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERYTHRONOLIDE A |
PCT/HR2002/000010 WO2002068438A2 (en) | 2001-02-28 | 2002-02-27 | 9a-n-[n'-(phenylsulfonyl)carbamoyl] derivatives of 9-deoxo-9-dihydro-9a-aza-9a-homoerythromycin a and of 5-0-desosaminyl-9-deoxo-9-dihydro-9a-aza-9a-homoerythronolide a |
Publications (2)
Publication Number | Publication Date |
---|---|
HUP0303319A2 true HUP0303319A2 (hu) | 2004-01-28 |
HUP0303319A3 HUP0303319A3 (en) | 2009-10-28 |
Family
ID=10947270
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0303319A HUP0303319A3 (en) | 2001-02-28 | 2002-02-27 | 9a-n[n'-(phanylsulfonyl)carbamoyl] derivatives of 9-deoxo-9-dihydro-9a-aza-9a-homoerythromycina and of 5-o-desosaminyl-9-deoxo-9-dihydro-9a-aza-9a-homoerythronolide a, process for their preparation and pharmaceutical compositions containing them |
Country Status (12)
Country | Link |
---|---|
US (1) | US6852702B2 (hu) |
EP (1) | EP1414835B1 (hu) |
AU (1) | AU2002233564A1 (hu) |
CZ (1) | CZ20032216A3 (hu) |
DE (1) | DE60204024T2 (hu) |
ES (1) | ES2240689T3 (hu) |
HR (1) | HRP20010146B1 (hu) |
HU (1) | HUP0303319A3 (hu) |
PL (1) | PL369063A1 (hu) |
RU (1) | RU2270836C2 (hu) |
SK (1) | SK12112003A3 (hu) |
WO (1) | WO2002068438A2 (hu) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HRP20020885B1 (en) * | 2002-11-11 | 2007-05-31 | GlaxoSmithKline istra�iva�ki centar Zagreb d.o.o. | SUBSTITUTED 9a-N-{N'-[4-(SULFONYL)PHENYLCARBAMOYL]}DERIVATIVES 9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERITHROMYCIN A AND 5-O-DESOZAMINYL-9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERITHRONOLIDE A |
HRP20020886A2 (en) * | 2002-11-11 | 2005-06-30 | PLIVA-ISTRAŽIVAČKI INSTITUT d.o.o. | SUBSTITUTED 9a-N-[N'-(BENZENSULFONYL)CARBAMOYL-γ-AMINOPROPYL) AND 9a-N(N' -(?-CYANOETHIL)-N' -(b |
HRP20020991A2 (en) * | 2002-12-12 | 2005-02-28 | Pliva-Istra�iva�ki institut d.o.o. | N"-Substituted 9a-N-(N'-carbamoyl-Gamma-aminopropyl), 9a-N-(N'? -thiocarbamoyl-Gamma-aminopropyl), 9a-N-(N'-((Beta-cyanoethyl)-N'-carbamoyl-Gamma? -aminopropyl) and 9a-N-(N'-(Beta-cyanoethyl)-N'-thiocarbamoyl-Gamma? -aminopropyl) derivatives of 9-de |
HRP20030381B1 (en) * | 2003-05-14 | 2007-05-31 | GlaxoSmithKline istra�iva�ki centar Zagreb d.o.o. | 3-DECLADINOZYL 9a-N-CARBAMOYL AND 9a-N-THIOCARBAMOYL DERIVATIVES 9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERYTHROMICYNE A |
KR100576336B1 (ko) | 2003-10-30 | 2006-05-03 | 씨제이 주식회사 | 세팔로스포린 유도체의 제조방법 |
US7402568B2 (en) * | 2004-09-29 | 2008-07-22 | Enanta Pharmaceuticals, Inc. | Bicyclic 9a-azalide derivatives |
US7271155B2 (en) | 2005-01-07 | 2007-09-18 | Enanta Pharmaceuticals, Inc. | 9A, 11-2C-bicyclic 9a-azalide derivatives |
ATE429921T1 (de) * | 2005-01-14 | 2009-05-15 | Glaxosmithkline Zagreb | 9a-carbamoyl- und thiocarbamoylazalide mit antimalariawirkung |
CN104119413B (zh) * | 2014-07-29 | 2016-08-24 | 华中农业大学 | 一种土拉霉素残留标示物的合成方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4434000A (en) * | 1979-08-24 | 1984-02-28 | Stauffer Chemical Company | N-(Benzenesulfonyl) carbamates herbicidal antidotes |
GB8521402D0 (en) * | 1985-08-28 | 1985-10-02 | Beecham Group Plc | Chemical compounds |
HRP931480B1 (en) * | 1993-12-08 | 1997-08-31 | Sour Pliva | 9a-N-(N'-CARBAMONYL) and 9a-N-(N'-THIOCARBAMONYL) DERIVATES OF 9-DEOXO-9a-HOMOERYTHROMYCIN A |
US6353096B1 (en) * | 1999-04-01 | 2002-03-05 | Merial | Process of use in converting the 4″(S)-OH functional group of the cladinose unit of an azamacrolide to 4″(R)-NH2 |
HRP990130B1 (en) * | 1999-05-03 | 2004-06-30 | Pliva D D | HALOGEN DERIVATIVES 9a-N-(N'-ARYLCARBAMOYL)- AND 9a-N-(N'-ARYLTHIOCARBAMOYL)-9-DEOXO-9a-AZA-9a OF HOMOERYTHROMYCIN A |
-
2001
- 2001-02-28 HR HR20010146A patent/HRP20010146B1/xx not_active IP Right Cessation
-
2002
- 2002-02-27 SK SK1211-2003A patent/SK12112003A3/sk unknown
- 2002-02-27 EP EP02700494A patent/EP1414835B1/en not_active Expired - Lifetime
- 2002-02-27 HU HU0303319A patent/HUP0303319A3/hu unknown
- 2002-02-27 ES ES02700494T patent/ES2240689T3/es not_active Expired - Lifetime
- 2002-02-27 WO PCT/HR2002/000010 patent/WO2002068438A2/en not_active Application Discontinuation
- 2002-02-27 RU RU2003122785/04A patent/RU2270836C2/ru not_active IP Right Cessation
- 2002-02-27 AU AU2002233564A patent/AU2002233564A1/en not_active Abandoned
- 2002-02-27 CZ CZ20032216A patent/CZ20032216A3/cs unknown
- 2002-02-27 US US10/469,253 patent/US6852702B2/en not_active Expired - Fee Related
- 2002-02-27 DE DE60204024T patent/DE60204024T2/de not_active Expired - Fee Related
- 2002-02-27 PL PL02369063A patent/PL369063A1/xx unknown
Also Published As
Publication number | Publication date |
---|---|
CZ20032216A3 (cs) | 2003-11-12 |
WO2002068438A3 (en) | 2004-02-26 |
SK12112003A3 (sk) | 2003-12-02 |
RU2270836C2 (ru) | 2006-02-27 |
DE60204024T2 (de) | 2006-03-02 |
US20040077558A1 (en) | 2004-04-22 |
DE60204024D1 (de) | 2005-06-09 |
HRP20010146A2 (en) | 2002-12-31 |
HRP20010146B1 (en) | 2005-10-31 |
PL369063A1 (en) | 2005-04-18 |
US6852702B2 (en) | 2005-02-08 |
EP1414835A2 (en) | 2004-05-06 |
WO2002068438A2 (en) | 2002-09-06 |
EP1414835B1 (en) | 2005-05-04 |
HUP0303319A3 (en) | 2009-10-28 |
AU2002233564A1 (en) | 2002-09-12 |
ES2240689T3 (es) | 2005-10-16 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BR0214469A (pt) | 17alfa-alquil-17beta-óxi-estratrienos e produtos intermediários para sua preparação, aplicação dos 17alfa-alquil-17beta-óxi-estratrienos para a preparação de medicamentos bem como preparações farmacêuticas | |
SE9904505D0 (sv) | Novel compounds | |
IS5578A (is) | Bensensúlfónamíð-afleiður og notkun þeirra sem læknislyf | |
MD1233B1 (en) | Erythromycin derivatives, process for their preparation and pharmaceutical composition on base thereof | |
HUP0101999A2 (hu) | 4-Hidroxi-kinolin-3-karboxamid- és -hidrazid-származékok, ezeket tartalmazó gyógyászati készítmények, valamint e vegyületek alkalmazása | |
TR200001973T2 (tr) | 11 ß-halojen-7alfa-ile ikame edilmiş-estratrienler, bu 11ß-halojen-7alfa-ile ikame edilmiş-estratrienleri içeren farmasötik terkiplerin üretimi için yöntem ve ilaç üretiminde kullanımları. | |
WO2000061537A3 (en) | Pharmaceutical compounds | |
IL123293A (en) | Piperidine derivatives, their preparation and pharmaceutical compositions containing them | |
CA2400268A1 (en) | Pyrrolopyrimidinone derivatives, process of preparation and use | |
WO2000061541A8 (en) | Pharmaceutical compounds | |
RS41104A (en) | Sulphonamide derivatives, the preparation thereof and the application of same as medicaments | |
HUP0105437A2 (hu) | Új malonsavszármazékok, előállításuk és alkalmazásuk, valamint e vegyületeket tartalmazó gyógyászati készítmények | |
NO954072D0 (no) | Vannopplöselige camptotecinderivater, fremgangsmåte for deres fremstilling og deres anvendelse som antitumormidler | |
YU13396A (sh) | N-(3-benzofuranil) urea derivati, postupci za njihovo dobijanje, kompozicije koje ih sadrže i njihova upotreba u lekovima | |
HUP0303043A2 (hu) | Orrgyógyászatilag aktív vegyületek | |
HUP0103063A2 (hu) | Új 2H-piridazin-származékok, alkalmazásuk, ilyen hatóanyagot tartalmazó gyógyászati készítmények, és eljárás a hatóanyag előállítására | |
IL94433A0 (en) | Aminophenol derivatives,their preparation and pharmaceutical compositions containing them | |
HUP0303935A2 (hu) | Ketolid baktériumellenes vegyületek | |
HUP0204563A2 (en) | Process for preparation of 3,3-diarylpropylamine derivatives and their intermediates and their use for preparation of pharmaceutical compositions | |
YU56302A (sh) | Derivati 8,8a-dihidro-indeno/1,2-d/taizola, koji su supstituisani u 8a-položaju,postupak za njihovu proizvodnju i njihova primena kod leka npr.kao anorektičnog sredstva | |
MY115211A (en) | Novel amino acid derivatives, their preparation and use | |
HUP0100558A2 (hu) | S-Oxid- és S,S-dioxid-tetrahidrotiopirán-fenil-oxazolidinon-származékok, e vegyületek alkalmazása gyógyászati készítmények előállítására, valamint eljárás e vegyületek gátló hatásának meghatározására humán-monoamin-oxidázzal szemben | |
HUP0102903A2 (hu) | Nokatiacin antibiotikumok, eljárás az előállításukra és a vegyületeket tartalmazó gyógyszerkészítmények | |
HUP0303319A2 (hu) | 9-Dezoxo-9-dihidro-9a-aza-9a-homoeritromicin A és 5-O-dezozaminil-9-dezoxo-9-dihidro-9a-aza-9a-homoeritronolid A 9a-N-[N'-(fenil-szulfonil)karbamoil]-származékai, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények | |
HUP9701660A2 (hu) | 10,13,15-trioxa-triciklo[9.2.1.1. 9.6]pentadekanon-származékok, eljárás ezek előállítására, és az e vegyületeket tartalmazó gyógyászati készítmények |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD9A | Lapse of provisional protection due to non-payment of fees |